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The map label for this gene is hflX [C]

Identifier: 20093894

GI number: 20093894

Start: 424099

End: 425370

Strand: Direct

Name: hflX [C]

Synonym: MK0456

Alternate gene names: 20093894

Gene position: 424099-425370 (Clockwise)

Preceding gene: 20093893

Following gene: 20093916

Centisome position: 25.02

GC content: 56.37

Gene sequence:

>1272_bases
TTGCCCAGTCGCCCTCGGGCGGTTTTGGTTGAACGGTTGGAGTGGAGACAGGAGAGCCGCATTGATGAGCTGAAAGAGCT
GGCCGAATCTGCCGGCTACGACGTCGTCGGCTCGTTCAGACAGGTCCGTCACGAAGACCCTCGATACCATATAGGGGAAG
GAAAGGTCAAAGAGCTGGCGGAGTTCGTGCGCGAGAACGACGTGGACAAAGTCATCTTCGAGAACGAGATCAAGCCAGTC
CAGGCGTTCAACCTTGCAGGTGAGCTGGGAGTTGAGGTAATCGACAGATTCCAGTTGATCCTCGAGATATTCGCACAGAG
AGCTCGAACCCGCGAAGCCAAACTGCAGGTGAAGCTCGCGCAGCTCAAGTACGAACTGCCCAGGGCACGTGAGATGGTGA
ACCTAGCTAAAAAGGAGGAGCGTCCGGGTTTCCGCGGCCTCGGTAAGTACGAAGCCGACAAATACGAGGAAATGATCCGA
CGGAAGATCGCCAAGATAGAGCGTGAACTCCGACGGATCGAGAAAGATCGAGAGCTAAAGAGGAAGCACCGACATCGGTT
AGGGTTCGAACTAGTTACGTTGGCCGGGTACACATGTGCGGGTAAAAGCACCCTAATGCGGGCCCTAACCGACGAGACGG
TCTACGTGGACTCCAAGATGTTCTCCACGCTGGATACCAAAACTAGAGCCGTAGACCTGGACGGACACCGCGTACTCCTC
ACCGACACCGTCGGATTCGTGGATAACCTACCCCACTGGCTCGTGGAGTCTTTCAAATCGACTCTTGAGGAAACCGCCCA
AGCCGACCTGGTCCTGCTGGTGGTAGACGTCAGTGACGAGTTACCGGAGATCAAGCGTAAACTCCGGGTGTGCCACAGGA
CGTTGGAGGAGATAGGCGCTGAAGGCCCCATCGTGACCGCGCTCAACAAGGCGGATCTGATAGGATGGGAGGAAGCGGAG
CGACGCCTCCGGGAACTAGAAGGGTACGTGTCTCATCCGGTGGTCGTTTCCGCTAAGACAGGGGAAGGCCTCGACGACCT
CAAGGCCGAGATGCGTACGGTGCTCTCCAGGTACTGGAAGAACGTCCGCATCGAGCTACCGATGAGGAACGAAACCATGC
GGGTTGTTTCGAAACTACATGAACTCGGAAACGTGCTGGACGAGCGTTGGTCGAACGACGGTGTTGAGGTGTTCCTCGAG
GTCAGTGAGAAGGCCCTGGGAACCGTGAGAGGAACCGTGAAGGGGTTCGGTAAAGTGGAGGTATTGGATTAA

Upstream 100 bases:

>100_bases
CCGTTCAAGTACGCCGAGACCGTGGCCGAGCGAGAGGTAGTGGAAATGGCGCATAAGCTCGCCTACGGAGTCTACAGAGG
CGTGAAGATGGGGTTGAAGG

Downstream 100 bases:

>100_bases
TCCTCACGCGAACTCTTCCGGTACCATTCCGGAACTTGGATCAGTGAATAACCCCCGTCGGGACCGGGCTTTCCGTCGAT
CTTGAAACCCATCTTACGGA

Product: HflX family GTPase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MPSRPRAVLVERLEWRQESRIDELKELAESAGYDVVGSFRQVRHEDPRYHIGEGKVKELAEFVRENDVDKVIFENEIKPV
QAFNLAGELGVEVIDRFQLILEIFAQRARTREAKLQVKLAQLKYELPRAREMVNLAKKEERPGFRGLGKYEADKYEEMIR
RKIAKIERELRRIEKDRELKRKHRHRLGFELVTLAGYTCAGKSTLMRALTDETVYVDSKMFSTLDTKTRAVDLDGHRVLL
TDTVGFVDNLPHWLVESFKSTLEETAQADLVLLVVDVSDELPEIKRKLRVCHRTLEEIGAEGPIVTALNKADLIGWEEAE
RRLRELEGYVSHPVVVSAKTGEGLDDLKAEMRTVLSRYWKNVRIELPMRNETMRVVSKLHELGNVLDERWSNDGVEVFLE
VSEKALGTVRGTVKGFGKVEVLD

Sequences:

>Translated_423_residues
MPSRPRAVLVERLEWRQESRIDELKELAESAGYDVVGSFRQVRHEDPRYHIGEGKVKELAEFVRENDVDKVIFENEIKPV
QAFNLAGELGVEVIDRFQLILEIFAQRARTREAKLQVKLAQLKYELPRAREMVNLAKKEERPGFRGLGKYEADKYEEMIR
RKIAKIERELRRIEKDRELKRKHRHRLGFELVTLAGYTCAGKSTLMRALTDETVYVDSKMFSTLDTKTRAVDLDGHRVLL
TDTVGFVDNLPHWLVESFKSTLEETAQADLVLLVVDVSDELPEIKRKLRVCHRTLEEIGAEGPIVTALNKADLIGWEEAE
RRLRELEGYVSHPVVVSAKTGEGLDDLKAEMRTVLSRYWKNVRIELPMRNETMRVVSKLHELGNVLDERWSNDGVEVFLE
VSEKALGTVRGTVKGFGKVEVLD
>Mature_422_residues
PSRPRAVLVERLEWRQESRIDELKELAESAGYDVVGSFRQVRHEDPRYHIGEGKVKELAEFVRENDVDKVIFENEIKPVQ
AFNLAGELGVEVIDRFQLILEIFAQRARTREAKLQVKLAQLKYELPRAREMVNLAKKEERPGFRGLGKYEADKYEEMIRR
KIAKIERELRRIEKDRELKRKHRHRLGFELVTLAGYTCAGKSTLMRALTDETVYVDSKMFSTLDTKTRAVDLDGHRVLLT
DTVGFVDNLPHWLVESFKSTLEETAQADLVLLVVDVSDELPEIKRKLRVCHRTLEEIGAEGPIVTALNKADLIGWEEAER
RLRELEGYVSHPVVVSAKTGEGLDDLKAEMRTVLSRYWKNVRIELPMRNETMRVVSKLHELGNVLDERWSNDGVEVFLEV
SEKALGTVRGTVKGFGKVEVLD

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=213, Percent_Identity=37.0892018779343, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI310124267, Length=213, Percent_Identity=37.0892018779343, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI310124171, Length=213, Percent_Identity=37.0892018779343, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI310124169, Length=213, Percent_Identity=37.0892018779343, Blast_Score=116, Evalue=4e-26,
Organism=Homo sapiens, GI310133118, Length=215, Percent_Identity=36.2790697674419, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI310133116, Length=213, Percent_Identity=36.6197183098592, Blast_Score=113, Evalue=4e-25,
Organism=Escherichia coli, GI1790615, Length=405, Percent_Identity=36.7901234567901, Blast_Score=209, Evalue=2e-55,
Organism=Caenorhabditis elegans, GI17561038, Length=288, Percent_Identity=28.125, Blast_Score=99, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24650079, Length=332, Percent_Identity=29.2168674698795, Blast_Score=107, Evalue=2e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 48730; Mature: 48598

Theoretical pI: Translated: 6.63; Mature: 6.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSRPRAVLVERLEWRQESRIDELKELAESAGYDVVGSFRQVRHEDPRYHIGEGKVKELA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEECCCCHHHHHH
EFVRENDVDKVIFENEIKPVQAFNLAGELGVEVIDRFQLILEIFAQRARTREAKLQVKLA
HHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLKYELPRAREMVNLAKKEERPGFRGLGKYEADKYEEMIRRKIAKIERELRRIEKDRELK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKHRHRLGFELVTLAGYTCAGKSTLMRALTDETVYVDSKMFSTLDTKTRAVDLDGHRVLL
HHHHHHCCHHHHHHHCCCCCCHHHHHHHHCCCCEEECHHHHHHHCCCCEEEECCCCEEEE
TDTVGFVDNLPHWLVESFKSTLEETAQADLVLLVVDVSDELPEIKRKLRVCHRTLEEIGA
EECHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCC
EGPIVTALNKADLIGWEEAERRLRELEGYVSHPVVVSAKTGEGLDDLKAEMRTVLSRYWK
CCCEEEEECHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHC
NVRIELPMRNETMRVVSKLHELGNVLDERWSNDGVEVFLEVSEKALGTVRGTVKGFGKVE
CCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
VLD
ECC
>Mature Secondary Structure 
PSRPRAVLVERLEWRQESRIDELKELAESAGYDVVGSFRQVRHEDPRYHIGEGKVKELA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEECCCCHHHHHH
EFVRENDVDKVIFENEIKPVQAFNLAGELGVEVIDRFQLILEIFAQRARTREAKLQVKLA
HHHHHCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLKYELPRAREMVNLAKKEERPGFRGLGKYEADKYEEMIRRKIAKIERELRRIEKDRELK
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RKHRHRLGFELVTLAGYTCAGKSTLMRALTDETVYVDSKMFSTLDTKTRAVDLDGHRVLL
HHHHHHCCHHHHHHHCCCCCCHHHHHHHHCCCCEEECHHHHHHHCCCCEEEECCCCEEEE
TDTVGFVDNLPHWLVESFKSTLEETAQADLVLLVVDVSDELPEIKRKLRVCHRTLEEIGA
EECHHHHHCCHHHHHHHHHHHHHHHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHCC
EGPIVTALNKADLIGWEEAERRLRELEGYVSHPVVVSAKTGEGLDDLKAEMRTVLSRYWK
CCCEEEEECHHHCCCHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHC
NVRIELPMRNETMRVVSKLHELGNVLDERWSNDGVEVFLEVSEKALGTVRGTVKGFGKVE
CCEEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCEE
VLD
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]