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The map label for this gene is mtxH [H]

Identifier: 21226358

GI number: 21226358

Start: 341401

End: 342333

Strand: Direct

Name: mtxH [H]

Synonym: MM_0256

Alternate gene names: 21226358

Gene position: 341401-342333 (Clockwise)

Preceding gene: 21226357

Following gene: 21226359

Centisome position: 8.33

GC content: 48.12

Gene sequence:

>933_bases
ATGTTTAAGTTCCAGAAAGAGCAGGAAATTGCCAATATTGCAGGAATAAAAGTGGGCGGACAACCTGGAGAACTCCCTAC
CGTACTTGCAGGGACCATATTTTACAACAGGCACGAGATTGTCGAAGACGCCGCAAAAGGTCTTTTTGACAGGGATGCTG
CCGAAAAACTCGTAAATCTACAGGAGTCGGGTTCGGATACTACCGGAAACCCTCATATGGTTCACATCTTTGGCACAACC
GCAGAGAGTATCACGCGTTATATTGATTTTATTGCAGAGGTTTCGGATTCTCCTTTTCTCATAGATTCTCCCGAAGGGCC
TGTACGTGCGCATGCTGCCGGATACGTGAGTGAGATCGGGCTTGCGGACAGGGCAGTATATAACTCCATAAATATGAGCA
TAAACACATCGGAAATGAAAGCCCTTGAACAATCCGACATAGACAGTTCCATTATCCTGGGCTTCAATGCCAAAGACTCC
TCCCTTCAGGGCAGAATGGAAATGCTCGAGACAGGTGCAGGACTGTTAGAAGAAGGCCTTCTCTCAATTGCAGATAGGTG
CGGGATAGTAAACAAACTTATAGACCCGAGCATAACTCCCATGGGAAACGGAGCCGGAATAGCCCTCAGAATGACGATTG
CCGCAAAAGCAAAATGGGGCCATCCCACAGGCTCAGGAATCCATAACGCCCCCTCGGCCTGGAATTGGCTGAACCGCCAG
AAAGAAAAAGACCCTGTCCTGTATAAGATCTGCGACATAGGCTCTACCTGCCTCCAGCAGGCTGCAGCCGGAGATTTCAT
CCTCTACGGCCCTATAGAATATGCAGAATACGTTTTCCCCATGGCTGCAATGAGTGATATTATGATTGCCGAAGCCGTAG
CCGACCTTGATATAGAGCCAGTAGAAAGGCACCCTATTAACTTTCTCGTTTAA

Upstream 100 bases:

>100_bases
TAAACGTCAATAAATTTAGAACTTCAATGATAAGCCTTAATGAATTTAAAACTTCAATGATTTTTTATTTTTTATAAACG
TGGATTTCGAGGGTGCAAAA

Downstream 100 bases:

>100_bases
TTTATTAAAATACGGATTGATATCCAGAACGCAGTTTAATCCGCCCCTGAATCGAAGCCTGGAATCCTGAGTGAAAATAA
GTTTCTTTTCCCGGGAAACC

Product: putative methyltransferase

Products: 5,6,7,8-tetrahydromethanopterin; 2-(methylthio)ethanesulfonate

Alternate protein names: NA

Number of amino acids: Translated: 310; Mature: 310

Protein sequence:

>310_residues
MFKFQKEQEIANIAGIKVGGQPGELPTVLAGTIFYNRHEIVEDAAKGLFDRDAAEKLVNLQESGSDTTGNPHMVHIFGTT
AESITRYIDFIAEVSDSPFLIDSPEGPVRAHAAGYVSEIGLADRAVYNSINMSINTSEMKALEQSDIDSSIILGFNAKDS
SLQGRMEMLETGAGLLEEGLLSIADRCGIVNKLIDPSITPMGNGAGIALRMTIAAKAKWGHPTGSGIHNAPSAWNWLNRQ
KEKDPVLYKICDIGSTCLQQAAAGDFILYGPIEYAEYVFPMAAMSDIMIAEAVADLDIEPVERHPINFLV

Sequences:

>Translated_310_residues
MFKFQKEQEIANIAGIKVGGQPGELPTVLAGTIFYNRHEIVEDAAKGLFDRDAAEKLVNLQESGSDTTGNPHMVHIFGTT
AESITRYIDFIAEVSDSPFLIDSPEGPVRAHAAGYVSEIGLADRAVYNSINMSINTSEMKALEQSDIDSSIILGFNAKDS
SLQGRMEMLETGAGLLEEGLLSIADRCGIVNKLIDPSITPMGNGAGIALRMTIAAKAKWGHPTGSGIHNAPSAWNWLNRQ
KEKDPVLYKICDIGSTCLQQAAAGDFILYGPIEYAEYVFPMAAMSDIMIAEAVADLDIEPVERHPINFLV
>Mature_310_residues
MFKFQKEQEIANIAGIKVGGQPGELPTVLAGTIFYNRHEIVEDAAKGLFDRDAAEKLVNLQESGSDTTGNPHMVHIFGTT
AESITRYIDFIAEVSDSPFLIDSPEGPVRAHAAGYVSEIGLADRAVYNSINMSINTSEMKALEQSDIDSSIILGFNAKDS
SLQGRMEMLETGAGLLEEGLLSIADRCGIVNKLIDPSITPMGNGAGIALRMTIAAKAKWGHPTGSGIHNAPSAWNWLNRQ
KEKDPVLYKICDIGSTCLQQAAAGDFILYGPIEYAEYVFPMAAMSDIMIAEAVADLDIEPVERHPINFLV

Specific function: Unknown

COG id: COG1962

COG function: function code H; Tetrahydromethanopterin S-methyltransferase, subunit H

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mtrH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011005
- InterPro:   IPR002856
- ProDom:   PD009948 [H]

Pfam domain/function: PF02007 MtrH [H]

EC number: 2.1.1.86

Molecular weight: Translated: 33503; Mature: 33503

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKFQKEQEIANIAGIKVGGQPGELPTVLAGTIFYNRHEIVEDAAKGLFDRDAAEKLVNL
CCCCCHHHHHHHHHCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHCHHHHHHHHHH
QESGSDTTGNPHMVHIFGTTAESITRYIDFIAEVSDSPFLIDSPEGPVRAHAAGYVSEIG
HHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHC
LADRAVYNSINMSINTSEMKALEQSDIDSSIILGFNAKDSSLQGRMEMLETGAGLLEEGL
HHHHHHHHHCCCEEEHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCHHHHHHHH
LSIADRCGIVNKLIDPSITPMGNGAGIALRMTIAAKAKWGHPTGSGIHNAPSAWNWLNRQ
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHC
KEKDPVLYKICDIGSTCLQQAAAGDFILYGPIEYAEYVFPMAAMSDIMIAEAVADLDIEP
CCCCCEEEEEHHCCHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VERHPINFLV
CCCCCCCCCC
>Mature Secondary Structure
MFKFQKEQEIANIAGIKVGGQPGELPTVLAGTIFYNRHEIVEDAAKGLFDRDAAEKLVNL
CCCCCHHHHHHHHHCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCHHCHHHHHHHHHH
QESGSDTTGNPHMVHIFGTTAESITRYIDFIAEVSDSPFLIDSPEGPVRAHAAGYVSEIG
HHCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHC
LADRAVYNSINMSINTSEMKALEQSDIDSSIILGFNAKDSSLQGRMEMLETGAGLLEEGL
HHHHHHHHHCCCEEEHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHHHHHCHHHHHHHH
LSIADRCGIVNKLIDPSITPMGNGAGIALRMTIAAKAKWGHPTGSGIHNAPSAWNWLNRQ
HHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEECCCCCCCCCCCCCCCHHHHHHHHC
KEKDPVLYKICDIGSTCLQQAAAGDFILYGPIEYAEYVFPMAAMSDIMIAEAVADLDIEP
CCCCCEEEEEHHCCHHHHHHHCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
VERHPINFLV
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-methyl-5,6,7,8-tetrahydromethanopterin; 2-mercaptoethanesulfonate

Specific reaction: 5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate = 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]