| Definition | Methanosarcina mazei Go1 chromosome, complete genome. |
|---|---|
| Accession | NC_003901 |
| Length | 4,096,345 |
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The map label for this gene is helD [H]
Identifier: 21226130
GI number: 21226130
Start: 30530
End: 33127
Strand: Direct
Name: helD [H]
Synonym: MM_0028
Alternate gene names: 21226130
Gene position: 30530-33127 (Clockwise)
Preceding gene: 21226127
Following gene: 21226131
Centisome position: 0.75
GC content: 33.6
Gene sequence:
>2598_bases ATGGTTTTAGGCAATAGAAATGAAAATTTCTCAGATTTTAAAAAAGGTAAGCTAAGGTCATTTATTTTATCTATTATCTC TCCAATTGCACATTCATTTAAAAGAATTTACGAAATATGCATAACTGAAGTTCTGGAAGTCAGAAATAAAATTTTAAAAA TTGAAAAAGGAACCATAAGCGAAGAAGTAAAAAAAAATATTGAAAAGGATATATCTGAACTGTATTTAAAGCATGAATTA TACAATATAAGAAAGGAGTCTTATCTGACTTATCATGAACAGAAGGACCTAATTGATATTTGCGCAAAATGCCTAACTGC CTGTTCTTCTTTTAAAAATCGAAGTAAACTTTTCGATGAGCCATCCAATGATTTTGTTAATAAATCGATAACAGAATTGT CTTATTTGTCGAGTGAGTTTAAGAGATATAACAATAAAGAGTTTATTCAACAAAGAATCCAAAAGTATGATTACTTGTTC CAGAAATCTTCTTTTCCTCTAGATAACTCACAGAAAAGAGCAATAGTGACTGACGATACACATAATTTAGTTGTAGCAGG GGCTGGTTCTGGAAAAACCGAAGTTTTGATCACAAGAACTGCTTATCTAACGGAAAGAGCACCAGATAAAGTTGACGCAA AAAAGATACTCATTCTTGCTTATCAGAATAAAGCCGCTGAAGAGGTTAAAAAAAGACTTAAAGATAGGTTTAGTATTGAA GAGGCGGAAGTCAGAACTTTTCATTCATTGGGAAAGAAAATCTTGGAAGAAGGGAGCAAAATTTCTGGAAAAGAAACTCC CAAATTAAAGTTTTCAGGTTCTAATTTTGACAAAGAATTTTCAAATTATATTGATCATTTATTCAACCTTAGAAAGACAA ACGGAGATTTCCAGAAGAAAATTGTAGACTATATGAGATTATACCATGACAATGAGGTAATAAAGAGCCAGAAAGACTTT CAGAAAAAAGAAGAGTTCTACAAATATATGGCGAATTTAACATATACGGCTCTTGACGGAACTGAGGTCAAAAGTGAGGC TGAAAGGGCGATATTGAACTTTTTCATTAGTCATAACCTGAATGGAGAAAGAGCTAAAATACGTTATGAAGACCCCGCTA GATGGATGACGTATACTGATTCTAACGGTAATAAAAAGTCTCCAAAGCCCGATTTTTTCTTTCCAGATTATGATATTTAC CTTGAGCATTGGGCAATAGACAAAAATGGAAGAGTTCCAGACTGGTTTGAAGGTAAAAACGCGTCAGAAGAATACAAACT TGGGATGAAGAGAAAAAAAGAGAAGTTTGCACAGCAAGATAAATATTCTCTTGTAGAAATCGCAAGTTATGAATTCAAAG GGGAGAAATTTGAGGAAATTTTAATTGAAAGAATGACAAAGGCATTAAAAATAAAGTATCCCGATAAAGATTTTGAATTC ACCCCTGTTCCTTATGATCAACTTATCAGTAGAGTGAATTACGGATGCAAAGAATCTCTCAGAGGCCTTTCATTCAATGT TAGCAAATTCATAACAATTGCTAAAACATACAATCTGCCTCCAGAGAATATCAATCAAAGGTTACGAAGTGAAAGATGGT CTGCAAAACAAGAATCTTTTGCCAGGATCGTATTAGATATCTATGAGCTTTATGAAAACGAATTGAGAACTGAAAACAGG ATTGATTTTGCTGATATGATCAATCTTGCTGTAAAGGAACTGAAAGAGAATCAGGAACTATACAGAAATTCTTTTGCCCA AATTTTAATTGATGAATATCAGGATATAAGTTCTCAAAGATATGAGCTTATACGCGAACTTATGAAGAAGAATGATGGGT GTAAACTGTTCTGCGTAGGCGACGATTGGCAGAGTATAATGGGTTTCTCAGGTTCCGACCTTGACTTTTTTGTCAATTTC CATGAGTACTTCGACCATCCGGCCAGGACTGACCTTTCCACAAATTATAGAAGCTGTAAATCTATAGTGGACACAGGTGC TGAAATTATAAAATATAATAGAGACTCACAGATAGAAAAAGACACTTTTGCTAAGAATACTACCGAGAATCCTATAAGAA TATACGTCTCAAAACATAATCGAAGATCAACAAATATGTACTATTCTCAAATTGCCAGTCATTGCGTTTATTCAATAAAG CATTATCTTGATGACGGTTATGAACCGAAAGATATTCTACTTCTATCAAGAATTGGAAAAAATCTTAAGATGAAGAATAC GTTAATGGAATACGCTAAAACTCTAGATGTTCCTATTTCTTTTGATGGGAGTAAAAACCCGAATAAAATACCTTTTATGA CAGTACATAAAAGTAAGGGTTTACAGGCAAAAGCTGTTTTCCTGCTGGACGTGGTGGAAGACTTGTACGGTTTTCCCTGC GAAATAGAAAACCCAGATATTTTCGAGCCAGCAATTCTTTCACGTAAAAGAGATAGATATGAGGAAGAAAGGAGACTCTT TTACGTTGCTGTAACAAGAGCTATGAATGACCTGATAATTTACACCCGAAAAGATTCGGTAAGCAAATTTATACATGAAA TTGAAAACAAGGTTACTTTTTATGAACTCAATAACTGA
Upstream 100 bases:
>100_bases TTCAGTTTCCGATTTACCTACATTTTTATAGAATGTATGTATAAATATTCAGATCATACATATACAGAAATTTTTCTTCC AGCTACTAGAAGGCACTAGA
Downstream 100 bases:
>100_bases ATTAAAGTATCAGGGTTTTAATTCTCAAATATCCAAAACCGAATCCTCGAATTCTAAATAAAAAATTCTCCCTCAAACCA ATTCAATTGAAATATATTTT
Product: superfamily I DNA/RNA helicase
Products: NA
Alternate protein names: 75 kDa helicase [H]
Number of amino acids: Translated: 865; Mature: 865
Protein sequence:
>865_residues MVLGNRNENFSDFKKGKLRSFILSIISPIAHSFKRIYEICITEVLEVRNKILKIEKGTISEEVKKNIEKDISELYLKHEL YNIRKESYLTYHEQKDLIDICAKCLTACSSFKNRSKLFDEPSNDFVNKSITELSYLSSEFKRYNNKEFIQQRIQKYDYLF QKSSFPLDNSQKRAIVTDDTHNLVVAGAGSGKTEVLITRTAYLTERAPDKVDAKKILILAYQNKAAEEVKKRLKDRFSIE EAEVRTFHSLGKKILEEGSKISGKETPKLKFSGSNFDKEFSNYIDHLFNLRKTNGDFQKKIVDYMRLYHDNEVIKSQKDF QKKEEFYKYMANLTYTALDGTEVKSEAERAILNFFISHNLNGERAKIRYEDPARWMTYTDSNGNKKSPKPDFFFPDYDIY LEHWAIDKNGRVPDWFEGKNASEEYKLGMKRKKEKFAQQDKYSLVEIASYEFKGEKFEEILIERMTKALKIKYPDKDFEF TPVPYDQLISRVNYGCKESLRGLSFNVSKFITIAKTYNLPPENINQRLRSERWSAKQESFARIVLDIYELYENELRTENR IDFADMINLAVKELKENQELYRNSFAQILIDEYQDISSQRYELIRELMKKNDGCKLFCVGDDWQSIMGFSGSDLDFFVNF HEYFDHPARTDLSTNYRSCKSIVDTGAEIIKYNRDSQIEKDTFAKNTTENPIRIYVSKHNRRSTNMYYSQIASHCVYSIK HYLDDGYEPKDILLLSRIGKNLKMKNTLMEYAKTLDVPISFDGSKNPNKIPFMTVHKSKGLQAKAVFLLDVVEDLYGFPC EIENPDIFEPAILSRKRDRYEEERRLFYVAVTRAMNDLIIYTRKDSVSKFIHEIENKVTFYELNN
Sequences:
>Translated_865_residues MVLGNRNENFSDFKKGKLRSFILSIISPIAHSFKRIYEICITEVLEVRNKILKIEKGTISEEVKKNIEKDISELYLKHEL YNIRKESYLTYHEQKDLIDICAKCLTACSSFKNRSKLFDEPSNDFVNKSITELSYLSSEFKRYNNKEFIQQRIQKYDYLF QKSSFPLDNSQKRAIVTDDTHNLVVAGAGSGKTEVLITRTAYLTERAPDKVDAKKILILAYQNKAAEEVKKRLKDRFSIE EAEVRTFHSLGKKILEEGSKISGKETPKLKFSGSNFDKEFSNYIDHLFNLRKTNGDFQKKIVDYMRLYHDNEVIKSQKDF QKKEEFYKYMANLTYTALDGTEVKSEAERAILNFFISHNLNGERAKIRYEDPARWMTYTDSNGNKKSPKPDFFFPDYDIY LEHWAIDKNGRVPDWFEGKNASEEYKLGMKRKKEKFAQQDKYSLVEIASYEFKGEKFEEILIERMTKALKIKYPDKDFEF TPVPYDQLISRVNYGCKESLRGLSFNVSKFITIAKTYNLPPENINQRLRSERWSAKQESFARIVLDIYELYENELRTENR IDFADMINLAVKELKENQELYRNSFAQILIDEYQDISSQRYELIRELMKKNDGCKLFCVGDDWQSIMGFSGSDLDFFVNF HEYFDHPARTDLSTNYRSCKSIVDTGAEIIKYNRDSQIEKDTFAKNTTENPIRIYVSKHNRRSTNMYYSQIASHCVYSIK HYLDDGYEPKDILLLSRIGKNLKMKNTLMEYAKTLDVPISFDGSKNPNKIPFMTVHKSKGLQAKAVFLLDVVEDLYGFPC EIENPDIFEPAILSRKRDRYEEERRLFYVAVTRAMNDLIIYTRKDSVSKFIHEIENKVTFYELNN >Mature_865_residues MVLGNRNENFSDFKKGKLRSFILSIISPIAHSFKRIYEICITEVLEVRNKILKIEKGTISEEVKKNIEKDISELYLKHEL YNIRKESYLTYHEQKDLIDICAKCLTACSSFKNRSKLFDEPSNDFVNKSITELSYLSSEFKRYNNKEFIQQRIQKYDYLF QKSSFPLDNSQKRAIVTDDTHNLVVAGAGSGKTEVLITRTAYLTERAPDKVDAKKILILAYQNKAAEEVKKRLKDRFSIE EAEVRTFHSLGKKILEEGSKISGKETPKLKFSGSNFDKEFSNYIDHLFNLRKTNGDFQKKIVDYMRLYHDNEVIKSQKDF QKKEEFYKYMANLTYTALDGTEVKSEAERAILNFFISHNLNGERAKIRYEDPARWMTYTDSNGNKKSPKPDFFFPDYDIY LEHWAIDKNGRVPDWFEGKNASEEYKLGMKRKKEKFAQQDKYSLVEIASYEFKGEKFEEILIERMTKALKIKYPDKDFEF TPVPYDQLISRVNYGCKESLRGLSFNVSKFITIAKTYNLPPENINQRLRSERWSAKQESFARIVLDIYELYENELRTENR IDFADMINLAVKELKENQELYRNSFAQILIDEYQDISSQRYELIRELMKKNDGCKLFCVGDDWQSIMGFSGSDLDFFVNF HEYFDHPARTDLSTNYRSCKSIVDTGAEIIKYNRDSQIEKDTFAKNTTENPIRIYVSKHNRRSTNMYYSQIASHCVYSIK HYLDDGYEPKDILLLSRIGKNLKMKNTLMEYAKTLDVPISFDGSKNPNKIPFMTVHKSKGLQAKAVFLLDVVEDLYGFPC EIENPDIFEPAILSRKRDRYEEERRLFYVAVTRAMNDLIIYTRKDSVSKFIHEIENKVTFYELNN
Specific function: Helicase IV catalyzes the unwinding of duplex DNA in the 3' to 5' direction with respect to the bound single strand in a reaction that is dependent upon the hydrolysis of ATP [H]
COG id: COG0210
COG function: function code L; Superfamily I DNA and RNA helicases
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 uvrD-like helicase ATP-binding domain [H]
Homologues:
Organism=Escherichia coli, GI1787196, Length=320, Percent_Identity=31.5625, Blast_Score=131, Evalue=2e-31, Organism=Escherichia coli, GI2367296, Length=155, Percent_Identity=30.3225806451613, Blast_Score=70, Evalue=5e-13,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR000212 - InterPro: IPR014016 - InterPro: IPR022161 - InterPro: IPR003661 [H]
Pfam domain/function: PF12462 Nucleolin_N; PF00580 UvrD-helicase [H]
EC number: =3.6.4.12 [H]
Molecular weight: Translated: 101763; Mature: 101763
Theoretical pI: Translated: 8.51; Mature: 8.51
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.2 %Cys (Translated Protein) 1.6 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 1.2 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.8 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MVLGNRNENFSDFKKGKLRSFILSIISPIAHSFKRIYEICITEVLEVRNKILKIEKGTIS CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHH EEVKKNIEKDISELYLKHELYNIRKESYLTYHEQKDLIDICAKCLTACSSFKNRSKLFDE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC PSNDFVNKSITELSYLSSEFKRYNNKEFIQQRIQKYDYLFQKSSFPLDNSQKRAIVTDDT CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCC HNLVVAGAGSGKTEVLITRTAYLTERAPDKVDAKKILILAYQNKAAEEVKKRLKDRFSIE CCEEEEECCCCCCEEEEEEHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCH EAEVRTFHSLGKKILEEGSKISGKETPKLKFSGSNFDKEFSNYIDHLFNLRKTNGDFQKK HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHH IVDYMRLYHDNEVIKSQKDFQKKEEFYKYMANLTYTALDGTEVKSEAERAILNFFISHNL HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCC NGERAKIRYEDPARWMTYTDSNGNKKSPKPDFFFPDYDIYLEHWAIDKNGRVPDWFEGKN CCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCHHEEEEEEEECCCCCCCCCCCCCC ASEEYKLGMKRKKEKFAQQDKYSLVEIASYEFKGEKFEEILIERMTKALKIKYPDKDFEF CCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHEEECCCCCCCC TPVPYDQLISRVNYGCKESLRGLSFNVSKFITIAKTYNLPPENINQRLRSERWSAKQESF CCCCHHHHHHHHCCCHHHHHCCCCCCHHHHEEEEHCCCCCHHHHHHHHHHHHCCHHHHHH ARIVLDIYELYENELRTENRIDFADMINLAVKELKENQELYRNSFAQILIDEYQDISSQR HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH YELIRELMKKNDGCKLFCVGDDWQSIMGFSGSDLDFFVNFHEYFDHPARTDLSTNYRSCK HHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCHHEEEEHHHHCCCCCCCCCCCCHHHHH SIVDTGAEIIKYNRDSQIEKDTFAKNTTENPIRIYVSKHNRRSTNMYYSQIASHCVYSIK HHHHCCHHHHCCCCCCCCCHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH HYLDDGYEPKDILLLSRIGKNLKMKNTLMEYAKTLDVPISFDGSKNPNKIPFMTVHKSKG HHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCEEEEECCCC LQAKAVFLLDVVEDLYGFPCEIENPDIFEPAILSRKRDRYEEERRLFYVAVTRAMNDLII CCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEHHHHHHHHCCEEE YTRKDSVSKFIHEIENKVTFYELNN EECCHHHHHHHHHHHCCEEEEEECC >Mature Secondary Structure MVLGNRNENFSDFKKGKLRSFILSIISPIAHSFKRIYEICITEVLEVRNKILKIEKGTIS CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHH EEVKKNIEKDISELYLKHELYNIRKESYLTYHEQKDLIDICAKCLTACSSFKNRSKLFDE HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC PSNDFVNKSITELSYLSSEFKRYNNKEFIQQRIQKYDYLFQKSSFPLDNSQKRAIVTDDT CCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEECCC HNLVVAGAGSGKTEVLITRTAYLTERAPDKVDAKKILILAYQNKAAEEVKKRLKDRFSIE CCEEEEECCCCCCEEEEEEHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHCCCH EAEVRTFHSLGKKILEEGSKISGKETPKLKFSGSNFDKEFSNYIDHLFNLRKTNGDFQKK HHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHH IVDYMRLYHDNEVIKSQKDFQKKEEFYKYMANLTYTALDGTEVKSEAERAILNFFISHNL HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHHHHHHCCC NGERAKIRYEDPARWMTYTDSNGNKKSPKPDFFFPDYDIYLEHWAIDKNGRVPDWFEGKN CCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCHHEEEEEEEECCCCCCCCCCCCCC ASEEYKLGMKRKKEKFAQQDKYSLVEIASYEFKGEKFEEILIERMTKALKIKYPDKDFEF CCHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHEEECCCCCCCC TPVPYDQLISRVNYGCKESLRGLSFNVSKFITIAKTYNLPPENINQRLRSERWSAKQESF CCCCHHHHHHHHCCCHHHHHCCCCCCHHHHEEEEHCCCCCHHHHHHHHHHHHCCHHHHHH ARIVLDIYELYENELRTENRIDFADMINLAVKELKENQELYRNSFAQILIDEYQDISSQR HHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH YELIRELMKKNDGCKLFCVGDDWQSIMGFSGSDLDFFVNFHEYFDHPARTDLSTNYRSCK HHHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCHHEEEEHHHHCCCCCCCCCCCCHHHHH SIVDTGAEIIKYNRDSQIEKDTFAKNTTENPIRIYVSKHNRRSTNMYYSQIASHCVYSIK HHHHCCHHHHCCCCCCCCCHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHH HYLDDGYEPKDILLLSRIGKNLKMKNTLMEYAKTLDVPISFDGSKNPNKIPFMTVHKSKG HHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEECCCCCCCCCCCEEEEECCCC LQAKAVFLLDVVEDLYGFPCEIENPDIFEPAILSRKRDRYEEERRLFYVAVTRAMNDLII CCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEHHHHHHHHCCEEE YTRKDSVSKFIHEIENKVTFYELNN EECCHHHHHHHHHHHCCEEEEEECC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2542273; 8905232; 9278503 [H]