Click here to switch to the map view.

The map label for this gene is yciA [H]

Identifier: 57237743

GI number: 57237743

Start: 929915

End: 930328

Strand: Direct

Name: yciA [H]

Synonym: CJE0993

Alternate gene names: 57237743

Gene position: 929915-930328 (Clockwise)

Preceding gene: 57237739

Following gene: 57237753

Centisome position: 52.31

GC content: 35.75

Gene sequence:

>414_bases
ATGAGAGATATGGGAGAACCAAAATTAAAAATTGTAGCTATGCCAAGTGACACAAATCCAGCGGGAAATATTTTTGGCGG
ATGGATACTTTCACAAATCGATTTAGCAGGAGCTATCGCAGCAAGAGAACTTTCTCCTGAACGCGTTGTAACCATCTCTA
TGGATAAAGTAGTTTTTAAAGAACCTGTTTTTATAGGCGATATAATTTCTTGTTACTCTAAAGTTGTAAATGTGGGCAAC
ACTTCAATCAGCGTTGAAGTAGAAGTCACAGCTCAAAGAGTGGATTCTCAAGGTTGTACTTCTTGCATTAATGTAACTTC
GGCTTTAGTAACTTATGTAAGTGTTACAAGAGATGGAAAGAAAAAGCCTATTAGTGAAGAACTTAAAAGAATTCATGGCT
TTTTAAATGCTTAA

Upstream 100 bases:

>100_bases
TTTTCTAACCAATTTAGCTATTTCTTTAAAATTATTCATACTTTTATTCTCCTTTTTAACTTTTTTAATTATAATTCATT
TTTTAAAATAAGGAGTAAAA

Downstream 100 bases:

>100_bases
AGCTTATTTTGTATGATAAAACTTTATCCTTTAAGCTTATCAGCATTTATTTAAACCGCCACTATTGTATTTTTTATCTA
GACATTCTTTGAAAAATTCC

Product: thioesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 137; Mature: 137

Protein sequence:

>137_residues
MRDMGEPKLKIVAMPSDTNPAGNIFGGWILSQIDLAGAIAARELSPERVVTISMDKVVFKEPVFIGDIISCYSKVVNVGN
TSISVEVEVTAQRVDSQGCTSCINVTSALVTYVSVTRDGKKKPISEELKRIHGFLNA

Sequences:

>Translated_137_residues
MRDMGEPKLKIVAMPSDTNPAGNIFGGWILSQIDLAGAIAARELSPERVVTISMDKVVFKEPVFIGDIISCYSKVVNVGN
TSISVEVEVTAQRVDSQGCTSCINVTSALVTYVSVTRDGKKKPISEELKRIHGFLNA
>Mature_137_residues
MRDMGEPKLKIVAMPSDTNPAGNIFGGWILSQIDLAGAIAARELSPERVVTISMDKVVFKEPVFIGDIISCYSKVVNVGN
TSISVEVEVTAQRVDSQGCTSCINVTSALVTYVSVTRDGKKKPISEELKRIHGFLNA

Specific function: Catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA [H]

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family [H]

Homologues:

Organism=Escherichia coli, GI1787506, Length=123, Percent_Identity=41.4634146341463, Blast_Score=111, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006683 [H]

Pfam domain/function: PF03061 4HBT [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 14771; Mature: 14771

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDMGEPKLKIVAMPSDTNPAGNIFGGWILSQIDLAGAIAARELSPERVVTISMDKVVFK
CCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHH
EPVFIGDIISCYSKVVNVGNTSISVEVEVTAQRVDSQGCTSCINVTSALVTYVSVTRDGK
CCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCC
KKPISEELKRIHGFLNA
CCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MRDMGEPKLKIVAMPSDTNPAGNIFGGWILSQIDLAGAIAARELSPERVVTISMDKVVFK
CCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHH
EPVFIGDIISCYSKVVNVGNTSISVEVEVTAQRVDSQGCTSCINVTSALVTYVSVTRDGK
CCCHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCC
KKPISEELKRIHGFLNA
CCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]