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The map label for this gene is arsC [H]

Identifier: 21226676

GI number: 21226676

Start: 700824

End: 701276

Strand: Direct

Name: arsC [H]

Synonym: MM_0574

Alternate gene names: 21226676

Gene position: 700824-701276 (Clockwise)

Preceding gene: 21226675

Following gene: 21226684

Centisome position: 17.11

GC content: 46.14

Gene sequence:

>453_bases
ATGACATCACAAGAAAAGAAGAAGGTCCTCTTTCTGTGCACCCATAACTCAGCCAGGTCCCAGATGGCGGAAGGCCTTTT
GAGGGCTATTCATGGAGATAGATACGAAGCTTACAGTGCCGGCATCAAGGCCACAAATCTTGACCCTCGTGCTGTAATGG
TCATGAAGGAGATAGGCATCGATATATCCAGTCAGCTCTCCAAAACTCCCAAAACATTCCAGAATATCATTTTTGACATT
GCAGTCACAGTCTGTGATAGTGCCAGAGTGTCATGTCCGATATGCAGCACGAATCTGGACCCTCCGACAGAAATTCCCAG
AGCAAGAGAAGTAATTCACAAAAGTTTTGAAGACCCCGCCACAGCCGTGGGATCAGAAGAAGAGCAGCTCGAAGTTTTCC
GTCAGGTCAGAGACGAGATAAAATACTGGATTATTCAGACATTTGGGAAATGA

Upstream 100 bases:

>100_bases
ACCACACATGAACGCGGCTCTATCCGGTACAACGCGGGAGAAAAAGAAATCAAAACAAATAATCCAATAATTTATAGAAC
ATGATAAGATGGTGATAAGC

Downstream 100 bases:

>100_bases
CCCGAAGTTAACGGATTATAGGAATAACTTTGAATAATATCTATGACGTGCTCCCAAAAAGATTTTAAATATCCAGCATA
AAAAATAACACTTCTTTATT

Product: arsenate reductase

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MTSQEKKKVLFLCTHNSARSQMAEGLLRAIHGDRYEAYSAGIKATNLDPRAVMVMKEIGIDISSQLSKTPKTFQNIIFDI
AVTVCDSARVSCPICSTNLDPPTEIPRAREVIHKSFEDPATAVGSEEEQLEVFRQVRDEIKYWIIQTFGK

Sequences:

>Translated_150_residues
MTSQEKKKVLFLCTHNSARSQMAEGLLRAIHGDRYEAYSAGIKATNLDPRAVMVMKEIGIDISSQLSKTPKTFQNIIFDI
AVTVCDSARVSCPICSTNLDPPTEIPRAREVIHKSFEDPATAVGSEEEQLEVFRQVRDEIKYWIIQTFGK
>Mature_149_residues
TSQEKKKVLFLCTHNSARSQMAEGLLRAIHGDRYEAYSAGIKATNLDPRAVMVMKEIGIDISSQLSKTPKTFQNIIFDIA
VTVCDSARVSCPICSTNLDPPTEIPRAREVIHKSFEDPATAVGSEEEQLEVFRQVRDEIKYWIIQTFGK

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16848; Mature: 16717

Theoretical pI: Translated: 6.76; Mature: 6.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSQEKKKVLFLCTHNSARSQMAEGLLRAIHGDRYEAYSAGIKATNLDPRAVMVMKEIGI
CCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHCC
DISSQLSKTPKTFQNIIFDIAVTVCDSARVSCPICSTNLDPPTEIPRAREVIHKSFEDPA
CHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCHHHHHHHHHHCCCCH
TAVGSEEEQLEVFRQVRDEIKYWIIQTFGK
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TSQEKKKVLFLCTHNSARSQMAEGLLRAIHGDRYEAYSAGIKATNLDPRAVMVMKEIGI
CCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHHHHHHHHCC
DISSQLSKTPKTFQNIIFDIAVTVCDSARVSCPICSTNLDPPTEIPRAREVIHKSFEDPA
CHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCCCCCHHHHHHHHHHCCCCH
TAVGSEEEQLEVFRQVRDEIKYWIIQTFGK
HHCCCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA