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The map label for this gene is malR [C]

Identifier: 18311322

GI number: 18311322

Start: 2696149

End: 2697162

Strand: Reverse

Name: malR [C]

Synonym: CPE2340

Alternate gene names: 18311322

Gene position: 2697162-2696149 (Counterclockwise)

Preceding gene: 18311323

Following gene: 18311321

Centisome position: 88.97

GC content: 29.09

Gene sequence:

>1014_bases
ATGAATATAAAAGACATAGCAAGGCTTGCTGGCGTTGGTGTTAGTACAGTATCAAGAGTTATAAATGATCATCCAGATGT
AAAGGATGAAACGAGAGAAAAAATCTTAAAAATAATCAAAGAAAGTAATTACATACCTAATAATAGTGCTAGGATTCTTA
AGAAAAATAATACAAATAATATAGGAGTTCTAGTAAAGGGGGTATTTAACCCATTCTTTGCTGAGATGATAAACATTATA
GGTAATAGAATAAATGAAGCTGGCTACACAATGATATTACAGCAAAATGACTATGCCACAGAGGATGATGTGGATAATTT
AATAGCTTTTGTTAAAGAGAAAAGACTTCAAGGTATTATCTGCTTAGGAGGAAACTTTTTAAACATAAATGATGAAAGTT
TTCAATTCTTAGATATTCCAGTAGTTTTAACCTCTGTTAATACACTTTCTAAAGAAAGTAAAAGTAAGTTTTCATCAATA
GGAATAGATAACGTATTAGCAGCTAAGGCTTCAATTCAATATCTTATAGATAAAGGGCATAGAAACATAGGAATTTTATT
AGGAGAAAAAAATGATGTTGGAATAAGTGGATTAAGACTTGAAGGCTATAAAAAAGCTTTAGAGGAAAATAATATACCTT
ATTCAGAAGAAAATGTATTTATAGGTGATTATGATTATAGTGGAGCATATAGAGTAACAAAGGAAATTGTTAATAATAGA
AAAGATATAACAGCTATATTTTCAATATCAGATATTATGGCTGTAGGGGCAGCAAAATCAGTTATAGATCAAGGATTGCA
GGTAGGAGAAGATATTTCTATTATGGGATTTGATGGAATGGATATAAGTAAATATTATAATCCAGGAATTACAACTGTAA
AGCAGCCTAAGAAAAATATGGCTAATAATAGCATAGATTTATTATTAGCTCTTTTAGCTAAAAAGGAAGAGCATAAGCAT
ATAATTTTTGAAACAAAGATAATAGAAAGAGAGTCATGTAAGAAAGTGGTATAG

Upstream 100 bases:

>100_bases
TATTGCTAATGTTTTCAAAGCAGTTTATAATTAAAATGGTATCGTTACCGAAACTATTTCCAAGTTTTTTAAGATTATAG
GGAAAATCAGGAGGAGTTAT

Downstream 100 bases:

>100_bases
TACTTATAATTGGGGGAGATATTATGAGAATTAATTGTATTAATAATCACATAACTAAATATACTTTTGGAATTCCTTTT
AATACTGAGTCAGTTGTTTT

Product: LacI family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MNIKDIARLAGVGVSTVSRVINDHPDVKDETREKILKIIKESNYIPNNSARILKKNNTNNIGVLVKGVFNPFFAEMINII
GNRINEAGYTMILQQNDYATEDDVDNLIAFVKEKRLQGIICLGGNFLNINDESFQFLDIPVVLTSVNTLSKESKSKFSSI
GIDNVLAAKASIQYLIDKGHRNIGILLGEKNDVGISGLRLEGYKKALEENNIPYSEENVFIGDYDYSGAYRVTKEIVNNR
KDITAIFSISDIMAVGAAKSVIDQGLQVGEDISIMGFDGMDISKYYNPGITTVKQPKKNMANNSIDLLLALLAKKEEHKH
IIFETKIIERESCKKVV

Sequences:

>Translated_337_residues
MNIKDIARLAGVGVSTVSRVINDHPDVKDETREKILKIIKESNYIPNNSARILKKNNTNNIGVLVKGVFNPFFAEMINII
GNRINEAGYTMILQQNDYATEDDVDNLIAFVKEKRLQGIICLGGNFLNINDESFQFLDIPVVLTSVNTLSKESKSKFSSI
GIDNVLAAKASIQYLIDKGHRNIGILLGEKNDVGISGLRLEGYKKALEENNIPYSEENVFIGDYDYSGAYRVTKEIVNNR
KDITAIFSISDIMAVGAAKSVIDQGLQVGEDISIMGFDGMDISKYYNPGITTVKQPKKNMANNSIDLLLALLAKKEEHKH
IIFETKIIERESCKKVV
>Mature_337_residues
MNIKDIARLAGVGVSTVSRVINDHPDVKDETREKILKIIKESNYIPNNSARILKKNNTNNIGVLVKGVFNPFFAEMINII
GNRINEAGYTMILQQNDYATEDDVDNLIAFVKEKRLQGIICLGGNFLNINDESFQFLDIPVVLTSVNTLSKESKSKFSSI
GIDNVLAAKASIQYLIDKGHRNIGILLGEKNDVGISGLRLEGYKKALEENNIPYSEENVFIGDYDYSGAYRVTKEIVNNR
KDITAIFSISDIMAVGAAKSVIDQGLQVGEDISIMGFDGMDISKYYNPGITTVKQPKKNMANNSIDLLLALLAKKEEHKH
IIFETKIIERESCKKVV

Specific function: Repressor of glucanotransferase gene expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787948, Length=339, Percent_Identity=33.0383480825959, Blast_Score=184, Evalue=7e-48,
Organism=Escherichia coli, GI1790194, Length=335, Percent_Identity=31.6417910447761, Blast_Score=170, Evalue=1e-43,
Organism=Escherichia coli, GI1790369, Length=309, Percent_Identity=29.4498381877023, Blast_Score=157, Evalue=9e-40,
Organism=Escherichia coli, GI1788474, Length=310, Percent_Identity=29.6774193548387, Blast_Score=142, Evalue=4e-35,
Organism=Escherichia coli, GI1787580, Length=335, Percent_Identity=28.955223880597, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1789202, Length=302, Percent_Identity=30.1324503311258, Blast_Score=138, Evalue=6e-34,
Organism=Escherichia coli, GI1786540, Length=337, Percent_Identity=27.5964391691395, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1789068, Length=332, Percent_Identity=26.2048192771084, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI48994940, Length=310, Percent_Identity=28.0645161290323, Blast_Score=113, Evalue=1e-26,
Organism=Escherichia coli, GI1790715, Length=330, Percent_Identity=27.5757575757576, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1790689, Length=328, Percent_Identity=25.609756097561, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1789456, Length=316, Percent_Identity=23.4177215189873, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI1787906, Length=341, Percent_Identity=21.1143695014663, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1786268, Length=327, Percent_Identity=22.3241590214067, Blast_Score=82, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37482; Mature: 37482

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIKDIARLAGVGVSTVSRVINDHPDVKDETREKILKIIKESNYIPNNSARILKKNNTNN
CCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCC
IGVLVKGVFNPFFAEMINIIGNRINEAGYTMILQQNDYATEDDVDNLIAFVKEKRLQGII
EEEEEEHHHCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCEEE
CLGGNFLNINDESFQFLDIPVVLTSVNTLSKESKSKFSSIGIDNVLAAKASIQYLIDKGH
EECCEEEECCCCCEEEEEEEEHEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
RNIGILLGEKNDVGISGLRLEGYKKALEENNIPYSEENVFIGDYDYSGAYRVTKEIVNNR
CEEEEEEECCCCCCCEEEEEHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHCCC
KDITAIFSISDIMAVGAAKSVIDQGLQVGEDISIMGFDGMDISKYYNPGITTVKQPKKNM
CCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCCCCCCCCCHHHH
ANNSIDLLLALLAKKEEHKHIIFETKIIERESCKKVV
CCCHHHHHHHHHHCCCCCCEEEEEEEECCHHHHCCCC
>Mature Secondary Structure
MNIKDIARLAGVGVSTVSRVINDHPDVKDETREKILKIIKESNYIPNNSARILKKNNTNN
CCHHHHHHHHCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCC
IGVLVKGVFNPFFAEMINIIGNRINEAGYTMILQQNDYATEDDVDNLIAFVKEKRLQGII
EEEEEEHHHCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHCEEE
CLGGNFLNINDESFQFLDIPVVLTSVNTLSKESKSKFSSIGIDNVLAAKASIQYLIDKGH
EECCEEEECCCCCEEEEEEEEHEHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCC
RNIGILLGEKNDVGISGLRLEGYKKALEENNIPYSEENVFIGDYDYSGAYRVTKEIVNNR
CEEEEEEECCCCCCCEEEEEHHHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHCCC
KDITAIFSISDIMAVGAAKSVIDQGLQVGEDISIMGFDGMDISKYYNPGITTVKQPKKNM
CCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHCCCCCCCCCCCHHHH
ANNSIDLLLALLAKKEEHKHIIFETKIIERESCKKVV
CCCHHHHHHHHHHCCCCCCEEEEEEEECCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA