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The map label for this gene is 20094071

Identifier: 20094071

GI number: 20094071

Start: 594757

End: 595908

Strand: Direct

Name: 20094071

Synonym: MK0633

Alternate gene names: NA

Gene position: 594757-595908 (Clockwise)

Preceding gene: 20094069

Following gene: 20094073

Centisome position: 35.09

GC content: 64.84

Gene sequence:

>1152_bases
TTGGAGAAGCTCGTCCTGCTACCGGGTCCGGTGATGGTGCACGAGGACGTCCTCCTCAGATCGGCGAAACAGGTCATGAA
CCACCGTAGCGAGGAGTTCGAGGAGATACTCACGGAGTGCGTGGAGCTGTCCAAGTACCTGTTTCAGACGGACGGCAACG
TCGCCATCATCACCGGTTCGGGCACCGCGGCCATGGAGGCGGCGATCTACAGCCTCCTCGAGCCCGGTGAGGAGGTCGTC
GCGGTGGTCAACGGGAAGTTCGGCGAGCGGTTCGCGGACATCGCCGAGCGTCGGGGCGCCGAGGTGCGCCGGGTGGAGTT
CGAGTGGGGCAAGGTCGCGGACCCCGAGCGCGTGGAGGAAGCCCTCGCGGACTCGGACGCGGAGGTCGTCACGCTCGTCC
ACAACGAGACTTCGACGACCGTGCTCAACCCGGCCGAGGAGATCGCTAGGATCTGCCGTGAGTACGACGCGCTGTTCGTC
GTGGACGCGATATCGTCGTTGGGTGGCGTCGAGTTCAGGATGGATGACTGGGGCGTCGACGTCTGCGTCACCGGTTCGCA
GAAGGTCCTGGGCTGTCCGCCGGGTCTCGCACTCGTGGCCGTCAACGACAGGGCCTTGGAGGTCATGGAGGAGAAGGACG
CGGGTAGCTACTACCTGGACATTCCCAAGTACCTCGAATACCTCGAGAAGGATCCGAAGCAGACGCCGTACACGCCCGCC
GTGAACGCCTTCTACGCCCTGCACGAGGCACTGAAGAGGCTGAAGGAGGAAGGACTCGAGGCCCGCTGGGAGCGCTACCG
TCTCATGCAACGGATCGTCCGCGAGGGGATCCGGGCACTCGGGCTCGAGTTGTTCGTCGAGGACGACGAGATAGCCTCGC
CGACCGTGACCGGAGTCACCTACCCCGAGGGCGTGGACGACCGTGAGTTCAGGGGTGAGATCCTGCGGGACCGCTACGAC
GTGGTGGTCGCCGGCGGTCAGGACCACCTAGCGGGTGAGATCTTCCGGATCGGACACATGGGTGAGGTCCGGATCCGCGA
TATGATCACGGCGGTGACCTGCATCGGTCTCGGTATGCGCGAGCTCGGCGTCGACGTGGACGTCGGTGCCGCCGCCGAGG
CTATGGCCGACGTGCTGTCAGAGGTATCGTAA

Upstream 100 bases:

>100_bases
CTCCGACCACCCGGAAATAGGTTTCCGGTTAGGATTTAACAGGATCGGGCCCGCCGGGAAAGCCCACAGACCTGGGCGCG
GTGTGAACGGGGTGTAGATC

Downstream 100 bases:

>100_bases
CGGCCACCGCTCGGTGCCGGTGCCCTCCTCCAGCGCCCTCACACCGTCTATCACGTTCCCGTTCAACACGATCGCTACCG
AGAATATCACCGTCCCCGGG

Product: aspartate aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 383

Protein sequence:

>383_residues
MEKLVLLPGPVMVHEDVLLRSAKQVMNHRSEEFEEILTECVELSKYLFQTDGNVAIITGSGTAAMEAAIYSLLEPGEEVV
AVVNGKFGERFADIAERRGAEVRRVEFEWGKVADPERVEEALADSDAEVVTLVHNETSTTVLNPAEEIARICREYDALFV
VDAISSLGGVEFRMDDWGVDVCVTGSQKVLGCPPGLALVAVNDRALEVMEEKDAGSYYLDIPKYLEYLEKDPKQTPYTPA
VNAFYALHEALKRLKEEGLEARWERYRLMQRIVREGIRALGLELFVEDDEIASPTVTGVTYPEGVDDREFRGEILRDRYD
VVVAGGQDHLAGEIFRIGHMGEVRIRDMITAVTCIGLGMRELGVDVDVGAAAEAMADVLSEVS

Sequences:

>Translated_383_residues
MEKLVLLPGPVMVHEDVLLRSAKQVMNHRSEEFEEILTECVELSKYLFQTDGNVAIITGSGTAAMEAAIYSLLEPGEEVV
AVVNGKFGERFADIAERRGAEVRRVEFEWGKVADPERVEEALADSDAEVVTLVHNETSTTVLNPAEEIARICREYDALFV
VDAISSLGGVEFRMDDWGVDVCVTGSQKVLGCPPGLALVAVNDRALEVMEEKDAGSYYLDIPKYLEYLEKDPKQTPYTPA
VNAFYALHEALKRLKEEGLEARWERYRLMQRIVREGIRALGLELFVEDDEIASPTVTGVTYPEGVDDREFRGEILRDRYD
VVVAGGQDHLAGEIFRIGHMGEVRIRDMITAVTCIGLGMRELGVDVDVGAAAEAMADVLSEVS
>Mature_383_residues
MEKLVLLPGPVMVHEDVLLRSAKQVMNHRSEEFEEILTECVELSKYLFQTDGNVAIITGSGTAAMEAAIYSLLEPGEEVV
AVVNGKFGERFADIAERRGAEVRRVEFEWGKVADPERVEEALADSDAEVVTLVHNETSTTVLNPAEEIARICREYDALFV
VDAISSLGGVEFRMDDWGVDVCVTGSQKVLGCPPGLALVAVNDRALEVMEEKDAGSYYLDIPKYLEYLEKDPKQTPYTPA
VNAFYALHEALKRLKEEGLEARWERYRLMQRIVREGIRALGLELFVEDDEIASPTVTGVTYPEGVDDREFRGEILRDRYD
VVVAGGQDHLAGEIFRIGHMGEVRIRDMITAVTCIGLGMRELGVDVDVGAAAEAMADVLSEVS

Specific function: Unknown

COG id: COG0075

COG function: function code E; Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557289, Length=358, Percent_Identity=34.9162011173184, Blast_Score=218, Evalue=7e-57,
Organism=Caenorhabditis elegans, GI17536281, Length=339, Percent_Identity=33.3333333333333, Blast_Score=204, Evalue=7e-53,
Organism=Saccharomyces cerevisiae, GI6321079, Length=355, Percent_Identity=28.4507042253521, Blast_Score=132, Evalue=8e-32,
Organism=Drosophila melanogaster, GI17530823, Length=376, Percent_Identity=34.0425531914894, Blast_Score=199, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: 2.6.1.-

Molecular weight: Translated: 42405; Mature: 42405

Theoretical pI: Translated: 4.23; Mature: 4.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEKLVLLPGPVMVHEDVLLRSAKQVMNHRSEEFEEILTECVELSKYLFQTDGNVAIITGS
CCCEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
GTAAMEAAIYSLLEPGEEVVAVVNGKFGERFADIAERRGAEVRRVEFEWGKVADPERVEE
CHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHH
ALADSDAEVVTLVHNETSTTVLNPAEEIARICREYDALFVVDAISSLGGVEFRMDDWGVD
HHCCCCCEEEEEEECCCCCEEECCHHHHHHHHHHHCHHHHHHHHHHCCCCEEEECCCCEE
VCVTGSQKVLGCPPGLALVAVNDRALEVMEEKDAGSYYLDIPKYLEYLEKDPKQTPYTPA
EEEECCCEEEECCCCEEEEEECCHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCCCHH
VNAFYALHEALKRLKEEGLEARWERYRLMQRIVREGIRALGLELFVEDDEIASPTVTGVT
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCCCCEEECCC
YPEGVDDREFRGEILRDRYDVVVAGGQDHLAGEIFRIGHMGEVRIRDMITAVTCIGLGMR
CCCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHEECCCCCHHHHHHHHHHHHHHCCHH
ELGVDVDVGAAAEAMADVLSEVS
HHCCCCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MEKLVLLPGPVMVHEDVLLRSAKQVMNHRSEEFEEILTECVELSKYLFQTDGNVAIITGS
CCCEEECCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEECC
GTAAMEAAIYSLLEPGEEVVAVVNGKFGERFADIAERRGAEVRRVEFEWGKVADPERVEE
CHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHH
ALADSDAEVVTLVHNETSTTVLNPAEEIARICREYDALFVVDAISSLGGVEFRMDDWGVD
HHCCCCCEEEEEEECCCCCEEECCHHHHHHHHHHHCHHHHHHHHHHCCCCEEEECCCCEE
VCVTGSQKVLGCPPGLALVAVNDRALEVMEEKDAGSYYLDIPKYLEYLEKDPKQTPYTPA
EEEECCCEEEECCCCEEEEEECCHHHHHHHHCCCCCEEEEHHHHHHHHHCCCCCCCCCHH
VNAFYALHEALKRLKEEGLEARWERYRLMQRIVREGIRALGLELFVEDDEIASPTVTGVT
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHCHHEEECCCCCCCCEEECCC
YPEGVDDREFRGEILRDRYDVVVAGGQDHLAGEIFRIGHMGEVRIRDMITAVTCIGLGMR
CCCCCCCHHHHHHHHHCCCCEEEECCCCHHHHHHHEECCCCCHHHHHHHHHHHHHHCCHH
ELGVDVDVGAAAEAMADVLSEVS
HHCCCCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]