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The map label for this gene is 21226532

Identifier: 21226532

GI number: 21226532

Start: 547779

End: 549098

Strand: Direct

Name: 21226532

Synonym: MM_0430

Alternate gene names: NA

Gene position: 547779-549098 (Clockwise)

Preceding gene: 21226531

Following gene: 21226533

Centisome position: 13.37

GC content: 38.71

Gene sequence:

>1320_bases
ATGTTTGAGAAAACAATAGCTCTAAATGAGTTTATCATACTTCAAAGAGGATTTGACCTTCCGGCAAGCGATAGGAAAAA
TGGGAATGTACCTGTCGTTGCTTCAACAGGGATAGGAGGCTATCACGATGAAGCAAAAGTTGAAGCTCCTGGAGTAGTTA
TTGGTCGAAGTGGCAGTATTGGGGGGGGGCAATTCATCACAGAAAATTTTTGGCCACTAAATACAACATTATGGGTTAAA
GATTTTAAAGGGCATCATCCTCGCTATGTTTACTATCTTCTAAAAAGTATAGATTTCAAACAATTTAATGTTGGTTCTGG
TGTTCCGACATTAAACAGGAACCATTTGTCGAGCATTCTTGTTTCAGATATTGGCATTAATTATGAGACGAAAATCGCAG
AAATACTTGGCAAAATTGACGACAAAATAGAACTCAATCTCAAGATCAACTATACTCTCGAAGCAATGGCACAAGCCATT
TTCAAAAGCTGGTTTGTAGATTTTGATCCGGTCAAAGCCAAAATCGCCGCCATTGAAGCCGGTGAAGATTCTGATGGTGT
AACTCGTGCCGCTATTAGTGCCATCTCCGGCAAGACCGATGAAGAGTTAGACCAATTACAGGCCGAGCAGCCAGAACACT
ACATACAACTCAAAAACACCGCCGAACTGTTTCCCTCCACAATGCAGGAGTCGGAATTGGGAGAGATTCCAGATGGGTGG
GAAGTAAAATCACTCTATGATTTTGCTCAATACATAAATGGTGCGGCTTTCAAAAGTGAGGATTTTTCTTCAAATCATGA
AGGATTGCCCATTATAAAAATAAGGGAATTAAAATATGGAATAACACCTCAAACTGAATTTACAAAAAAGGAATTCGATC
AAAAATATCGAATAAACAACGGGGAAATATTATTTTCGTGGTCTGGTAGTCCAGACACCTCCATTGATATCTTTTTGTGG
ACAGGTGGAAATGGATGGCTAAATCAACACACCTTCCGAGTAATTCCTCAAGAGGCGGAAGAAAAGGAGTTTATATTTTT
CTTGCTTAAATTTTTCAAAAAAAGTTTCATAGAAATTGCAAGAAACAAGCAAACAACGGGCCTGGGTCATGTTACATCGA
AAGACCTAAAAAATATGTTTGCATCATTTCCAACTAAAAACGTCATAAAATTATTTAATGACGTTGGTGAGCCAATCGTT
AGTAAAATATTTTTCAACAGTACGGAGAATAATAATCTCTCTAAAATTCGTGATTTCCTTCTTCCCAAACTCCTCTCCGG
TGAACTATCCGTTGAAGCCGTCGAGTTCGCGGAGGAATAG

Upstream 100 bases:

>100_bases
GATAAAATGGCTGTACTCACCAGCCAGTTAAAAGAGCAGTTTGAAGAAAGCAGGAAACTGGAAGCTCAGATTAAACAGAA
TTTGGCGGGGTTGGGCTTCG

Downstream 100 bases:

>100_bases
GGGTTAAACTATGAATGAAGACCAATTAGAACAACTCTGTCTCGAATGGTTCCGAGATAATAGCTGGGATGTTTTATATG
GCCCTGACATTGCCCCCGAT

Product: type I restriction-modification system specificity subunit

Products: NA

Alternate protein names: S.HindVIIP; Type I restriction enzyme HindVIIP specificity protein; S protein [H]

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MFEKTIALNEFIILQRGFDLPASDRKNGNVPVVASTGIGGYHDEAKVEAPGVVIGRSGSIGGGQFITENFWPLNTTLWVK
DFKGHHPRYVYYLLKSIDFKQFNVGSGVPTLNRNHLSSILVSDIGINYETKIAEILGKIDDKIELNLKINYTLEAMAQAI
FKSWFVDFDPVKAKIAAIEAGEDSDGVTRAAISAISGKTDEELDQLQAEQPEHYIQLKNTAELFPSTMQESELGEIPDGW
EVKSLYDFAQYINGAAFKSEDFSSNHEGLPIIKIRELKYGITPQTEFTKKEFDQKYRINNGEILFSWSGSPDTSIDIFLW
TGGNGWLNQHTFRVIPQEAEEKEFIFFLLKFFKKSFIEIARNKQTTGLGHVTSKDLKNMFASFPTKNVIKLFNDVGEPIV
SKIFFNSTENNNLSKIRDFLLPKLLSGELSVEAVEFAEE

Sequences:

>Translated_439_residues
MFEKTIALNEFIILQRGFDLPASDRKNGNVPVVASTGIGGYHDEAKVEAPGVVIGRSGSIGGGQFITENFWPLNTTLWVK
DFKGHHPRYVYYLLKSIDFKQFNVGSGVPTLNRNHLSSILVSDIGINYETKIAEILGKIDDKIELNLKINYTLEAMAQAI
FKSWFVDFDPVKAKIAAIEAGEDSDGVTRAAISAISGKTDEELDQLQAEQPEHYIQLKNTAELFPSTMQESELGEIPDGW
EVKSLYDFAQYINGAAFKSEDFSSNHEGLPIIKIRELKYGITPQTEFTKKEFDQKYRINNGEILFSWSGSPDTSIDIFLW
TGGNGWLNQHTFRVIPQEAEEKEFIFFLLKFFKKSFIEIARNKQTTGLGHVTSKDLKNMFASFPTKNVIKLFNDVGEPIV
SKIFFNSTENNNLSKIRDFLLPKLLSGELSVEAVEFAEE
>Mature_439_residues
MFEKTIALNEFIILQRGFDLPASDRKNGNVPVVASTGIGGYHDEAKVEAPGVVIGRSGSIGGGQFITENFWPLNTTLWVK
DFKGHHPRYVYYLLKSIDFKQFNVGSGVPTLNRNHLSSILVSDIGINYETKIAEILGKIDDKIELNLKINYTLEAMAQAI
FKSWFVDFDPVKAKIAAIEAGEDSDGVTRAAISAISGKTDEELDQLQAEQPEHYIQLKNTAELFPSTMQESELGEIPDGW
EVKSLYDFAQYINGAAFKSEDFSSNHEGLPIIKIRELKYGITPQTEFTKKEFDQKYRINNGEILFSWSGSPDTSIDIFLW
TGGNGWLNQHTFRVIPQEAEEKEFIFFLLKFFKKSFIEIARNKQTTGLGHVTSKDLKNMFASFPTKNVIKLFNDVGEPIV
SKIFFNSTENNNLSKIRDFLLPKLLSGELSVEAVEFAEE

Specific function: The M and S subunits together form a methyltransferase (MTase) that methylates two adenine residues in complementary strands of a bipartite DNA recognition sequence. Subunit S dictates DNA sequences specificity [H]

COG id: COG0732

COG function: function code V; Restriction endonuclease S subunits

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-I restriction system S methylase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000055 [H]

Pfam domain/function: PF01420 Methylase_S [H]

EC number: NA

Molecular weight: Translated: 49429; Mature: 49429

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
0.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFEKTIALNEFIILQRGFDLPASDRKNGNVPVVASTGIGGYHDEAKVEAPGVVIGRSGSI
CCCCCEECCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCEECCCCEEEECCCCC
GGGQFITENFWPLNTTLWVKDFKGHHPRYVYYLLKSIDFKQFNVGSGVPTLNRNHLSSIL
CCCCEEECCCCCCCEEEEEECCCCCCCCEEEEHHHHCCCCEEECCCCCCCCCHHHHHHHH
VSDIGINYETKIAEILGKIDDKIELNLKINYTLEAMAQAIFKSWFVDFDPVKAKIAAIEA
HHHCCCCCHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEEEEEC
GEDSDGVTRAAISAISGKTDEELDQLQAEQPEHYIQLKNTAELFPSTMQESELGEIPDGW
CCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCHHHHCHHHHHHHHCCCCCCCC
EVKSLYDFAQYINGAAFKSEDFSSNHEGLPIIKIRELKYGITPQTEFTKKEFDQKYRINN
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHEECCC
GEILFSWSGSPDTSIDIFLWTGGNGWLNQHTFRVIPQEAEEKEFIFFLLKFFKKSFIEIA
CEEEEEECCCCCCEEEEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
RNKQTTGLGHVTSKDLKNMFASFPTKNVIKLFNDVGEPIVSKIFFNSTENNNLSKIRDFL
CCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHCCCCCCCCHHHHHHHH
LPKLLSGELSVEAVEFAEE
HHHHHCCCCCEEHHHHCCC
>Mature Secondary Structure
MFEKTIALNEFIILQRGFDLPASDRKNGNVPVVASTGIGGYHDEAKVEAPGVVIGRSGSI
CCCCCEECCEEEEEEECCCCCCCCCCCCCEEEEEECCCCCCCCCCEECCCCEEEECCCCC
GGGQFITENFWPLNTTLWVKDFKGHHPRYVYYLLKSIDFKQFNVGSGVPTLNRNHLSSIL
CCCCEEECCCCCCCEEEEEECCCCCCCCEEEEHHHHCCCCEEECCCCCCCCCHHHHHHHH
VSDIGINYETKIAEILGKIDDKIELNLKINYTLEAMAQAIFKSWFVDFDPVKAKIAAIEA
HHHCCCCCHHHHHHHHHCCCCEEEEEEEEECCHHHHHHHHHHHHCCCCCCCEEEEEEEEC
GEDSDGVTRAAISAISGKTDEELDQLQAEQPEHYIQLKNTAELFPSTMQESELGEIPDGW
CCCCCCHHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCHHHHCHHHHHHHHCCCCCCCC
EVKSLYDFAQYINGAAFKSEDFSSNHEGLPIIKIRELKYGITPQTEFTKKEFDQKYRINN
CHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCHHHHHHHHHHEECCC
GEILFSWSGSPDTSIDIFLWTGGNGWLNQHTFRVIPQEAEEKEFIFFLLKFFKKSFIEIA
CEEEEEECCCCCCEEEEEEEECCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHH
RNKQTTGLGHVTSKDLKNMFASFPTKNVIKLFNDVGEPIVSKIFFNSTENNNLSKIRDFL
CCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHCCCCCCCCHHHHHHHH
LPKLLSGELSVEAVEFAEE
HHHHHCCCCCEEHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]