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The map label for this gene is SlpA [C]

Identifier: 20094667

GI number: 20094667

Start: 1217045

End: 1217704

Strand: Reverse

Name: SlpA [C]

Synonym: MK1231

Alternate gene names: 20094667

Gene position: 1217704-1217045 (Counterclockwise)

Preceding gene: 20094668

Following gene: 20094665

Centisome position: 71.84

GC content: 65.3

Gene sequence:

>660_bases
GTGGCCGTTGAGAAGGGTGACTTCGTGAAGATCCACTACACGGGACGCGTGAAGGACACCGACGAGGTAATCGACACCAC
ACGGAAGGAGGTCGCGGAAGAGCACGATCTGAACGTCGAGTCCGGCCCGGTGGTGGTCGTGGTCGGAGCCGGAATGGTAT
GGGAACCGGTTGAGGAGGCACTGGTGGGCGCGGAACCAGGGGACGAGTTGGAGGTCGAGGTGCCCCCGGAGAAGGCCTTC
GGGGAGCGTGACCCATCGCTGGTCCGGACGTACCGTGAGTCCGAGTTCAGGGGGAGCGTGAAGCCCGGGGATACCGTCGT
AAGTCCCGACGGCCGGCGCGGTCGCGTGCTCAGCGTCGACGGTGGACGGGTGAGGGTCGACTTCAACCACCCGCTGGCGG
GTAAAGCGCTGGTGTACGAGGTGGAAGTCGTGGACGTACTGGAGGACACGGTGGAGCGGGCGGAGGGCCTGCTGGAGACG
ATGGTGCCATCCGTCGACGCGGAGCTGGAGCTGGACGGGAACACGCTGCGCGTCAGGGTGGAAGGCGACGACGCCGCCAA
TCCGGCGTGGGCCCGGGCGAAGCAGAGGTTCGCGAAGCTGATGATAGAGTACGACGACGCCGTGGAAGAGGTCGTGTTCG
AAGAGCGGTTCACTGAATGA

Upstream 100 bases:

>100_bases
CCGTGGAGAAGAAGGAGGTCGAGACCCTGATGTCCCGAGGTCTCTCGGAGGAAGAAGCCGTCGAACTACTCGTGAACGCG
ATGCTGAGGGGTTGATCGTC

Downstream 100 bases:

>100_bases
CGCCCGTCTCCTCGGCCGCCCTCTCCGCGGCCTCGCGCGTCAGTCCTTTATCCCCCAAGATGGTGTACCGGTCCGGACGT
ATCTTGTGCGCCCGGCAGAG

Product: FKBP-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MAVEKGDFVKIHYTGRVKDTDEVIDTTRKEVAEEHDLNVESGPVVVVVGAGMVWEPVEEALVGAEPGDELEVEVPPEKAF
GERDPSLVRTYRESEFRGSVKPGDTVVSPDGRRGRVLSVDGGRVRVDFNHPLAGKALVYEVEVVDVLEDTVERAEGLLET
MVPSVDAELELDGNTLRVRVEGDDAANPAWARAKQRFAKLMIEYDDAVEEVVFEERFTE

Sequences:

>Translated_219_residues
MAVEKGDFVKIHYTGRVKDTDEVIDTTRKEVAEEHDLNVESGPVVVVVGAGMVWEPVEEALVGAEPGDELEVEVPPEKAF
GERDPSLVRTYRESEFRGSVKPGDTVVSPDGRRGRVLSVDGGRVRVDFNHPLAGKALVYEVEVVDVLEDTVERAEGLLET
MVPSVDAELELDGNTLRVRVEGDDAANPAWARAKQRFAKLMIEYDDAVEEVVFEERFTE
>Mature_218_residues
AVEKGDFVKIHYTGRVKDTDEVIDTTRKEVAEEHDLNVESGPVVVVVGAGMVWEPVEEALVGAEPGDELEVEVPPEKAFG
ERDPSLVRTYRESEFRGSVKPGDTVVSPDGRRGRVLSVDGGRVRVDFNHPLAGKALVYEVEVVDVLEDTVERAEGLLETM
VPSVDAELELDGNTLRVRVEGDDAANPAWARAKQRFAKLMIEYDDAVEEVVFEERFTE

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1786211, Length=151, Percent_Identity=26.4900662251656, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 24237; Mature: 24106

Theoretical pI: Translated: 4.15; Mature: 4.15

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVEKGDFVKIHYTGRVKDTDEVIDTTRKEVAEEHDLNVESGPVVVVVGAGMVWEPVEEA
CCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHH
LVGAEPGDELEVEVPPEKAFGERDPSLVRTYRESEFRGSVKPGDTVVSPDGRRGRVLSVD
HCCCCCCCCEEEECCCHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEC
GGRVRVDFNHPLAGKALVYEVEVVDVLEDTVERAEGLLETMVPSVDAELELDGNTLRVRV
CCEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEE
EGDDAANPAWARAKQRFAKLMIEYDDAVEEVVFEERFTE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AVEKGDFVKIHYTGRVKDTDEVIDTTRKEVAEEHDLNVESGPVVVVVGAGMVWEPVEEA
CCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHH
LVGAEPGDELEVEVPPEKAFGERDPSLVRTYRESEFRGSVKPGDTVVSPDGRRGRVLSVD
HCCCCCCCCEEEECCCHHHCCCCCHHHHHHHHHHHHCCCCCCCCEEECCCCCCCEEEEEC
GGRVRVDFNHPLAGKALVYEVEVVDVLEDTVERAEGLLETMVPSVDAELELDGNTLRVRV
CCEEEEEECCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCEEEEEE
EGDDAANPAWARAKQRFAKLMIEYDDAVEEVVFEERFTE
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]