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The map label for this gene is secY [H]

Identifier: 18311367

GI number: 18311367

Start: 2742012

End: 2743289

Strand: Reverse

Name: secY [H]

Synonym: CPE2385

Alternate gene names: 18311367

Gene position: 2743289-2742012 (Counterclockwise)

Preceding gene: 18311368

Following gene: 18311366

Centisome position: 90.49

GC content: 31.53

Gene sequence:

>1278_bases
GTGCTATCAACCCTACGTAATGCCTGGAAGGTTCAAGATTTAAGAAAAAAAATAATTTGGACTGTATTCTTAATAGCAAT
TTTCAGGATGGGAAGTTATATTCCTGTTCCTGGAATTGATACAGATAGTCTAAAAGCTTTAACACAATCAGGAAGCTTAG
TAAGCTTCTATGATTTAATTTCTGGTGGTTCTTTTAGTAGATTTAGTATATTCGCTTTAGGTGTTGTACCATACATCAAT
GCTTCAATCATTATGCAACTTTTAACAGTTGCAATTCCTAAATTAGAACAATTATCTAAAGAGGGAGATGATGGAAGAAA
GAAAATCCAAAAGATAACTAGATATGCTTCAATTGTTATTGGAGCAATCACTGCTTATGGAAGTTATGTGATAATTAACA
ATGTTGGCGCACTTAAGAGCAATTCTCCAGTTAGTATGTTTTTAATATTACTAACACTAGTAGTTGGATCAACTTTCTTA
ATGTGGTTAGGAGATCAAATTACAGTTAAAGGAGTAGGAAATGGTACTTCTTTGATAATATTTGCAAATATATTATCAAG
CTTACCAATGACTGGTTATCAAATATATAACTTAAGTAAGATAGGTAAAATAAATGTTGTTGAAGTAGCATTATTTATTT
TCTTTACATTAGCTTTATTAGCAGGTGTAATTTACTTATCATTAGCTGAAAGAAGAATTACTGTACAATATGCAGGTAAA
GCCGTAGGTAATAAAATGATGAAGGGACAATCAACTCATATTCCATTAAGTATTATTGGAACAACTGTTATAGCAATAAT
CTTTGCTATGTCTGTTATGAGTTTCCCAACAACTATAGCTCAATTCTTCCCAGAAGCTGGATGGTCACAATGGATTACAG
GATCTTCTTACAGTCCTTTCAATGCAAAGACTTGGATGTATCCAGTATTATATGCATTACTGACTATATTCTTTACTTGG
TTCTATACTCAAATAACATTTAAGCCAGATGAAATGGCTGAGAATATGCATAAATCATCAGGTTTCATTCCTGGAATAAG
ACCTGGAAAACCAACAGAGATTTATTTAGAGAAAGTATTAAATAGAATTTCAATGTTTGGTGGATGTTTTGCTGCTATTA
TAGCAGTAGTTCCTATTTTAGTTGCAAACTATACTCCTTTCCAAGGAATACAGTTTGGAGGAACATCACTGTTAATTCTA
GTTTCTGTTTCATTAGAAATAATGAGACAATTAGAATCTCAATTAACAATGAGACATTACCAAGGATTCTTAAAATAG

Upstream 100 bases:

>100_bases
GAAACATAGAAAAGAGCTTAACTATCGCAGGTTGCAAGTTATCAAAGCAAGCAGCTGAAAAAATAGTTGCAGCTGGAGGA
AAAGTTGAGGTGAAATAATC

Downstream 100 bases:

>100_bases
AAATACAAGTTATGGAGATGATGCCCGTGAAGATAGTTTTATTAGGTCCTCCTGGAGCAGGAAAAGGAACACAGGCAAAA
TCAATTAGTAATAGATATTC

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MLSTLRNAWKVQDLRKKIIWTVFLIAIFRMGSYIPVPGIDTDSLKALTQSGSLVSFYDLISGGSFSRFSIFALGVVPYIN
ASIIMQLLTVAIPKLEQLSKEGDDGRKKIQKITRYASIVIGAITAYGSYVIINNVGALKSNSPVSMFLILLTLVVGSTFL
MWLGDQITVKGVGNGTSLIIFANILSSLPMTGYQIYNLSKIGKINVVEVALFIFFTLALLAGVIYLSLAERRITVQYAGK
AVGNKMMKGQSTHIPLSIIGTTVIAIIFAMSVMSFPTTIAQFFPEAGWSQWITGSSYSPFNAKTWMYPVLYALLTIFFTW
FYTQITFKPDEMAENMHKSSGFIPGIRPGKPTEIYLEKVLNRISMFGGCFAAIIAVVPILVANYTPFQGIQFGGTSLLIL
VSVSLEIMRQLESQLTMRHYQGFLK

Sequences:

>Translated_425_residues
MLSTLRNAWKVQDLRKKIIWTVFLIAIFRMGSYIPVPGIDTDSLKALTQSGSLVSFYDLISGGSFSRFSIFALGVVPYIN
ASIIMQLLTVAIPKLEQLSKEGDDGRKKIQKITRYASIVIGAITAYGSYVIINNVGALKSNSPVSMFLILLTLVVGSTFL
MWLGDQITVKGVGNGTSLIIFANILSSLPMTGYQIYNLSKIGKINVVEVALFIFFTLALLAGVIYLSLAERRITVQYAGK
AVGNKMMKGQSTHIPLSIIGTTVIAIIFAMSVMSFPTTIAQFFPEAGWSQWITGSSYSPFNAKTWMYPVLYALLTIFFTW
FYTQITFKPDEMAENMHKSSGFIPGIRPGKPTEIYLEKVLNRISMFGGCFAAIIAVVPILVANYTPFQGIQFGGTSLLIL
VSVSLEIMRQLESQLTMRHYQGFLK
>Mature_425_residues
MLSTLRNAWKVQDLRKKIIWTVFLIAIFRMGSYIPVPGIDTDSLKALTQSGSLVSFYDLISGGSFSRFSIFALGVVPYIN
ASIIMQLLTVAIPKLEQLSKEGDDGRKKIQKITRYASIVIGAITAYGSYVIINNVGALKSNSPVSMFLILLTLVVGSTFL
MWLGDQITVKGVGNGTSLIIFANILSSLPMTGYQIYNLSKIGKINVVEVALFIFFTLALLAGVIYLSLAERRITVQYAGK
AVGNKMMKGQSTHIPLSIIGTTVIAIIFAMSVMSFPTTIAQFFPEAGWSQWITGSSYSPFNAKTWMYPVLYALLTIFFTW
FYTQITFKPDEMAENMHKSSGFIPGIRPGKPTEIYLEKVLNRISMFGGCFAAIIAVVPILVANYTPFQGIQFGGTSLLIL
VSVSLEIMRQLESQLTMRHYQGFLK

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel [H]

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family [H]

Homologues:

Organism=Escherichia coli, GI1789696, Length=422, Percent_Identity=38.6255924170616, Blast_Score=265, Evalue=4e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002208
- InterPro:   IPR023201 [H]

Pfam domain/function: PF00344 SecY [H]

EC number: NA

Molecular weight: Translated: 46927; Mature: 46927

Theoretical pI: Translated: 10.15; Mature: 10.15

Prosite motif: PS00755 SECY_1 ; PS00756 SECY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSTLRNAWKVQDLRKKIIWTVFLIAIFRMGSYIPVPGIDTDSLKALTQSGSLVSFYDLI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEHHHHHH
SGGSFSRFSIFALGVVPYINASIIMQLLTVAIPKLEQLSKEGDDGRKKIQKITRYASIVI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GAITAYGSYVIINNVGALKSNSPVSMFLILLTLVVGSTFLMWLGDQITVKGVGNGTSLII
HHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHH
FANILSSLPMTGYQIYNLSKIGKINVVEVALFIFFTLALLAGVIYLSLAERRITVQYAGK
HHHHHHHCCCCCEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHH
AVGNKMMKGQSTHIPLSIIGTTVIAIIFAMSVMSFPTTIAQFFPEAGWSQWITGSSYSPF
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCC
NAKTWMYPVLYALLTIFFTWFYTQITFKPDEMAENMHKSSGFIPGIRPGKPTEIYLEKVL
CCHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
NRISMFGGCFAAIIAVVPILVANYTPFQGIQFGGTSLLILVSVSLEIMRQLESQLTMRHY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHH
QGFLK
HHHCC
>Mature Secondary Structure
MLSTLRNAWKVQDLRKKIIWTVFLIAIFRMGSYIPVPGIDTDSLKALTQSGSLVSFYDLI
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCEEHHHHHH
SGGSFSRFSIFALGVVPYINASIIMQLLTVAIPKLEQLSKEGDDGRKKIQKITRYASIVI
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHH
GAITAYGSYVIINNVGALKSNSPVSMFLILLTLVVGSTFLMWLGDQITVKGVGNGTSLII
HHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHH
FANILSSLPMTGYQIYNLSKIGKINVVEVALFIFFTLALLAGVIYLSLAERRITVQYAGK
HHHHHHHCCCCCEEEEEHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEHHH
AVGNKMMKGQSTHIPLSIIGTTVIAIIFAMSVMSFPTTIAQFFPEAGWSQWITGSSYSPF
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCCC
NAKTWMYPVLYALLTIFFTWFYTQITFKPDEMAENMHKSSGFIPGIRPGKPTEIYLEKVL
CCHHHHHHHHHHHHHHHHHHHHHHEEECHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
NRISMFGGCFAAIIAVVPILVANYTPFQGIQFGGTSLLILVSVSLEIMRQLESQLTMRHY
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEHHHHHHHHHHHHHHHHHHHHHH
QGFLK
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2110998; 2139212; 2113521; 8635744; 9384377 [H]