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The map label for this gene is pgi

Identifier: 18311249

GI number: 18311249

Start: 2605305

End: 2606657

Strand: Reverse

Name: pgi

Synonym: CPE2267

Alternate gene names: 18311249

Gene position: 2606657-2605305 (Counterclockwise)

Preceding gene: 18311250

Following gene: 18311248

Centisome position: 85.99

GC content: 33.63

Gene sequence:

>1353_bases
ATGAAAAAAGGATTAGTTGTTGATTTATCAAAAGCAGCTCCATATTTAAAATCTCACGAAGTTGCTTACATGCAAGAAAC
TATAAACCAAGCACACAATAAGTTACATAATGGAACAGGTGCAGGAAATGACTTCTTAGGATGGGTTGACCTACCAGTTA
ATTATGATAAAGATGAGTTTGCTAGAATAAAAGAAGCTGCTAAAAAAATACAAAGTGATTCAGATGTATTAGTTGTTATA
GGAATAGGTGGTTCTTACTTAGGAGCAAGAGCTGCTATAGAAATGTTAACTAACAACTTCTATAACTCTATGTCTAAAGA
TAAGAGAAAAACTCCAGCTATATTCTACGCAGGAAATAACATAAGCTCAAGCTACATGGCTGATTTATTAAAAGCTATTG
ATGGATTAGATGTAAGCTTAAATGTTATATCAAAATCAGGTACTACTACAGAACCTGCTATAGCTTTCAGAATCTTAAAA
GATTACATGGAAAAGAAATACGGAAAAGAAGAAGCTAAGAAGAGAATATATGCTACAACAGACGCTAAGAAAGGTGCTTT
AAAAACTTTAGCTGATGCTGAAGGATATGAAACTTTCGTAATTCCAGATGATGTTGGAGGAAGATTCTCAGTATTAACAG
CAGTTGGATTATTACCAATAGCTGCAGCTGGAATAAACATAGATGAAATGATGGAAGGAGCTGCTGATGCTAGAGAAGAA
TATGCTAATCCTTCATTAGCTGATAACGAATGTTACAAATATGCAGCTGCTAGAAATGCTTTATACAATAAAGGTAAAGC
TATAGAAATATTAGTTAACTATGAGCCATCAGTTCATTACTTCAATGAATGGTGGAAACAATTATATGGAGAATCAGAAG
GAAAAGACAACAAAGGATTATTCCCAGCTGCTGTTGATTTCTCAACTGATTTACACTCAATGGGACAATACATCCAAGAA
GGTAGAAGAGATATCTTCGAAACAGTTATTAATGTAGGATCTCCAAGAGAAGAAATAGTAATCGAAGCTAACGATGAAAA
CATAGATGGATTAAACTTCTTAGCTGGAAAAACTATGGACTATGTTAACAAACAAGCATTCAGAGGAACTTTACTTGCTC
ACAATGATGGAGAAGTTCCAAACGTAGTTGTTAATGTTCCAGAATTAACTCCATACTACTTCGGAAGATTAGTTTACTTC
TTCGAAAAAGCTTGTGGAATCAGTGGATATGTTTTAGGAATAAATCCATTTGACCAACCAGGTGTTGAAGCTTACAAGAA
AAACATGTTTGCTTTACTTGGAAAACCAGGTTTTGAAGATTTAAAAGCTGAGTTAGAAGAAAGATTAAAATAA

Upstream 100 bases:

>100_bases
TTCCAATGGTTTTTGGAGGCTTAATTATTTTTGCGATTATATTATATATATTAATGGCGTGGTTAAAATAAATTTATAAA
CGCTAATGGAGGTAGTAATA

Downstream 100 bases:

>100_bases
TATAAATTTAATTATAAAAAGGAGCTCTTTTTAGAGCTTCTTTTTTGTTTTAAGAGTATAATTTTATTAATATATAAATT
ATTTATTATTTTAAGAGTAT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MKKGLVVDLSKAAPYLKSHEVAYMQETINQAHNKLHNGTGAGNDFLGWVDLPVNYDKDEFARIKEAAKKIQSDSDVLVVI
GIGGSYLGARAAIEMLTNNFYNSMSKDKRKTPAIFYAGNNISSSYMADLLKAIDGLDVSLNVISKSGTTTEPAIAFRILK
DYMEKKYGKEEAKKRIYATTDAKKGALKTLADAEGYETFVIPDDVGGRFSVLTAVGLLPIAAAGINIDEMMEGAADAREE
YANPSLADNECYKYAAARNALYNKGKAIEILVNYEPSVHYFNEWWKQLYGESEGKDNKGLFPAAVDFSTDLHSMGQYIQE
GRRDIFETVINVGSPREEIVIEANDENIDGLNFLAGKTMDYVNKQAFRGTLLAHNDGEVPNVVVNVPELTPYYFGRLVYF
FEKACGISGYVLGINPFDQPGVEAYKKNMFALLGKPGFEDLKAELEERLK

Sequences:

>Translated_450_residues
MKKGLVVDLSKAAPYLKSHEVAYMQETINQAHNKLHNGTGAGNDFLGWVDLPVNYDKDEFARIKEAAKKIQSDSDVLVVI
GIGGSYLGARAAIEMLTNNFYNSMSKDKRKTPAIFYAGNNISSSYMADLLKAIDGLDVSLNVISKSGTTTEPAIAFRILK
DYMEKKYGKEEAKKRIYATTDAKKGALKTLADAEGYETFVIPDDVGGRFSVLTAVGLLPIAAAGINIDEMMEGAADAREE
YANPSLADNECYKYAAARNALYNKGKAIEILVNYEPSVHYFNEWWKQLYGESEGKDNKGLFPAAVDFSTDLHSMGQYIQE
GRRDIFETVINVGSPREEIVIEANDENIDGLNFLAGKTMDYVNKQAFRGTLLAHNDGEVPNVVVNVPELTPYYFGRLVYF
FEKACGISGYVLGINPFDQPGVEAYKKNMFALLGKPGFEDLKAELEERLK
>Mature_450_residues
MKKGLVVDLSKAAPYLKSHEVAYMQETINQAHNKLHNGTGAGNDFLGWVDLPVNYDKDEFARIKEAAKKIQSDSDVLVVI
GIGGSYLGARAAIEMLTNNFYNSMSKDKRKTPAIFYAGNNISSSYMADLLKAIDGLDVSLNVISKSGTTTEPAIAFRILK
DYMEKKYGKEEAKKRIYATTDAKKGALKTLADAEGYETFVIPDDVGGRFSVLTAVGLLPIAAAGINIDEMMEGAADAREE
YANPSLADNECYKYAAARNALYNKGKAIEILVNYEPSVHYFNEWWKQLYGESEGKDNKGLFPAAVDFSTDLHSMGQYIQE
GRRDIFETVINVGSPREEIVIEANDENIDGLNFLAGKTMDYVNKQAFRGTLLAHNDGEVPNVVVNVPELTPYYFGRLVYF
FEKACGISGYVLGINPFDQPGVEAYKKNMFALLGKPGFEDLKAELEERLK

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family

Homologues:

Organism=Escherichia coli, GI1790457, Length=386, Percent_Identity=26.1658031088083, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319673, Length=383, Percent_Identity=25.3263707571802, Blast_Score=77, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): G6PI_CLOP1 (Q0TN51)

Other databases:

- EMBL:   CP000246
- RefSeq:   YP_696939.1
- ProteinModelPortal:   Q0TN51
- SMR:   Q0TN51
- STRING:   Q0TN51
- GeneID:   4202200
- GenomeReviews:   CP000246_GR
- KEGG:   cpf:CPF_2549
- TIGR:   CPF_2549
- eggNOG:   COG0166
- HOGENOM:   HBG615843
- OMA:   YVNDRAY
- ProtClustDB:   PRK14097
- BioCyc:   CPER195103:CPF_2549-MONOMER
- GO:   GO:0005737
- GO:   GO:0006094
- GO:   GO:0006096
- HAMAP:   MF_00473
- InterPro:   IPR001672
- InterPro:   IPR018189
- PANTHER:   PTHR11469
- PRINTS:   PR00662

Pfam domain/function: PF00342 PGI

EC number: =5.3.1.9

Molecular weight: Translated: 49772; Mature: 49772

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1; PS00174 P_GLUCOSE_ISOMERASE_2; PS51463 P_GLUCOSE_ISOMERASE_3

Important sites: ACT_SITE 291-291 ACT_SITE 312-312 ACT_SITE 426-426

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKGLVVDLSKAAPYLKSHEVAYMQETINQAHNKLHNGTGAGNDFLGWVDLPVNYDKDEF
CCCCEEEECHHCCCCHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHH
ARIKEAAKKIQSDSDVLVVIGIGGSYLGARAAIEMLTNNFYNSMSKDKRKTPAIFYAGNN
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
ISSSYMADLLKAIDGLDVSLNVISKSGTTTEPAIAFRILKDYMEKKYGKEEAKKRIYATT
CCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHEEEEC
DAKKGALKTLADAEGYETFVIPDDVGGRFSVLTAVGLLPIAAAGINIDEMMEGAADAREE
CCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
YANPSLADNECYKYAAARNALYNKGKAIEILVNYEPSVHYFNEWWKQLYGESEGKDNKGL
HCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCC
FPAAVDFSTDLHSMGQYIQEGRRDIFETVINVGSPREEIVIEANDENIDGLNFLAGKTMD
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHCCHHH
YVNKQAFRGTLLAHNDGEVPNVVVNVPELTPYYFGRLVYFFEKACGISGYVLGINPFDQP
HHHHHHHCCEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
GVEAYKKNMFALLGKPGFEDLKAELEERLK
CHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MKKGLVVDLSKAAPYLKSHEVAYMQETINQAHNKLHNGTGAGNDFLGWVDLPVNYDKDEF
CCCCEEEECHHCCCCHHHCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCHHHH
ARIKEAAKKIQSDSDVLVVIGIGGSYLGARAAIEMLTNNFYNSMSKDKRKTPAIFYAGNN
HHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
ISSSYMADLLKAIDGLDVSLNVISKSGTTTEPAIAFRILKDYMEKKYGKEEAKKRIYATT
CCHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHEEEEC
DAKKGALKTLADAEGYETFVIPDDVGGRFSVLTAVGLLPIAAAGINIDEMMEGAADAREE
CCCCHHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
YANPSLADNECYKYAAARNALYNKGKAIEILVNYEPSVHYFNEWWKQLYGESEGKDNKGL
HCCCCCCCHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCCC
FPAAVDFSTDLHSMGQYIQEGRRDIFETVINVGSPREEIVIEANDENIDGLNFLAGKTMD
CCEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCHHHHCCHHH
YVNKQAFRGTLLAHNDGEVPNVVVNVPELTPYYFGRLVYFFEKACGISGYVLGINPFDQP
HHHHHHHCCEEEECCCCCCCEEEEECCCCCHHHHHHHHHHHHHHCCCCEEEEECCCCCCC
GVEAYKKNMFALLGKPGFEDLKAELEERLK
CHHHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA