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The map label for this gene is mtxA

Identifier: 21226357

GI number: 21226357

Start: 340711

End: 341229

Strand: Direct

Name: mtxA

Synonym: MM_0255

Alternate gene names: 21226357

Gene position: 340711-341229 (Clockwise)

Preceding gene: 21226356

Following gene: 21226358

Centisome position: 8.32

GC content: 47.01

Gene sequence:

>519_bases
GTGGTAACTCTTGCAAGCCACCTTGATGCCTGCCCTGATGCTGCTATCTGGGGCAGTTCAAAAACCGAAAACCTGGGAGT
AGAAAAGATAATAGTAAATGTAATTTCAAACTCCAATATCAGGTACGTCCTGGTCTGCGGAACCGAGTCAAGAGGCCACC
TGGCAGGGCATTCTCTCCTCGCAATCCATGCAAACGGAATTGATGAACAGGGCAGGATTACCGGTTCACAGGGAGCAATT
CCCTTTATAGAAAACATATCCGGAACTGCAGTCGAACGCTTCCAGCAGCAGGTTACAGTTCTCAATAGAATTGGGCTGAA
TGACCCTGAAGAGATCAGGAGGATTGTTGAGGACTACAGGGATAAAGGAGAAGCGTACCCTGAAGAGCCCATGCTCGTCT
GCGCTCCTAAAAAAAGGCAGACTTCTTTTGCAGTCCCCACTTCAGGAGATGTAATAATTTCAGGGGAATTCGTAATGGAT
TCAAAAGCAGGAATAATCTATACTGCGGAAAGCCTCTGA

Upstream 100 bases:

>100_bases
ACAAGGAAAGAAAAAAGGTGATTCACTGAAGCTTATCGCAGAAAACTGGCCCCCAGTAAAAGGGGACTATGTTACAGGAA
AACCCGATTCAAGAATTGCA

Downstream 100 bases:

>100_bases
TCTTTTGAAAAAATAATGGATAAAGAGAAGTCCCGGGTCAATAAAGATGAATTCTAAATCTCAATAAATTTTAAACGTCA
ATAAATTTAGAACTTCAATG

Product: methyltransferase

Products: 5,6,7,8-tetrahydromethanopterin; 2-(methylthio)ethanesulfonate

Alternate protein names: NA

Number of amino acids: Translated: 172; Mature: 172

Protein sequence:

>172_residues
MVTLASHLDACPDAAIWGSSKTENLGVEKIIVNVISNSNIRYVLVCGTESRGHLAGHSLLAIHANGIDEQGRITGSQGAI
PFIENISGTAVERFQQQVTVLNRIGLNDPEEIRRIVEDYRDKGEAYPEEPMLVCAPKKRQTSFAVPTSGDVIISGEFVMD
SKAGIIYTAESL

Sequences:

>Translated_172_residues
MVTLASHLDACPDAAIWGSSKTENLGVEKIIVNVISNSNIRYVLVCGTESRGHLAGHSLLAIHANGIDEQGRITGSQGAI
PFIENISGTAVERFQQQVTVLNRIGLNDPEEIRRIVEDYRDKGEAYPEEPMLVCAPKKRQTSFAVPTSGDVIISGEFVMD
SKAGIIYTAESL
>Mature_172_residues
MVTLASHLDACPDAAIWGSSKTENLGVEKIIVNVISNSNIRYVLVCGTESRGHLAGHSLLAIHANGIDEQGRITGSQGAI
PFIENISGTAVERFQQQVTVLNRIGLNDPEEIRRIVEDYRDKGEAYPEEPMLVCAPKKRQTSFAVPTSGDVIISGEFVMD
SKAGIIYTAESL

Specific function: Unknown

COG id: COG4063

COG function: function code H; Tetrahydromethanopterin S-methyltransferase, subunit A

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MtrA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTXA_METMA (Q8Q082)

Other databases:

- EMBL:   AE008384
- RefSeq:   NP_632279.1
- GeneID:   1478597
- GenomeReviews:   AE008384_GR
- KEGG:   mma:MM_0255
- NMPDR:   fig|192952.1.peg.255
- HOGENOM:   HBG542039
- OMA:   LLAIHAN
- ProtClustDB:   PRK14053
- BioCyc:   MMAZ192952:MM0255-MONOMER
- InterPro:   IPR013340

Pfam domain/function: PF04208 MtrA

EC number: 2.1.1.86

Molecular weight: Translated: 18611; Mature: 18611

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLASHLDACPDAAIWGSSKTENLGVEKIIVNVISNSNIRYVLVCGTESRGHLAGHSLL
CEECCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEE
AIHANGIDEQGRITGSQGAIPFIENISGTAVERFQQQVTVLNRIGLNDPEEIRRIVEDYR
EEEECCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
DKGEAYPEEPMLVCAPKKRQTSFAVPTSGDVIISGEFVMDSKAGIIYTAESL
HCCCCCCCCCEEEECCCCCCCEEECCCCCCEEEECCEEEECCCCEEEEECCC
>Mature Secondary Structure
MVTLASHLDACPDAAIWGSSKTENLGVEKIIVNVISNSNIRYVLVCGTESRGHLAGHSLL
CEECCCCCCCCCCCEECCCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEE
AIHANGIDEQGRITGSQGAIPFIENISGTAVERFQQQVTVLNRIGLNDPEEIRRIVEDYR
EEEECCCCCCCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
DKGEAYPEEPMLVCAPKKRQTSFAVPTSGDVIISGEFVMDSKAGIIYTAESL
HCCCCCCCCCEEEECCCCCCCEEECCCCCCEEEECCEEEECCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 5-methyl-5,6,7,8-tetrahydromethanopterin; 2-mercaptoethanesulfonate

Specific reaction: 5-methyl-5,6,7,8-tetrahydromethanopterin + 2-mercaptoethanesulfonate = 5,6,7,8-tetrahydromethanopterin + 2-(methylthio)ethanesulfonate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12125824