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The map label for this gene is opuCB [H]

Identifier: 21226397

GI number: 21226397

Start: 395574

End: 396194

Strand: Reverse

Name: opuCB [H]

Synonym: MM_0295

Alternate gene names: 21226397

Gene position: 396194-395574 (Counterclockwise)

Preceding gene: 21226398

Following gene: 21226396

Centisome position: 9.67

GC content: 45.41

Gene sequence:

>621_bases
ATGGTCATAACTGCAGAAATTCTTGAGGCAACGCTTGAACACCTTTTCCTTGCTTATACGGCTCTTCTTGTCGGAGCCCT
TGTGTCCGTTCCTCTGATATTCCTGTCCCTCTATAATGCAAAACTTGCTTCTCTCGTAATGAGGTTTTCCAACCTTGTTC
AGGCAGTTCCCAGCTTTGCGGTCGTGGCTGTGGTTGTGCCTTTAATCGGGATTGGTTTTTTTCCAGCTGTTATAGCCATA
ATGTTAAGGGTATTGCTCCCCATAGTCAAAAATACATACATAGGCCTTTTCAACGTGGACCCTGCCCTGCTGGACTCCGC
AAAAGGCATAGGGATGACCGATTTTCAGGTTCTCAGATATGTAAGGCTCCCAAATGCTTATCCAGCCATCTTTGCGGGCA
TAAAGTTTGCAGCTATCCTTGCCAACAGCATTGCGGTCCTTACAGCCCTTATAGGTGGTGGGGGCCTGGGGTCCATGATT
TTCGAAGGACTTACAAACTTTAATACCAGCAAAATACTTGCAGGGACCCTCCCTGTCATACTCATAGCCCTTTTCCTTGA
CTTTTTCTTTTCAGCACTGGAAAAACGCTTAACTCCGGAATATCTTAAAAAATCAGGTTAA

Upstream 100 bases:

>100_bases
GCACAATCCTTGTTACGGGTGCCTGGGTGGGGCTTCTTGCAGTGCTTCTGGACGGAATAGCAGGTATAATAGAAAAAATT
CTTAAAGCGAGGTACGGGAC

Downstream 100 bases:

>100_bases
AATAAAAACCGGATGTTTTATGAATCCTTTCATAACAGGCTAAATTTATATCTCATTCTTTTAAAATGGAGTTCCGGGAA
GAAACTTTTCGGGAGCTTCC

Product: glycine betaine transport system, permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MVITAEILEATLEHLFLAYTALLVGALVSVPLIFLSLYNAKLASLVMRFSNLVQAVPSFAVVAVVVPLIGIGFFPAVIAI
MLRVLLPIVKNTYIGLFNVDPALLDSAKGIGMTDFQVLRYVRLPNAYPAIFAGIKFAAILANSIAVLTALIGGGGLGSMI
FEGLTNFNTSKILAGTLPVILIALFLDFFFSALEKRLTPEYLKKSG

Sequences:

>Translated_206_residues
MVITAEILEATLEHLFLAYTALLVGALVSVPLIFLSLYNAKLASLVMRFSNLVQAVPSFAVVAVVVPLIGIGFFPAVIAI
MLRVLLPIVKNTYIGLFNVDPALLDSAKGIGMTDFQVLRYVRLPNAYPAIFAGIKFAAILANSIAVLTALIGGGGLGSMI
FEGLTNFNTSKILAGTLPVILIALFLDFFFSALEKRLTPEYLKKSG
>Mature_206_residues
MVITAEILEATLEHLFLAYTALLVGALVSVPLIFLSLYNAKLASLVMRFSNLVQAVPSFAVVAVVVPLIGIGFFPAVIAI
MLRVLLPIVKNTYIGLFNVDPALLDSAKGIGMTDFQVLRYVRLPNAYPAIFAGIKFAAILANSIAVLTALIGGGGLGSMI
FEGLTNFNTSKILAGTLPVILIALFLDFFFSALEKRLTPEYLKKSG

Specific function: Involved in a high affinity multicomponent binding- protein-dependent transport system for glycine betaine, carnitine and choline; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG1174

COG function: function code E; ABC-type proline/glycine betaine transport systems, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788449, Length=161, Percent_Identity=36.6459627329193, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1788451, Length=201, Percent_Identity=30.8457711442786, Blast_Score=95, Evalue=3e-21,
Organism=Escherichia coli, GI1789033, Length=169, Percent_Identity=27.810650887574, Blast_Score=77, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 22022; Mature: 22022

Theoretical pI: Translated: 9.64; Mature: 9.64

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVITAEILEATLEHLFLAYTALLVGALVSVPLIFLSLYNAKLASLVMRFSNLVQAVPSFA
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVAVVVPLIGIGFFPAVIAIMLRVLLPIVKNTYIGLFNVDPALLDSAKGIGMTDFQVLRY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHCCCCCCCHHHHHHHH
VRLPNAYPAIFAGIKFAAILANSIAVLTALIGGGGLGSMIFEGLTNFNTSKILAGTLPVI
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
LIALFLDFFFSALEKRLTPEYLKKSG
HHHHHHHHHHHHHHHHCCHHHHHCCC
>Mature Secondary Structure
MVITAEILEATLEHLFLAYTALLVGALVSVPLIFLSLYNAKLASLVMRFSNLVQAVPSFA
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VVAVVVPLIGIGFFPAVIAIMLRVLLPIVKNTYIGLFNVDPALLDSAKGIGMTDFQVLRY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCHHHHHCCCCCCCHHHHHHHH
VRLPNAYPAIFAGIKFAAILANSIAVLTALIGGGGLGSMIFEGLTNFNTSKILAGTLPVI
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHH
LIALFLDFFFSALEKRLTPEYLKKSG
HHHHHHHHHHHHHHHHCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10216873; 9384377 [H]