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The map label for this gene is tISRso8b [C]

Identifier: 17546986

GI number: 17546986

Start: 2458072

End: 2458962

Strand: Reverse

Name: tISRso8b [C]

Synonym: RSc2267

Alternate gene names: 17546986

Gene position: 2458962-2458072 (Counterclockwise)

Preceding gene: 17546987

Following gene: 17546985

Centisome position: 66.16

GC content: 62.07

Gene sequence:

>891_bases
GTGAAGTACGCCTGGATTGACCAGCAGTGTCGGCACTATCCGCTGTCGGCGCTGTGCGGGGTCCTCTCGGTCAGCGTCAA
CGGCTATCGTGCCTGGAGGCGAGGCGGCACGCCCGAGCGCAAGCGGCTCACCGACACGCAATTGCTCACATTGATTCGGG
CCATCCATGCGCAGTTCAAGGGCGCCTATGGCTCGCCGCGCATGACCGAAGAGATTCGCGCACGCGGGTTCCCGGCCAGC
AAAGCGCGCGTGGAACGCCTGATGAGCCAGAACGGCATCCGGGCACGCCACAAGCGCCGTTATCGGGTCACGACCGATTC
CAGGCACAAGCTGCCGGTCGCGCCGAACCTGCTGAACCGCGAGTTCACGCCGGCCGAGCCGAATCAGGTGTTCAGTTCGG
ACATCACATACATCTGGACCGACGAGGGCTGGCTGTATCTGGCCGTGGTGCTGGACCTGTTCAATCGGGAAGTCATGGGT
TGGTCCATCAAGCCGCGCATGACGGCAGACCTGGTGACCGACGCACTGACGATGGCGTGGTTCCGCCGCAAGCCCGCGCC
CGGCGCGCTGCATCATTCGGACCGTGGCAGCCAGTACGCGAGCCACGAATTCCAGCGCAAGCTGGCCGAATACGGCATGC
GCTGTTCGATGAGCCGCAAGGGAAATTGTTGGGACAACGCACCGACTGAGAGCTTCTTCAACAGCCTGAAGAACGAACGG
GTGCATGCCACGCGCTACCGGACGCATCAGGAGGCTGCGGCGGACCTGTTCGAATACATCGAAGTGTTTTATAACCGCAG
TCGCCGTCATTCGTCGCTCGGCTTTGTCTCGCCAGCTCAGTTCATGCAGGACTGGCTCAAGGCTCAACAGGTGAAGGAAA
CGGCTGCATAA

Upstream 100 bases:

>100_bases
AGCAGATGGAGCTCTCGCGCCTGCGCGCCGAGAACAAGCGGCTGCAAATGGAACTCGAAATCGCAAAAAAGGCGGCGGCG
TACTTCGCGAAAGACCTGCT

Downstream 100 bases:

>100_bases
CCCAGGGCCTCTGGAAGGCGAAAAACAGAGGGAAGGTCAGTATGAAGAGGCGTTCAAGCGCCAAGTAGTTCAGGAGTATT
TGAGGGGGGCCGTTGGGACC

Product: ISRSO8-transposase orfB protein

Products: NA

Alternate protein names: ISO-S3 31 kDa protein [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MKYAWIDQQCRHYPLSALCGVLSVSVNGYRAWRRGGTPERKRLTDTQLLTLIRAIHAQFKGAYGSPRMTEEIRARGFPAS
KARVERLMSQNGIRARHKRRYRVTTDSRHKLPVAPNLLNREFTPAEPNQVFSSDITYIWTDEGWLYLAVVLDLFNREVMG
WSIKPRMTADLVTDALTMAWFRRKPAPGALHHSDRGSQYASHEFQRKLAEYGMRCSMSRKGNCWDNAPTESFFNSLKNER
VHATRYRTHQEAAADLFEYIEVFYNRSRRHSSLGFVSPAQFMQDWLKAQQVKETAA

Sequences:

>Translated_296_residues
MKYAWIDQQCRHYPLSALCGVLSVSVNGYRAWRRGGTPERKRLTDTQLLTLIRAIHAQFKGAYGSPRMTEEIRARGFPAS
KARVERLMSQNGIRARHKRRYRVTTDSRHKLPVAPNLLNREFTPAEPNQVFSSDITYIWTDEGWLYLAVVLDLFNREVMG
WSIKPRMTADLVTDALTMAWFRRKPAPGALHHSDRGSQYASHEFQRKLAEYGMRCSMSRKGNCWDNAPTESFFNSLKNER
VHATRYRTHQEAAADLFEYIEVFYNRSRRHSSLGFVSPAQFMQDWLKAQQVKETAA
>Mature_296_residues
MKYAWIDQQCRHYPLSALCGVLSVSVNGYRAWRRGGTPERKRLTDTQLLTLIRAIHAQFKGAYGSPRMTEEIRARGFPAS
KARVERLMSQNGIRARHKRRYRVTTDSRHKLPVAPNLLNREFTPAEPNQVFSSDITYIWTDEGWLYLAVVLDLFNREVMG
WSIKPRMTADLVTDALTMAWFRRKPAPGALHHSDRGSQYASHEFQRKLAEYGMRCSMSRKGNCWDNAPTESFFNSLKNER
VHATRYRTHQEAAADLFEYIEVFYNRSRRHSSLGFVSPAQFMQDWLKAQQVKETAA

Specific function: Involved in the transposition of the insertion sequence is3 [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=233, Percent_Identity=32.1888412017167, Blast_Score=134, Evalue=1e-31,
Organism=Escherichia coli, GI1788405, Length=286, Percent_Identity=43.006993006993, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1787263, Length=286, Percent_Identity=43.006993006993, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1786753, Length=286, Percent_Identity=43.006993006993, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1786570, Length=286, Percent_Identity=43.006993006993, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1786490, Length=286, Percent_Identity=43.006993006993, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1789981, Length=231, Percent_Identity=34.6320346320346, Blast_Score=132, Evalue=4e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 34368; Mature: 34368

Theoretical pI: Translated: 10.48; Mature: 10.48

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYAWIDQQCRHYPLSALCGVLSVSVNGYRAWRRGGTPERKRLTDTQLLTLIRAIHAQFK
CCCCCCCHHHHCCCHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
GAYGSPRMTEEIRARGFPASKARVERLMSQNGIRARHKRRYRVTTDSRHKLPVAPNLLNR
CCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHCCCEECCCCCCCCCCCCCHHHCC
EFTPAEPNQVFSSDITYIWTDEGWLYLAVVLDLFNREVMGWSIKPRMTADLVTDALTMAW
CCCCCCCHHHHHCCCCEEEECCCHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHH
FRRKPAPGALHHSDRGSQYASHEFQRKLAEYGMRCSMSRKGNCWDNAPTESFFNSLKNER
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCHHHHHHHHHCCC
VHATRYRTHQEAAADLFEYIEVFYNRSRRHSSLGFVSPAQFMQDWLKAQQVKETAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKYAWIDQQCRHYPLSALCGVLSVSVNGYRAWRRGGTPERKRLTDTQLLTLIRAIHAQFK
CCCCCCCHHHHCCCHHHHHHHHHHCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHC
GAYGSPRMTEEIRARGFPASKARVERLMSQNGIRARHKRRYRVTTDSRHKLPVAPNLLNR
CCCCCCCHHHHHHHCCCCHHHHHHHHHHHHCCHHHHHCCCEECCCCCCCCCCCCCHHHCC
EFTPAEPNQVFSSDITYIWTDEGWLYLAVVLDLFNREVMGWSIKPRMTADLVTDALTMAW
CCCCCCCHHHHHCCCCEEEECCCHHHHHHHHHHHCCHHCCCCCCCCHHHHHHHHHHHHHH
FRRKPAPGALHHSDRGSQYASHEFQRKLAEYGMRCSMSRKGNCWDNAPTESFFNSLKNER
HHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCEECCCCCCCCCCCCCHHHHHHHHHCCC
VHATRYRTHQEAAADLFEYIEVFYNRSRRHSSLGFVSPAQFMQDWLKAQQVKETAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2824781 [H]