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The map label for this gene is mshA [H]

Identifier: 21226752

GI number: 21226752

Start: 780497

End: 781558

Strand: Direct

Name: mshA [H]

Synonym: MM_0650

Alternate gene names: 21226752

Gene position: 780497-781558 (Clockwise)

Preceding gene: 21226751

Following gene: 21226757

Centisome position: 19.05

GC content: 33.33

Gene sequence:

>1062_bases
ATGGAAATTGATTATATAAACGGCCTGAAAACGGACGAAATATTCGGGATGTCAAAATATCAAAGTGAAATCAATAGCAG
GCTAGGGAACATCAAATTAAATAGGATTGAATATCCGGACATATCAAAGACACCTGGGGTTAATAAAATTGTTGAATACT
TTGTATATCCATTCATTGTAAAGAAAGAAGTAACTAAGAATAACGTTAAACATGTGACCCGCCAGGATCTGGCGTTTCTT
CTCGAGCTAATAGATTTAAAAAAAACAATTGTTACCTGCCATGATATTATACCTATTGCATACTATCATACCCAGAACCC
CATATGGAAACTTAATGCAAAAGGATTGAGAAAAGCAGAAAAAATAATTACGGTATCCGAATTTTCTAAAAACGATATTA
TTAAACATATAAGATATCCAGAAGATAAGATAGAGATTATACCTCCTGCTGTAAACCACAATTTATACTATCAAAATCGA
AATAAGTCAATTTTGAAAAAGTATGGAATAAAAGAAGATGAGAAAGTAATCCTGTATGTCGGAGCGGAAGAACCAAGAAA
AAATATTCAAGTTTTAATAAATTCATTCGATAAATTAAAAAGTAAAATTTCACAGATAAAATTATTGAAAGTCGGAACGC
CAAATTACCTGGGAGTAAGAGAAAAACTTCTGAAACAAATAGAGTCCCTAAATTTACAGAAGGATGTTATCTTTGCAGGG
TATGTGCCAGAGAGTGAATTAGCAAAAATATACAATGCTGTAGACTTATTTGTATTTCCATCTTTGTATGAGGGTTTTGG
AATACCCCCTCTCGAAGCTATGGCTTGTGGGACCCCGGTAATAACATCAAACAGCTCTTCACTGCCTGAAGTTGTGGGAG
ATGCTGCTATAATTATAGACCCATACGACGCAAATAAATTTGCTGAAAAAATGTATGAAGTGCTGATAAATGATGGATTG
AAAGAAGAAATTGTCAGAAAGGGATTGAGAAGATCAAAAATGTTTAGCTGGGAAGATTCGGCAAGAAAAACGTTAAAAGT
ATATAAAGAATTTCGGCCTTAA

Upstream 100 bases:

>100_bases
AAAAAGAGTACATAAGGCAAAGTAATAAGACAAATCATAAATTGTTTAATTAAAAGTAACAATTTACAAAGTCATTCCTG
AATTTTTGGGGAACTTAGAG

Downstream 100 bases:

>100_bases
GTCAGAATTCCATCCCGAATCCCCTTTAAGAACGAAATAAAAGACGGCAGAATTTCTTTTCTTTTTTGACGGTATAAGAT
GCCACCAATGATCATCCAGG

Product: mannosyltransferase

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 353; Mature: 353

Protein sequence:

>353_residues
MEIDYINGLKTDEIFGMSKYQSEINSRLGNIKLNRIEYPDISKTPGVNKIVEYFVYPFIVKKEVTKNNVKHVTRQDLAFL
LELIDLKKTIVTCHDIIPIAYYHTQNPIWKLNAKGLRKAEKIITVSEFSKNDIIKHIRYPEDKIEIIPPAVNHNLYYQNR
NKSILKKYGIKEDEKVILYVGAEEPRKNIQVLINSFDKLKSKISQIKLLKVGTPNYLGVREKLLKQIESLNLQKDVIFAG
YVPESELAKIYNAVDLFVFPSLYEGFGIPPLEAMACGTPVITSNSSSLPEVVGDAAIIIDPYDANKFAEKMYEVLINDGL
KEEIVRKGLRRSKMFSWEDSARKTLKVYKEFRP

Sequences:

>Translated_353_residues
MEIDYINGLKTDEIFGMSKYQSEINSRLGNIKLNRIEYPDISKTPGVNKIVEYFVYPFIVKKEVTKNNVKHVTRQDLAFL
LELIDLKKTIVTCHDIIPIAYYHTQNPIWKLNAKGLRKAEKIITVSEFSKNDIIKHIRYPEDKIEIIPPAVNHNLYYQNR
NKSILKKYGIKEDEKVILYVGAEEPRKNIQVLINSFDKLKSKISQIKLLKVGTPNYLGVREKLLKQIESLNLQKDVIFAG
YVPESELAKIYNAVDLFVFPSLYEGFGIPPLEAMACGTPVITSNSSSLPEVVGDAAIIIDPYDANKFAEKMYEVLINDGL
KEEIVRKGLRRSKMFSWEDSARKTLKVYKEFRP
>Mature_353_residues
MEIDYINGLKTDEIFGMSKYQSEINSRLGNIKLNRIEYPDISKTPGVNKIVEYFVYPFIVKKEVTKNNVKHVTRQDLAFL
LELIDLKKTIVTCHDIIPIAYYHTQNPIWKLNAKGLRKAEKIITVSEFSKNDIIKHIRYPEDKIEIIPPAVNHNLYYQNR
NKSILKKYGIKEDEKVILYVGAEEPRKNIQVLINSFDKLKSKISQIKLLKVGTPNYLGVREKLLKQIESLNLQKDVIFAG
YVPESELAKIYNAVDLFVFPSLYEGFGIPPLEAMACGTPVITSNSSSLPEVVGDAAIIIDPYDANKFAEKMYEVLINDGL
KEEIVRKGLRRSKMFSWEDSARKTLKVYKEFRP

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790061, Length=230, Percent_Identity=26.5217391304348, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17532709, Length=239, Percent_Identity=23.4309623430962, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI9755344, Length=268, Percent_Identity=24.6268656716418, Blast_Score=74, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 40611; Mature: 40611

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIDYINGLKTDEIFGMSKYQSEINSRLGNIKLNRIEYPDISKTPGVNKIVEYFVYPFIV
CCCCCCCCCCCHHHHCHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHH
KKEVTKNNVKHVTRQDLAFLLELIDLKKTIVTCHDIIPIAYYHTQNPIWKLNAKGLRKAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEECHHHHHHHH
KIITVSEFSKNDIIKHIRYPEDKIEIIPPAVNHNLYYQNRNKSILKKYGIKEDEKVILYV
HEEEHHHCCHHHHHHHHCCCCCCEEEECCCCCCCEEEECCCHHHHHHCCCCCCCEEEEEE
GAEEPRKNIQVLINSFDKLKSKISQIKLLKVGTPNYLGVREKLLKQIESLNLQKDVIFAG
CCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEE
YVPESELAKIYNAVDLFVFPSLYEGFGIPPLEAMACGTPVITSNSSSLPEVVGDAAIIID
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEECCCCCCHHHHCCEEEEEE
PYDANKFAEKMYEVLINDGLKEEIVRKGLRRSKMFSWEDSARKTLKVYKEFRP
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEIDYINGLKTDEIFGMSKYQSEINSRLGNIKLNRIEYPDISKTPGVNKIVEYFVYPFIV
CCCCCCCCCCCHHHHCHHHHHHHHHHHHCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHH
KKEVTKNNVKHVTRQDLAFLLELIDLKKTIVTCHDIIPIAYYHTQNPIWKLNAKGLRKAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCEEEECHHHHHHHH
KIITVSEFSKNDIIKHIRYPEDKIEIIPPAVNHNLYYQNRNKSILKKYGIKEDEKVILYV
HEEEHHHCCHHHHHHHHCCCCCCEEEECCCCCCCEEEECCCHHHHHHCCCCCCCEEEEEE
GAEEPRKNIQVLINSFDKLKSKISQIKLLKVGTPNYLGVREKLLKQIESLNLQKDVIFAG
CCCCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEEEE
YVPESELAKIYNAVDLFVFPSLYEGFGIPPLEAMACGTPVITSNSSSLPEVVGDAAIIID
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCEEECCCCCCHHHHCCEEEEEE
PYDANKFAEKMYEVLINDGLKEEIVRKGLRRSKMFSWEDSARKTLKVYKEFRP
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA