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The map label for this gene is cdhE [H]

Identifier: 21226160

GI number: 21226160

Start: 77762

End: 78226

Strand: Direct

Name: cdhE [H]

Synonym: MM_0058

Alternate gene names: 21226160

Gene position: 77762-78226 (Clockwise)

Preceding gene: 21226159

Following gene: 21226161

Centisome position: 1.9

GC content: 49.46

Gene sequence:

>465_bases
ATGACAAATGCAATGGAACTCTATCAGATGCTTCCAAAGACTAACTGCAAAAAATGTGGAAAAACCTCATGTATGGCTTT
TGCAGTTGCCCTTATGGCCCGCGAGCTGACACCAGAGGACTGCCCGCCCCTGAAAGAGGAACCCAAATATAAAGAAAGTT
ATGAAAAACTCAGCGAGATTTTCAAGCCTTCGGAAGGAGCAACCGAAACCGGACTTATAGTTCATGAAGACCTCTGTTTT
GGTTGCGGGAACTGCGTGGTTGCCTGCCCTCCGAATGTAGCAAATGACCCCTACGGAGTGGGCTCGGGAAAAGCCCCAAC
GAATCCTGGCAGGCTTGTCCTGACTGTTGAAGATGGAGTTGTGAAAGCCCAGAACCTGGGGGAGTGCCGCAGATTCGGGA
AGAACAAGATCCTCTGTAATGGCTGTATAGTGACCTGCCCTGTAGAGGCAATCGAGTTTGTGTGA

Upstream 100 bases:

>100_bases
CTGTGTGACGATAATGACATATGGCTAATCTGCCATCCTCTTTAATATAATTAAATTCAAGATAAATTAAATCACAAATT
TGACTCAAGGGTGACCTGGA

Downstream 100 bases:

>100_bases
GGCGAGAGGATGGAGAAAAACTATTACGTATGCACAGGCTGCGGGATGCTCTGCGATGACATAGAAGTAGATGTTGAAAA
TAATAAAATAAATAAAGTCT

Product: tungsten formylmethanofuran dehydrogenase subunit G

Products: CO2; methanofuran; reduced acceptor

Alternate protein names: ACDS complex subunit gamma; ACDS complex methyltransferase; Corrinoid/iron-sulfur component large subunit [H]

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MTNAMELYQMLPKTNCKKCGKTSCMAFAVALMARELTPEDCPPLKEEPKYKESYEKLSEIFKPSEGATETGLIVHEDLCF
GCGNCVVACPPNVANDPYGVGSGKAPTNPGRLVLTVEDGVVKAQNLGECRRFGKNKILCNGCIVTCPVEAIEFV

Sequences:

>Translated_154_residues
MTNAMELYQMLPKTNCKKCGKTSCMAFAVALMARELTPEDCPPLKEEPKYKESYEKLSEIFKPSEGATETGLIVHEDLCF
GCGNCVVACPPNVANDPYGVGSGKAPTNPGRLVLTVEDGVVKAQNLGECRRFGKNKILCNGCIVTCPVEAIEFV
>Mature_153_residues
TNAMELYQMLPKTNCKKCGKTSCMAFAVALMARELTPEDCPPLKEEPKYKESYEKLSEIFKPSEGATETGLIVHEDLCFG
CGNCVVACPPNVANDPYGVGSGKAPTNPGRLVLTVEDGVVKAQNLGECRRFGKNKILCNGCIVTCPVEAIEFV

Specific function: Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016041
- InterPro:   IPR016218
- InterPro:   IPR011005
- InterPro:   IPR007202
- InterPro:   IPR000489 [H]

Pfam domain/function: PF03599 CdhD; PF04060 FeS [H]

EC number: 1.2.99.5

Molecular weight: Translated: 16656; Mature: 16524

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

7.8 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
11.0 %Cys+Met (Translated Protein)
7.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
10.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNAMELYQMLPKTNCKKCGKTSCMAFAVALMARELTPEDCPPLKEEPKYKESYEKLSEI
CCHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
FKPSEGATETGLIVHEDLCFGCGNCVVACPPNVANDPYGVGSGKAPTNPGRLVLTVEDGV
HCCCCCCCCCCEEEECCHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCE
VKAQNLGECRRFGKNKILCNGCIVTCPVEAIEFV
ECHHHHHHHHHHCCCCEEECCEEEECCHHHHHCC
>Mature Secondary Structure 
TNAMELYQMLPKTNCKKCGKTSCMAFAVALMARELTPEDCPPLKEEPKYKESYEKLSEI
CHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHH
FKPSEGATETGLIVHEDLCFGCGNCVVACPPNVANDPYGVGSGKAPTNPGRLVLTVEDGV
HCCCCCCCCCCEEEECCHHHCCCCEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEECCCE
VKAQNLGECRRFGKNKILCNGCIVTCPVEAIEFV
ECHHHHHHHHHHCCCCEEECCEEEECCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: formylmethanofuran; H2O; acceptor

Specific reaction: formylmethanofuran + H2O + acceptor = CO2 + methanofuran + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]