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The map label for this gene is 21226313

Identifier: 21226313

GI number: 21226313

Start: 286021

End: 288195

Strand: Direct

Name: 21226313

Synonym: MM_0211

Alternate gene names: NA

Gene position: 286021-288195 (Clockwise)

Preceding gene: 21226308

Following gene: 21226321

Centisome position: 6.98

GC content: 44.14

Gene sequence:

>2175_bases
ATGATAATCTTATTTTCGTCTCTGTCCATCAGCCCGAACCTCGCAGCCGGAAGTGCCGAAAACTTAGAGCCGCCCCTGAA
CAGCACATCAATTTCAGACACTGCAATTGAAGAAGCACCTCTGAACCCGGAATTTCTGAACCCCGGAAAATCAGAATCAT
TAGAGCCTGTTTCATCCTGTGACTACGGGCATGCCTCAGGCCCGGGGTATACCCCCCCTCCGGTAAATATACCAGCACTC
TCACAGAAAGGGGGAAAGCTTCTGCTCAGGGCGCAGGGTTCGGAACTCCCTTCAACGTATGATTTGCGTGAACAGGGAAG
GATTACATCTGTAAAAAACCAGGGAGACACCGGAAGCTGCTGGGCTTTTTCAAGCCTTGCATCCCTTGAATCTTATATTC
TGGGGACAGAGGGAAATAGTAGAGACTTTTCCGAAAATAACATGAAAAATCTTGTCACAAGGTACTATTCCGATGGTTTT
GACCTGACTCCCGATAACGGCGGAAATTCTTTCATAGCCATGGCATATCTTACCCGCTGGTCAGGGCCTGTAAATGAATC
TGCAGACCCATATAATGAAAACTCGGTCAATTCCCCTGCAGGGCTTCCTGTGCAGAAACATGTTCAGGAAGTAGTTGTAC
TGCCTGAGAGAACCGGGCCTCTGGATAACGAGTTAATTAAAAGGGCACTTATGGATAAGGGAGCTGTGTTTTCTACAATA
TGCTGGAATTTGCCGGATTATCATGATAAGAATTACACCTACAGATACACCGGATCAAATTCTGCAAATCATGCGATAAC
CATAGTAGGCTGGGATGATTCCTTTGACAGACACAGGTTCAAACAGGTTCCATCAGGAAATGGAGCTTTTATTGTAAAGA
ACAGCTGGGGAGAATCCTGGGGAGAAGATGGATATTTCTATATTTCCTATTATGATACCAGTATTGGATACAGAGAAAAT
GCAGTCTTTACGGCTTCGGAAAAAGAGAATTTTGACTATATCTACCAGTATGACCCCCTCGGCTGGATAACCCAAATAGG
TTATTCCGAATTAACCGCCTGGGGAAGCAATGTTTTTACCACGGAAAGAAATGAAAAACTGGAAGCTATAGGGTTCTATA
CTACAGATCTCAATACGGCTTATGAGATCTATGTATACAAAAACCCGACAAACGGCCCGATTAATTCATTAAAAAATTAT
GCTGTAAAGGAAAGCGGTACCTGCTCATTTCCCGGATATCACACCCACATACTTAATTCTCCTGTAAACCTGATTCCGGG
AGAGAAATTTTCTGTTGTTATAAAGTGCAGGAATCCTTCTTACGTATACCCTCTTGCAGTTGAGAAACAGTACCTCGATT
ACAGCAGTAAGGCACAGGCAAATCCCGGGGAGAGCTATGTAAGCCGGGACGGGAACAGCTGGAAGGACCTGACATCAGTT
GTCGAATACGCGGAAACAAACCTCTGTATAAAGGCGTTTACAACTGTCAATGAGCTGCCAGAAGCTGGATTCTCATCAAA
CATTACCAGCTGGGTTTCTCCTCTTACAGTCCAGTTCACTGACCTTTCAACAGGTGCCCTGTCATGGGAATGGGATTTTA
ACGGGGACGGGATTACAGACTCAACAACCAAAAACCCTGTCTGCACCTACACATCTTACGGAAATTATACCGTTTCATTA
AATGCAAGCAACAGGAAAGGTTTTGACACCGAAATAAAACCCGGTTATATAACAGTAAGCCCTCTATCAATTATCTCTTC
AAGTCCCGGAGGAAATATCACTACCTATGAAGGGGAAAGGCAGGAATTCAATATCAGCACAAATCATAACACCAGTGCAA
ACTGGTATGTTAACGGAACGAAAAAACTTACCGAAACCGGTGTTAAAAGCAGTTCATATTCGGAAAGTACTCTGTTTCCA
GGAACATATGATGTTACCGTGCTTGTCATAACAGGAAACGAAAATGTTATGCTTACCTGGAACTGGACAGTCGTTGACTG
GAACCCATGGGACGATTTGACCTCCCTGGATGGGAAAAACATAAGCACGGAAGAACTCCAGGAAGCAATACACATCTATA
AAAACGGCCTACCTATCCCAGGGACAGAAACCAAGCTAACAGACGAAGGACTCATAAAACTGATAAGGCTCTGGAAAGAA
GGAGCTGCAAATTGA

Upstream 100 bases:

>100_bases
CCTGCTATGCCAGTTACTCCATGCTGTCTTTCATCTAACTGAAAACCAATCCACCCGAGGCCGAGAATTTTTGAAAAAGA
TAAATTCCTTTTTGCTTTCA

Downstream 100 bases:

>100_bases
AAAGAGAATCAGCAAGAGGGAAACTGTAAAATGAGAGGGAAACTGTAAAATGTTTCCCGTTAATTTTTTGTTTTTATTCC
ACGCCTTCAATTGCTCAATT

Product: cysteine proteinase

Products: NA

Alternate protein names: Peptidase C1A Papain; Adhesin-Like Protein With Cysteine Protease Domain; Cysteine Proteinase; 5-Nucleotidase/2' 3'-Cyclic Phosphodiesterase-Like Protein; PKD Domain-Containing Protein; Adhesin-Like Protein; Surface Layer Protein; Surface Layer Protein B; Cell Surface-Associated Cysteine Protease; PKD Domain Containing Protein; Preprotein Translocase Subunit SecD-Like Protein; Papain Family Protease; Surface Antigen Gene; Peptidase S8 And; Cell Surface Glycoprotein; KP-43 Peptidase; Asn/Thr-Rich Large Protein Family Protein; Cysteine Protease C1 Family Protein; Papain Family Cysteine Protease; PKD Repeat-Containing Protein; Cysteine Peptidase

Number of amino acids: Translated: 724; Mature: 724

Protein sequence:

>724_residues
MIILFSSLSISPNLAAGSAENLEPPLNSTSISDTAIEEAPLNPEFLNPGKSESLEPVSSCDYGHASGPGYTPPPVNIPAL
SQKGGKLLLRAQGSELPSTYDLREQGRITSVKNQGDTGSCWAFSSLASLESYILGTEGNSRDFSENNMKNLVTRYYSDGF
DLTPDNGGNSFIAMAYLTRWSGPVNESADPYNENSVNSPAGLPVQKHVQEVVVLPERTGPLDNELIKRALMDKGAVFSTI
CWNLPDYHDKNYTYRYTGSNSANHAITIVGWDDSFDRHRFKQVPSGNGAFIVKNSWGESWGEDGYFYISYYDTSIGYREN
AVFTASEKENFDYIYQYDPLGWITQIGYSELTAWGSNVFTTERNEKLEAIGFYTTDLNTAYEIYVYKNPTNGPINSLKNY
AVKESGTCSFPGYHTHILNSPVNLIPGEKFSVVIKCRNPSYVYPLAVEKQYLDYSSKAQANPGESYVSRDGNSWKDLTSV
VEYAETNLCIKAFTTVNELPEAGFSSNITSWVSPLTVQFTDLSTGALSWEWDFNGDGITDSTTKNPVCTYTSYGNYTVSL
NASNRKGFDTEIKPGYITVSPLSIISSSPGGNITTYEGERQEFNISTNHNTSANWYVNGTKKLTETGVKSSSYSESTLFP
GTYDVTVLVITGNENVMLTWNWTVVDWNPWDDLTSLDGKNISTEELQEAIHIYKNGLPIPGTETKLTDEGLIKLIRLWKE
GAAN

Sequences:

>Translated_724_residues
MIILFSSLSISPNLAAGSAENLEPPLNSTSISDTAIEEAPLNPEFLNPGKSESLEPVSSCDYGHASGPGYTPPPVNIPAL
SQKGGKLLLRAQGSELPSTYDLREQGRITSVKNQGDTGSCWAFSSLASLESYILGTEGNSRDFSENNMKNLVTRYYSDGF
DLTPDNGGNSFIAMAYLTRWSGPVNESADPYNENSVNSPAGLPVQKHVQEVVVLPERTGPLDNELIKRALMDKGAVFSTI
CWNLPDYHDKNYTYRYTGSNSANHAITIVGWDDSFDRHRFKQVPSGNGAFIVKNSWGESWGEDGYFYISYYDTSIGYREN
AVFTASEKENFDYIYQYDPLGWITQIGYSELTAWGSNVFTTERNEKLEAIGFYTTDLNTAYEIYVYKNPTNGPINSLKNY
AVKESGTCSFPGYHTHILNSPVNLIPGEKFSVVIKCRNPSYVYPLAVEKQYLDYSSKAQANPGESYVSRDGNSWKDLTSV
VEYAETNLCIKAFTTVNELPEAGFSSNITSWVSPLTVQFTDLSTGALSWEWDFNGDGITDSTTKNPVCTYTSYGNYTVSL
NASNRKGFDTEIKPGYITVSPLSIISSSPGGNITTYEGERQEFNISTNHNTSANWYVNGTKKLTETGVKSSSYSESTLFP
GTYDVTVLVITGNENVMLTWNWTVVDWNPWDDLTSLDGKNISTEELQEAIHIYKNGLPIPGTETKLTDEGLIKLIRLWKE
GAAN
>Mature_724_residues
MIILFSSLSISPNLAAGSAENLEPPLNSTSISDTAIEEAPLNPEFLNPGKSESLEPVSSCDYGHASGPGYTPPPVNIPAL
SQKGGKLLLRAQGSELPSTYDLREQGRITSVKNQGDTGSCWAFSSLASLESYILGTEGNSRDFSENNMKNLVTRYYSDGF
DLTPDNGGNSFIAMAYLTRWSGPVNESADPYNENSVNSPAGLPVQKHVQEVVVLPERTGPLDNELIKRALMDKGAVFSTI
CWNLPDYHDKNYTYRYTGSNSANHAITIVGWDDSFDRHRFKQVPSGNGAFIVKNSWGESWGEDGYFYISYYDTSIGYREN
AVFTASEKENFDYIYQYDPLGWITQIGYSELTAWGSNVFTTERNEKLEAIGFYTTDLNTAYEIYVYKNPTNGPINSLKNY
AVKESGTCSFPGYHTHILNSPVNLIPGEKFSVVIKCRNPSYVYPLAVEKQYLDYSSKAQANPGESYVSRDGNSWKDLTSV
VEYAETNLCIKAFTTVNELPEAGFSSNITSWVSPLTVQFTDLSTGALSWEWDFNGDGITDSTTKNPVCTYTSYGNYTVSL
NASNRKGFDTEIKPGYITVSPLSIISSSPGGNITTYEGERQEFNISTNHNTSANWYVNGTKKLTETGVKSSSYSESTLFP
GTYDVTVLVITGNENVMLTWNWTVVDWNPWDDLTSLDGKNISTEELQEAIHIYKNGLPIPGTETKLTDEGLIKLIRLWKE
GAAN

Specific function: Unknown

COG id: COG4870

COG function: function code O; Cysteine protease

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4503151, Length=220, Percent_Identity=31.8181818181818, Blast_Score=87, Evalue=7e-17,
Organism=Homo sapiens, GI4503155, Length=235, Percent_Identity=28.936170212766, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI22202619, Length=235, Percent_Identity=28.936170212766, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI23110960, Length=244, Percent_Identity=27.8688524590164, Blast_Score=72, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17563798, Length=223, Percent_Identity=28.6995515695067, Blast_Score=75, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71993922, Length=232, Percent_Identity=28.0172413793103, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115533516, Length=264, Percent_Identity=28.7878787878788, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533514, Length=264, Percent_Identity=28.7878787878788, Blast_Score=68, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24654434, Length=217, Percent_Identity=29.4930875576037, Blast_Score=84, Evalue=4e-16,
Organism=Drosophila melanogaster, GI45552699, Length=217, Percent_Identity=29.4930875576037, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24654437, Length=217, Percent_Identity=29.4930875576037, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24654439, Length=217, Percent_Identity=29.4930875576037, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI19922450, Length=217, Percent_Identity=29.4930875576037, Blast_Score=84, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24644155, Length=244, Percent_Identity=29.0983606557377, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24644153, Length=244, Percent_Identity=29.0983606557377, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 80041; Mature: 80041

Theoretical pI: Translated: 4.42; Mature: 4.42

Prosite motif: PS50093 PKD ; PS00139 THIOL_PROTEASE_CYS ; PS00639 THIOL_PROTEASE_HIS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIILFSSLSISPNLAAGSAENLEPPLNSTSISDTAIEEAPLNPEFLNPGKSESLEPVSSC
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHCCCCCCCCCCCHHCC
DYGHASGPGYTPPPVNIPALSQKGGKLLLRAQGSELPSTYDLREQGRITSVKNQGDTGSC
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHCCCEEEECCCCCCCCC
WAFSSLASLESYILGTEGNSRDFSENNMKNLVTRYYSDGFDLTPDNGGNSFIAMAYLTRW
HHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEHHC
SGPVNESADPYNENSVNSPAGLPVQKHVQEVVVLPERTGPLDNELIKRALMDKGAVFSTI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEEECCCCCCCHHHHHHHHHHCCCCEEEHH
CWNLPDYHDKNYTYRYTGSNSANHAITIVGWDDSFDRHRFKQVPSGNGAFIVKNSWGESW
HCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCEEEEECCCCCCC
GEDGYFYISYYDTSIGYRENAVFTASEKENFDYIYQYDPLGWITQIGYSELTAWGSNVFT
CCCCEEEEEEEECCCCCCCCEEEEECCCCCCCEEEEECCCHHHHHCCHHHHHHCCCCEEE
TERNEKLEAIGFYTTDLNTAYEIYVYKNPTNGPINSLKNYAVKESGTCSFPGYHTHILNS
CCCCCCEEEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCEEEEECC
PVNLIPGEKFSVVIKCRNPSYVYPLAVEKQYLDYSSKAQANPGESYVSRDGNSWKDLTSV
CCCCCCCCCEEEEEEECCCCEEEEEEECHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHHH
VEYAETNLCIKAFTTVNELPEAGFSSNITSWVSPLTVQFTDLSTGALSWEWDFNGDGITD
HHHHHCCEEEEEHHHHHHHCCCCCCCCHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCC
STTKNPVCTYTSYGNYTVSLNASNRKGFDTEIKPGYITVSPLSIISSSPGGNITTYEGER
CCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEECHHHHCCCCCCCCEEEECCCC
QEFNISTNHNTSANWYVNGTKKLTETGVKSSSYSESTLFPGTYDVTVLVITGNENVMLTW
EEEEEECCCCCCEEEEECCCHHHHHHCCCCCCCCCCEECCCCEEEEEEEEECCCCEEEEE
NWTVVDWNPWDDLTSLDGKNISTEELQEAIHIYKNGLPIPGTETKLTDEGLIKLIRLWKE
EEEEEECCCCCCHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
GAAN
CCCC
>Mature Secondary Structure
MIILFSSLSISPNLAAGSAENLEPPLNSTSISDTAIEEAPLNPEFLNPGKSESLEPVSSC
CEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCHHHCCCCCCCCCCCHHCC
DYGHASGPGYTPPPVNIPALSQKGGKLLLRAQGSELPSTYDLREQGRITSVKNQGDTGSC
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHCCCEEEECCCCCCCCC
WAFSSLASLESYILGTEGNSRDFSENNMKNLVTRYYSDGFDLTPDNGGNSFIAMAYLTRW
HHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEHHC
SGPVNESADPYNENSVNSPAGLPVQKHVQEVVVLPERTGPLDNELIKRALMDKGAVFSTI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEEECCCCCCCHHHHHHHHHHCCCCEEEHH
CWNLPDYHDKNYTYRYTGSNSANHAITIVGWDDSFDRHRFKQVPSGNGAFIVKNSWGESW
HCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCHHHHHHHCCCCCCCEEEEECCCCCCC
GEDGYFYISYYDTSIGYRENAVFTASEKENFDYIYQYDPLGWITQIGYSELTAWGSNVFT
CCCCEEEEEEEECCCCCCCCEEEEECCCCCCCEEEEECCCHHHHHCCHHHHHHCCCCEEE
TERNEKLEAIGFYTTDLNTAYEIYVYKNPTNGPINSLKNYAVKESGTCSFPGYHTHILNS
CCCCCCEEEEEEEEECCCCEEEEEEEECCCCCCHHHHHHHHCCCCCCCCCCCCEEEEECC
PVNLIPGEKFSVVIKCRNPSYVYPLAVEKQYLDYSSKAQANPGESYVSRDGNSWKDLTSV
CCCCCCCCCEEEEEEECCCCEEEEEEECHHHCCCCCCCCCCCCHHHHHCCCCCHHHHHHH
VEYAETNLCIKAFTTVNELPEAGFSSNITSWVSPLTVQFTDLSTGALSWEWDFNGDGITD
HHHHHCCEEEEEHHHHHHHCCCCCCCCHHHHCCCEEEEEEECCCCEEEEEEECCCCCCCC
STTKNPVCTYTSYGNYTVSLNASNRKGFDTEIKPGYITVSPLSIISSSPGGNITTYEGER
CCCCCCEEEEECCCCEEEEEECCCCCCCCCCCCCCEEEECHHHHCCCCCCCCEEEECCCC
QEFNISTNHNTSANWYVNGTKKLTETGVKSSSYSESTLFPGTYDVTVLVITGNENVMLTW
EEEEEECCCCCCEEEEECCCHHHHHHCCCCCCCCCCEECCCCEEEEEEEEECCCCEEEEE
NWTVVDWNPWDDLTSLDGKNISTEELQEAIHIYKNGLPIPGTETKLTDEGLIKLIRLWKE
EEEEEECCCCCCHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHH
GAAN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA