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The map label for this gene is mtaA [H]

Identifier: 21226278

GI number: 21226278

Start: 240526

End: 241545

Strand: Reverse

Name: mtaA [H]

Synonym: MM_0176

Alternate gene names: 21226278

Gene position: 241545-240526 (Counterclockwise)

Preceding gene: 21226282

Following gene: 21226274

Centisome position: 5.9

GC content: 48.33

Gene sequence:

>1020_bases
ATGGGTGATATGACACTTAAGGAGAGACTTTTAAACGCATTGGAAGGAAAGCAGGTTGACAAAGTGCCTGTTTGTTCCGT
GACTCAGACCGGGATTGTAGAATTGATGGATCAGGTGGGAGCACCCTGGCCAGAAGCTCACTCAGAACCTGAACTGATGG
CAAAGCTGGCGATTGCAAATTATGAGGTCAGCGGGCTCGAAGCTGTGAGGGTTCCATACTGCCTGACAGTGCTTGCAGAA
GCAATGGGATGTGAGGTCAATATGGGGACAAAAAACAGGCAGCCTTCTGTCACAGCTCACCCTTACCCCAAAGATCTCGA
AGGTATGGAAATGCCTGAGAACCTGATTGATAAGGGCAGGATCCAGGCTGTCCTGGGCTCTATTAAAATCATCAGAGAAA
AGGTAGGACCTGATGTGCCTATTATCGGCGGTATGGAAGGTCCGGTTACCCTTGCCTCCGACCTCTCAAGTGTAAAGACT
TTTATGAAATGGTCTCTGAAAAAACCCGATCTTTTTGAGCAGGTACTTGATTTTGCTACCGAAGCCACAATAGCCTACGC
AAACTCTATGGCTCTTGCAGGAGCAGACGTTGTTGCCATTGCGGACCCTGTTGCATCTCCTGACCTGATGAGTCCTGACT
CCTTTAAAAATATACTTCAATCAAGACTCCAGAGGTTTTCCTCAAATGTGAACTCGGTCACAGTCCTGCACGTCTGCGGC
AATGTAAATCCTATCCTTGACTATATGGCAGACTGTGGTTTCGAAGGTCTGAGTGTTGAAGAAAAAATAGGGAGCGTAAA
GAAAGCCAAAGAAATACTCGGGGACAGAACCAGGCTCGTAGGAAACATTTCAAGCCCGTTCACTTTGCTTCCGGGCCCGG
TTGACAAAATAAAAACCGAAGCCAGGCAGGCTCTTGATGACGGAGTTGACGTGCTGGCACCGGGATGTGGAATTGCGCCC
ATGACCCCTGTTTCTCACATTAAAGCTATGGTAGAAGCCAGGGACGAGTATTACGCCTGA

Upstream 100 bases:

>100_bases
ACGGTTAAAAACTGGACCGGAAAATTTCTTAAATATATTTCTTGACCGTAGCTGGACAGAGGCAGAATAAATCTCGAATC
ATTTCAACGGGGAGATTACC

Downstream 100 bases:

>100_bases
TTAATTGATATATATCTCCACTTAATTTTTAATTTCATTTTTTAGTCGAATGTGTTTTTAAAAATTTTTCTTTTTGTATC
TTTTTTATTTTTATTATTTC

Product: methylcobalamin:coenzyme M methyltransferase

Products: NA

Alternate protein names: MT2-A; Methylcobamide:CoM methyltransferase II isozyme A [H]

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MGDMTLKERLLNALEGKQVDKVPVCSVTQTGIVELMDQVGAPWPEAHSEPELMAKLAIANYEVSGLEAVRVPYCLTVLAE
AMGCEVNMGTKNRQPSVTAHPYPKDLEGMEMPENLIDKGRIQAVLGSIKIIREKVGPDVPIIGGMEGPVTLASDLSSVKT
FMKWSLKKPDLFEQVLDFATEATIAYANSMALAGADVVAIADPVASPDLMSPDSFKNILQSRLQRFSSNVNSVTVLHVCG
NVNPILDYMADCGFEGLSVEEKIGSVKKAKEILGDRTRLVGNISSPFTLLPGPVDKIKTEARQALDDGVDVLAPGCGIAP
MTPVSHIKAMVEARDEYYA

Sequences:

>Translated_339_residues
MGDMTLKERLLNALEGKQVDKVPVCSVTQTGIVELMDQVGAPWPEAHSEPELMAKLAIANYEVSGLEAVRVPYCLTVLAE
AMGCEVNMGTKNRQPSVTAHPYPKDLEGMEMPENLIDKGRIQAVLGSIKIIREKVGPDVPIIGGMEGPVTLASDLSSVKT
FMKWSLKKPDLFEQVLDFATEATIAYANSMALAGADVVAIADPVASPDLMSPDSFKNILQSRLQRFSSNVNSVTVLHVCG
NVNPILDYMADCGFEGLSVEEKIGSVKKAKEILGDRTRLVGNISSPFTLLPGPVDKIKTEARQALDDGVDVLAPGCGIAP
MTPVSHIKAMVEARDEYYA
>Mature_338_residues
GDMTLKERLLNALEGKQVDKVPVCSVTQTGIVELMDQVGAPWPEAHSEPELMAKLAIANYEVSGLEAVRVPYCLTVLAEA
MGCEVNMGTKNRQPSVTAHPYPKDLEGMEMPENLIDKGRIQAVLGSIKIIREKVGPDVPIIGGMEGPVTLASDLSSVKTF
MKWSLKKPDLFEQVLDFATEATIAYANSMALAGADVVAIADPVASPDLMSPDSFKNILQSRLQRFSSNVNSVTVLHVCGN
VNPILDYMADCGFEGLSVEEKIGSVKKAKEILGDRTRLVGNISSPFTLLPGPVDKIKTEARQALDDGVDVLAPGCGIAPM
TPVSHIKAMVEARDEYYA

Specific function: Catalyzes the transfer of the methyl group from the methylated corrinoid cofactor of mtmC, mtbC and mttC to coenzyme M [H]

COG id: COG0407

COG function: function code H; Uroporphyrinogen-III decarboxylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uroporphyrinogen decarboxylase family. MtbA/mtaA subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006360
- InterPro:   IPR000257 [H]

Pfam domain/function: PF01208 URO-D [H]

EC number: NA

Molecular weight: Translated: 36471; Mature: 36339

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDMTLKERLLNALEGKQVDKVPVCSVTQTGIVELMDQVGAPWPEAHSEPELMAKLAIAN
CCCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHC
YEVSGLEAVRVPYCLTVLAEAMGCEVNMGTKNRQPSVTAHPYPKDLEGMEMPENLIDKGR
CCCCCCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
IQAVLGSIKIIREKVGPDVPIIGGMEGPVTLASDLSSVKTFMKWSLKKPDLFEQVLDFAT
HHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
EATIAYANSMALAGADVVAIADPVASPDLMSPDSFKNILQSRLQRFSSNVNSVTVLHVCG
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECC
NVNPILDYMADCGFEGLSVEEKIGSVKKAKEILGDRTRLVGNISSPFTLLPGPVDKIKTE
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEECCCCHHHHHHH
ARQALDDGVDVLAPGCGIAPMTPVSHIKAMVEARDEYYA
HHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
GDMTLKERLLNALEGKQVDKVPVCSVTQTGIVELMDQVGAPWPEAHSEPELMAKLAIAN
CCHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHC
YEVSGLEAVRVPYCLTVLAEAMGCEVNMGTKNRQPSVTAHPYPKDLEGMEMPENLIDKGR
CCCCCCHHHHHHHHHHHHHHHHCCEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
IQAVLGSIKIIREKVGPDVPIIGGMEGPVTLASDLSSVKTFMKWSLKKPDLFEQVLDFAT
HHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
EATIAYANSMALAGADVVAIADPVASPDLMSPDSFKNILQSRLQRFSSNVNSVTVLHVCG
HHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEECC
NVNPILDYMADCGFEGLSVEEKIGSVKKAKEILGDRTRLVGNISSPFTLLPGPVDKIKTE
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCEECCCCHHHHHHH
ARQALDDGVDVLAPGCGIAPMTPVSHIKAMVEARDEYYA
HHHHHHCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8702528; 9642198; 7635826; 8617801; 9006042; 9195968; 10852929 [H]