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The map label for this gene is phnU [H]

Identifier: 17546511

GI number: 17546511

Start: 1927454

End: 1928302

Strand: Direct

Name: phnU [H]

Synonym: RSc1792

Alternate gene names: 17546511

Gene position: 1927454-1928302 (Clockwise)

Preceding gene: 17546510

Following gene: 17546512

Centisome position: 51.86

GC content: 72.67

Gene sequence:

>849_bases
ATGGCCGCCGCCGCACGCTCGCTGCCGGACGACGCCGTGCTGCCCGCGCGGTGGCGGGCGGCGCTGCTCGCGCCCGCCGT
CGCGCTGTTCTGCGCCTTCTGGCTGCTGCCGATGGCGGCGCTGCTGCGCGTGAGCGGCAGCGAGGGGCTGCTGGCCACCT
ACACCGCCGCGCTGACCACGCCGCGCTACCTGGGCAGCCTGGTCTCGACGGTGGTGCTGTCGGCGGCGGTGACGCTGGCG
ACGCTGGTGCTGTCGAGCGTCGCCGGGCTGTTCCTGGTGCGCCACGCGGTGCCGGGCAAGCGGCTGATCACGGCCATGCT
GACCTTTCCGCTGGCGTTTCCCGGCGTGGTGGTGGGCTTCATGGTGATCCTGCTGGCCGGGCGCCAGGGCCTGCTGGGCG
ACCTGACGCTGCGGCTGGCCGGCGAGAAATGGGTGTTCGCCTATTCGATCGGCGGGCTGTTTCTCGGCTACCTGTATTTC
TCCATCCCGCGCGTGGTGCTGACGGTGATGGCGGCGGCGGAAAAGCTCGACCGCTCGCTGGAGGAGGCGGCACGCTCGCT
GGGCGCGTCGTCGTGGCAGGTGACGCGCGACGTGCTGGTGCCGGGGCTGGCGCCCGCGCTGATCGCCTCCGGCGCGATCT
GCTTCGCCACCTCGATGGGGGCGTTCGGCACCGCCTTCACGCTCGCCACCGACATCGACGTGCTGCCGATGACGATCTAC
ACCGAATTCACCCTCAACGCCGGCATGGCCATGGCGGCGGCGCTGTCGGTGGTGCTGGGCGCGGTGACGTGGCTGGTACT
GGCGGCGGCCCGCGTGGCCAGCGGCGGGCAGGCGGGAGCCGCGGCATGA

Upstream 100 bases:

>100_bases
CGGCCAGCGAGTACGCCCGCGTGAAGACGGTCGACTTCAACCAGATGGCGGCGCGCCAGCAGGCCTTCGGCACGCGCTAC
CTGGACGAGGTGCGCTGAGC

Downstream 100 bases:

>100_bases
AGCGCCTGCTGCCGATGGCGCAGTGGCTGGTGACGCTGCTGCTGTGCCTGTTCCTGATCGTGCCGGTGGCGCTGTCGATG
GCCGTGGGGCTGACGCGCAA

Product: transport system permease transmembrane ABC transporter protein

Products: ADP; phosphate; S2O32- [Cytoplasm]; SO42- [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MAAAARSLPDDAVLPARWRAALLAPAVALFCAFWLLPMAALLRVSGSEGLLATYTAALTTPRYLGSLVSTVVLSAAVTLA
TLVLSSVAGLFLVRHAVPGKRLITAMLTFPLAFPGVVVGFMVILLAGRQGLLGDLTLRLAGEKWVFAYSIGGLFLGYLYF
SIPRVVLTVMAAAEKLDRSLEEAARSLGASSWQVTRDVLVPGLAPALIASGAICFATSMGAFGTAFTLATDIDVLPMTIY
TEFTLNAGMAMAAALSVVLGAVTWLVLAAARVASGGQAGAAA

Sequences:

>Translated_282_residues
MAAAARSLPDDAVLPARWRAALLAPAVALFCAFWLLPMAALLRVSGSEGLLATYTAALTTPRYLGSLVSTVVLSAAVTLA
TLVLSSVAGLFLVRHAVPGKRLITAMLTFPLAFPGVVVGFMVILLAGRQGLLGDLTLRLAGEKWVFAYSIGGLFLGYLYF
SIPRVVLTVMAAAEKLDRSLEEAARSLGASSWQVTRDVLVPGLAPALIASGAICFATSMGAFGTAFTLATDIDVLPMTIY
TEFTLNAGMAMAAALSVVLGAVTWLVLAAARVASGGQAGAAA
>Mature_281_residues
AAAARSLPDDAVLPARWRAALLAPAVALFCAFWLLPMAALLRVSGSEGLLATYTAALTTPRYLGSLVSTVVLSAAVTLAT
LVLSSVAGLFLVRHAVPGKRLITAMLTFPLAFPGVVVGFMVILLAGRQGLLGDLTLRLAGEKWVFAYSIGGLFLGYLYFS
IPRVVLTVMAAAEKLDRSLEEAARSLGASSWQVTRDVLVPGLAPALIASGAICFATSMGAFGTAFTLATDIDVLPMTIYT
EFTLNAGMAMAAALSVVLGAVTWLVLAAARVASGGQAGAAA

Specific function: Probably part of the phnSTUV complex (TC 3.A.1.11.5) involved in 2-aminoethylphosphonate import. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0555

COG function: function code O; ABC-type sulfate transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788764, Length=211, Percent_Identity=30.3317535545024, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786980, Length=205, Percent_Identity=34.1463414634146, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI87082099, Length=210, Percent_Identity=28.5714285714286, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017636
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 29049; Mature: 28918

Theoretical pI: Translated: 9.48; Mature: 9.48

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAAARSLPDDAVLPARWRAALLAPAVALFCAFWLLPMAALLRVSGSEGLLATYTAALTT
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
PRYLGSLVSTVVLSAAVTLATLVLSSVAGLFLVRHAVPGKRLITAMLTFPLAFPGVVVGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
MVILLAGRQGLLGDLTLRLAGEKWVFAYSIGGLFLGYLYFSIPRVVLTVMAAAEKLDRSL
HHHHHHCCCCCHHHHHHEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEAARSLGASSWQVTRDVLVPGLAPALIASGAICFATSMGAFGTAFTLATDIDVLPMTIY
HHHHHHCCCCCHHHHHHHHCCCHHHHHHHCCHHHHHHHCCCHHHHHHHHHCCCHHHHHHH
TEFTLNAGMAMAAALSVVLGAVTWLVLAAARVASGGQAGAAA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
AAAARSLPDDAVLPARWRAALLAPAVALFCAFWLLPMAALLRVSGSEGLLATYTAALTT
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCC
PRYLGSLVSTVVLSAAVTLATLVLSSVAGLFLVRHAVPGKRLITAMLTFPLAFPGVVVGF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
MVILLAGRQGLLGDLTLRLAGEKWVFAYSIGGLFLGYLYFSIPRVVLTVMAAAEKLDRSL
HHHHHHCCCCCHHHHHHEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EEAARSLGASSWQVTRDVLVPGLAPALIASGAICFATSMGAFGTAFTLATDIDVLPMTIY
HHHHHHCCCCCHHHHHHHHCCCHHHHHHHCCHHHHHHHCCCHHHHHHHHHCCCHHHHHHH
TEFTLNAGMAMAAALSVVLGAVTWLVLAAARVASGGQAGAAA
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; S2O32- [Periplasm]; H2O; SO42- [Periplasm]; ATP [C]

Specific reaction: ATP + S2O32- [Periplasm] + H2O = ADP + phosphate + S2O32- [Cytoplasm] SO42- [Periplasm] + H2O + ATP = SO42- [Cytoplasm] + phosphate + ADP [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA