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The map label for this gene is pfkC [H]

Identifier: 21226574

GI number: 21226574

Start: 595615

End: 597156

Strand: Reverse

Name: pfkC [H]

Synonym: MM_0472

Alternate gene names: 21226574

Gene position: 597156-595615 (Counterclockwise)

Preceding gene: 21226575

Following gene: 21226573

Centisome position: 14.58

GC content: 45.4

Gene sequence:

>1542_bases
ATGAAAATACTTTGTGGCTATAATGTAAATATAGACTCCGTATACAGGATAAACGGAGCTGAAATCTCGGAACTGCTGAA
GTCGTTTGAAAAGGCTCAAATTCTTGAAAAAATGGAGAACCCTCCCGGGAAAATCCTTTCAGAGTCTGATTTCGTGGCAG
GGCTAGTTTACTGTATGAAAAACGGTTGTGGAGCCGAATGGCTTGTTTTTGAACAGGGAGTCTTTGAGTTTTTGAAGAAC
CGGTATCTTGAAAAGTCCATTGTAAGAATGGGCGGAAATGCAGGGATTATGGCAAACGTCCTTTCCGAGATGGGGGCTTC
GAGAGTCGTCCCGAATGTTGCTGTTCCTTCAGAAACCCAGCTCTCTTTATTCTCAAAAAAAGCAGTCTATTTTCCGGGCA
CTCCTCTTCAGGCAGATAAAGAGCCGGGAAAAGTAAACCCTGAAGACGAATCTATAAAAAATACTCAGGAATCTGAAGAT
GCGCGTAAATCTGAAGATGCACATAAATCTGAAGATGCACATAATGCACGGACAGGCAGCACAGGTACTTCCAGAACCCA
GGACCCTATCCATTTCGTTTTTGATTTTTCAGAAGGCGAAACTTTTTCCCTTTATGGAAAAGAAATCCGGGTCCCCAGGG
AAAACCGCTTTATTGCGACCTGCGACCACCTGAACTTCAGGCTCTTTACCAGCGCTGCTTTTGAGAATTATGCCCTGGAC
AATGCAGGAGAAATGGACGGGGCACTCATATCAGGCTTCCATCTCCTTCTTGATACCTATCCTGACGGCAGCACTTACGG
AGAATATCTTGAAAATTCTTTTTCCAGGCTTAAAACCTGGAAATCAAAAAATGAAAATCTCAGGATTCATGTGGAACTGG
GGCATTTCGCAAGCAGGGATATAGCAAACTCTGTATTTTTAAAATCTGCCGGAATTTCGGACAGCATCGGAATGAACGAA
GACGAGCTTGCAATCTTTAATTACCTGCACGGAGTCCCTGCTGAAGGCCTTTTGCGTATGGAAGCCGAGTCCATAGGAAA
GGCAGCCTGTAAACTTGCTTTTATGAACGGGCTTGAGAGACTCTTTATTCATACAAGGGAGTTTGTTCTGACTGTATCAG
GGCCGGATTCCGGAAATTCTGACAGTTCAGGAATTTCAGAAAAATGGGATGAAAAAAAATGGAAAGACAGAGAAAGTCCA
GCTCTGCTGAAGGAAGCCGGGAAAATAATCGAAGCCATGAGCTTCGGACAGAAGTGTGCAGGAGCATATGCCGCTTCAGG
GAAGCTCGAAGGGCGGGAATTTATGGAAAAAGAGGCTTTGAAACTTCAGGAAAGCGAGATTGGAAGAAAGCAGTTGCAGC
TTTTCCTGAAAGCCTTCGGAGGAGCTGCCTGTGGACGGGGAGCATATGCTTTAATGGAAGGCTGTATGCTCTGTATTCTC
CCCACTCTTCTCTGCAAATCCCCGATAACTACGGTTGGGCTCGGGGACACGCTGACTGCGGGAACTTTTTTGAGGGGGCT
TGAGCTGGATGTACAGACTTGA

Upstream 100 bases:

>100_bases
TAGATTCTTATCTTCCACGCTTTATAACGGATTAAGTGATTCCCAGCATGGAAGCCTGAAAAAGGCTCCCTCTCCGTTTT
AATTTACAGGAACAGGTCAG

Downstream 100 bases:

>100_bases
TCCCGATTTTTTCAACCTTGATTATACCCTCGACTGCGGCCAGGTCTTCCGCTGGGAAAAGAATGGAGACTGGTGGACAG
GGGTTGTAGGAAACAATGTT

Product: ADP-dependent glucokinase

Products: NA

Alternate protein names: ADP-dependent phosphofructokinase; ADP-Pfk [H]

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MKILCGYNVNIDSVYRINGAEISELLKSFEKAQILEKMENPPGKILSESDFVAGLVYCMKNGCGAEWLVFEQGVFEFLKN
RYLEKSIVRMGGNAGIMANVLSEMGASRVVPNVAVPSETQLSLFSKKAVYFPGTPLQADKEPGKVNPEDESIKNTQESED
ARKSEDAHKSEDAHNARTGSTGTSRTQDPIHFVFDFSEGETFSLYGKEIRVPRENRFIATCDHLNFRLFTSAAFENYALD
NAGEMDGALISGFHLLLDTYPDGSTYGEYLENSFSRLKTWKSKNENLRIHVELGHFASRDIANSVFLKSAGISDSIGMNE
DELAIFNYLHGVPAEGLLRMEAESIGKAACKLAFMNGLERLFIHTREFVLTVSGPDSGNSDSSGISEKWDEKKWKDRESP
ALLKEAGKIIEAMSFGQKCAGAYAASGKLEGREFMEKEALKLQESEIGRKQLQLFLKAFGGAACGRGAYALMEGCMLCIL
PTLLCKSPITTVGLGDTLTAGTFLRGLELDVQT

Sequences:

>Translated_513_residues
MKILCGYNVNIDSVYRINGAEISELLKSFEKAQILEKMENPPGKILSESDFVAGLVYCMKNGCGAEWLVFEQGVFEFLKN
RYLEKSIVRMGGNAGIMANVLSEMGASRVVPNVAVPSETQLSLFSKKAVYFPGTPLQADKEPGKVNPEDESIKNTQESED
ARKSEDAHKSEDAHNARTGSTGTSRTQDPIHFVFDFSEGETFSLYGKEIRVPRENRFIATCDHLNFRLFTSAAFENYALD
NAGEMDGALISGFHLLLDTYPDGSTYGEYLENSFSRLKTWKSKNENLRIHVELGHFASRDIANSVFLKSAGISDSIGMNE
DELAIFNYLHGVPAEGLLRMEAESIGKAACKLAFMNGLERLFIHTREFVLTVSGPDSGNSDSSGISEKWDEKKWKDRESP
ALLKEAGKIIEAMSFGQKCAGAYAASGKLEGREFMEKEALKLQESEIGRKQLQLFLKAFGGAACGRGAYALMEGCMLCIL
PTLLCKSPITTVGLGDTLTAGTFLRGLELDVQT
>Mature_513_residues
MKILCGYNVNIDSVYRINGAEISELLKSFEKAQILEKMENPPGKILSESDFVAGLVYCMKNGCGAEWLVFEQGVFEFLKN
RYLEKSIVRMGGNAGIMANVLSEMGASRVVPNVAVPSETQLSLFSKKAVYFPGTPLQADKEPGKVNPEDESIKNTQESED
ARKSEDAHKSEDAHNARTGSTGTSRTQDPIHFVFDFSEGETFSLYGKEIRVPRENRFIATCDHLNFRLFTSAAFENYALD
NAGEMDGALISGFHLLLDTYPDGSTYGEYLENSFSRLKTWKSKNENLRIHVELGHFASRDIANSVFLKSAGISDSIGMNE
DELAIFNYLHGVPAEGLLRMEAESIGKAACKLAFMNGLERLFIHTREFVLTVSGPDSGNSDSSGISEKWDEKKWKDRESP
ALLKEAGKIIEAMSFGQKCAGAYAASGKLEGREFMEKEALKLQESEIGRKQLQLFLKAFGGAACGRGAYALMEGCMLCIL
PTLLCKSPITTVGLGDTLTAGTFLRGLELDVQT

Specific function: Catalyzes the phosphorylation of fructose 6-phosphate to fructose 1,6-bisphosphate using ADP as the phosphate donor [H]

COG id: COG4809

COG function: function code G; Archaeal ADP-dependent phosphofructokinase/glucokinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ADPK (ADP-dependent kinase) domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007666
- InterPro:   IPR015990
- InterPro:   IPR011790 [H]

Pfam domain/function: PF04587 ADP_PFK_GK [H]

EC number: =2.7.1.146 [H]

Molecular weight: Translated: 56432; Mature: 56432

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILCGYNVNIDSVYRINGAEISELLKSFEKAQILEKMENPPGKILSESDFVAGLVYCMK
CEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
NGCGAEWLVFEQGVFEFLKNRYLEKSIVRMGGNAGIMANVLSEMGASRVVPNVAVPSETQ
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHCCCCCCCCCCCH
LSLFSKKAVYFPGTPLQADKEPGKVNPEDESIKNTQESEDARKSEDAHKSEDAHNARTGS
HHHHHCCEEECCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCC
TGTSRTQDPIHFVFDFSEGETFSLYGKEIRVPRENRFIATCDHLNFRLFTSAAFENYALD
CCCCCCCCCEEEEEECCCCCEEEEECCEEECCCCCCEEEEECCCCEEEEEHHHHHHHCCC
NAGEMDGALISGFHLLLDTYPDGSTYGEYLENSFSRLKTWKSKNENLRIHVELGHFASRD
CCCCCCHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHH
IANSVFLKSAGISDSIGMNEDELAIFNYLHGVPAEGLLRMEAESIGKAACKLAFMNGLER
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LFIHTREFVLTVSGPDSGNSDSSGISEKWDEKKWKDRESPALLKEAGKIIEAMSFGQKCA
HHHEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
GAYAASGKLEGREFMEKEALKLQESEIGRKQLQLFLKAFGGAACGRGAYALMEGCMLCIL
CCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
PTLLCKSPITTVGLGDTLTAGTFLRGLELDVQT
HHHHHCCCCCEECCCCHHHHHHHHHCCEEEECC
>Mature Secondary Structure
MKILCGYNVNIDSVYRINGAEISELLKSFEKAQILEKMENPPGKILSESDFVAGLVYCMK
CEEEEECCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
NGCGAEWLVFEQGVFEFLKNRYLEKSIVRMGGNAGIMANVLSEMGASRVVPNVAVPSETQ
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHCCCCCCCCCCCH
LSLFSKKAVYFPGTPLQADKEPGKVNPEDESIKNTQESEDARKSEDAHKSEDAHNARTGS
HHHHHCCEEECCCCCCCCCCCCCCCCCCHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCCC
TGTSRTQDPIHFVFDFSEGETFSLYGKEIRVPRENRFIATCDHLNFRLFTSAAFENYALD
CCCCCCCCCEEEEEECCCCCEEEEECCEEECCCCCCEEEEECCCCEEEEEHHHHHHHCCC
NAGEMDGALISGFHLLLDTYPDGSTYGEYLENSFSRLKTWKSKNENLRIHVELGHFASRD
CCCCCCHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCHHHHH
IANSVFLKSAGISDSIGMNEDELAIFNYLHGVPAEGLLRMEAESIGKAACKLAFMNGLER
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LFIHTREFVLTVSGPDSGNSDSSGISEKWDEKKWKDRESPALLKEAGKIIEAMSFGQKCA
HHHEEEEEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
GAYAASGKLEGREFMEKEALKLQESEIGRKQLQLFLKAFGGAACGRGAYALMEGCMLCIL
CCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
PTLLCKSPITTVGLGDTLTAGTFLRGLELDVQT
HHHHHCCCCCEECCCCHHHHHHHHHCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]