Click here to switch to the map view.

The map label for this gene is CdhA_1

Identifier: 20094154

GI number: 20094154

Start: 682947

End: 685229

Strand: Direct

Name: CdhA_1

Synonym: MK0717

Alternate gene names: 20094154

Gene position: 682947-685229 (Clockwise)

Preceding gene: 20094152

Following gene: 20094155

Centisome position: 40.29

GC content: 58.21

Gene sequence:

>2283_bases
ATGTCCCCGTTCGAGCTCGAGTTCGAGGGGTTGAAAGTCCAGATAGGCTCCATCGAGGGCTTCGAGCCCAGGGGAGAGGG
GCCGCTACCCTGCCCGACCGTCTCAGATCTCGCGGACTGGGATAGAAAGCTTTTCGCCCGGTATCGGGTGATCGCGTTTC
CCATCTGTGACATGTGTTGTATGTGCACCTACGGCCGTTGTAATCTGGCCGAGGGCAGGCGAGGAGCTTGTGGAATAGAT
ATCCGCTCCAACACGGCCCGGTTCACCGCGCTCAAGACCTGCATCGGTGCGGCCTGCCACGCGGCCCACGCACGCCACCT
CGTCGAGTACATCTTGGAAAAGCTCGGTGACGTTGAGATCGATCTGGGCTCCGAGGTCGACGTGATGACTCCGATATTCG
AGACGCTCGTGGGATTCAAGCCGAAGACGGTTTCGGACCTCGAGAAGGGGCTTGAGTACATCGAGCGCGAGCTCACGAAG
GTCCTATCGTCCGTGCATGTGGGTCAGGAGATGGATCCCCACGATTACGAGTCCAAGGCCCTCCACGCAGGCATGATCGA
CAACCTCGCGCTCGAGATCGCCGACGTGGCGCAGATCGCGGCCTTCGATATGCCGAAGGGTGAGGCACCCCTCGTGGAGT
TCGGACCGTTCGCGGCGGACGACTCCAAGCCGTGTATACTGCTCGTAGGTCACAACGTGGCTCCCGGCACCGAAGTTCTC
GATTACCTGGAAGAGCGCGGTCTCGACGAGGAGGTCGAGGTTCTCGGGATCTGCTGCACGGCCTGGGACGTCAGCCGTGT
GGACGACCGTTCGAAGGTGATCGGGCCCCTATCGAGGCAGCTCCACTACGTGAGGATGGGTATCGCGGACGTGGTAGTGC
TCGACGAGCAGTGCATCCGCGCGGACATCGTGGAGGAAGCCAACGAGGTGGGATCTAGAGTCATCGCCACGCGCGATCTA
GTGATGGCCGGACTGCCGGACGTCACGGACGAGCCCACGGAGAAGATCATCGAGAAGATGGTATCCGGGGAGTGGATGGG
GGTCTTCATCGAGGACCTGGAGAAGGCCGCCGAAGTCGCGGTCGAGGTCGCGATAAGGGTTCACGAGCGGCGGAAGAAAG
AGATCCCACAACCTGACCCGAAGAAACTCCAGAAGGAGGCCAAGCGCTGTTTGGGATGTGGCGACTGTGAACGGGTATGC
CCCAACGACTTACCGATCGTCGAGGCTATGGAGAGGGCGGCGAACGGCGACTTCGAGGGACTGGCCGACTTGTTCGACCG
GTGCGTGGGTTGTGCCCGGTGCGAGTCCGAGTGTCCGACGAAGCTCCGTGTTATGAACATGATCGAGGACGCCTGGAGAC
TGAGGACTAAAGAGGAAAAGTACAAAGTGCGTACCGGCCGCGGTCCGATTAAGGATGTCGAGATACGGCAGGTAGGAGGT
CCTATCGTGATGGGGGATATTCCGGGTGTAGTTGCCTTCGTAGCGTGTCCGAACTATCCTGATGATGTGAAGCAAGTGGG
TAAAATGGTGGAAGAACTTCTGGAACGAAATTACATCGTACTGACTTCGGGTTGCACTGCGATGGCACTCGGTATGTACA
CGGATGAGGATGGTAAGACCTTGTATGAAAAGTACGAAGATAGGTTCGATGCAGGTTGTCTCGTGAACACTGGCTCCTGT
GTCTCGAACGCTCACATACTCGGCGCATGTATTAAAATTGCCGCCATCTTCGCGAAGAAGCCACTTAAAGGGAACTTCAA
GGAGATTGCTGATTACATCCTCAACAGGATCGGAGCTTGTGGTGTACTGTGGGGTACGATGAGTCAGAAGGCCCTCGCGA
TATCCACGGGCTTCACGCGGTGGGGTATTCCGATAGTTTACGGTCCGGCTGGTCTCAAATATCAAACCTTATACATCGGC
GACCTCGACGGGGATTGGACGGTGTACGACGCACGCACGGGTAAGGAGTGCAAAGAGTACTGTCCCATTCACCTGAAGTA
CGCAGCGGAGGACTGGAGGGAGGCGCTCGTTCAGGCGGTGAAGCTCTGCATCCGCCCCAACGATACACCGCAGGGACGAC
AGACGAAGCTTCAGAACTACATCGAGCTGTACAAGGAGTTCTACAACGAGCTCCCACCGGACCTGCCACTGTACGTCCGT
GACAAGAACGACGTTCCGATCACCCTGCGCGACGAGGTGATGGAGTACCTGGAGGAGGTCGGTTGGAAGCCCCGGAAGGG
TATCACCGAGCCGACCTTACTGGAGGAGAACGTGCGGGGTTAA

Upstream 100 bases:

>100_bases
CGGCAAAAAACATTATAAGTACAGCGGGGACGAGGTGGTGCACGGTTCGGGTTCCCCCGAAACTGGTTTCGGGAAAGCCG
TAAGGTCGGGTGGTTAGGGA

Downstream 100 bases:

>100_bases
GCCCGTTGCCGCTACCGAGGGACCCCACACTGATTTACACGGACAAGGCCGAGGTGGCCCGAGCGCCGGTGCTCAAGATG
GTGTTCCGTCGCGCTAACGA

Product: acetyl-CoA decarbonylase/synthase complex subunit alpha

Products: NA

Alternate protein names: ACDS complex subunit alpha 1; ACDS complex carbon monoxide dehydrogenase 1; ACDS CODH 1

Number of amino acids: Translated: 760; Mature: 759

Protein sequence:

>760_residues
MSPFELEFEGLKVQIGSIEGFEPRGEGPLPCPTVSDLADWDRKLFARYRVIAFPICDMCCMCTYGRCNLAEGRRGACGID
IRSNTARFTALKTCIGAACHAAHARHLVEYILEKLGDVEIDLGSEVDVMTPIFETLVGFKPKTVSDLEKGLEYIERELTK
VLSSVHVGQEMDPHDYESKALHAGMIDNLALEIADVAQIAAFDMPKGEAPLVEFGPFAADDSKPCILLVGHNVAPGTEVL
DYLEERGLDEEVEVLGICCTAWDVSRVDDRSKVIGPLSRQLHYVRMGIADVVVLDEQCIRADIVEEANEVGSRVIATRDL
VMAGLPDVTDEPTEKIIEKMVSGEWMGVFIEDLEKAAEVAVEVAIRVHERRKKEIPQPDPKKLQKEAKRCLGCGDCERVC
PNDLPIVEAMERAANGDFEGLADLFDRCVGCARCESECPTKLRVMNMIEDAWRLRTKEEKYKVRTGRGPIKDVEIRQVGG
PIVMGDIPGVVAFVACPNYPDDVKQVGKMVEELLERNYIVLTSGCTAMALGMYTDEDGKTLYEKYEDRFDAGCLVNTGSC
VSNAHILGACIKIAAIFAKKPLKGNFKEIADYILNRIGACGVLWGTMSQKALAISTGFTRWGIPIVYGPAGLKYQTLYIG
DLDGDWTVYDARTGKECKEYCPIHLKYAAEDWREALVQAVKLCIRPNDTPQGRQTKLQNYIELYKEFYNELPPDLPLYVR
DKNDVPITLRDEVMEYLEEVGWKPRKGITEPTLLEENVRG

Sequences:

>Translated_760_residues
MSPFELEFEGLKVQIGSIEGFEPRGEGPLPCPTVSDLADWDRKLFARYRVIAFPICDMCCMCTYGRCNLAEGRRGACGID
IRSNTARFTALKTCIGAACHAAHARHLVEYILEKLGDVEIDLGSEVDVMTPIFETLVGFKPKTVSDLEKGLEYIERELTK
VLSSVHVGQEMDPHDYESKALHAGMIDNLALEIADVAQIAAFDMPKGEAPLVEFGPFAADDSKPCILLVGHNVAPGTEVL
DYLEERGLDEEVEVLGICCTAWDVSRVDDRSKVIGPLSRQLHYVRMGIADVVVLDEQCIRADIVEEANEVGSRVIATRDL
VMAGLPDVTDEPTEKIIEKMVSGEWMGVFIEDLEKAAEVAVEVAIRVHERRKKEIPQPDPKKLQKEAKRCLGCGDCERVC
PNDLPIVEAMERAANGDFEGLADLFDRCVGCARCESECPTKLRVMNMIEDAWRLRTKEEKYKVRTGRGPIKDVEIRQVGG
PIVMGDIPGVVAFVACPNYPDDVKQVGKMVEELLERNYIVLTSGCTAMALGMYTDEDGKTLYEKYEDRFDAGCLVNTGSC
VSNAHILGACIKIAAIFAKKPLKGNFKEIADYILNRIGACGVLWGTMSQKALAISTGFTRWGIPIVYGPAGLKYQTLYIG
DLDGDWTVYDARTGKECKEYCPIHLKYAAEDWREALVQAVKLCIRPNDTPQGRQTKLQNYIELYKEFYNELPPDLPLYVR
DKNDVPITLRDEVMEYLEEVGWKPRKGITEPTLLEENVRG
>Mature_759_residues
SPFELEFEGLKVQIGSIEGFEPRGEGPLPCPTVSDLADWDRKLFARYRVIAFPICDMCCMCTYGRCNLAEGRRGACGIDI
RSNTARFTALKTCIGAACHAAHARHLVEYILEKLGDVEIDLGSEVDVMTPIFETLVGFKPKTVSDLEKGLEYIERELTKV
LSSVHVGQEMDPHDYESKALHAGMIDNLALEIADVAQIAAFDMPKGEAPLVEFGPFAADDSKPCILLVGHNVAPGTEVLD
YLEERGLDEEVEVLGICCTAWDVSRVDDRSKVIGPLSRQLHYVRMGIADVVVLDEQCIRADIVEEANEVGSRVIATRDLV
MAGLPDVTDEPTEKIIEKMVSGEWMGVFIEDLEKAAEVAVEVAIRVHERRKKEIPQPDPKKLQKEAKRCLGCGDCERVCP
NDLPIVEAMERAANGDFEGLADLFDRCVGCARCESECPTKLRVMNMIEDAWRLRTKEEKYKVRTGRGPIKDVEIRQVGGP
IVMGDIPGVVAFVACPNYPDDVKQVGKMVEELLERNYIVLTSGCTAMALGMYTDEDGKTLYEKYEDRFDAGCLVNTGSCV
SNAHILGACIKIAAIFAKKPLKGNFKEIADYILNRIGACGVLWGTMSQKALAISTGFTRWGIPIVYGPAGLKYQTLYIGD
LDGDWTVYDARTGKECKEYCPIHLKYAAEDWREALVQAVKLCIRPNDTPQGRQTKLQNYIELYKEFYNELPPDLPLYVRD
KNDVPITLRDEVMEYLEEVGWKPRKGITEPTLLEENVRG

Specific function: Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2)

COG id: COG1152

COG function: function code C; CO dehydrogenase/acetyl-CoA synthase alpha subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDA1_METKA (Q8TXF7)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614001.1
- ProteinModelPortal:   Q8TXF7
- SMR:   Q8TXF7
- GeneID:   1476818
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0717
- NMPDR:   fig|190192.1.peg.714
- HOGENOM:   HBG539676
- OMA:   ICCTAID
- ProtClustDB:   PRK00941
- BioCyc:   MKAN190192:MK0717-MONOMER
- BRENDA:   1.2.99.2
- GO:   GO:0005737
- HAMAP:   MF_01137
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR004460
- InterPro:   IPR016101
- InterPro:   IPR012285
- InterPro:   IPR004137
- InterPro:   IPR011254
- InterPro:   IPR016099
- Gene3D:   G3DSA:1.20.1270.30
- Gene3D:   G3DSA:1.10.1060.10
- Gene3D:   G3DSA:3.40.50.2030
- TIGRFAMs:   TIGR00314

Pfam domain/function: PF03063 Prismane; SSF56821 Prismane_like

EC number: =1.2.99.2

Molecular weight: Translated: 84638; Mature: 84507

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00198 4FE4S_FER_1; PS51379 4FE4S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPFELEFEGLKVQIGSIEGFEPRGEGPLPCPTVSDLADWDRKLFARYRVIAFPICDMCC
CCCCCEEECCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MCTYGRCNLAEGRRGACGIDIRSNTARFTALKTCIGAACHAAHARHLVEYILEKLGDVEI
HCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
DLGSEVDVMTPIFETLVGFKPKTVSDLEKGLEYIERELTKVLSSVHVGQEMDPHDYESKA
ECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LHAGMIDNLALEIADVAQIAAFDMPKGEAPLVEFGPFAADDSKPCILLVGHNVAPGTEVL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCEEEEEECCCCCHHHHH
DYLEERGLDEEVEVLGICCTAWDVSRVDDRSKVIGPLSRQLHYVRMGIADVVVLDEQCIR
HHHHHCCCCCHHHHHEEEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEECHHHHH
ADIVEEANEVGSRVIATRDLVMAGLPDVTDEPTEKIIEKMVSGEWMGVFIEDLEKAAEVA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHH
VEVAIRVHERRKKEIPQPDPKKLQKEAKRCLGCGDCERVCPNDLPIVEAMERAANGDFEG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHCCCCHHH
LADLFDRCVGCARCESECPTKLRVMNMIEDAWRLRTKEEKYKVRTGRGPIKDVEIRQVGG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHEEECCCCCCCCCCCEECCC
PIVMGDIPGVVAFVACPNYPDDVKQVGKMVEELLERNYIVLTSGCTAMALGMYTDEDGKT
CEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEECCHHHHEECCEECCCCHH
LYEKYEDRFDAGCLVNTGSCVSNAHILGACIKIAAIFAKKPLKGNFKEIADYILNRIGAC
HHHHHHHHCCCCCEEECCCHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCH
GVLWGTMSQKALAISTGFTRWGIPIVYGPAGLKYQTLYIGDLDGDWTVYDARTGKECKEY
HHHHHHCCCCEEEEECCCHHCCCEEEECCCCCEEEEEEEECCCCCEEEEECCCCHHHHHH
CPIHLKYAAEDWREALVQAVKLCIRPNDTPQGRQTKLQNYIELYKEFYNELPPDLPLYVR
CCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
DKNDVPITLRDEVMEYLEEVGWKPRKGITEPTLLEENVRG
CCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCC
>Mature Secondary Structure 
SPFELEFEGLKVQIGSIEGFEPRGEGPLPCPTVSDLADWDRKLFARYRVIAFPICDMCC
CCCCEEECCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
MCTYGRCNLAEGRRGACGIDIRSNTARFTALKTCIGAACHAAHARHLVEYILEKLGDVEI
HCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEE
DLGSEVDVMTPIFETLVGFKPKTVSDLEKGLEYIERELTKVLSSVHVGQEMDPHDYESKA
ECCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LHAGMIDNLALEIADVAQIAAFDMPKGEAPLVEFGPFAADDSKPCILLVGHNVAPGTEVL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEECCCCCCCCCCCEEEEEECCCCCHHHHH
DYLEERGLDEEVEVLGICCTAWDVSRVDDRSKVIGPLSRQLHYVRMGIADVVVLDEQCIR
HHHHHCCCCCHHHHHEEEECCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHEEECHHHHH
ADIVEEANEVGSRVIATRDLVMAGLPDVTDEPTEKIIEKMVSGEWMGVFIEDLEKAAEVA
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHH
VEVAIRVHERRKKEIPQPDPKKLQKEAKRCLGCGDCERVCPNDLPIVEAMERAANGDFEG
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCHHHHHHHHHCCCCHHH
LADLFDRCVGCARCESECPTKLRVMNMIEDAWRLRTKEEKYKVRTGRGPIKDVEIRQVGG
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHEEECCCCCCCCCCCEECCC
PIVMGDIPGVVAFVACPNYPDDVKQVGKMVEELLERNYIVLTSGCTAMALGMYTDEDGKT
CEEEECCCCEEEEEECCCCCHHHHHHHHHHHHHHHCCEEEEECCHHHHEECCEECCCCHH
LYEKYEDRFDAGCLVNTGSCVSNAHILGACIKIAAIFAKKPLKGNFKEIADYILNRIGAC
HHHHHHHHCCCCCEEECCCHHHCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCH
GVLWGTMSQKALAISTGFTRWGIPIVYGPAGLKYQTLYIGDLDGDWTVYDARTGKECKEY
HHHHHHCCCCEEEEECCCHHCCCEEEECCCCCEEEEEEEECCCCCEEEEECCCCHHHHHH
CPIHLKYAAEDWREALVQAVKLCIRPNDTPQGRQTKLQNYIELYKEFYNELPPDLPLYVR
CCEEEEEHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEE
DKNDVPITLRDEVMEYLEEVGWKPRKGITEPTLLEENVRG
CCCCCCEEEHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11930014