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The map label for this gene is ThrC [H]

Identifier: 20094410

GI number: 20094410

Start: 934272

End: 935483

Strand: Direct

Name: ThrC [H]

Synonym: MK0974

Alternate gene names: 20094410

Gene position: 934272-935483 (Clockwise)

Preceding gene: 20094409

Following gene: 20094412

Centisome position: 55.12

GC content: 63.04

Gene sequence:

>1212_bases
TTGCATTACGTCCTGGAGTGTGTTGAATGCGGTTCGGAGTTCGATGATGACTCACTGGTACGGTGCCCCGAGTGCGGAGG
ACTCCTGGAGGTGGCACTGCGCTACGACGAAATCGAGGTGAGTCGGTCGACGTTCGAGGGTCGTCGCCTCGGCGTATGGG
CCTTCCGGGAGCTCCTACCAGTGAACACGGACGATCCCGTCACGATGTCCGAGGGCGGTACGGGCTTACACCCGTGTCCG
AGACTGGGCGAGGAGCTCGGTGTTAGGGAGCTGTTCGTGAAGAACGAGGGCGAGAACCCCACGGGCTCCTTCAAGGATCG
GGGAATGACCGTGGGAGTTACCAAGGCCGTGGAGCTCGGTGCGGAGGTCGTCGCATGTGCCTCGACGGGCAACACATCGG
CCTCGTTGGCCGCCTACGCCGCCCGCGCGGGCCTTACGTGTGCCGTCCTCCTTCCGGCCGGTAAGGTGGCCCTAGGCAAA
CTCGCTCAAGCCCTCTTCCACGGTGCCCGCGTGATTCCAGTGAACGGCAACTTCGACGACGCCTTGGATGTCGTGAAGAA
GCTGGCCGATGAGGGCATCGTGTACATTCTAAACTCCGTGAACCCGTTCCGCCTCTCCGGTCAGCGTACCATCGCGTACG
AGATCTGCTTGCAGTTGGACTGGGAGGTCCCCGACGCGGTCGTCGTGCCGGTCGGTAACGCGGGTAACATCAGCGCGATC
TGGCAGGGGTTCCTCGATCTCTACAGGCTGGGAATCATCGACGAGCTCCCGAGGATGTACGGAGTACAGGCGGAGGGTGC
TCGACCGATCGTCGAGGCGATTCGGCGGGGCAAGGAGGACATCGAACCGGATCCCGAGCCCGAAACCGTCGCCACCGCGA
TCCGCATCGGTAACCCAGTGAACGCCATCAAGGCTCTCCGTGCCATCCGGTGTTCGGGCGGCTGGGCCGTAGAGGTCTCC
GACGAGGAAATACTCTCGGCGCAGCGTGAGCTCGCAACGCGGGAGGGGATCTTCGTGGAGCCGGCGAGTGCCGCCTCGAT
AGCGGGACTCAGGAAGTTCGTGGAGGAGGGTGAGATCGACGCCGACGAGCGGGTGGTCTGCGTGACCACCGGACACGGTT
TGAAGGATCCGGAGACGGTCATGGAAGTGTGTGAGCTGCCTGAACCCGTGGAACCGGATCCCGAGACCATACAGCGTTTA
ATCGCCGAGTGA

Upstream 100 bases:

>100_bases
CGGTGCAGCGCTGATCTTCAGGTGTCGGCGCTGACGCCCCTCGATCATTTTATATCTTCCGAATCGTTACTCGTCTCAAA
ACGTTCGGGGGAGTACGGGG

Downstream 100 bases:

>100_bases
CCTCTACGGCTCCCTCGGATGTCAGTCTTACTCACAGGGCAAGGTCGCTCCGCGATCCTTCCAACGTCGGAAAACGTTAT
GAACACGATAACGAATCACG

Product: threonine synthase

Products: NA

Alternate protein names: TS [H]

Number of amino acids: Translated: 403; Mature: 403

Protein sequence:

>403_residues
MHYVLECVECGSEFDDDSLVRCPECGGLLEVALRYDEIEVSRSTFEGRRLGVWAFRELLPVNTDDPVTMSEGGTGLHPCP
RLGEELGVRELFVKNEGENPTGSFKDRGMTVGVTKAVELGAEVVACASTGNTSASLAAYAARAGLTCAVLLPAGKVALGK
LAQALFHGARVIPVNGNFDDALDVVKKLADEGIVYILNSVNPFRLSGQRTIAYEICLQLDWEVPDAVVVPVGNAGNISAI
WQGFLDLYRLGIIDELPRMYGVQAEGARPIVEAIRRGKEDIEPDPEPETVATAIRIGNPVNAIKALRAIRCSGGWAVEVS
DEEILSAQRELATREGIFVEPASAASIAGLRKFVEEGEIDADERVVCVTTGHGLKDPETVMEVCELPEPVEPDPETIQRL
IAE

Sequences:

>Translated_403_residues
MHYVLECVECGSEFDDDSLVRCPECGGLLEVALRYDEIEVSRSTFEGRRLGVWAFRELLPVNTDDPVTMSEGGTGLHPCP
RLGEELGVRELFVKNEGENPTGSFKDRGMTVGVTKAVELGAEVVACASTGNTSASLAAYAARAGLTCAVLLPAGKVALGK
LAQALFHGARVIPVNGNFDDALDVVKKLADEGIVYILNSVNPFRLSGQRTIAYEICLQLDWEVPDAVVVPVGNAGNISAI
WQGFLDLYRLGIIDELPRMYGVQAEGARPIVEAIRRGKEDIEPDPEPETVATAIRIGNPVNAIKALRAIRCSGGWAVEVS
DEEILSAQRELATREGIFVEPASAASIAGLRKFVEEGEIDADERVVCVTTGHGLKDPETVMEVCELPEPVEPDPETIQRL
IAE
>Mature_403_residues
MHYVLECVECGSEFDDDSLVRCPECGGLLEVALRYDEIEVSRSTFEGRRLGVWAFRELLPVNTDDPVTMSEGGTGLHPCP
RLGEELGVRELFVKNEGENPTGSFKDRGMTVGVTKAVELGAEVVACASTGNTSASLAAYAARAGLTCAVLLPAGKVALGK
LAQALFHGARVIPVNGNFDDALDVVKKLADEGIVYILNSVNPFRLSGQRTIAYEICLQLDWEVPDAVVVPVGNAGNISAI
WQGFLDLYRLGIIDELPRMYGVQAEGARPIVEAIRRGKEDIEPDPEPETVATAIRIGNPVNAIKALRAIRCSGGWAVEVS
DEEILSAQRELATREGIFVEPASAASIAGLRKFVEEGEIDADERVVCVTTGHGLKDPETVMEVCELPEPVEPDPETIQRL
IAE

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 43383; Mature: 43383

Theoretical pI: Translated: 4.26; Mature: 4.26

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYVLECVECGSEFDDDSLVRCPECGGLLEVALRYDEIEVSRSTFEGRRLGVWAFRELLP
CHHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHEECHHHCCCCEEHHHHHHHHCC
VNTDDPVTMSEGGTGLHPCPRLGEELGVRELFVKNEGENPTGSFKDRGMTVGVTKAVELG
CCCCCCEEECCCCCCCCCCHHHHHHCCHHHEEEECCCCCCCCCCCCCCEEEEHHHHHHHC
AEVVACASTGNTSASLAAYAARAGLTCAVLLPAGKVALGKLAQALFHGARVIPVNGNFDD
CCEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCHH
ALDVVKKLADEGIVYILNSVNPFRLSGQRTIAYEICLQLDWEVPDAVVVPVGNAGNISAI
HHHHHHHHHCCCEEEEECCCCCEEECCCEEEEEEEEEEECCCCCCEEEEECCCCCCHHHH
WQGFLDLYRLGIIDELPRMYGVQAEGARPIVEAIRRGKEDIEPDPEPETVATAIRIGNPV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHCCCCCCCHHHHHHHHCCCHH
NAIKALRAIRCSGGWAVEVSDEEILSAQRELATREGIFVEPASAASIAGLRKFVEEGEID
HHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHCCCCC
ADERVVCVTTGHGLKDPETVMEVCELPEPVEPDPETIQRLIAE
CCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCC
>Mature Secondary Structure
MHYVLECVECGSEFDDDSLVRCPECGGLLEVALRYDEIEVSRSTFEGRRLGVWAFRELLP
CHHHHHHHHCCCCCCCCCCEECCCCCCHHHHHHHHHHHEECHHHCCCCEEHHHHHHHHCC
VNTDDPVTMSEGGTGLHPCPRLGEELGVRELFVKNEGENPTGSFKDRGMTVGVTKAVELG
CCCCCCEEECCCCCCCCCCHHHHHHCCHHHEEEECCCCCCCCCCCCCCEEEEHHHHHHHC
AEVVACASTGNTSASLAAYAARAGLTCAVLLPAGKVALGKLAQALFHGARVIPVNGNFDD
CCEEEEECCCCCCHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCHH
ALDVVKKLADEGIVYILNSVNPFRLSGQRTIAYEICLQLDWEVPDAVVVPVGNAGNISAI
HHHHHHHHHCCCEEEEECCCCCEEECCCEEEEEEEEEEECCCCCCEEEEECCCCCCHHHH
WQGFLDLYRLGIIDELPRMYGVQAEGARPIVEAIRRGKEDIEPDPEPETVATAIRIGNPV
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCHHHCCCCCCCHHHHHHHHCCCHH
NAIKALRAIRCSGGWAVEVSDEEILSAQRELATREGIFVEPASAASIAGLRKFVEEGEID
HHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHCCCEECCCCHHHHHHHHHHHHCCCCC
ADERVVCVTTGHGLKDPETVMEVCELPEPVEPDPETIQRLIAE
CCCEEEEEECCCCCCCHHHHHHHHCCCCCCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]