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The map label for this gene is SUA5 [H]

Identifier: 20094073

GI number: 20094073

Start: 596667

End: 597305

Strand: Direct

Name: SUA5 [H]

Synonym: MK0635

Alternate gene names: 20094073

Gene position: 596667-597305 (Clockwise)

Preceding gene: 20094071

Following gene: 20094074

Centisome position: 35.2

GC content: 65.57

Gene sequence:

>639_bases
TTGGTTACCGTGCTCGAGGAGGAGGATCCCCACGCGGTTAAACACGTCGTCCGCGCCCTCCGTGCGGGGAAACTCGTCGC
CATCCCGTGCGACACTGTCTACTCCCTGAGCTGTGACGCTACGAACTCCGAGGCCGTTCGCCGTCTCTACGCCGCGAAGG
AGCGTCCCAAGGATAAGCCCGTCAGCGTCGCCGTCCACTCGCCCGAGAAGGCCCTGGAACTCCTGGAGCCCGTACCTAGA
CTCGAGGCGGCCTTGGAGACGCTGACCCCGGGTCCGGTCACCATCGTCGCCCCCCGAAGACCCGGTGTGGTCGCGCCCGA
GGTCGCGGCCGGTAGGCGCACCCTGGGGGTCAGGATCCCGGATCATCCGTTCTTCCTGCGCGTAGTTCGGAGGTTCGGGA
AACCGATCGTCACCACGTCCGCTAACGTCTCCGGTCGGCCCGCCCCGACCGATCCCGACGAAGTCTTCGAGCAGCTCGGC
GACCGCCTGGACATCCTGGTCGAGGGTGAGTGCCGCTTCGGCGAACCGTCCACCGTGATCGAACTCACGCCCGAAGGTAA
CATCGACATACTCCGGGAGGGCGCCATGCCGAAGGAGGAAATACTGGAAACACTAAGGGGGACGACCTCAGGTGCCTGA

Upstream 100 bases:

>100_bases
AGTAGTCCTCGGGACACGCGCACGTCGTCCTCGGAAAGGTCTGCGGAGAACGCGACAGCCCGGAGCCCCACGCACAGCAC
CCCCCGGGGGAGGCGCCTCA

Downstream 100 bases:

>100_bases
GAAGGGCCTCAAACCCTTCCTCACCGGCTTCCGCGAGACCGTCCTCGATCTGACCGACGGTGAGGGCGTCCTCGTGTACT
CCGGATGCGCCGGCACGTGC

Product: translation factor (SUA5)

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MVTVLEEEDPHAVKHVVRALRAGKLVAIPCDTVYSLSCDATNSEAVRRLYAAKERPKDKPVSVAVHSPEKALELLEPVPR
LEAALETLTPGPVTIVAPRRPGVVAPEVAAGRRTLGVRIPDHPFFLRVVRRFGKPIVTTSANVSGRPAPTDPDEVFEQLG
DRLDILVEGECRFGEPSTVIELTPEGNIDILREGAMPKEEILETLRGTTSGA

Sequences:

>Translated_212_residues
MVTVLEEEDPHAVKHVVRALRAGKLVAIPCDTVYSLSCDATNSEAVRRLYAAKERPKDKPVSVAVHSPEKALELLEPVPR
LEAALETLTPGPVTIVAPRRPGVVAPEVAAGRRTLGVRIPDHPFFLRVVRRFGKPIVTTSANVSGRPAPTDPDEVFEQLG
DRLDILVEGECRFGEPSTVIELTPEGNIDILREGAMPKEEILETLRGTTSGA
>Mature_212_residues
MVTVLEEEDPHAVKHVVRALRAGKLVAIPCDTVYSLSCDATNSEAVRRLYAAKERPKDKPVSVAVHSPEKALELLEPVPR
LEAALETLTPGPVTIVAPRRPGVVAPEVAAGRRTLGVRIPDHPFFLRVVRRFGKPIVTTSANVSGRPAPTDPDEVFEQLG
DRLDILVEGECRFGEPSTVIELTPEGNIDILREGAMPKEEILETLRGTTSGA

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=194, Percent_Identity=34.5360824742268, Blast_Score=84, Evalue=1e-16,
Organism=Escherichia coli, GI2367210, Length=153, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=2e-16,
Organism=Escherichia coli, GI87081864, Length=186, Percent_Identity=24.7311827956989, Blast_Score=65, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17537239, Length=193, Percent_Identity=34.1968911917098, Blast_Score=94, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI193205175, Length=119, Percent_Identity=35.2941176470588, Blast_Score=64, Evalue=6e-11,
Organism=Saccharomyces cerevisiae, GI6321269, Length=221, Percent_Identity=30.7692307692308, Blast_Score=86, Evalue=6e-18,
Organism=Drosophila melanogaster, GI78707274, Length=197, Percent_Identity=33.502538071066, Blast_Score=94, Evalue=5e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 22976; Mature: 22976

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTVLEEEDPHAVKHVVRALRAGKLVAIPCDTVYSLSCDATNSEAVRRLYAAKERPKDKP
CEEEECCCCCHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCCCC
VSVAVHSPEKALELLEPVPRLEAALETLTPGPVTIVAPRRPGVVAPEVAAGRRTLGVRIP
EEEEEECHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHCCCEEEEEECC
DHPFFLRVVRRFGKPIVTTSANVSGRPAPTDPDEVFEQLGDRLDILVEGECRFGEPSTVI
CCHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCEE
ELTPEGNIDILREGAMPKEEILETLRGTTSGA
EECCCCCEEEEECCCCCHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVTVLEEEDPHAVKHVVRALRAGKLVAIPCDTVYSLSCDATNSEAVRRLYAAKERPKDKP
CEEEECCCCCHHHHHHHHHHHCCCEEEEECCCEEEEECCCCCHHHHHHHHHHHCCCCCCC
VSVAVHSPEKALELLEPVPRLEAALETLTPGPVTIVAPRRPGVVAPEVAAGRRTLGVRIP
EEEEEECHHHHHHHHCCCHHHHHHHHHCCCCCEEEEECCCCCCCCCCHHCCCEEEEEECC
DHPFFLRVVRRFGKPIVTTSANVSGRPAPTDPDEVFEQLGDRLDILVEGECRFGEPSTVI
CCHHHHHHHHHHCCCEEEECCCCCCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCEE
ELTPEGNIDILREGAMPKEEILETLRGTTSGA
EECCCCCEEEEECCCCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]