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The map label for this gene is CdhD

Identifier: 20094159

GI number: 20094159

Start: 689798

End: 691000

Strand: Direct

Name: CdhD

Synonym: MK0722

Alternate gene names: 20094159

Gene position: 689798-691000 (Clockwise)

Preceding gene: 20094158

Following gene: 20094160

Centisome position: 40.7

GC content: 60.02

Gene sequence:

>1203_bases
ATGGCTGAGGATAAGGGCGTGAAGAACATGCTTGAGCACCTCGTGAAGAACCTATTAGTGGAAGATGTTGAGGAGATCGA
GCTGCGGAACGTGACGATCGAGTTAGACGAGCTGGAGCTGGACCTCAAAACCGTGGCCCAAACTCTGCCGGTTGAGATCT
GGGAACGCATACTCAAGCCTGAGGTTGAAGAGAAGGAGAGAGAGGTCGAGGTCCCGGAATACGAACCACCGGTTGAGGAG
TACGAAGGCTGTGTGGCCGAGGTGCAGATCGGGGCGACGCGGTCCGACGGCGGTTCTCGGGATCGGGTCGTCGTCCTGGG
TGGTGAGCGCGCCTACTTCCCGTTCGAAGAACCACGACCGAACCCTCCCGTGGTCACGTTCGACGTGTTCGACACCCCGG
ATGTGGGTATCCCCGGACCTATTCGGGAGGAGCTGGGCGACGTCATCGAAGACCCCGTGGACTGGGCAAGAACTGTCGTC
AAGCGCTACGGCGTCGATATCGTCACCGTCCATCTGGTCAGTACGTCCCCCAAGCTCCATGATGCTCCTGTCGAGGAGGC
TATGGAGACACTGGAGGACATCCTCGATGCCGTGAAGGTCCCGATCATCGTGGGCGGATCCGGCGACCCCGAGAAGGATG
TGGAGGTGTTCGTGAAGGCGGCCGAAGTCTGCGAGGGAGAGCGGGTGATGCTATCCTCGATCAACGAGGACATGGACTTC
GAGCGGGTGGTTGAGGCGGCCAAAGAACACGGTCACGTGGTACTGACCTTCGCCCCGGTCGATGTGAACCTCATGAAGTC
CCTGAATAAGAAAGTACTGAATAGAGGCCTCTCGAAGGAAGACGTCGTCATGGACCCGACGACCTGCGCTCTGGGTTACG
GTATCGAGTACACGATCGACGTTATGACCAGGATCAGGCTCGCCGCGCTGAAGGGTGATGAACACCTGCAGATGCCGATC
TCCAGCGGTTCCACCAACGCGTGGGCCGCGCGGGAGGCTTGGATGAAGGAGGAATCTTGGGGACCGCGTGAGTACCGCGG
ACCGCTGTGGGAGGCGGTAACGGCGACCACGGTGGCACTCTGCGGTGCCGACCTGTTGATGATGTTCCACCCGTGGGCCG
TGCAAGTGGTTATGGAGGCTATGGAGTACATGGCCGAAGGACGCGTCACCGGAGACGCGTACGTGACCGACGTGATCGCC
TGA

Upstream 100 bases:

>100_bases
CTCGAGCTTCATGGTCGCCCTCTGACCGAACTCCCACCGGACGCCAAGGTCCGCCGTGATATGCGCGCCGTGCTTACGCG
GGTGGGGGTGCTCCTATCCG

Downstream 100 bases:

>100_bases
GGGGGAGACGCTCGTGGCCCAGCTCAGCGCGATGGACGTGTACAACCTGCTACCCAAGGCCAACTGCGGGGCGTGTGGCT
GCAAGACCTGCATGGAATTC

Product: acetyl-CoA decarbonylase/synthase complex subunit delta

Products: CO2; AH2

Alternate protein names: ACDS complex subunit delta; Corrinoid/iron-sulfur component small subunit

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MAEDKGVKNMLEHLVKNLLVEDVEEIELRNVTIELDELELDLKTVAQTLPVEIWERILKPEVEEKEREVEVPEYEPPVEE
YEGCVAEVQIGATRSDGGSRDRVVVLGGERAYFPFEEPRPNPPVVTFDVFDTPDVGIPGPIREELGDVIEDPVDWARTVV
KRYGVDIVTVHLVSTSPKLHDAPVEEAMETLEDILDAVKVPIIVGGSGDPEKDVEVFVKAAEVCEGERVMLSSINEDMDF
ERVVEAAKEHGHVVLTFAPVDVNLMKSLNKKVLNRGLSKEDVVMDPTTCALGYGIEYTIDVMTRIRLAALKGDEHLQMPI
SSGSTNAWAAREAWMKEESWGPREYRGPLWEAVTATTVALCGADLLMMFHPWAVQVVMEAMEYMAEGRVTGDAYVTDVIA

Sequences:

>Translated_400_residues
MAEDKGVKNMLEHLVKNLLVEDVEEIELRNVTIELDELELDLKTVAQTLPVEIWERILKPEVEEKEREVEVPEYEPPVEE
YEGCVAEVQIGATRSDGGSRDRVVVLGGERAYFPFEEPRPNPPVVTFDVFDTPDVGIPGPIREELGDVIEDPVDWARTVV
KRYGVDIVTVHLVSTSPKLHDAPVEEAMETLEDILDAVKVPIIVGGSGDPEKDVEVFVKAAEVCEGERVMLSSINEDMDF
ERVVEAAKEHGHVVLTFAPVDVNLMKSLNKKVLNRGLSKEDVVMDPTTCALGYGIEYTIDVMTRIRLAALKGDEHLQMPI
SSGSTNAWAAREAWMKEESWGPREYRGPLWEAVTATTVALCGADLLMMFHPWAVQVVMEAMEYMAEGRVTGDAYVTDVIA
>Mature_399_residues
AEDKGVKNMLEHLVKNLLVEDVEEIELRNVTIELDELELDLKTVAQTLPVEIWERILKPEVEEKEREVEVPEYEPPVEEY
EGCVAEVQIGATRSDGGSRDRVVVLGGERAYFPFEEPRPNPPVVTFDVFDTPDVGIPGPIREELGDVIEDPVDWARTVVK
RYGVDIVTVHLVSTSPKLHDAPVEEAMETLEDILDAVKVPIIVGGSGDPEKDVEVFVKAAEVCEGERVMLSSINEDMDFE
RVVEAAKEHGHVVLTFAPVDVNLMKSLNKKVLNRGLSKEDVVMDPTTCALGYGIEYTIDVMTRIRLAALKGDEHLQMPIS
SGSTNAWAAREAWMKEESWGPREYRGPLWEAVTATTVALCGADLLMMFHPWAVQVVMEAMEYMAEGRVTGDAYVTDVIA

Specific function: Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably maintains the overall quaternary structure of the ACDS complex

COG id: COG2069

COG function: function code C; CO dehydrogenase/acetyl-CoA synthase delta subunit (corrinoid Fe-S protein)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CdhD family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDD_METKA (Q8TXF2)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614006.1
- ProteinModelPortal:   Q8TXF2
- GeneID:   1476823
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0722
- NMPDR:   fig|190192.1.peg.719
- HOGENOM:   HBG456967
- OMA:   IVMDPTT
- ProtClustDB:   PRK04452
- BioCyc:   MKAN190192:MK0722-MONOMER
- HAMAP:   MF_01135
- InterPro:   IPR016041
- InterPro:   IPR004486
- InterPro:   IPR011005
- InterPro:   IPR000489
- Gene3D:   G3DSA:3.20.20.20
- TIGRFAMs:   TIGR00381

Pfam domain/function: PF03599 CdhD; SSF51717 DHP_synth_like

EC number: 1.2.99.2

Molecular weight: Translated: 44543; Mature: 44412

Theoretical pI: Translated: 4.13; Mature: 4.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEDKGVKNMLEHLVKNLLVEDVEEIELRNVTIELDELELDLKTVAQTLPVEIWERILKP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHHHHCCHHHHHHHHCC
EVEEKEREVEVPEYEPPVEEYEGCVAEVQIGATRSDGGSRDRVVVLGGERAYFPFEEPRP
CHHHHHHCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCCCEEEEEECCEEECCCCCCCC
NPPVVTFDVFDTPDVGIPGPIREELGDVIEDPVDWARTVVKRYGVDIVTVHLVSTSPKLH
CCCEEEEECCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHCCEEEEEEEEECCCCCC
DAPVEEAMETLEDILDAVKVPIIVGGSGDPEKDVEVFVKAAEVCEGERVMLSSINEDMDF
CCCHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCH
ERVVEAAKEHGHVVLTFAPVDVNLMKSLNKKVLNRGLSKEDVVMDPTTCALGYGIEYTID
HHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEECCCHHHHCCCCHHHHH
VMTRIRLAALKGDEHLQMPISSGSTNAWAAREAWMKEESWGPREYRGPLWEAVTATTVAL
HHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHH
CGADLLMMFHPWAVQVVMEAMEYMAEGRVTGDAYVTDVIA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCC
>Mature Secondary Structure 
AEDKGVKNMLEHLVKNLLVEDVEEIELRNVTIELDELELDLKTVAQTLPVEIWERILKP
CCCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEEHHHHHHHHHHHHHCCHHHHHHHHCC
EVEEKEREVEVPEYEPPVEEYEGCVAEVQIGATRSDGGSRDRVVVLGGERAYFPFEEPRP
CHHHHHHCCCCCCCCCCHHHHCCCEEEEEECCCCCCCCCCCEEEEEECCEEECCCCCCCC
NPPVVTFDVFDTPDVGIPGPIREELGDVIEDPVDWARTVVKRYGVDIVTVHLVSTSPKLH
CCCEEEEECCCCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHCCEEEEEEEEECCCCCC
DAPVEEAMETLEDILDAVKVPIIVGGSGDPEKDVEVFVKAAEVCEGERVMLSSINEDMDF
CCCHHHHHHHHHHHHHHHHCCEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHCCCCCCH
ERVVEAAKEHGHVVLTFAPVDVNLMKSLNKKVLNRGLSKEDVVMDPTTCALGYGIEYTID
HHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCEEECCCHHHHCCCCHHHHH
VMTRIRLAALKGDEHLQMPISSGSTNAWAAREAWMKEESWGPREYRGPLWEAVTATTVAL
HHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHH
CGADLLMMFHPWAVQVVMEAMEYMAEGRVTGDAYVTDVIA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CO; H2O; A

Specific reaction: CO + H2O + A = CO2 + AH2

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014