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The map label for this gene is eif1a2 [H]

Identifier: 21226118

GI number: 21226118

Start: 18916

End: 19098

Strand: Direct

Name: eif1a2 [H]

Synonym: MM_0016

Alternate gene names: 21226118

Gene position: 18916-19098 (Clockwise)

Preceding gene: 21226116

Following gene: 21226120

Centisome position: 0.46

GC content: 48.63

Gene sequence:

>183_bases
ATGGACGGAGTTGTCCGCATGGGAAGGATTCCGGGCTCTAAAAAAAAGAGAATGTGGATCCGCGAAGGTGATGTAGTAAT
AGCCAATCCCTGGGAAGTTCAGGACTCCAAAGCCGAAGTTACCTGGAAATACACCAGGCCCCAGGTAGAATGGCTTGAGC
GGAAAGGCTATCTTAAGTATTGA

Upstream 100 bases:

>100_bases
ACCTGAAACATCAAGAGTACGAGTCCCTCGCAAGGACAGAAATGAAGTTCTGGCAACGGTTGCAAGTTTACTCGGCTCGA
AAAGAGTGACACTTCAGTGC

Downstream 100 bases:

>100_bases
TTTAAAGGTATCGATAAGGATGCCTGATAAAACAGGTATCTAAAAGAGGTGTCTGAAAAAAGACGCCTAAAATCTACATT
TTACTTTTCTGAGAAGCATT

Product: translation initiation factor IF-1A

Products: NA

Alternate protein names: aIF-1A 2 [H]

Number of amino acids: Translated: 60; Mature: 60

Protein sequence:

>60_residues
MDGVVRMGRIPGSKKKRMWIREGDVVIANPWEVQDSKAEVTWKYTRPQVEWLERKGYLKY

Sequences:

>Translated_60_residues
MDGVVRMGRIPGSKKKRMWIREGDVVIANPWEVQDSKAEVTWKYTRPQVEWLERKGYLKY
>Mature_60_residues
MDGVVRMGRIPGSKKKRMWIREGDVVIANPWEVQDSKAEVTWKYTRPQVEWLERKGYLKY

Specific function: Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits [H]

COG id: COG0361

COG function: function code J; Translation initiation factor 1 (IF-1)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR006196
- InterPro:   IPR001253
- InterPro:   IPR018104
- ProDom:   PD005579 [H]

Pfam domain/function: PF01176 eIF-1a [H]

EC number: NA

Molecular weight: Translated: 7196; Mature: 7196

Theoretical pI: Translated: 10.39; Mature: 10.39

Prosite motif: PS50832 S1_IF1_TYPE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDGVVRMGRIPGSKKKRMWIREGDVVIANPWEVQDSKAEVTWKYTRPQVEWLERKGYLKY
CCCCCCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCEEEEEEECCCCHHHHHCCCCCCC
>Mature Secondary Structure
MDGVVRMGRIPGSKKKRMWIREGDVVIANPWEVQDSKAEVTWKYTRPQVEWLERKGYLKY
CCCCCCCCCCCCCCCCEEEEECCCEEEECCCCCCCCCEEEEEEECCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA