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The map label for this gene is PurR3 [H]

Identifier: 20806866

GI number: 20806866

Start: 373480

End: 374565

Strand: Direct

Name: PurR3 [H]

Synonym: TTE0349

Alternate gene names: 20806866

Gene position: 373480-374565 (Clockwise)

Preceding gene: 20806865

Following gene: 20806867

Centisome position: 13.89

GC content: 35.08

Gene sequence:

>1086_bases
ATGATTAATAGCAAAGACATTGCTAGGATTGCCGGTGTGTCTCGCAGTACTGTGTCAAGAGTCATAAATAATTATCCCAA
TGTTTCGCCTGAAACTAAGGAAAAAGTGTTAAAAGCTATTAAGGAATATAACTATGTTCCTCATGCTTCAGCTCGCATGT
TGAGAGGAAAAAGCTCTAAGACGATTGGCCTTGTGATTGTAGATTTGAAGAGGAATAGTGATATTCATAAGGTTTATGAC
AATGTTTACTTTGGACCTTTTACAACTGCGGTTATCGATTTTGCAAATCAGCTAGGATATAATGTTCTTGTCATTACTGT
TTATAAACCGAAAGATTATAAAAAAGTGAGGGAAGTCTTTTACAATAAGACTATCAATGGAGCAATTTTTATTGGTGTAA
AAAATGATGACCCCGAAATAAAAAATCTTATTGAGGCAGGGCTTAAGACGGCAGTGATTGACCAGGAAATAAGAGATGAT
GAGAATGACCCATTCAATAAAAGTATCATAGTCAACATGGATAATGTGACTGGAGCCTATGAAGCTACAAAGTACTTGAT
AAGTCTGGGTCACAGGGAAATTGCCCATATAACAGGTGATATGGAAAAGCTCTCTGGTTTTGCAAGATTAGAAGGATACA
AGAAAGCATTGAAAGAAGCGGGAATTCCATTTAAAAGTAGTCTGGTAGTAAAAGGGGATTTTGTTGAAGAAAGCGGTTAT
AAGGCTGCATATAAATTATTCAAAAAAGCAAAACCCACGGCGATTTTTGCTTCAAATGATCAGATGGCTATAGGAGCTAT
GCAGGCTTTAGAAGAGATGGGATACAAAATTCCAGATGATGTTTCTATAATTGGTTTTGATGATATTACTATATCTCGCT
ATTTGAAACCTGCTTTAACGACGATGAGCGTTTCTTTATTGCAAATGGCAGAGTTAGCAGTAGAAAATCTTATTAGGTCA
GTCGAGGAAGAGATAGCAATTAAAGCTAAATTTGTAGTACCTGTAAAACTGGTAGAAAGAGAATCTTGTAAAAGAATTGA
GATAAAAGAAGAAAATGAAAAGAAAGAATATCTTTTATCAAGATGA

Upstream 100 bases:

>100_bases
ACACGTGTTCATGAAATTTATTTTAAGAGTTTTTGTTGAAAAATGCGAAAAGTTACTCTATAATCTATAACAAACAATAT
AGAAATAGAGGAGAATTGTT

Downstream 100 bases:

>100_bases
AGGTCAACATTTTTGTTTCTATACTCTTTTGTAAACACGTGTTTATTGGATTTTTGTATAATATATGGTATAAAAAGGCT
TAAAGCCTTTTTAATCTAAA

Product: transcriptional regulator

Products: NA

Alternate protein names: Degradation activator [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MINSKDIARIAGVSRSTVSRVINNYPNVSPETKEKVLKAIKEYNYVPHASARMLRGKSSKTIGLVIVDLKRNSDIHKVYD
NVYFGPFTTAVIDFANQLGYNVLVITVYKPKDYKKVREVFYNKTINGAIFIGVKNDDPEIKNLIEAGLKTAVIDQEIRDD
ENDPFNKSIIVNMDNVTGAYEATKYLISLGHREIAHITGDMEKLSGFARLEGYKKALKEAGIPFKSSLVVKGDFVEESGY
KAAYKLFKKAKPTAIFASNDQMAIGAMQALEEMGYKIPDDVSIIGFDDITISRYLKPALTTMSVSLLQMAELAVENLIRS
VEEEIAIKAKFVVPVKLVERESCKRIEIKEENEKKEYLLSR

Sequences:

>Translated_361_residues
MINSKDIARIAGVSRSTVSRVINNYPNVSPETKEKVLKAIKEYNYVPHASARMLRGKSSKTIGLVIVDLKRNSDIHKVYD
NVYFGPFTTAVIDFANQLGYNVLVITVYKPKDYKKVREVFYNKTINGAIFIGVKNDDPEIKNLIEAGLKTAVIDQEIRDD
ENDPFNKSIIVNMDNVTGAYEATKYLISLGHREIAHITGDMEKLSGFARLEGYKKALKEAGIPFKSSLVVKGDFVEESGY
KAAYKLFKKAKPTAIFASNDQMAIGAMQALEEMGYKIPDDVSIIGFDDITISRYLKPALTTMSVSLLQMAELAVENLIRS
VEEEIAIKAKFVVPVKLVERESCKRIEIKEENEKKEYLLSR
>Mature_361_residues
MINSKDIARIAGVSRSTVSRVINNYPNVSPETKEKVLKAIKEYNYVPHASARMLRGKSSKTIGLVIVDLKRNSDIHKVYD
NVYFGPFTTAVIDFANQLGYNVLVITVYKPKDYKKVREVFYNKTINGAIFIGVKNDDPEIKNLIEAGLKTAVIDQEIRDD
ENDPFNKSIIVNMDNVTGAYEATKYLISLGHREIAHITGDMEKLSGFARLEGYKKALKEAGIPFKSSLVVKGDFVEESGY
KAAYKLFKKAKPTAIFASNDQMAIGAMQALEEMGYKIPDDVSIIGFDDITISRYLKPALTTMSVSLLQMAELAVENLIRS
VEEEIAIKAKFVVPVKLVERESCKRIEIKEENEKKEYLLSR

Specific function: Involved in the control of degradation of B.subtilis amidophosphoribosyltransferase (purF). Probably activates the gene for a degradative protease [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=346, Percent_Identity=34.1040462427746, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1790194, Length=346, Percent_Identity=32.0809248554913, Blast_Score=171, Evalue=8e-44,
Organism=Escherichia coli, GI1789068, Length=325, Percent_Identity=32.9230769230769, Blast_Score=164, Evalue=7e-42,
Organism=Escherichia coli, GI1788474, Length=344, Percent_Identity=33.7209302325581, Blast_Score=162, Evalue=3e-41,
Organism=Escherichia coli, GI1789202, Length=314, Percent_Identity=32.1656050955414, Blast_Score=156, Evalue=2e-39,
Organism=Escherichia coli, GI1790369, Length=302, Percent_Identity=31.7880794701987, Blast_Score=148, Evalue=5e-37,
Organism=Escherichia coli, GI1786540, Length=342, Percent_Identity=30.1169590643275, Blast_Score=146, Evalue=2e-36,
Organism=Escherichia coli, GI1787580, Length=316, Percent_Identity=29.4303797468354, Blast_Score=132, Evalue=2e-32,
Organism=Escherichia coli, GI48994940, Length=328, Percent_Identity=25.9146341463415, Blast_Score=112, Evalue=4e-26,
Organism=Escherichia coli, GI1787906, Length=351, Percent_Identity=24.5014245014245, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789456, Length=353, Percent_Identity=24.929178470255, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786268, Length=329, Percent_Identity=25.2279635258359, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1790689, Length=342, Percent_Identity=25.4385964912281, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790715, Length=329, Percent_Identity=22.7963525835866, Blast_Score=76, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 40541; Mature: 40541

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINSKDIARIAGVSRSTVSRVINNYPNVSPETKEKVLKAIKEYNYVPHASARMLRGKSSK
CCCCHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCC
TIGLVIVDLKRNSDIHKVYDNVYFGPFTTAVIDFANQLGYNVLVITVYKPKDYKKVREVF
EEEEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHH
YNKTINGAIFIGVKNDDPEIKNLIEAGLKTAVIDQEIRDDENDPFNKSIIVNMDNVTGAY
HCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHH
EATKYLISLGHREIAHITGDMEKLSGFARLEGYKKALKEAGIPFKSSLVVKGDFVEESGY
HHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCH
KAAYKLFKKAKPTAIFASNDQMAIGAMQALEEMGYKIPDDVSIIGFDDITISRYLKPALT
HHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHH
TMSVSLLQMAELAVENLIRSVEEEIAIKAKFVVPVKLVERESCKRIEIKEENEKKEYLLS
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEHHHHCCCCCCEEEECCCCCHHHHHCC
R
C
>Mature Secondary Structure
MINSKDIARIAGVSRSTVSRVINNYPNVSPETKEKVLKAIKEYNYVPHASARMLRGKSSK
CCCCHHHHHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCC
TIGLVIVDLKRNSDIHKVYDNVYFGPFTTAVIDFANQLGYNVLVITVYKPKDYKKVREVF
EEEEEEEEECCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCEEEEEEEECCCHHHHHHHHH
YNKTINGAIFIGVKNDDPEIKNLIEAGLKTAVIDQEIRDDENDPFNKSIIVNMDNVTGAY
HCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCHH
EATKYLISLGHREIAHITGDMEKLSGFARLEGYKKALKEAGIPFKSSLVVKGDFVEESGY
HHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCH
KAAYKLFKKAKPTAIFASNDQMAIGAMQALEEMGYKIPDDVSIIGFDDITISRYLKPALT
HHHHHHHHHCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCEEEEECCHHHHHHHHHHHH
TMSVSLLQMAELAVENLIRSVEEEIAIKAKFVVPVKLVERESCKRIEIKEENEKKEYLLS
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEEHHHHCCCCCCEEEECCCCCHHHHHCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8407808; 9353932; 9384377 [H]