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The map label for this gene is xpsE [H]

Identifier: 18311268

GI number: 18311268

Start: 2630122

End: 2631813

Strand: Reverse

Name: xpsE [H]

Synonym: CPE2286

Alternate gene names: 18311268

Gene position: 2631813-2630122 (Counterclockwise)

Preceding gene: 18311269

Following gene: 18311267

Centisome position: 86.82

GC content: 30.56

Gene sequence:

>1692_bases
TTGATTAGTTATCAGAAAAAGCGTTTAGGAGATATACTAATTGAATCGGGAAAGCTTACAGAGGATAGGCTTAAAGAAGC
ATTATTGATTCAGAAGCAAGTTGGCAAGAGGCTTGGAGAGATCTTAGTTGAACAAAACTTTGTTACTGAAGAGGATATAA
TAGAAGTTTTAGAAAAACAATTAAATATTGAAAGAGTAAATCTTGAAATTATAACAATAGATAGAAGAGCTATAAAGATG
ATTTCGGAAAATGTTTGTAGAAAGCATTTAATAGTTCCGTATGAAATAGATGATAATACCATAAAGGTTGCAATGGCAGA
TCCCTTAGATATAGTTGCAATAGATGATGTTGAGATTTCTACAGGTTTAAATGTGCGTCCGTATATAGCTGTAAAACAAT
CTATTCAAAGAACTATAGATATATATTATTCAAACCAAAAGGTTTTATTAGCAGCGGAAGAATTAACAAAAGCTTCTGAT
GAAGAAAGCAATGAACTTAATTTAGACAAAATTGAGGAAATAGACAACTTAGATAATGCTCCTATTGTAAAAATGATAGA
GTATGTTATTAAAAATGCAGTTGAGGAAAGAGCTAGTGATATACATATTGAAACTTATGAAAATATATTAAGAATTAGAT
ATAGAATAGATGGTAAGTTACATACAATATCTACTTTGCCAGTAGATACTCTAGCTCCTTTAGTTACTCGTGTTAAAATC
CTAGCTAACTTAGATATATCAGAGAAAAGACTTCCTCAAGATGGAAGAATTCTTACTAAGGTTGGAGATAAGCAAATAGA
CTTAAGGGTATCTATTCTTCCTATGATAACAGGAGAAAAGATAGTTATAAGAATAATAAATAAGGAAAATTTCATAATTT
CTAAGGAAGGACTTGGACTGAAAAATTTTGAGCTTTCTCTGCTAGACAAAATAACAAAGCATTCTAATGGAATAATTCTT
GTTACTGGTCCTACAGGGAGTGGTAAAACAACAACACTCTATACTATTTTAAATGAGCTAAACACAGAAAGTAAAAATAT
TATTACAATAGAAGATCCTGTTGAAGTATCAATTGAAGGAATTAACCAAGTTAATGTCAATACTAAAGTTGGCTTAACAT
TTGCAACTGGATTAAGGTCTATATTAAGACAAGACCCTGATACCATAATGGTTGGGGAAATAAGAGATACTGAAACGGCT
CAAATAGCAATAAGATCAGCTATTACAGGTCACTTAGTTTTATCAACTTTACATACTAGTGATGCTCCATCTAGTGTTTT
AAGATTAGAAGATATGGGAGTTCAAAGATATTTGATTGCAAATGCTATTAAGGGAGTTATAGCTCAAAGACTTGTTAGAA
AAATTTGTCCAAATTGTGGACAAACATATGAAGCTACACCATATGAAAAGGAAATATTAAATATAGATGTAAATGAAGAA
GTAATACTTCGTAGAGGAAAAGGGTGTGCTTATTGTAATAATACTGGCTATGTAGGTAGAATGGGTATTTATGAAATTAT
GGAAGTAACTAAGGAACATAGAGATGCTATTTTAGAAAATAAAAGTGCAGATATTCTTAAGGAAATTTCAATTAAGCATG
GTATGAGAACTCTTGGACAATCATGTAGAAGTTTAGTCTTGGAGGGGAATACCACAGTTGAAGAAATGTTAAATATAACT
TATGATATGTAA

Upstream 100 bases:

>100_bases
CATAATAATACCAATATATTTTGGTGTGTGAAAAATTTAATATACTAGTTTAGATTAAGTTTTATAGTTAAATTTTTAAC
TTGAAAAGGAGGTATTTTCT

Downstream 100 bases:

>100_bases
TTTGGTGAAAGAAAAGGAGAGGAATTATGGCAAATTTTAAATATAAAGCTATTAATTCAGAAGGGCAAAGAATAGAAGGT
TCTCAAAGTGCTGATTCTGA

Product: secretion system protein E

Products: NA

Alternate protein names: Type II traffic warden ATPase [H]

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MISYQKKRLGDILIESGKLTEDRLKEALLIQKQVGKRLGEILVEQNFVTEEDIIEVLEKQLNIERVNLEIITIDRRAIKM
ISENVCRKHLIVPYEIDDNTIKVAMADPLDIVAIDDVEISTGLNVRPYIAVKQSIQRTIDIYYSNQKVLLAAEELTKASD
EESNELNLDKIEEIDNLDNAPIVKMIEYVIKNAVEERASDIHIETYENILRIRYRIDGKLHTISTLPVDTLAPLVTRVKI
LANLDISEKRLPQDGRILTKVGDKQIDLRVSILPMITGEKIVIRIINKENFIISKEGLGLKNFELSLLDKITKHSNGIIL
VTGPTGSGKTTTLYTILNELNTESKNIITIEDPVEVSIEGINQVNVNTKVGLTFATGLRSILRQDPDTIMVGEIRDTETA
QIAIRSAITGHLVLSTLHTSDAPSSVLRLEDMGVQRYLIANAIKGVIAQRLVRKICPNCGQTYEATPYEKEILNIDVNEE
VILRRGKGCAYCNNTGYVGRMGIYEIMEVTKEHRDAILENKSADILKEISIKHGMRTLGQSCRSLVLEGNTTVEEMLNIT
YDM

Sequences:

>Translated_563_residues
MISYQKKRLGDILIESGKLTEDRLKEALLIQKQVGKRLGEILVEQNFVTEEDIIEVLEKQLNIERVNLEIITIDRRAIKM
ISENVCRKHLIVPYEIDDNTIKVAMADPLDIVAIDDVEISTGLNVRPYIAVKQSIQRTIDIYYSNQKVLLAAEELTKASD
EESNELNLDKIEEIDNLDNAPIVKMIEYVIKNAVEERASDIHIETYENILRIRYRIDGKLHTISTLPVDTLAPLVTRVKI
LANLDISEKRLPQDGRILTKVGDKQIDLRVSILPMITGEKIVIRIINKENFIISKEGLGLKNFELSLLDKITKHSNGIIL
VTGPTGSGKTTTLYTILNELNTESKNIITIEDPVEVSIEGINQVNVNTKVGLTFATGLRSILRQDPDTIMVGEIRDTETA
QIAIRSAITGHLVLSTLHTSDAPSSVLRLEDMGVQRYLIANAIKGVIAQRLVRKICPNCGQTYEATPYEKEILNIDVNEE
VILRRGKGCAYCNNTGYVGRMGIYEIMEVTKEHRDAILENKSADILKEISIKHGMRTLGQSCRSLVLEGNTTVEEMLNIT
YDM
>Mature_563_residues
MISYQKKRLGDILIESGKLTEDRLKEALLIQKQVGKRLGEILVEQNFVTEEDIIEVLEKQLNIERVNLEIITIDRRAIKM
ISENVCRKHLIVPYEIDDNTIKVAMADPLDIVAIDDVEISTGLNVRPYIAVKQSIQRTIDIYYSNQKVLLAAEELTKASD
EESNELNLDKIEEIDNLDNAPIVKMIEYVIKNAVEERASDIHIETYENILRIRYRIDGKLHTISTLPVDTLAPLVTRVKI
LANLDISEKRLPQDGRILTKVGDKQIDLRVSILPMITGEKIVIRIINKENFIISKEGLGLKNFELSLLDKITKHSNGIIL
VTGPTGSGKTTTLYTILNELNTESKNIITIEDPVEVSIEGINQVNVNTKVGLTFATGLRSILRQDPDTIMVGEIRDTETA
QIAIRSAITGHLVLSTLHTSDAPSSVLRLEDMGVQRYLIANAIKGVIAQRLVRKICPNCGQTYEATPYEKEILNIDVNEE
VILRRGKGCAYCNNTGYVGRMGIYEIMEVTKEHRDAILENKSADILKEISIKHGMRTLGQSCRSLVLEGNTTVEEMLNIT
YDM

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=390, Percent_Identity=47.1794871794872, Blast_Score=377, Evalue=1e-106,
Organism=Escherichia coli, GI1786296, Length=384, Percent_Identity=41.6666666666667, Blast_Score=320, Evalue=2e-88,
Organism=Escherichia coli, GI87082188, Length=279, Percent_Identity=34.4086021505376, Blast_Score=124, Evalue=2e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007831
- InterPro:   IPR013369
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E; PF05157 GSPII_E_N [H]

EC number: NA

Molecular weight: Translated: 63307; Mature: 63307

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISYQKKRLGDILIESGKLTEDRLKEALLIQKQVGKRLGEILVEQNFVTEEDIIEVLEKQ
CCCCCHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LNIERVNLEIITIDRRAIKMISENVCRKHLIVPYEIDDNTIKVAMADPLDIVAIDDVEIS
CCEEEEEEEEEEECHHHHHHHHHHHHHHHEEEEEEECCCEEEEEEECCEEEEEECCEEEC
TGLNVRPYIAVKQSIQRTIDIYYSNQKVLLAAEELTKASDEESNELNLDKIEEIDNLDNA
CCCCCCCHHHHHHHHHHEEEEEECCCEEEEEEHHHHCCCCCCCCCCCHHHHHHHHCCCCC
PIVKMIEYVIKNAVEERASDIHIETYENILRIRYRIDGKLHTISTLPVDTLAPLVTRVKI
CHHHHHHHHHHHHHHHHHCCEEHHHHHHHEEEEEEECCEEEEEEECCHHHHHHHHHHHHH
LANLDISEKRLPQDGRILTKVGDKQIDLRVSILPMITGEKIVIRIINKENFIISKEGLGL
HHCCCCCHHHCCCCCCEEEECCCCEEEEEEEEEEEECCCEEEEEEECCCCEEEECCCCCC
KNFELSLLDKITKHSNGIILVTGPTGSGKTTTLYTILNELNTESKNIITIEDPVEVSIEG
CCCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCEEEEEC
INQVNVNTKVGLTFATGLRSILRQDPDTIMVGEIRDTETAQIAIRSAITGHLVLSTLHTS
CEEEECCEEECEEHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHEEECCCC
DAPSSVLRLEDMGVQRYLIANAIKGVIAQRLVRKICPNCGQTYEATPYEKEILNIDVNEE
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCHH
VILRRGKGCAYCNNTGYVGRMGIYEIMEVTKEHRDAILENKSADILKEISIKHGMRTLGQ
HEEECCCCCEEECCCCCEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SCRSLVLEGNTTVEEMLNITYDM
HHHHEEECCCCCHHHHHHHHCCC
>Mature Secondary Structure
MISYQKKRLGDILIESGKLTEDRLKEALLIQKQVGKRLGEILVEQNFVTEEDIIEVLEKQ
CCCCCHHHHHHHEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
LNIERVNLEIITIDRRAIKMISENVCRKHLIVPYEIDDNTIKVAMADPLDIVAIDDVEIS
CCEEEEEEEEEEECHHHHHHHHHHHHHHHEEEEEEECCCEEEEEEECCEEEEEECCEEEC
TGLNVRPYIAVKQSIQRTIDIYYSNQKVLLAAEELTKASDEESNELNLDKIEEIDNLDNA
CCCCCCCHHHHHHHHHHEEEEEECCCEEEEEEHHHHCCCCCCCCCCCHHHHHHHHCCCCC
PIVKMIEYVIKNAVEERASDIHIETYENILRIRYRIDGKLHTISTLPVDTLAPLVTRVKI
CHHHHHHHHHHHHHHHHHCCEEHHHHHHHEEEEEEECCEEEEEEECCHHHHHHHHHHHHH
LANLDISEKRLPQDGRILTKVGDKQIDLRVSILPMITGEKIVIRIINKENFIISKEGLGL
HHCCCCCHHHCCCCCCEEEECCCCEEEEEEEEEEEECCCEEEEEEECCCCEEEECCCCCC
KNFELSLLDKITKHSNGIILVTGPTGSGKTTTLYTILNELNTESKNIITIEDPVEVSIEG
CCCHHHHHHHHHHCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCCCEEEECCCCEEEEEC
INQVNVNTKVGLTFATGLRSILRQDPDTIMVGEIRDTETAQIAIRSAITGHLVLSTLHTS
CEEEECCEEECEEHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHEEECCCC
DAPSSVLRLEDMGVQRYLIANAIKGVIAQRLVRKICPNCGQTYEATPYEKEILNIDVNEE
CCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCHH
VILRRGKGCAYCNNTGYVGRMGIYEIMEVTKEHRDAILENKSADILKEISIKHGMRTLGQ
HEEECCCCCEEECCCCCEECHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
SCRSLVLEGNTTVEEMLNITYDM
HHHHEEECCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1944223; 12024217 [H]