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The map label for this gene is yicI [C]

Identifier: 18311321

GI number: 18311321

Start: 2693978

End: 2696125

Strand: Reverse

Name: yicI [C]

Synonym: CPE2339

Alternate gene names: 18311321

Gene position: 2696125-2693978 (Counterclockwise)

Preceding gene: 18311322

Following gene: 18311320

Centisome position: 88.94

GC content: 28.91

Gene sequence:

>2148_bases
ATGAGAATTAATTGTATTAATAATCACATAACTAAATATACTTTTGGAATTCCTTTTAATACTGAGTCAGTTGTTTTAAA
AGAAGGTTCAGAAATGGAGAACCAAGAATTAAAGTATTTAAATTTTGAGAATAACACTTTTACATTAAAACTTAAAGAGG
AAGATATAGTTTATGGACTAGGTGAAAATGTAAGAGGATTAAATAAAAGAGGATGGAGATATGAAAGTTTTTGTACAGAT
GATTTTTCACATACTCCAGAGAAAAAAAGCCTTTATGGAGCTCATAACTTCTTAATGATATATGGAGAAAAAACTTTTGG
GATATTTATAGATTATCCTGGAAGAGTAAAGTTTGATGTTGGATATAGGAGAAGAGATGAATTAAAGATAGAAATTGATG
ATGAAAATTTTGCTTTATATATTATTGAAGGAGATACTTTAAAGGAAATAGCAAAAAGCTTTAGAGGGCTTATAGGTGAA
AGTTACATGGCTCCTAAATGGGCCTTTGGTGCTCAACAAAGTAGATGGAGTTATAAGGATAGTAAAGAGGTTCTTGAAGT
CCTAGATAATTTTAATGAATCAGAACTTCCTCTTGATTGTATATATCTTGATATAGATTATATGGAGGATTTCAAGAACT
TTACCATAAATAAAGAAGCCTTCCCTGATTTTGAAAACTTTGTGAAGGAAGTTAAAGAAAAAGGAGTCAGACTTATTCCA
ATAATCGATGCTGGATGCAAAATTGAAGAGGGATATGATGTTTATGAGGAAGGTGTTAAAAATGGTTATTACTGTTTAGA
TGAGGAAGGAAAACCTTTTGTAGCAGCAGTTTGGCCAGGGAGAGTTCATTTTCCAGACTTTTTAAATAAGGATGCAAGAT
TATGGTTTGGAAATAAATATAAAGTACTTACTGATAAAGGAATAGAAGGCTTTTGGAATGATATGAATGAGCCTGCAATA
TTCTATTCTGAAAAAAGATTAAATGAAGCTTTTGAAAAAATATCAGAAGCAAAAGGAAGGAATTTAGGTATATATGATTA
TTTTGATGTTAAGGATACATTCCCAAGACTTCAAAATAGTATGGAAGATTATCAAAGCTTCTATCATAGAGTAGGAAATG
GAAAAATAAGACATGACAAGATTCATAATCTTTTTGGATTTAATATGACAAGAGCAGCATCTGAAGGTCTTGAAAATATA
GATGAAAATAAGAGGTTTTTACTATTTTCTAGAGCATCAACAGTTGGTATGCATAGATATGGAGGAATATGGACTGGAGA
TAACATGTCTTGGTGGGAACACATTAAGTTAAACCTTCAAATGATGCCAAATATTAATATGTGTGGATTTATCTATACAG
GAGCTGATACTGGCGGATTTGGAGGAGATACAACAGAAGATTTAGTTATAAGATGGTCACAATTTAGTATGTTTACACCT
TTATTCAGAAATCACTCAGCTTTAGGTACAAGACATCAAGAACCATATTCATTTAGAGGTGAAAGTGTCAAAGTATTAAA
AAATATATTGGAGTTAAGATATGTTATGGTTCCATATCTTTATAGTGAGTATATGAAAGCTATTTTAAATAATGAAATGT
ATTTTAAACCATTAACATTTGAATATAGTGATAACTTTGTAAAAAGAGTAGAAGATCAAATGCTTTTAGGTGATAGTTTA
ATGGTAGCACCTATATATGAGCAAAATGCTTTAGGAAGATATGTATATATTCCAGAGGAAATGCTTTTATGGAGAGCTAG
AAAATATGATGATGGAGATTATGAGGTTTTAGAAAAAGGACATCATTATGTTGAAGCAAAATTAAATGAAGTTCCTATAT
TTATAAGAAAAAATAAAATAGTAACAATGGCAAGTAAGCCAAGAAAAAGGGTAGAAGAAATAGATACTAGTGAATTAAAT
CTAATTGCTTTTGTTTGTGATAAAGCTGAATACATTTATTACAATGATGATGGTATCACTAAAAATTATAAGAATGGTGA
GTATGAAGAGCTAAAAATTAAGATTACAAAAGTACAATCAGATTATGAGGTATTAGTAGAAAATAAAAATTCAAGAGTTA
AAAATTTAAATATAAAAATATTTGATTTAAATAAAAATATGATTGAAAAAGAGATATTGATTCAATAA

Upstream 100 bases:

>100_bases
CTAAAAAGGAAGAGCATAAGCATATAATTTTTGAAACAAAGATAATAGAAAGAGAGTCATGTAAGAAAGTGGTATAGTAC
TTATAATTGGGGGAGATATT

Downstream 100 bases:

>100_bases
TAGTAACTAGGGGGAAGTAATATGAGAAGAGCAAGTGGAATAATAATGCATATTGCTTCCTTACCTGGAAAGTATGGAAT
AGGTACTTTTGGTAAGGAAG

Product: alpha-glucosidase

Products: NA

Alternate protein names: Alpha-glucosidase II [H]

Number of amino acids: Translated: 715; Mature: 715

Protein sequence:

>715_residues
MRINCINNHITKYTFGIPFNTESVVLKEGSEMENQELKYLNFENNTFTLKLKEEDIVYGLGENVRGLNKRGWRYESFCTD
DFSHTPEKKSLYGAHNFLMIYGEKTFGIFIDYPGRVKFDVGYRRRDELKIEIDDENFALYIIEGDTLKEIAKSFRGLIGE
SYMAPKWAFGAQQSRWSYKDSKEVLEVLDNFNESELPLDCIYLDIDYMEDFKNFTINKEAFPDFENFVKEVKEKGVRLIP
IIDAGCKIEEGYDVYEEGVKNGYYCLDEEGKPFVAAVWPGRVHFPDFLNKDARLWFGNKYKVLTDKGIEGFWNDMNEPAI
FYSEKRLNEAFEKISEAKGRNLGIYDYFDVKDTFPRLQNSMEDYQSFYHRVGNGKIRHDKIHNLFGFNMTRAASEGLENI
DENKRFLLFSRASTVGMHRYGGIWTGDNMSWWEHIKLNLQMMPNINMCGFIYTGADTGGFGGDTTEDLVIRWSQFSMFTP
LFRNHSALGTRHQEPYSFRGESVKVLKNILELRYVMVPYLYSEYMKAILNNEMYFKPLTFEYSDNFVKRVEDQMLLGDSL
MVAPIYEQNALGRYVYIPEEMLLWRARKYDDGDYEVLEKGHHYVEAKLNEVPIFIRKNKIVTMASKPRKRVEEIDTSELN
LIAFVCDKAEYIYYNDDGITKNYKNGEYEELKIKITKVQSDYEVLVENKNSRVKNLNIKIFDLNKNMIEKEILIQ

Sequences:

>Translated_715_residues
MRINCINNHITKYTFGIPFNTESVVLKEGSEMENQELKYLNFENNTFTLKLKEEDIVYGLGENVRGLNKRGWRYESFCTD
DFSHTPEKKSLYGAHNFLMIYGEKTFGIFIDYPGRVKFDVGYRRRDELKIEIDDENFALYIIEGDTLKEIAKSFRGLIGE
SYMAPKWAFGAQQSRWSYKDSKEVLEVLDNFNESELPLDCIYLDIDYMEDFKNFTINKEAFPDFENFVKEVKEKGVRLIP
IIDAGCKIEEGYDVYEEGVKNGYYCLDEEGKPFVAAVWPGRVHFPDFLNKDARLWFGNKYKVLTDKGIEGFWNDMNEPAI
FYSEKRLNEAFEKISEAKGRNLGIYDYFDVKDTFPRLQNSMEDYQSFYHRVGNGKIRHDKIHNLFGFNMTRAASEGLENI
DENKRFLLFSRASTVGMHRYGGIWTGDNMSWWEHIKLNLQMMPNINMCGFIYTGADTGGFGGDTTEDLVIRWSQFSMFTP
LFRNHSALGTRHQEPYSFRGESVKVLKNILELRYVMVPYLYSEYMKAILNNEMYFKPLTFEYSDNFVKRVEDQMLLGDSL
MVAPIYEQNALGRYVYIPEEMLLWRARKYDDGDYEVLEKGHHYVEAKLNEVPIFIRKNKIVTMASKPRKRVEEIDTSELN
LIAFVCDKAEYIYYNDDGITKNYKNGEYEELKIKITKVQSDYEVLVENKNSRVKNLNIKIFDLNKNMIEKEILIQ
>Mature_715_residues
MRINCINNHITKYTFGIPFNTESVVLKEGSEMENQELKYLNFENNTFTLKLKEEDIVYGLGENVRGLNKRGWRYESFCTD
DFSHTPEKKSLYGAHNFLMIYGEKTFGIFIDYPGRVKFDVGYRRRDELKIEIDDENFALYIIEGDTLKEIAKSFRGLIGE
SYMAPKWAFGAQQSRWSYKDSKEVLEVLDNFNESELPLDCIYLDIDYMEDFKNFTINKEAFPDFENFVKEVKEKGVRLIP
IIDAGCKIEEGYDVYEEGVKNGYYCLDEEGKPFVAAVWPGRVHFPDFLNKDARLWFGNKYKVLTDKGIEGFWNDMNEPAI
FYSEKRLNEAFEKISEAKGRNLGIYDYFDVKDTFPRLQNSMEDYQSFYHRVGNGKIRHDKIHNLFGFNMTRAASEGLENI
DENKRFLLFSRASTVGMHRYGGIWTGDNMSWWEHIKLNLQMMPNINMCGFIYTGADTGGFGGDTTEDLVIRWSQFSMFTP
LFRNHSALGTRHQEPYSFRGESVKVLKNILELRYVMVPYLYSEYMKAILNNEMYFKPLTFEYSDNFVKRVEDQMLLGDSL
MVAPIYEQNALGRYVYIPEEMLLWRARKYDDGDYEVLEKGHHYVEAKLNEVPIFIRKNKIVTMASKPRKRVEEIDTSELN
LIAFVCDKAEYIYYNDDGITKNYKNGEYEELKIKITKVQSDYEVLVENKNSRVKNLNIKIFDLNKNMIEKEILIQ

Specific function: Unknown

COG id: COG1501

COG function: function code G; Alpha-glucosidases, family 31 of glycosyl hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 31 family [H]

Homologues:

Organism=Homo sapiens, GI88900491, Length=539, Percent_Identity=27.6437847866419, Blast_Score=262, Evalue=1e-69,
Organism=Homo sapiens, GI38202257, Length=539, Percent_Identity=27.6437847866419, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI119393895, Length=563, Percent_Identity=28.0639431616341, Blast_Score=257, Evalue=3e-68,
Organism=Homo sapiens, GI119393893, Length=563, Percent_Identity=28.0639431616341, Blast_Score=257, Evalue=3e-68,
Organism=Homo sapiens, GI119393891, Length=563, Percent_Identity=28.0639431616341, Blast_Score=257, Evalue=3e-68,
Organism=Homo sapiens, GI66346737, Length=533, Percent_Identity=27.0168855534709, Blast_Score=253, Evalue=5e-67,
Organism=Homo sapiens, GI157364974, Length=670, Percent_Identity=26.865671641791, Blast_Score=236, Evalue=6e-62,
Organism=Homo sapiens, GI221316699, Length=596, Percent_Identity=26.006711409396, Blast_Score=224, Evalue=2e-58,
Organism=Homo sapiens, GI310115361, Length=467, Percent_Identity=29.1220556745182, Blast_Score=203, Evalue=4e-52,
Organism=Escherichia coli, GI2367256, Length=588, Percent_Identity=22.7891156462585, Blast_Score=166, Evalue=7e-42,
Organism=Escherichia coli, GI2367323, Length=625, Percent_Identity=20.8, Blast_Score=88, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI71991189, Length=561, Percent_Identity=28.3422459893048, Blast_Score=258, Evalue=6e-69,
Organism=Caenorhabditis elegans, GI17560798, Length=556, Percent_Identity=27.158273381295, Blast_Score=249, Evalue=5e-66,
Organism=Caenorhabditis elegans, GI17560800, Length=556, Percent_Identity=27.158273381295, Blast_Score=248, Evalue=8e-66,
Organism=Caenorhabditis elegans, GI32563849, Length=706, Percent_Identity=24.0793201133144, Blast_Score=193, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI71985706, Length=632, Percent_Identity=25.7911392405063, Blast_Score=189, Evalue=5e-48,
Organism=Saccharomyces cerevisiae, GI6319706, Length=688, Percent_Identity=25.2906976744186, Blast_Score=209, Evalue=8e-55,
Organism=Drosophila melanogaster, GI24643749, Length=543, Percent_Identity=27.4401473296501, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI24643753, Length=543, Percent_Identity=27.4401473296501, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI24643751, Length=543, Percent_Identity=27.4401473296501, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI24643746, Length=543, Percent_Identity=27.4401473296501, Blast_Score=226, Evalue=3e-59,
Organism=Drosophila melanogaster, GI21357605, Length=543, Percent_Identity=27.4401473296501, Blast_Score=226, Evalue=3e-59,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR011013
- InterPro:   IPR000322
- InterPro:   IPR017853 [H]

Pfam domain/function: PF01055 Glyco_hydro_31 [H]

EC number: =3.2.1.20 [H]

Molecular weight: Translated: 84034; Mature: 84034

Theoretical pI: Translated: 5.13; Mature: 5.13

Prosite motif: PS00129 GLYCOSYL_HYDROL_F31_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRINCINNHITKYTFGIPFNTESVVLKEGSEMENQELKYLNFENNTFTLKLKEEDIVYGL
CEEEEECCCCEEEEEECCCCCCEEEEECCCCCCCCCEEEEEECCCEEEEEEECCCEEEEC
GENVRGLNKRGWRYESFCTDDFSHTPEKKSLYGAHNFLMIYGEKTFGIFIDYPGRVKFDV
CCCCCCCCCCCCEECCCCCCCCCCCCCCHHCCCCCEEEEEEECCEEEEEEECCCEEEEEE
GYRRRDELKIEIDDENFALYIIEGDTLKEIAKSFRGLIGESYMAPKWAFGAQQSRWSYKD
CCCCCCCEEEEECCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
SKEVLEVLDNFNESELPLDCIYLDIDYMEDFKNFTINKEAFPDFENFVKEVKEKGVRLIP
HHHHHHHHHCCCCCCCCEEEEEEEEHHHHHHHCCEECCCCCCCHHHHHHHHHHCCCEEEE
IIDAGCKIEEGYDVYEEGVKNGYYCLDEEGKPFVAAVWPGRVHFPDFLNKDARLWFGNKY
EECCCCEECCCCHHHHHHCCCCEEEECCCCCEEEEEECCCCCCCHHHHCCCCEEEECCEE
KVLTDKGIEGFWNDMNEPAIFYSEKRLNEAFEKISEAKGRNLGIYDYFDVKDTFPRLQNS
EEEECCCCCHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHH
MEDYQSFYHRVGNGKIRHDKIHNLFGFNMTRAASEGLENIDENKRFLLFSRASTVGMHRY
HHHHHHHHHHHCCCCEEHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHC
GGIWTGDNMSWWEHIKLNLQMMPNINMCGFIYTGADTGGFGGDTTEDLVIRWSQFSMFTP
CCEEECCCCCCEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHEEEEHHHHHHHH
LFRNHSALGTRHQEPYSFRGESVKVLKNILELRYVMVPYLYSEYMKAILNNEMYFKPLTF
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
EYSDNFVKRVEDQMLLGDSLMVAPIYEQNALGRYVYIPEEMLLWRARKYDDGDYEVLEKG
ECCCHHHHHHHHHHEECCCEEEEEEECCCCCCCEEEECHHHHHHHHCCCCCCCHHHHHCC
HHYVEAKLNEVPIFIRKNKIVTMASKPRKRVEEIDTSELNLIAFVCDKAEYIYYNDDGIT
CEEEEEECCCCEEEEECCEEEEECCCCHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCC
KNYKNGEYEELKIKITKVQSDYEVLVENKNSRVKNLNIKIFDLNKNMIEKEILIQ
CCCCCCCCEEEEEEEEEECCCEEEEEECCCCEEEEEEEEEEECCCHHHHHHHHCC
>Mature Secondary Structure
MRINCINNHITKYTFGIPFNTESVVLKEGSEMENQELKYLNFENNTFTLKLKEEDIVYGL
CEEEEECCCCEEEEEECCCCCCEEEEECCCCCCCCCEEEEEECCCEEEEEEECCCEEEEC
GENVRGLNKRGWRYESFCTDDFSHTPEKKSLYGAHNFLMIYGEKTFGIFIDYPGRVKFDV
CCCCCCCCCCCCEECCCCCCCCCCCCCCHHCCCCCEEEEEEECCEEEEEEECCCEEEEEE
GYRRRDELKIEIDDENFALYIIEGDTLKEIAKSFRGLIGESYMAPKWAFGAQQSRWSYKD
CCCCCCCEEEEECCCCEEEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
SKEVLEVLDNFNESELPLDCIYLDIDYMEDFKNFTINKEAFPDFENFVKEVKEKGVRLIP
HHHHHHHHHCCCCCCCCEEEEEEEEHHHHHHHCCEECCCCCCCHHHHHHHHHHCCCEEEE
IIDAGCKIEEGYDVYEEGVKNGYYCLDEEGKPFVAAVWPGRVHFPDFLNKDARLWFGNKY
EECCCCEECCCCHHHHHHCCCCEEEECCCCCEEEEEECCCCCCCHHHHCCCCEEEECCEE
KVLTDKGIEGFWNDMNEPAIFYSEKRLNEAFEKISEAKGRNLGIYDYFDVKDTFPRLQNS
EEEECCCCCHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHH
MEDYQSFYHRVGNGKIRHDKIHNLFGFNMTRAASEGLENIDENKRFLLFSRASTVGMHRY
HHHHHHHHHHHCCCCEEHHHHHHHHCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHC
GGIWTGDNMSWWEHIKLNLQMMPNINMCGFIYTGADTGGFGGDTTEDLVIRWSQFSMFTP
CCEEECCCCCCEEEEEEEEEECCCCCEEEEEEECCCCCCCCCCCCHHHEEEEHHHHHHHH
LFRNHSALGTRHQEPYSFRGESVKVLKNILELRYVMVPYLYSEYMKAILNNEMYFKPLTF
HHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEE
EYSDNFVKRVEDQMLLGDSLMVAPIYEQNALGRYVYIPEEMLLWRARKYDDGDYEVLEKG
ECCCHHHHHHHHHHEECCCEEEEEEECCCCCCCEEEECHHHHHHHHCCCCCCCHHHHHCC
HHYVEAKLNEVPIFIRKNKIVTMASKPRKRVEEIDTSELNLIAFVCDKAEYIYYNDDGIT
CEEEEEECCCCEEEEECCEEEEECCCCHHHHHHCCCCCCEEEEEEECCCEEEEECCCCCC
KNYKNGEYEELKIKITKVQSDYEVLVENKNSRVKNLNIKIFDLNKNMIEKEILIQ
CCCCCCCCEEEEEEEEEECCCEEEEEECCCCEEEEEEEEEEECCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10945254 [H]