Click here to switch to the map view.

The map label for this gene is lytS [H]

Identifier: 18309909

GI number: 18309909

Start: 1125438

End: 1126670

Strand: Direct

Name: lytS [H]

Synonym: CPE0927

Alternate gene names: 18309909

Gene position: 1125438-1126670 (Clockwise)

Preceding gene: 18309908

Following gene: 18309910

Centisome position: 37.13

GC content: 28.87

Gene sequence:

>1233_bases
ATGGCAAATTTATTAGATATTAGAGAGATTTTAGATGTTAATTCCTTTCAAAAAATACAAGATGATATAGCTAAAGCAAC
TGAGTTTGCTATGATTACAGTAGATTACAAAGGAATACCAGTTACTAAGCATAGTAGATGTAGTGAGTTTTGTAGATTAA
TAAGAGAACAAAAAGAGTTCTCGAAATTATGTGAAAAATGTGATTCAAGAGGTGGATTAGAAGCTGCTAGAGAGGGAAGT
TTTTACATATATAAATGTCATAGAGGTCTTGTGGATGTGGCTGTTCCAATAATAATTGATGGACAATATCTAGGGGCAGT
TATGGTAGGACAAGTTTTATTGATGGATGCAGATGACCATGAATTAGAAGCTGTTTTGACTAAGGAGTTAGAATATGATT
CAGAAATAAAAGATAAAATTATTGATGCATATGAAAAAATACCAGTTCTTAGTTTTGATAAAATAAAAGCTGTTTCAGAG
ATGATGTCTCATGTAAGCAATTACATTGTTGAGGAAGCCTTACTTAAAAGAACTCAAAATGAGATTTATACAAAAAATAT
AGAAATTGCAAGAGCAGAGAGAAGTAAGTTAGAACTTGAAGAGGAATACAAAGCTTGCCAGCTAAAAGCTCTTCAATCTC
AAATAAATCCACATTTTTTATTTAATGTATTAAATAGCATAGCATCTTTAGCAATTATAGAGGATGCCCCTAAAACTCAA
GAAGTAATTTATAATTTGTCGTATATTTTAAGGTACACTTTAAAGAAAGCTAATAAAATTGTAAGACTTAGTGAAGAAAT
AAATCATGTTAAGGCATATTTAAAAATTCAAAAGGTTCGTTTTGGTGAAAGAATACAATATAATATAGATTTTGATGAAG
AGGATTCAAATGTACAAATTCCATTTATGGCACTTCAAGTTTTTGTTGAAAATGCAGTTTTGCATGGAATTGAGGAAAAA
GAACAGGGAGGAGTCATAAACCTATCAATTAAGAGTAGAGGAGAGGACATGATTATTACTATTTCTGATGATGGTGTTGG
AATATCAGTTGAAAAACTCTGTGAAATTAGAAATGAAATAAAAAGTAGAGATAAACTAGACTTAGATAAAGTTGGAATAA
ATAATGTAAATAAGAGAATGTTTCATTATTATGGTGAAGAATATAGTATAAATATAGATAGTAAAGTTAAAAAAGGTACT
AAAGTAGAAATTATAATACCTAGAAAACTTTAA

Upstream 100 bases:

>100_bases
TAACTTTAAAAATACGTTATTTAATATTATGTTTTTAAGTATTATTTTTTTATAGTAAAATATAGTGTGTATATTATTAA
AGCTCTTAAGAGGAGGAAAT

Downstream 100 bases:

>100_bases
ATAAAGGAAGTGTATTTTTGTGTTTAGCATAATGGTTGCTGATGATGAACAATTAGAAAGAAGAGTTTTAACCTCTATAT
TAAAAAAGAATGTAAGAGTT

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 410; Mature: 409

Protein sequence:

>410_residues
MANLLDIREILDVNSFQKIQDDIAKATEFAMITVDYKGIPVTKHSRCSEFCRLIREQKEFSKLCEKCDSRGGLEAAREGS
FYIYKCHRGLVDVAVPIIIDGQYLGAVMVGQVLLMDADDHELEAVLTKELEYDSEIKDKIIDAYEKIPVLSFDKIKAVSE
MMSHVSNYIVEEALLKRTQNEIYTKNIEIARAERSKLELEEEYKACQLKALQSQINPHFLFNVLNSIASLAIIEDAPKTQ
EVIYNLSYILRYTLKKANKIVRLSEEINHVKAYLKIQKVRFGERIQYNIDFDEEDSNVQIPFMALQVFVENAVLHGIEEK
EQGGVINLSIKSRGEDMIITISDDGVGISVEKLCEIRNEIKSRDKLDLDKVGINNVNKRMFHYYGEEYSINIDSKVKKGT
KVEIIIPRKL

Sequences:

>Translated_410_residues
MANLLDIREILDVNSFQKIQDDIAKATEFAMITVDYKGIPVTKHSRCSEFCRLIREQKEFSKLCEKCDSRGGLEAAREGS
FYIYKCHRGLVDVAVPIIIDGQYLGAVMVGQVLLMDADDHELEAVLTKELEYDSEIKDKIIDAYEKIPVLSFDKIKAVSE
MMSHVSNYIVEEALLKRTQNEIYTKNIEIARAERSKLELEEEYKACQLKALQSQINPHFLFNVLNSIASLAIIEDAPKTQ
EVIYNLSYILRYTLKKANKIVRLSEEINHVKAYLKIQKVRFGERIQYNIDFDEEDSNVQIPFMALQVFVENAVLHGIEEK
EQGGVINLSIKSRGEDMIITISDDGVGISVEKLCEIRNEIKSRDKLDLDKVGINNVNKRMFHYYGEEYSINIDSKVKKGT
KVEIIIPRKL
>Mature_409_residues
ANLLDIREILDVNSFQKIQDDIAKATEFAMITVDYKGIPVTKHSRCSEFCRLIREQKEFSKLCEKCDSRGGLEAAREGSF
YIYKCHRGLVDVAVPIIIDGQYLGAVMVGQVLLMDADDHELEAVLTKELEYDSEIKDKIIDAYEKIPVLSFDKIKAVSEM
MSHVSNYIVEEALLKRTQNEIYTKNIEIARAERSKLELEEEYKACQLKALQSQINPHFLFNVLNSIASLAIIEDAPKTQE
VIYNLSYILRYTLKKANKIVRLSEEINHVKAYLKIQKVRFGERIQYNIDFDEEDSNVQIPFMALQVFVENAVLHGIEEKE
QGGVINLSIKSRGEDMIITISDDGVGISVEKLCEIRNEIKSRDKLDLDKVGINNVNKRMFHYYGEEYSINIDSKVKKGTK
VEIIIPRKL

Specific function: Member of the two-component regulatory system lytS/lytT that probably regulates genes involved in cell wall metabolism [H]

COG id: COG2972

COG function: function code T; Predicted signal transduction protein with a C-terminal ATPase domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788723, Length=231, Percent_Identity=33.7662337662338, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1788446, Length=229, Percent_Identity=30.5676855895196, Blast_Score=121, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR010559
- InterPro:   IPR005467
- InterPro:   IPR011620 [H]

Pfam domain/function: PF07694 5TM-5TMR_LYT; PF01590 GAF; PF02518 HATPase_c; PF06580 His_kinase [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 47017; Mature: 46886

Theoretical pI: Translated: 5.30; Mature: 5.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANLLDIREILDVNSFQKIQDDIAKATEFAMITVDYKGIPVTKHSRCSEFCRLIREQKEF
CCCHHHHHHHHCCCHHHHHHHHHHHHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
SKLCEKCDSRGGLEAAREGSFYIYKCHRGLVDVAVPIIIDGQYLGAVMVGQVLLMDADDH
HHHHHHHCCCCCCCHHCCCCEEEEEECCCHHHEEEEEEECCHHHHHHHHHHEEEECCCCH
ELEAVLTKELEYDSEIKDKIIDAYEKIPVLSFDKIKAVSEMMSHVSNYIVEEALLKRTQN
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIYTKNIEIARAERSKLELEEEYKACQLKALQSQINPHFLFNVLNSIASLAIIEDAPKTQ
HHHHCCEEEEECHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEHCCCCCCHH
EVIYNLSYILRYTLKKANKIVRLSEEINHVKAYLKIQKVRFGERIQYNIDFDEEDSNVQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCCCCCEEE
PFMALQVFVENAVLHGIEEKEQGGVINLSIKSRGEDMIITISDDGVGISVEKLCEIRNEI
HHHHHHHHHHHHHHHCCCHHCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHH
KSRDKLDLDKVGINNVNKRMFHYYGEEYSINIDSKVKKGTKVEIIIPRKL
HCCCCCCHHHCCCCHHHHHHHHHCCCEEEEECCHHHCCCCEEEEEECCCC
>Mature Secondary Structure 
ANLLDIREILDVNSFQKIQDDIAKATEFAMITVDYKGIPVTKHSRCSEFCRLIREQKEF
CCHHHHHHHHCCCHHHHHHHHHHHHHEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHH
SKLCEKCDSRGGLEAAREGSFYIYKCHRGLVDVAVPIIIDGQYLGAVMVGQVLLMDADDH
HHHHHHHCCCCCCCHHCCCCEEEEEECCCHHHEEEEEEECCHHHHHHHHHHEEEECCCCH
ELEAVLTKELEYDSEIKDKIIDAYEKIPVLSFDKIKAVSEMMSHVSNYIVEEALLKRTQN
HHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EIYTKNIEIARAERSKLELEEEYKACQLKALQSQINPHFLFNVLNSIASLAIIEDAPKTQ
HHHHCCEEEEECHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHEEHCCCCCCHH
EVIYNLSYILRYTLKKANKIVRLSEEINHVKAYLKIQKVRFGERIQYNIDFDEEDSNVQI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEEEEECCCCCCCCEEE
PFMALQVFVENAVLHGIEEKEQGGVINLSIKSRGEDMIITISDDGVGISVEKLCEIRNEI
HHHHHHHHHHHHHHHCCCHHCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHH
KSRDKLDLDKVGINNVNKRMFHYYGEEYSINIDSKVKKGTKVEIIIPRKL
HCCCCCCHHHCCCCHHHHHHHHHCCCEEEEECCHHHCCCCEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]