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The map label for this gene is CobH

Identifier: 20094632

GI number: 20094632

Start: 1190035

End: 1190634

Strand: Reverse

Name: CobH

Synonym: MK1196

Alternate gene names: NA

Gene position: 1190634-1190035 (Counterclockwise)

Preceding gene: 20094633

Following gene: 20094626

Centisome position: 70.25

GC content: 68.5

Gene sequence:

>600_bases
GTGACCCTCGGGGAGCGGACGGGTCGGGGCCGTTCGATCGCCGAGCGCAGCCTCGAGCGGTGGACCGAGAAGCTCGGTGA
GCCCGAGAACTTAGAGGACCTCCTCACTCTCCGCCTCTCCCACGCCACGTGGGACCCGTTCGTGTCGGAGACCCTGATGA
TCGAGCCCTCGGAAGAAGCCGTCACGGAGGGTCTGAAGTCCGCCGAAGTGGTAGCGGCGGACGTGGGCATGGTGGCGGCC
GGGATCCGTCGGTCGGTAGAGCGTCTCGGGTTGGAAACCGTCATCGCCTCGGAGGTCGGCGAGCGGATCCCCGAGGACAC
CGTGACCGGGGACGGTATGCGCAAGATCCTGGAGGATCACCGGAACGTGGCGGTCGTCGTCGGGAACGCCCCGACGGCCG
CGGAGAAGGTCGCCGAGTACCCGGAGTCGATCGCGGTGGCGGTCCTGTTTCCAGTGGGGATCGGTGCGATGGAGGCGAAG
CGAGCCGCGATGGACGCCGGAATCCCGGTGGTGACGAACGTCTCGGTCCGCGGTGGGACACCGCTCGCGGTGGCGGCGTT
CAACGCCCTGGCGGACTGCGTCACCGGAAACGCTCCTTGA

Upstream 100 bases:

>100_bases
CCAGGTTGGAGGAGTGGGAGCCCCCGGAGGACGAGGTCACGGGGTACTTGAGGAGGTACCGAGAGCTCGTCCGCGGGGCC
GACGAAGGGGCCGTACTGCG

Downstream 100 bases:

>100_bases
TCGTGTCGTCGTCCCGGGCCACCTGCTTCTTCATCTCCTCCCGGTACTCCTCCAGGAAGGACCGGACGTCCTCGTCCTCC
AGTGCCAGGATCTGCAAGGC

Product: precorrin isomerase

Products: hydrogenobyrinate

Alternate protein names: Precorrin-8X Methylmutase CbiC/CobH

Number of amino acids: Translated: 199; Mature: 198

Protein sequence:

>199_residues
MTLGERTGRGRSIAERSLERWTEKLGEPENLEDLLTLRLSHATWDPFVSETLMIEPSEEAVTEGLKSAEVVAADVGMVAA
GIRRSVERLGLETVIASEVGERIPEDTVTGDGMRKILEDHRNVAVVVGNAPTAAEKVAEYPESIAVAVLFPVGIGAMEAK
RAAMDAGIPVVTNVSVRGGTPLAVAAFNALADCVTGNAP

Sequences:

>Translated_199_residues
MTLGERTGRGRSIAERSLERWTEKLGEPENLEDLLTLRLSHATWDPFVSETLMIEPSEEAVTEGLKSAEVVAADVGMVAA
GIRRSVERLGLETVIASEVGERIPEDTVTGDGMRKILEDHRNVAVVVGNAPTAAEKVAEYPESIAVAVLFPVGIGAMEAK
RAAMDAGIPVVTNVSVRGGTPLAVAAFNALADCVTGNAP
>Mature_198_residues
TLGERTGRGRSIAERSLERWTEKLGEPENLEDLLTLRLSHATWDPFVSETLMIEPSEEAVTEGLKSAEVVAADVGMVAAG
IRRSVERLGLETVIASEVGERIPEDTVTGDGMRKILEDHRNVAVVVGNAPTAAEKVAEYPESIAVAVLFPVGIGAMEAKR
AAMDAGIPVVTNVSVRGGTPLAVAAFNALADCVTGNAP

Specific function: Unknown

COG id: COG2082

COG function: function code H; Precorrin isomerase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 5.4.1.2

Molecular weight: Translated: 20974; Mature: 20843

Theoretical pI: Translated: 4.38; Mature: 4.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLGERTGRGRSIAERSLERWTEKLGEPENLEDLLTLRLSHATWDPFVSETLMIEPSEEA
CCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHCCEEEECCCHHH
VTEGLKSAEVVAADVGMVAAGIRRSVERLGLETVIASEVGERIPEDTVTGDGMRKILEDH
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC
RNVAVVVGNAPTAAEKVAEYPESIAVAVLFPVGIGAMEAKRAAMDAGIPVVTNVSVRGGT
CCEEEEECCCCHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCC
PLAVAAFNALADCVTGNAP
CHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
TLGERTGRGRSIAERSLERWTEKLGEPENLEDLLTLRLSHATWDPFVSETLMIEPSEEA
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCHHHCCEEEECCCHHH
VTEGLKSAEVVAADVGMVAAGIRRSVERLGLETVIASEVGERIPEDTVTGDGMRKILEDH
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCC
RNVAVVVGNAPTAAEKVAEYPESIAVAVLFPVGIGAMEAKRAAMDAGIPVVTNVSVRGGT
CCEEEEECCCCHHHHHHHHCHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEEECCCC
PLAVAAFNALADCVTGNAP
CHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Precorrin 8X

Specific reaction: precorrin-8X = hydrogenobyrinate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA