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The map label for this gene is mshA [H]

Identifier: 20094519

GI number: 20094519

Start: 1050955

End: 1052430

Strand: Reverse

Name: mshA [H]

Synonym: MK1083

Alternate gene names: 20094519

Gene position: 1052430-1050955 (Counterclockwise)

Preceding gene: 20094520

Following gene: 20094518

Centisome position: 62.09

GC content: 57.86

Gene sequence:

>1476_bases
ATGGTGGAATTTCGGGGAAGCGGGATGTACAAACGACCCACTGTCACCGTAGTAACCGAGGCTACCTATCCCGTAGCTTT
AGGTGGGGTCACCACCTGGGTCCAGCGCCTCATCAAGTATTCACCGGATGTCGTGTTCAACGTGTTATGCATGACGGGGC
CGGAAAGAACCGAACCAGTCGTGGAAATTCCGGCAAACGTCCGGGATGTTGTAATTCAGGAGATCGTCCCGAAGGGGAAC
AAACTGCGCCGGTGGCTCGACAGGATAACTCCCACACACCGCCTCAGGTGGTCGACCGCAGCGAAAACGCTCCGGGCCAC
CTTCGAGAGGATGGTGGAAGGTGAACCACTTTCGGAGCCAATGCTGAAGGAGCTGTGGAAGGTTTCCAAGTCGCCCACGA
GCGTACTCGCCAGCTCCACGATGTACGAGCTCGCACGATACGTTCACTACCTAGCCTCCCAGTACGAGGACAAGTGCGAG
AATAACCCGTTCAGCGACGTGTTCTGGGTAGCCGTGAACATAGCATCCTTCGTGCTAGGGGCGGCCGCCGGCGCTAGACG
ACTACCGAACTGTGACGTCGCGCACGCCCAGAACTCGGGAGTATGCGGGTTCCTGTGCTCGGTCGCGAAGGCGGTACGGA
ATGTCCCCTTTATCATCACCGAGCACGGGATACTGCTTAGGGAGCTCGACACGCGACTGGAGGGGTACGGGAGGACGACA
CGCGAGCTTTTCAAGGAGTGCTTCCGCTCGATGATGCTCACGTCGTACGAGCAGTGCGAGGAGATAATAGAAATCTCGGA
CTACCACGCGGAGCTGGCCCTGGAGCAGGGAGCTCCTGAGGATAAAATCAAAGTCGTTTACTCGGGAATAGAGACCTGGA
AGTACTCTCCCGGCGACCTGGAGAGGAAGTACAACGAGCCGGAAGTGCTCGAGGTCGGTACGATCACGAGGATCGAACGC
GTCAAGGGTATCGACGTACTTATCGAGATCGCGGCCCGCACCGTCGAGCACATAGGCAATGTCGTGTTCCACGTGGTAGG
CCCAGTGGAAGACGAGGCGTACTACGAGGAGTGCCGGAAACTCGTGAAGGAGTACGGCCTGGAAGACATCGTGAGGTTCC
ACGGTCCCTGCACTCCAGACGAGGTAGTCAAGTGGCTTCGTAGGTTCCACATCTTCCTCCTACCGAGCCGCTCGGAAGGA
CTGCCAATGGCACTCCTCGAGGCGATGAGCTGTGGATGCCCGGTAGTAGCCTCCGAGGTCGGCGCAGTGCCGTACATAGT
CGACAGGAACTTCGGTCGCACCTTCCGATCCGAGGACGCGGACGAAGCCGCCAGGCACCTGGTACGCCTACTCTACGATC
CCGAGTTAATGTTCGAGATGGCACATCATGCCACCAAACGCGCCAAACAGTACGATGTAATGCGCATGTGTCATGACTAC
TTCCGGGAGTACTGTAAATACGCCAGGGGTGACTGA

Upstream 100 bases:

>100_bases
ATGGGGCTACACCGGACGGGGGTGACTCCTATCACTGGGGTTATTACCTAAAGAAACCGAAAGGAAGGAAGCGTGGACCC
AGCTCCAGGCCGACCACTCT

Downstream 100 bases:

>100_bases
ATTGGGCGCAATATCTGACACATTAGTGGCGATAATCCGCTCAGTAGGTAGAGCCGCCAGTAACCCGGTCGTACTCATAA
AAATCGTCTTAGGCGCTTCC

Product: glycosyltransferase

Products: NA

Alternate protein names: N-acetylglucosamine-inositol-phosphate N-acetylglucosaminyltransferase; GlcNAc-Ins-P N-acetylglucosaminyltransferase [H]

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MVEFRGSGMYKRPTVTVVTEATYPVALGGVTTWVQRLIKYSPDVVFNVLCMTGPERTEPVVEIPANVRDVVIQEIVPKGN
KLRRWLDRITPTHRLRWSTAAKTLRATFERMVEGEPLSEPMLKELWKVSKSPTSVLASSTMYELARYVHYLASQYEDKCE
NNPFSDVFWVAVNIASFVLGAAAGARRLPNCDVAHAQNSGVCGFLCSVAKAVRNVPFIITEHGILLRELDTRLEGYGRTT
RELFKECFRSMMLTSYEQCEEIIEISDYHAELALEQGAPEDKIKVVYSGIETWKYSPGDLERKYNEPEVLEVGTITRIER
VKGIDVLIEIAARTVEHIGNVVFHVVGPVEDEAYYEECRKLVKEYGLEDIVRFHGPCTPDEVVKWLRRFHIFLLPSRSEG
LPMALLEAMSCGCPVVASEVGAVPYIVDRNFGRTFRSEDADEAARHLVRLLYDPELMFEMAHHATKRAKQYDVMRMCHDY
FREYCKYARGD

Sequences:

>Translated_491_residues
MVEFRGSGMYKRPTVTVVTEATYPVALGGVTTWVQRLIKYSPDVVFNVLCMTGPERTEPVVEIPANVRDVVIQEIVPKGN
KLRRWLDRITPTHRLRWSTAAKTLRATFERMVEGEPLSEPMLKELWKVSKSPTSVLASSTMYELARYVHYLASQYEDKCE
NNPFSDVFWVAVNIASFVLGAAAGARRLPNCDVAHAQNSGVCGFLCSVAKAVRNVPFIITEHGILLRELDTRLEGYGRTT
RELFKECFRSMMLTSYEQCEEIIEISDYHAELALEQGAPEDKIKVVYSGIETWKYSPGDLERKYNEPEVLEVGTITRIER
VKGIDVLIEIAARTVEHIGNVVFHVVGPVEDEAYYEECRKLVKEYGLEDIVRFHGPCTPDEVVKWLRRFHIFLLPSRSEG
LPMALLEAMSCGCPVVASEVGAVPYIVDRNFGRTFRSEDADEAARHLVRLLYDPELMFEMAHHATKRAKQYDVMRMCHDY
FREYCKYARGD
>Mature_491_residues
MVEFRGSGMYKRPTVTVVTEATYPVALGGVTTWVQRLIKYSPDVVFNVLCMTGPERTEPVVEIPANVRDVVIQEIVPKGN
KLRRWLDRITPTHRLRWSTAAKTLRATFERMVEGEPLSEPMLKELWKVSKSPTSVLASSTMYELARYVHYLASQYEDKCE
NNPFSDVFWVAVNIASFVLGAAAGARRLPNCDVAHAQNSGVCGFLCSVAKAVRNVPFIITEHGILLRELDTRLEGYGRTT
RELFKECFRSMMLTSYEQCEEIIEISDYHAELALEQGAPEDKIKVVYSGIETWKYSPGDLERKYNEPEVLEVGTITRIER
VKGIDVLIEIAARTVEHIGNVVFHVVGPVEDEAYYEECRKLVKEYGLEDIVRFHGPCTPDEVVKWLRRFHIFLLPSRSEG
LPMALLEAMSCGCPVVASEVGAVPYIVDRNFGRTFRSEDADEAARHLVRLLYDPELMFEMAHHATKRAKQYDVMRMCHDY
FREYCKYARGD

Specific function: Catalyzes the transfer of a N-acetyl-glucosamine moiety to 1D-myo-inositol 3-phosphate to produce 1D-myo-inositol 2- acetamido-2-deoxy-glucopyranoside 3-phosphate in the mycothiol biosynthesis pathway [H]

COG id: COG0438

COG function: function code M; Glycosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family. MshA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788357, Length=255, Percent_Identity=29.0196078431373, Blast_Score=79, Evalue=6e-16,
Organism=Drosophila melanogaster, GI24654571, Length=152, Percent_Identity=28.2894736842105, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296
- InterPro:   IPR017814 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.250 [H]

Molecular weight: Translated: 56017; Mature: 56017

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVEFRGSGMYKRPTVTVVTEATYPVALGGVTTWVQRLIKYSPDVVFNVLCMTGPERTEPV
CCEECCCCCCCCCCEEEEECCCCCCHHCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCE
VEIPANVRDVVIQEIVPKGNKLRRWLDRITPTHRLRWSTAAKTLRATFERMVEGEPLSEP
EECCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
MLKELWKVSKSPTSVLASSTMYELARYVHYLASQYEDKCENNPFSDVFWVAVNIASFVLG
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AAAGARRLPNCDVAHAQNSGVCGFLCSVAKAVRNVPFIITEHGILLRELDTRLEGYGRTT
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCHH
RELFKECFRSMMLTSYEQCEEIIEISDYHAELALEQGAPEDKIKVVYSGIETWKYSPGDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCH
ERKYNEPEVLEVGTITRIERVKGIDVLIEIAARTVEHIGNVVFHVVGPVEDEAYYEECRK
HHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LVKEYGLEDIVRFHGPCTPDEVVKWLRRFHIFLLPSRSEGLPMALLEAMSCGCPVVASEV
HHHHHCHHHHHHHCCCCCHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHCCCCHHHHHH
GAVPYIVDRNFGRTFRSEDADEAARHLVRLLYDPELMFEMAHHATKRAKQYDVMRMCHDY
CCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FREYCKYARGD
HHHHHHHCCCC
>Mature Secondary Structure
MVEFRGSGMYKRPTVTVVTEATYPVALGGVTTWVQRLIKYSPDVVFNVLCMTGPERTEPV
CCEECCCCCCCCCCEEEEECCCCCCHHCHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCE
VEIPANVRDVVIQEIVPKGNKLRRWLDRITPTHRLRWSTAAKTLRATFERMVEGEPLSEP
EECCCHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCH
MLKELWKVSKSPTSVLASSTMYELARYVHYLASQYEDKCENNPFSDVFWVAVNIASFVLG
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
AAAGARRLPNCDVAHAQNSGVCGFLCSVAKAVRNVPFIITEHGILLRELDTRLEGYGRTT
HHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCCCHH
RELFKECFRSMMLTSYEQCEEIIEISDYHAELALEQGAPEDKIKVVYSGIETWKYSPGDL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCH
ERKYNEPEVLEVGTITRIERVKGIDVLIEIAARTVEHIGNVVFHVVGPVEDEAYYEECRK
HHCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
LVKEYGLEDIVRFHGPCTPDEVVKWLRRFHIFLLPSRSEGLPMALLEAMSCGCPVVASEV
HHHHHCHHHHHHHCCCCCHHHHHHHHHHHHEEEECCCCCCCCHHHHHHHHCCCCHHHHHH
GAVPYIVDRNFGRTFRSEDADEAARHLVRLLYDPELMFEMAHHATKRAKQYDVMRMCHDY
CCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHH
FREYCKYARGD
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA