Click here to switch to the map view.

The map label for this gene is BtuC [H]

Identifier: 20806885

GI number: 20806885

Start: 397360

End: 398352

Strand: Direct

Name: BtuC [H]

Synonym: TTE0373

Alternate gene names: 20806885

Gene position: 397360-398352 (Clockwise)

Preceding gene: 20806884

Following gene: 20806886

Centisome position: 14.77

GC content: 42.09

Gene sequence:

>993_bases
GTGAAGGCTAAGAGAGGTTTTTACTTTACATCAGCATTTTTACTCCTTCTTTTGATAATGGCTCTTTCAATTTCTGCAGG
GGCGGTGCACATCCCCCTGCAGGAAATACTAAATGTGCTTTTGGGGAAAGGGGATGAAGTCAACAGGCGCATTATACTTA
CATTAAGGCTTCCAAGAGTTATAGAATCAGCTCTTGTGGGCATGGGACTATCTGTTGTGGGAGCTTTTTTCCAGGGGCTT
TTGAGAAATCCCATGGCAGACCCTTATGTTTTGGGTATATCTTCAGGTGCAGCTTTTGGAGCTACAATTGCCATAATAAT
GGGTTTAGGCATATTTGGCTTAAGCTCTATGGCTTTCATAACAGCCCTTTTGACAATATTTTTTGTGTACACTGTGTCAA
GGACGGGTTCCAGGCTTTCAATGACCACAATGCTTCTGGCTGGAATTGCCATAAGCGCTTTTATGTCTGCCATAATCTCT
TTGCTCATGCTTTTAAACCATGACCAGTTTTCACGGATTGTTTTCTGGACTATGGGGGGTTTTGGCCTTGTGAGCTGGCC
ACAGGTTATCTACTCTTCGCCTTTAATACTCATAGGTTCTTTTGTTATGTACGCATTTTCAAGGGATGTAAATGTCATTT
TAACAGGGGAAGAATCTGCAGAGCATTTAGGTGTAAATGCGGAGCTTGTCAAGAAAATTATACTTATCTTGGGGTCATTG
GTGACAGCTTCTTGTGTCTCTGTTGGAGGAATTATAGGCTTTGTAGGGCTTATAGTTCCACATATTTCAAGGTTTATTGT
AGGACCTGACAACAGAGTTCTGGTTCCCTTTAGTGCTCTTTTTGGCGCTTCTTTTCTCACCTTTGCAGACCTTTTGGCGA
GAGTGATTTTAAAGCCTGTAGAGATGCCAATAGGGATAATTACGGCGACTTTTGGAGGGCCCTTTTTCCTGTATCTCCTT
GTAAGGAGCAAGCAAAAAAATGAAGGAATGTGA

Upstream 100 bases:

>100_bases
GTGGTGTCCAATGACGACATAATTGTAAGAGGAACAAATAGGATTGTATTAGGGCTTGAAGAAGTAGCAAAATTCTTACA
TCCGGAGGCATTTAAATAAA

Downstream 100 bases:

>100_bases
TATTATGTCTATTTTAGAAGTGAAAGACCTCTATTTCTCTTATGGGCAGAAGCGGGTATTGAAAGGGATAAATTTAAAAG
TGGACAAAAGTGAAATGATA

Product: ABC-type cobalamin/Fe3+-siderophores transport systems, permease components

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 330; Mature: 330

Protein sequence:

>330_residues
MKAKRGFYFTSAFLLLLLIMALSISAGAVHIPLQEILNVLLGKGDEVNRRIILTLRLPRVIESALVGMGLSVVGAFFQGL
LRNPMADPYVLGISSGAAFGATIAIIMGLGIFGLSSMAFITALLTIFFVYTVSRTGSRLSMTTMLLAGIAISAFMSAIIS
LLMLLNHDQFSRIVFWTMGGFGLVSWPQVIYSSPLILIGSFVMYAFSRDVNVILTGEESAEHLGVNAELVKKIILILGSL
VTASCVSVGGIIGFVGLIVPHISRFIVGPDNRVLVPFSALFGASFLTFADLLARVILKPVEMPIGIITATFGGPFFLYLL
VRSKQKNEGM

Sequences:

>Translated_330_residues
MKAKRGFYFTSAFLLLLLIMALSISAGAVHIPLQEILNVLLGKGDEVNRRIILTLRLPRVIESALVGMGLSVVGAFFQGL
LRNPMADPYVLGISSGAAFGATIAIIMGLGIFGLSSMAFITALLTIFFVYTVSRTGSRLSMTTMLLAGIAISAFMSAIIS
LLMLLNHDQFSRIVFWTMGGFGLVSWPQVIYSSPLILIGSFVMYAFSRDVNVILTGEESAEHLGVNAELVKKIILILGSL
VTASCVSVGGIIGFVGLIVPHISRFIVGPDNRVLVPFSALFGASFLTFADLLARVILKPVEMPIGIITATFGGPFFLYLL
VRSKQKNEGM
>Mature_330_residues
MKAKRGFYFTSAFLLLLLIMALSISAGAVHIPLQEILNVLLGKGDEVNRRIILTLRLPRVIESALVGMGLSVVGAFFQGL
LRNPMADPYVLGISSGAAFGATIAIIMGLGIFGLSSMAFITALLTIFFVYTVSRTGSRLSMTTMLLAGIAISAFMSAIIS
LLMLLNHDQFSRIVFWTMGGFGLVSWPQVIYSSPLILIGSFVMYAFSRDVNVILTGEESAEHLGVNAELVKKIILILGSL
VTASCVSVGGIIGFVGLIVPHISRFIVGPDNRVLVPFSALFGASFLTFADLLARVILKPVEMPIGIITATFGGPFFLYLL
VRSKQKNEGM

Specific function: Probably part of an ABC transporter complex. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=305, Percent_Identity=31.4754098360656, Blast_Score=147, Evalue=8e-37,
Organism=Escherichia coli, GI1790741, Length=291, Percent_Identity=32.9896907216495, Blast_Score=142, Evalue=3e-35,
Organism=Escherichia coli, GI1786805, Length=307, Percent_Identity=32.8990228013029, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788004, Length=289, Percent_Identity=34.9480968858132, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1786804, Length=307, Percent_Identity=25.0814332247557, Blast_Score=107, Evalue=9e-25,
Organism=Escherichia coli, GI1786347, Length=276, Percent_Identity=29.7101449275362, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 35432; Mature: 35432

Theoretical pI: Translated: 10.20; Mature: 10.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAKRGFYFTSAFLLLLLIMALSISAGAVHIPLQEILNVLLGKGDEVNRRIILTLRLPRV
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCCCCCEEEEEEECHHH
IESALVGMGLSVVGAFFQGLLRNPMADPYVLGISSGAAFGATIAIIMGLGIFGLSSMAFI
HHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
TALLTIFFVYTVSRTGSRLSMTTMLLAGIAISAFMSAIISLLMLLNHDQFSRIVFWTMGG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCC
FGLVSWPQVIYSSPLILIGSFVMYAFSRDVNVILTGEESAEHLGVNAELVKKIILILGSL
CCHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCHHHCCCCHHHHHHHHHHHHHH
VTASCVSVGGIIGFVGLIVPHISRFIVGPDNRVLVPFSALFGASFLTFADLLARVILKPV
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
EMPIGIITATFGGPFFLYLLVRSKQKNEGM
CCCCEEEEECCCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKAKRGFYFTSAFLLLLLIMALSISAGAVHIPLQEILNVLLGKGDEVNRRIILTLRLPRV
CCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHCCCCCCCCEEEEEEECHHH
IESALVGMGLSVVGAFFQGLLRNPMADPYVLGISSGAAFGATIAIIMGLGIFGLSSMAFI
HHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
TALLTIFFVYTVSRTGSRLSMTTMLLAGIAISAFMSAIISLLMLLNHDQFSRIVFWTMGG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEEEECCC
FGLVSWPQVIYSSPLILIGSFVMYAFSRDVNVILTGEESAEHLGVNAELVKKIILILGSL
CCHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEECCCCHHHCCCCHHHHHHHHHHHHHH
VTASCVSVGGIIGFVGLIVPHISRFIVGPDNRVLVPFSALFGASFLTFADLLARVILKPV
HHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
EMPIGIITATFGGPFFLYLLVRSKQKNEGM
CCCCEEEEECCCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9639930; 9384377 [H]