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The map label for this gene is hsdM [C]

Identifier: 21226531

GI number: 21226531

Start: 546056

End: 547786

Strand: Direct

Name: hsdM [C]

Synonym: MM_0429

Alternate gene names: 21226531

Gene position: 546056-547786 (Clockwise)

Preceding gene: 21226524

Following gene: 21226532

Centisome position: 13.33

GC content: 46.27

Gene sequence:

>1731_bases
ATGATTGATATCGAACAGCAATTTTTAAATGATCTCGATAACCAGCTCTGGAGGGCTGCCGACAAACTGCGCTCTAACCT
GGATGCCGCCAATTACAAACATGTGGTGTTAGGGCTTATTTTCCTTAAATACGTGTCTGATGCCTTCGAAGAGCGCCAGC
AAGAACTTACTGAGCTGTTTCAAAAAGACGATGACGACAATATCTATTACCTGCCCCGCGAAGATTATGACAGCGATGAA
GCCTACCAGCAAGCCATAGCAGAAGAGCTGGAAATTGGTGACTACTACACCGAAAAAAATGTTTTCTGGGTACCCAAAAC
CGCCCGCTGGAACAAACTGAGAGATGTAATTACTCTTCCCACTGGCAGTGTTATCTGGCAAGACGAACAGGGCGAAGACG
TTAAACTGAGATCCGTGTCATGGCTGATTGATAATGCATTCGATGACATTGAAAAAGCCAACCCAAAGCTCAAAGGCATT
CTCAACCGCATCAGCCAATACCAATTGGATGCAGACAAGCTTATTGGCCTGATCAATGAATTTAGCCTTACCAGTTTTAA
TAACCCCGAGTACAACGGCGAAAAACTTAACCTTAAGTCCAAAGACATTCTCGGCCATGTTTACGAATACTTTTTGGGCC
AATTTGCCCTTGCCGAAGGTAAGCAGGGAGGCCAGTATTATACACCCAAATCTATCGTTACTTTGATCGTGGAAATGCTG
GAGCCCTACAAAGGCCGTGTGTACGACCCAGCCATGGGCAGCGGCGGTTTTTTTGTTTCGAGTGACAAATTCATTGAAAA
ACACGCCAATGTAAAACATTACAATGCTTCCGAACAGAAAAAACAAATTTCGGTATACGGGCAGGAATCCAACCCCACCA
CCTGGAAGCTTGCTGCCATGAACATGGTCATTCGTGGCATTGATTTTAATTTTGGCAAAAAGAACGCTGACTCCTTTTTA
GACGACCAGCACCCCGACCTGCGAGCCGACTTTGTCATGACCAACCCGCCTTTTAATATGAAGGACTGGTGGCACGAAAA
GCTTGCCGACGATCCGCGCTGGACCATCAATACCAACGGCGAAAAACGCATCCTTACTCCACCGACGGGTAACGCCAACT
TCGCATGGATGTTGCATATGCTGTACCACCTGGCTCCCACGGGCAGCATGGCGCTTTTACTGGCTAACGGTTCCATGAGC
AGTAACACCAATAATGAAGGGGAAATTCGCAAAACTCTTGTCGAGCAAGACCTGGTGGAATGTATGGTAGCACTTCCGGG
ACAACTCTTTACCAACACCCAAATCCCCGCATGTATCTGGTTTTTAACCAAAGATAAGAATGCTAAAAATGGCAAGCGTG
ATCGCCGCGGCCAGGTGCTGTTTATTGATGCTCGCAAATTGGGTTATATGAAAGACCGCGTACTGCGGGATTTTAAAGAT
GAAGATATCCAGAAACTCGCAGATACCTTCCATAATTGGCAGCAAGAATGGTCAGAAGAAAATAACCAGGCAGGTTTCTG
TTTCTCCGCTGATCTCGCCTTAATCCGAAAGAATGACTTTGTATTGACCCCTGGCCGCTATGTGGGCGCAGAAGCTGAGG
AGGACGATGGTATATTATTTGCCGATAAAATGGCTGTACTCACCAGCCAGTTAAAAGAGCAGTTTGAAGAAAGCAGGAAA
CTGGAAGCTCAGATTAAACAGAATTTGGCGGGGTTGGGCTTCGATGTTTGA

Upstream 100 bases:

>100_bases
GCCATTTATGGCTAATATCTCTATTTATAAATGTTGATAAACTAATTACTGCACTGTTTTATCAAATTGATTCACAATTG
AATAACGGAAGGCATTAATA

Downstream 100 bases:

>100_bases
GAAAACAATAGCTCTAAATGAGTTTATCATACTTCAAAGAGGATTTGACCTTCCGGCAAGCGATAGGAAAAATGGGAATG
TACCTGTCGTTGCTTCAACA

Product: type I restriction-modification system methylation subunit

Products: NA

Alternate protein names: M.HindVIIP [H]

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MIDIEQQFLNDLDNQLWRAADKLRSNLDAANYKHVVLGLIFLKYVSDAFEERQQELTELFQKDDDDNIYYLPREDYDSDE
AYQQAIAEELEIGDYYTEKNVFWVPKTARWNKLRDVITLPTGSVIWQDEQGEDVKLRSVSWLIDNAFDDIEKANPKLKGI
LNRISQYQLDADKLIGLINEFSLTSFNNPEYNGEKLNLKSKDILGHVYEYFLGQFALAEGKQGGQYYTPKSIVTLIVEML
EPYKGRVYDPAMGSGGFFVSSDKFIEKHANVKHYNASEQKKQISVYGQESNPTTWKLAAMNMVIRGIDFNFGKKNADSFL
DDQHPDLRADFVMTNPPFNMKDWWHEKLADDPRWTINTNGEKRILTPPTGNANFAWMLHMLYHLAPTGSMALLLANGSMS
SNTNNEGEIRKTLVEQDLVECMVALPGQLFTNTQIPACIWFLTKDKNAKNGKRDRRGQVLFIDARKLGYMKDRVLRDFKD
EDIQKLADTFHNWQQEWSEENNQAGFCFSADLALIRKNDFVLTPGRYVGAEAEEDDGILFADKMAVLTSQLKEQFEESRK
LEAQIKQNLAGLGFDV

Sequences:

>Translated_576_residues
MIDIEQQFLNDLDNQLWRAADKLRSNLDAANYKHVVLGLIFLKYVSDAFEERQQELTELFQKDDDDNIYYLPREDYDSDE
AYQQAIAEELEIGDYYTEKNVFWVPKTARWNKLRDVITLPTGSVIWQDEQGEDVKLRSVSWLIDNAFDDIEKANPKLKGI
LNRISQYQLDADKLIGLINEFSLTSFNNPEYNGEKLNLKSKDILGHVYEYFLGQFALAEGKQGGQYYTPKSIVTLIVEML
EPYKGRVYDPAMGSGGFFVSSDKFIEKHANVKHYNASEQKKQISVYGQESNPTTWKLAAMNMVIRGIDFNFGKKNADSFL
DDQHPDLRADFVMTNPPFNMKDWWHEKLADDPRWTINTNGEKRILTPPTGNANFAWMLHMLYHLAPTGSMALLLANGSMS
SNTNNEGEIRKTLVEQDLVECMVALPGQLFTNTQIPACIWFLTKDKNAKNGKRDRRGQVLFIDARKLGYMKDRVLRDFKD
EDIQKLADTFHNWQQEWSEENNQAGFCFSADLALIRKNDFVLTPGRYVGAEAEEDDGILFADKMAVLTSQLKEQFEESRK
LEAQIKQNLAGLGFDV
>Mature_576_residues
MIDIEQQFLNDLDNQLWRAADKLRSNLDAANYKHVVLGLIFLKYVSDAFEERQQELTELFQKDDDDNIYYLPREDYDSDE
AYQQAIAEELEIGDYYTEKNVFWVPKTARWNKLRDVITLPTGSVIWQDEQGEDVKLRSVSWLIDNAFDDIEKANPKLKGI
LNRISQYQLDADKLIGLINEFSLTSFNNPEYNGEKLNLKSKDILGHVYEYFLGQFALAEGKQGGQYYTPKSIVTLIVEML
EPYKGRVYDPAMGSGGFFVSSDKFIEKHANVKHYNASEQKKQISVYGQESNPTTWKLAAMNMVIRGIDFNFGKKNADSFL
DDQHPDLRADFVMTNPPFNMKDWWHEKLADDPRWTINTNGEKRILTPPTGNANFAWMLHMLYHLAPTGSMALLLANGSMS
SNTNNEGEIRKTLVEQDLVECMVALPGQLFTNTQIPACIWFLTKDKNAKNGKRDRRGQVLFIDARKLGYMKDRVLRDFKD
EDIQKLADTFHNWQQEWSEENNQAGFCFSADLALIRKNDFVLTPGRYVGAEAEEDDGILFADKMAVLTSQLKEQFEESRK
LEAQIKQNLAGLGFDV

Specific function: Methylation of specific adenine residues; required for both restriction and modification activities [H]

COG id: COG0286

COG function: function code V; Type I restriction-modification system methyltransferase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the N(4)/N(6)-methyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1790808, Length=262, Percent_Identity=27.0992366412214, Blast_Score=95, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003356
- InterPro:   IPR002296 [H]

Pfam domain/function: PF02384 N6_Mtase [H]

EC number: =2.1.1.72 [H]

Molecular weight: Translated: 66258; Mature: 66258

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDIEQQFLNDLDNQLWRAADKLRSNLDAANYKHVVLGLIFLKYVSDAFEERQQELTELF
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKDDDDNIYYLPREDYDSDEAYQQAIAEELEIGDYYTEKNVFWVPKTARWNKLRDVITLP
HCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCEEECCCEEECCCCCCHHHHHHEEECC
TGSVIWQDEQGEDVKLRSVSWLIDNAFDDIEKANPKLKGILNRISQYQLDADKLIGLINE
CCCEEEECCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
FSLTSFNNPEYNGEKLNLKSKDILGHVYEYFLGQFALAEGKQGGQYYTPKSIVTLIVEML
HCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHH
EPYKGRVYDPAMGSGGFFVSSDKFIEKHANVKHYNASEQKKQISVYGQESNPTTWKLAAM
CCCCCCEECCCCCCCCEEECCCHHHHHCCCCCCCCCHHHHCEEEEEECCCCCCEEEHHHH
NMVIRGIDFNFGKKNADSFLDDQHPDLRADFVMTNPPFNMKDWWHEKLADDPRWTINTNG
HHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEEECCC
EKRILTPPTGNANFAWMLHMLYHLAPTGSMALLLANGSMSSNTNNEGEIRKTLVEQDLVE
CEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
CMVALPGQLFTNTQIPACIWFLTKDKNAKNGKRDRRGQVLFIDARKLGYMKDRVLRDFKD
HHHHCCCHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCH
EDIQKLADTFHNWQQEWSEENNQAGFCFSADLALIRKNDFVLTPGRYVGAEAEEDDGILF
HHHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEEEECCCEEECCCCEECCCCCCCCCEEE
ADKMAVLTSQLKEQFEESRKLEAQIKQNLAGLGFDV
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MIDIEQQFLNDLDNQLWRAADKLRSNLDAANYKHVVLGLIFLKYVSDAFEERQQELTELF
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QKDDDDNIYYLPREDYDSDEAYQQAIAEELEIGDYYTEKNVFWVPKTARWNKLRDVITLP
HCCCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCEEECCCEEECCCCCCHHHHHHEEECC
TGSVIWQDEQGEDVKLRSVSWLIDNAFDDIEKANPKLKGILNRISQYQLDADKLIGLINE
CCCEEEECCCCCCEEEEHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHHHH
FSLTSFNNPEYNGEKLNLKSKDILGHVYEYFLGQFALAEGKQGGQYYTPKSIVTLIVEML
HCCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECHHHHHHHHHHHH
EPYKGRVYDPAMGSGGFFVSSDKFIEKHANVKHYNASEQKKQISVYGQESNPTTWKLAAM
CCCCCCEECCCCCCCCEEECCCHHHHHCCCCCCCCCHHHHCEEEEEECCCCCCEEEHHHH
NMVIRGIDFNFGKKNADSFLDDQHPDLRADFVMTNPPFNMKDWWHEKLADDPRWTINTNG
HHHHHCCCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCEEEECCC
EKRILTPPTGNANFAWMLHMLYHLAPTGSMALLLANGSMSSNTNNEGEIRKTLVEQDLVE
CEEEECCCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
CMVALPGQLFTNTQIPACIWFLTKDKNAKNGKRDRRGQVLFIDARKLGYMKDRVLRDFKD
HHHHCCCHHHCCCCCCEEEEEEECCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHCCH
EDIQKLADTFHNWQQEWSEENNQAGFCFSADLALIRKNDFVLTPGRYVGAEAEEDDGILF
HHHHHHHHHHHHHHHHHHCCCCCCCEEEECCEEEEECCCEEECCCCEECCCCCCCCCEEE
ADKMAVLTSQLKEQFEESRKLEAQIKQNLAGLGFDV
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]