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The map label for this gene is CdhB

Identifier: 20094155

GI number: 20094155

Start: 685235

End: 685714

Strand: Direct

Name: CdhB

Synonym: MK0718

Alternate gene names: 20094155

Gene position: 685235-685714 (Clockwise)

Preceding gene: 20094154

Following gene: 20094156

Centisome position: 40.43

GC content: 61.46

Gene sequence:

>480_bases
TTGCCGCTACCGAGGGACCCCACACTGATTTACACGGACAAGGCCGAGGTGGCCCGAGCGCCGGTGCTCAAGATGGTGTT
CCGTCGCGCTAACGATTCGCTGATGATCGTCGGCCCGAGGGCCGTGGAGGACGAGGAGTGGCGAGAACTCCTGATGAAGC
TGCGCGAGGAGTTCAGGATGAGCGCCGTCTGCACGGCCCCGTACAAGGGCAATGACCTGGGTCGCAAGATGGGCATCGTC
GAGGCGGCGACCCTGCTCCAGCGGGACGCCCCGGTGCTCGGAGTTCACCCGGATCTTGTCGTGTTCACGGGCTCCCGCAC
CGACGTAACCGACCGCGTGCTTCAAGGACTTCGTCATGCGCGGCCGGACCTGGTGAAAGTATCATTGAACCCCGAGTACT
GTCCCAGCGCAGATTACTCGCTACCTACAGTGAAGAGGGATCAGTTCCTCCAAGAGTTGAAGGCTTTAGTGGGAATCTAG

Upstream 100 bases:

>100_bases
GCGACGAGGTGATGGAGTACCTGGAGGAGGTCGGTTGGAAGCCCCGGAAGGGTATCACCGAGCCGACCTTACTGGAGGAG
AACGTGCGGGGTTAAGCCCG

Downstream 100 bases:

>100_bases
GGGTGAGAAGTTGGGCATAGAATGGGAGGGAGTCAAAGTCGAGATAGGAGAGCTCGTGGTGGAAGGAGACTCCGAAAGTG
AGATGGAGGGGCCGACCCGC

Product: CO dehydrogenase/acetyl-CoA synthase epsilon subunit

Products: CO2; AH2

Alternate protein names: ACDS complex subunit epsilon

Number of amino acids: Translated: 159; Mature: 158

Protein sequence:

>159_residues
MPLPRDPTLIYTDKAEVARAPVLKMVFRRANDSLMIVGPRAVEDEEWRELLMKLREEFRMSAVCTAPYKGNDLGRKMGIV
EAATLLQRDAPVLGVHPDLVVFTGSRTDVTDRVLQGLRHARPDLVKVSLNPEYCPSADYSLPTVKRDQFLQELKALVGI

Sequences:

>Translated_159_residues
MPLPRDPTLIYTDKAEVARAPVLKMVFRRANDSLMIVGPRAVEDEEWRELLMKLREEFRMSAVCTAPYKGNDLGRKMGIV
EAATLLQRDAPVLGVHPDLVVFTGSRTDVTDRVLQGLRHARPDLVKVSLNPEYCPSADYSLPTVKRDQFLQELKALVGI
>Mature_158_residues
PLPRDPTLIYTDKAEVARAPVLKMVFRRANDSLMIVGPRAVEDEEWRELLMKLREEFRMSAVCTAPYKGNDLGRKMGIVE
AATLLQRDAPVLGVHPDLVVFTGSRTDVTDRVLQGLRHARPDLVKVSLNPEYCPSADYSLPTVKRDQFLQELKALVGI

Specific function: Part of a complex that catalyzes the reversible cleavage of acetyl-CoA, allowing autotrophic growth from CO(2). Probably has a structural role in stabilizing the alpha-epsilon subcomponent of the ACDS complex by forming a structural link between the two a

COG id: COG1880

COG function: function code C; CO dehydrogenase/acetyl-CoA synthase epsilon subunit

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CdhB family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACDE_METKA (Q8TXF6)

Other databases:

- EMBL:   AE009439
- RefSeq:   NP_614002.1
- ProteinModelPortal:   Q8TXF6
- SMR:   Q8TXF6
- GeneID:   1476819
- GenomeReviews:   AE009439_GR
- KEGG:   mka:MK0718
- NMPDR:   fig|190192.1.peg.715
- BioCyc:   MKAN190192:MK0718-MONOMER
- HAMAP:   MF_01134
- InterPro:   IPR003704

Pfam domain/function: PF02552 CO_dh

EC number: 1.2.99.2

Molecular weight: Translated: 17887; Mature: 17756

Theoretical pI: Translated: 8.21; Mature: 8.21

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLPRDPTLIYTDKAEVARAPVLKMVFRRANDSLMIVGPRAVEDEEWRELLMKLREEFRM
CCCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHH
SAVCTAPYKGNDLGRKMGIVEAATLLQRDAPVLGVHPDLVVFTGSRTDVTDRVLQGLRHA
HHEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCCHHHHHHHHHHHC
RPDLVKVSLNPEYCPSADYSLPTVKRDQFLQELKALVGI
CCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
PLPRDPTLIYTDKAEVARAPVLKMVFRRANDSLMIVGPRAVEDEEWRELLMKLREEFRM
CCCCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHH
SAVCTAPYKGNDLGRKMGIVEAATLLQRDAPVLGVHPDLVVFTGSRTDVTDRVLQGLRHA
HHEEECCCCCCHHHHHHHHHHHHHHHHCCCCEEECCCCEEEEECCCCCHHHHHHHHHHHC
RPDLVKVSLNPEYCPSADYSLPTVKRDQFLQELKALVGI
CCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: CO; H2O; A

Specific reaction: CO + H2O + A = CO2 + AH2

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11930014