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The map label for this gene is 21226282

Identifier: 21226282

GI number: 21226282

Start: 249857

End: 250423

Strand: Reverse

Name: 21226282

Synonym: MM_0180

Alternate gene names: NA

Gene position: 250423-249857 (Counterclockwise)

Preceding gene: 161485683

Following gene: 21226278

Centisome position: 6.11

GC content: 44.44

Gene sequence:

>567_bases
TTGTATACATCCATAAATTTCTGTAAATTTTCCAGGGTTATACAAACTGATACGAAAAAAGGAATGAAGATGCCTGACAC
TGAGAAGAAACCCGCTTTGAACATCCGCGCTGCAAAAAAAGAAGATATCCCTCTTATCCTTGAGTTTATAAAAGGGATTG
CCGAATTTGAAAAACTTACTCACCTTGTTACAGCCACGGAAGAAACCCTTGAGGAATCCATGTTCGGTGAAAAGCCTTAT
TCTGAGGTTTTCTTTGCCGAGCTTGACGGAGAGCCTGCTGGTTTTACGGTCTTTTTTCACAACTTCTCTACTTTCGTGGG
AAAGCAGGGGCTCTATATCGAAGACATTTTTGTAAAGCCCGGGTTCAGGGGTAAAGGTATCGGAAAAGCAATGTTCCTGC
ACTGCATTAATCTCGCGAAAGAAAGGAACTGCGGGAGAATGGAATGGGCGGTGCTCGACTGGAATCCTGCAAGGGAATTC
TACGAATACTTCGGAGCCGGGCCTGTTGACGGCTGGCACATCTACCGCATGAGTGCGGATAAGTTCGAAAGTGCGCTTGA
AAAATAA

Upstream 100 bases:

>100_bases
TTGAAATCAATTATCTTGAAGCCAATTATTATGAAATTAATTATCTCGAAATAAATTGTTATGAAACAGACTATTATGAA
ACAGATTATTATGAAATTAA

Downstream 100 bases:

>100_bases
GTTTTAGAATTTTTTCTCCAGCTTTCCTGTATTCAGGGCGGGTATTTTAAAATTCAGGTTGTATCTTCCTGCTGGATGAA
AGAGTGGTGTTCAAGCCGTT

Product: diamine acetyltransferase

Products: CoA; N-acetyldiamine

Alternate protein names: Acetyltransferase; N-Acetyltransferase; Acetyltransferase GNAT Family; GNAT Family Acetyltransferase; Diamine N-Acetyltransferase; GCN5-Like N-Acetyltransferase; Acetyltransferase Family Protein; Acetyltransferase Protein; Diamine Acetyltransferase; Histone Acetyltransferase HPA2-Like Acetyltransferase; Acetyltransferase GNAT Family Protein; Histone Acetyltransferase HPA; N-Acetyltransferase Protein; GNAT-Family Acetyltransferase; ACETYLTRANSFERASE GCN5-Related N-Acetyltransferase; LOW QUALITY PROTEIN Acetyltransferase; Gcn5-Related N-Acetyltransferase; Sortase-Like Acyltransferase; Gnat Acetyltransferase; Argininosuccinate Synthase; Spermidine/Spermine N1-Acetyl Transferase

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MYTSINFCKFSRVIQTDTKKGMKMPDTEKKPALNIRAAKKEDIPLILEFIKGIAEFEKLTHLVTATEETLEESMFGEKPY
SEVFFAELDGEPAGFTVFFHNFSTFVGKQGLYIEDIFVKPGFRGKGIGKAMFLHCINLAKERNCGRMEWAVLDWNPAREF
YEYFGAGPVDGWHIYRMSADKFESALEK

Sequences:

>Translated_188_residues
MYTSINFCKFSRVIQTDTKKGMKMPDTEKKPALNIRAAKKEDIPLILEFIKGIAEFEKLTHLVTATEETLEESMFGEKPY
SEVFFAELDGEPAGFTVFFHNFSTFVGKQGLYIEDIFVKPGFRGKGIGKAMFLHCINLAKERNCGRMEWAVLDWNPAREF
YEYFGAGPVDGWHIYRMSADKFESALEK
>Mature_188_residues
MYTSINFCKFSRVIQTDTKKGMKMPDTEKKPALNIRAAKKEDIPLILEFIKGIAEFEKLTHLVTATEETLEESMFGEKPY
SEVFFAELDGEPAGFTVFFHNFSTFVGKQGLYIEDIFVKPGFRGKGIGKAMFLHCINLAKERNCGRMEWAVLDWNPAREF
YEYFGAGPVDGWHIYRMSADKFESALEK

Specific function: Unknown

COG id: COG0454

COG function: function code KR; Histone acetyltransferase HPA2 and related acetyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI19424126, Length=156, Percent_Identity=34.6153846153846, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI4506789, Length=158, Percent_Identity=31.6455696202532, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI17559148, Length=137, Percent_Identity=35.036496350365, Blast_Score=87, Evalue=4e-18,
Organism=Drosophila melanogaster, GI24647013, Length=161, Percent_Identity=36.6459627329193, Blast_Score=104, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24647015, Length=124, Percent_Identity=37.9032258064516, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.3.1.57

Molecular weight: Translated: 21583; Mature: 21583

Theoretical pI: Translated: 6.14; Mature: 6.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTSINFCKFSRVIQTDTKKGMKMPDTEKKPALNIRAAKKEDIPLILEFIKGIAEFEKLT
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHH
HLVTATEETLEESMFGEKPYSEVFFAELDGEPAGFTVFFHNFSTFVGKQGLYIEDIFVKP
HHHHHHHHHHHHHHCCCCCCHHEEEEECCCCCCCEEEEEECHHHHHCCCCCEEEEEEECC
GFRGKGIGKAMFLHCINLAKERNCGRMEWAVLDWNPAREFYEYFGAGPVDGWHIYRMSAD
CCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCEEEEEECHH
KFESALEK
HHHHHHCC
>Mature Secondary Structure
MYTSINFCKFSRVIQTDTKKGMKMPDTEKKPALNIRAAKKEDIPLILEFIKGIAEFEKLT
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHH
HLVTATEETLEESMFGEKPYSEVFFAELDGEPAGFTVFFHNFSTFVGKQGLYIEDIFVKP
HHHHHHHHHHHHHHCCCCCCHHEEEEECCCCCCCEEEEEECHHHHHCCCCCEEEEEEECC
GFRGKGIGKAMFLHCINLAKERNCGRMEWAVLDWNPAREFYEYFGAGPVDGWHIYRMSAD
CCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHCCCCCCCEEEEEECHH
KFESALEK
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acetyl-CoA; Alkane-alpha,omega-diamine

Specific reaction: acetyl-CoA + an alkane-alpha,omega -diamine = CoA + an N-acetyldiamine

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA