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The map label for this gene is nifU [H]

Identifier: 21226212

GI number: 21226212

Start: 136866

End: 137294

Strand: Direct

Name: nifU [H]

Synonym: MM_0110

Alternate gene names: 21226212

Gene position: 136866-137294 (Clockwise)

Preceding gene: 21226211

Following gene: 21226213

Centisome position: 3.34

GC content: 45.92

Gene sequence:

>429_bases
GTGAAAAATGAATACAAAGGACGCAAGTGGGGGAATTTTGTGTATAATAAGAAAGTAATGGACCATTTTATGAATCCGAG
AAACGTGGGGGAAATAGAAAATGCGGATGGCATCGGAGAAGCAGGAAACCCTCACGGGGACCAGATGAAGATCTTCCTGA
AAATACGGGACAACAGAATAGAAGATGTAAAGTTCAAGACTTTTGGCTGTGCAGCAGCAATAGCTTCCAGCAGCATGGCA
ACTGAAATGATAAAGGGCAAAACCCTTGAAGAAGCCTGGGAGCTTACAGATGAAGCTGTAGCCGAAGCCCTTGAAGGGCT
GCCTCCGGGAAAACTTGAATGTTCGGTAGTTTCGAGGGAAGCTACCCACAGAGCGATCAATGATTACCGCAAAAAGCAGG
GGCTTGAACCTCTGGAAGAAAAGACCTGA

Upstream 100 bases:

>100_bases
GCAAATACCGAAGAAGATGTCGATTACGTACTCGAAGTCCTGCCTCAGGTCGTGGAAAAATTAAGGGCTATATCTCCATT
CTATAAACCATCAGATGTAT

Downstream 100 bases:

>100_bases
AAAAAGATAAAGATCCTCAGGGCTAAACTCTGCATGATTACCTTTCCGAACTCTTTTAGCCCCGGATATTTCAATTGAAA
ATATGATTTAACCCATATCG

Product: NifU protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MKNEYKGRKWGNFVYNKKVMDHFMNPRNVGEIENADGIGEAGNPHGDQMKIFLKIRDNRIEDVKFKTFGCAAAIASSSMA
TEMIKGKTLEEAWELTDEAVAEALEGLPPGKLECSVVSREATHRAINDYRKKQGLEPLEEKT

Sequences:

>Translated_142_residues
MKNEYKGRKWGNFVYNKKVMDHFMNPRNVGEIENADGIGEAGNPHGDQMKIFLKIRDNRIEDVKFKTFGCAAAIASSSMA
TEMIKGKTLEEAWELTDEAVAEALEGLPPGKLECSVVSREATHRAINDYRKKQGLEPLEEKT
>Mature_142_residues
MKNEYKGRKWGNFVYNKKVMDHFMNPRNVGEIENADGIGEAGNPHGDQMKIFLKIRDNRIEDVKFKTFGCAAAIASSSMA
TEMIKGKTLEEAWELTDEAVAEALEGLPPGKLECSVVSREATHRAINDYRKKQGLEPLEEKT

Specific function: May be involved in the formation or repair of [Fe-S] clusters present in iron-sulfur proteins (Potential) [H]

COG id: COG0822

COG function: function code C; NifU homolog involved in Fe-S cluster formation

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nifU family [H]

Homologues:

Organism=Homo sapiens, GI56699456, Length=125, Percent_Identity=47.2, Blast_Score=112, Evalue=1e-25,
Organism=Homo sapiens, GI24307953, Length=124, Percent_Identity=45.1612903225806, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1788878, Length=126, Percent_Identity=48.4126984126984, Blast_Score=116, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI17543474, Length=124, Percent_Identity=48.3870967741936, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6325122, Length=126, Percent_Identity=44.4444444444444, Blast_Score=107, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6324800, Length=126, Percent_Identity=44.4444444444444, Blast_Score=107, Evalue=5e-25,
Organism=Drosophila melanogaster, GI21355597, Length=125, Percent_Identity=47.2, Blast_Score=112, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002871 [H]

Pfam domain/function: PF01592 NifU_N [H]

EC number: NA

Molecular weight: Translated: 15961; Mature: 15961

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNEYKGRKWGNFVYNKKVMDHFMNPRNVGEIENADGIGEAGNPHGDQMKIFLKIRDNRI
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
EDVKFKTFGCAAAIASSSMATEMIKGKTLEEAWELTDEAVAEALEGLPPGKLECSVVSRE
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHH
ATHRAINDYRKKQGLEPLEEKT
HHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKNEYKGRKWGNFVYNKKVMDHFMNPRNVGEIENADGIGEAGNPHGDQMKIFLKIRDNRI
CCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCC
EDVKFKTFGCAAAIASSSMATEMIKGKTLEEAWELTDEAVAEALEGLPPGKLECSVVSRE
CCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHH
ATHRAINDYRKKQGLEPLEEKT
HHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]