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The map label for this gene is yycG [H]

Identifier: 18311313

GI number: 18311313

Start: 2683722

End: 2685125

Strand: Reverse

Name: yycG [H]

Synonym: CPE2331

Alternate gene names: 18311313

Gene position: 2685125-2683722 (Counterclockwise)

Preceding gene: 18311314

Following gene: 18311311

Centisome position: 88.58

GC content: 26.85

Gene sequence:

>1404_bases
TTGAAGGTAAGAAAATATAAAAGTTTAAATTTTAAGGTTATAGTTCCATCTATAGTTATCATAATAATTGTAACTTTACT
TACTGTGGTCATATCTAAATTTTATTTTGATAAAAAATTTGGTGACTATATTATGATTAAAAATCAGAATACAGTACAAA
ACATTTTGATGGAGCTAAGTGAACAATATTCCGATAATGAGTGGAATTATAAGAATATAGAGAAGATAACTTATAATTCC
TTAGATAAAGGGATTATAGTTGCTTTATATGATAAAGAAGATAAGGAAATAATGAACATAGAAAAAAACTCTAAGGATAA
ATGCAATAGAATTATGAATTTTATAAAAAGTTCTATGGAAGGGAAATATGGCTCTACAACAAGTCAATTTGAACCTGTGT
ATTATCCTTTAATAAAGAGTGGAGAAAAAATTGGAGAGGTTAGGGTAAAATTTTATGGTCCTATATTTTATATGCAGAAT
GAATTAGTTTTTCTGGATATAGTAAATAAGATAATATTAGGTATTGGAGTTTTACTTATTTTAGCATCTACAATAATGGG
ATTTATAATTTCAAGATCCATAACAAGACCAATAAATAAGCTCATGACAAAGGCGAAGTATATTTCTAAAGGAGAGTATG
ACAAGAAAATTGAGATAAATACAGATATTTTAGAGATAAATGATTTGATAAATTCCATAAATAATCTTTCACAGAGTATA
AAAGAGCAAGAGAATATAAGAAAAAGACTTACTGGGGATATTTCTCATGAGTTAAAAACTCCTTTAACAAATATACAGTC
TCACTTAGAGGCAATGATAGATGGCATATGGGAACCTACAGAGGAAAGGTTACTAAGTGTTAAGGAAGAGGCAGAAAGAT
TATCGTCCTTAGTAAGTGATATGCAAAAGTTAAATAAGTATGATGAGTCTTCTATTAAGCTTAAAAAGGATAATGTGAAT
ATAAGTGATATAATTTGCTTTGTAATATTTCAATTTTCTAATTTAGCAAAAAGCAAAAATATAAAGATAGAATATGAAAA
AAAGAATATTAATTTATATTGTGATAAGGATAAAATAACACAGGCTTTAGTAAATATTCTTTCAAATGCTATTAGGTATT
CAAATGAGGGAAGTACTATTTTTATAGAAGAAAAATTAAAAGATAATAAGGTTATAATATCAATAGAAGATCAAGGTATA
GGTATTTCAGAAGAGGATTTAAAATATGTCTTTGAAAGATTCTATAGGGCAGATAAATCTAGAACTAGAGCTACTGGAGG
AACAGGAATAGGACTAACCATAGTTAAATCCATAGTATCTTCTCATGGAGGAGAAGTTAAGTTAGAGAGTAAACTAGGTG
AAGGAAGTAAGTTTACTATAATATTACCTAAAGAAGATATATGA

Upstream 100 bases:

>100_bases
AGGGTTATAGATTCTCACATAAAAAATTTAAGAGGTAAAATAGAAGAAAATACTAGAAAACCTAAGTTCATAGTAACTGT
ATATGGGGTGGGATATAAAT

Downstream 100 bases:

>100_bases
TTATTTTATGGAAAAGTAATTTTATTTATAATGCTATATAAATAAGTAAGATACTTAGAAACTATATAATTTAATACGAA
AGTTTGAATTATATGATTAT

Product: two-component sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 467; Mature: 467

Protein sequence:

>467_residues
MKVRKYKSLNFKVIVPSIVIIIIVTLLTVVISKFYFDKKFGDYIMIKNQNTVQNILMELSEQYSDNEWNYKNIEKITYNS
LDKGIIVALYDKEDKEIMNIEKNSKDKCNRIMNFIKSSMEGKYGSTTSQFEPVYYPLIKSGEKIGEVRVKFYGPIFYMQN
ELVFLDIVNKIILGIGVLLILASTIMGFIISRSITRPINKLMTKAKYISKGEYDKKIEINTDILEINDLINSINNLSQSI
KEQENIRKRLTGDISHELKTPLTNIQSHLEAMIDGIWEPTEERLLSVKEEAERLSSLVSDMQKLNKYDESSIKLKKDNVN
ISDIICFVIFQFSNLAKSKNIKIEYEKKNINLYCDKDKITQALVNILSNAIRYSNEGSTIFIEEKLKDNKVIISIEDQGI
GISEEDLKYVFERFYRADKSRTRATGGTGIGLTIVKSIVSSHGGEVKLESKLGEGSKFTIILPKEDI

Sequences:

>Translated_467_residues
MKVRKYKSLNFKVIVPSIVIIIIVTLLTVVISKFYFDKKFGDYIMIKNQNTVQNILMELSEQYSDNEWNYKNIEKITYNS
LDKGIIVALYDKEDKEIMNIEKNSKDKCNRIMNFIKSSMEGKYGSTTSQFEPVYYPLIKSGEKIGEVRVKFYGPIFYMQN
ELVFLDIVNKIILGIGVLLILASTIMGFIISRSITRPINKLMTKAKYISKGEYDKKIEINTDILEINDLINSINNLSQSI
KEQENIRKRLTGDISHELKTPLTNIQSHLEAMIDGIWEPTEERLLSVKEEAERLSSLVSDMQKLNKYDESSIKLKKDNVN
ISDIICFVIFQFSNLAKSKNIKIEYEKKNINLYCDKDKITQALVNILSNAIRYSNEGSTIFIEEKLKDNKVIISIEDQGI
GISEEDLKYVFERFYRADKSRTRATGGTGIGLTIVKSIVSSHGGEVKLESKLGEGSKFTIILPKEDI
>Mature_467_residues
MKVRKYKSLNFKVIVPSIVIIIIVTLLTVVISKFYFDKKFGDYIMIKNQNTVQNILMELSEQYSDNEWNYKNIEKITYNS
LDKGIIVALYDKEDKEIMNIEKNSKDKCNRIMNFIKSSMEGKYGSTTSQFEPVYYPLIKSGEKIGEVRVKFYGPIFYMQN
ELVFLDIVNKIILGIGVLLILASTIMGFIISRSITRPINKLMTKAKYISKGEYDKKIEINTDILEINDLINSINNLSQSI
KEQENIRKRLTGDISHELKTPLTNIQSHLEAMIDGIWEPTEERLLSVKEEAERLSSLVSDMQKLNKYDESSIKLKKDNVN
ISDIICFVIFQFSNLAKSKNIKIEYEKKNINLYCDKDKITQALVNILSNAIRYSNEGSTIFIEEKLKDNKVIISIEDQGI
GISEEDLKYVFERFYRADKSRTRATGGTGIGLTIVKSIVSSHGGEVKLESKLGEGSKFTIILPKEDI

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=468, Percent_Identity=25.2136752136752, Blast_Score=166, Evalue=3e-42,
Organism=Escherichia coli, GI1786783, Length=300, Percent_Identity=31.6666666666667, Blast_Score=154, Evalue=1e-38,
Organism=Escherichia coli, GI1786600, Length=283, Percent_Identity=28.2685512367491, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1790346, Length=291, Percent_Identity=29.8969072164948, Blast_Score=129, Evalue=3e-31,
Organism=Escherichia coli, GI1787894, Length=311, Percent_Identity=26.6881028938907, Blast_Score=106, Evalue=4e-24,
Organism=Escherichia coli, GI1789149, Length=359, Percent_Identity=23.3983286908078, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1788713, Length=254, Percent_Identity=27.1653543307087, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI1790551, Length=282, Percent_Identity=26.5957446808511, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI87082128, Length=292, Percent_Identity=25, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=28.310502283105, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1788279, Length=302, Percent_Identity=26.8211920529801, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1789808, Length=271, Percent_Identity=25.0922509225092, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI145693157, Length=245, Percent_Identity=22.8571428571429, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1786912, Length=227, Percent_Identity=24.2290748898678, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI87081816, Length=339, Percent_Identity=23.0088495575221, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788549, Length=216, Percent_Identity=25.9259259259259, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI48994928, Length=214, Percent_Identity=24.7663551401869, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1789403, Length=290, Percent_Identity=24.4827586206897, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI1790861, Length=365, Percent_Identity=23.2876712328767, Blast_Score=76, Evalue=5e-15,
Organism=Escherichia coli, GI1787374, Length=306, Percent_Identity=23.5294117647059, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6322044, Length=73, Percent_Identity=43.8356164383562, Blast_Score=68, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53553; Mature: 53553

Theoretical pI: Translated: 8.95; Mature: 8.95

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVRKYKSLNFKVIVPSIVIIIIVTLLTVVISKFYFDKKFGDYIMIKNQNTVQNILMELS
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHH
EQYSDNEWNYKNIEKITYNSLDKGIIVALYDKEDKEIMNIEKNSKDKCNRIMNFIKSSME
HHCCCCCCCCCCHHHHHHCCCCCCEEEEEECCCCCHHHCCCCCCHHHHHHHHHHHHHHHC
GKYGSTTSQFEPVYYPLIKSGEKIGEVRVKFYGPIFYMQNELVFLDIVNKIILGIGVLLI
CCCCCCCCCCCCCHHHHHHCCCHHCEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHH
LASTIMGFIISRSITRPINKLMTKAKYISKGEYDKKIEINTDILEINDLINSINNLSQSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHH
KEQENIRKRLTGDISHELKTPLTNIQSHLEAMIDGIWEPTEERLLSVKEEAERLSSLVSD
HHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
MQKLNKYDESSIKLKKDNVNISDIICFVIFQFSNLAKSKNIKIEYEKKNINLYCDKDKIT
HHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECHHHHH
QALVNILSNAIRYSNEGSTIFIEEKLKDNKVIISIEDQGIGISEEDLKYVFERFYRADKS
HHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCH
RTRATGGTGIGLTIVKSIVSSHGGEVKLESKLGEGSKFTIILPKEDI
HCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEECCCCC
>Mature Secondary Structure
MKVRKYKSLNFKVIVPSIVIIIIVTLLTVVISKFYFDKKFGDYIMIKNQNTVQNILMELS
CCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHH
EQYSDNEWNYKNIEKITYNSLDKGIIVALYDKEDKEIMNIEKNSKDKCNRIMNFIKSSME
HHCCCCCCCCCCHHHHHHCCCCCCEEEEEECCCCCHHHCCCCCCHHHHHHHHHHHHHHHC
GKYGSTTSQFEPVYYPLIKSGEKIGEVRVKFYGPIFYMQNELVFLDIVNKIILGIGVLLI
CCCCCCCCCCCCCHHHHHHCCCHHCEEEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHH
LASTIMGFIISRSITRPINKLMTKAKYISKGEYDKKIEINTDILEINDLINSINNLSQSI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHH
KEQENIRKRLTGDISHELKTPLTNIQSHLEAMIDGIWEPTEERLLSVKEEAERLSSLVSD
HHHHHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
MQKLNKYDESSIKLKKDNVNISDIICFVIFQFSNLAKSKNIKIEYEKKNINLYCDKDKIT
HHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCEEEEECHHHHH
QALVNILSNAIRYSNEGSTIFIEEKLKDNKVIISIEDQGIGISEEDLKYVFERFYRADKS
HHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHCCH
RTRATGGTGIGLTIVKSIVSSHGGEVKLESKLGEGSKFTIILPKEDI
HCCCCCCCCHHHHHHHHHHHCCCCCEEECCCCCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]