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The map label for this gene is yfmJ [H]

Identifier: 17546485

GI number: 17546485

Start: 1893185

End: 1894195

Strand: Direct

Name: yfmJ [H]

Synonym: RSc1766

Alternate gene names: 17546485

Gene position: 1893185-1894195 (Clockwise)

Preceding gene: 17546484

Following gene: 17546486

Centisome position: 50.94

GC content: 67.16

Gene sequence:

>1011_bases
ATGTCGAACACGTATCAACGCATCGTCCTGGCTTCCCGTCCGGAGGGGGCCGTCACGCCGGACAACTTCCGGCTGGAAAC
GGCGCAGATCCCCGAGCTCCAGGACGGCCAGGTGCTGGTGCGCAACCATTTCCTGTCGCTCGATCCGTACATGCGCGGCC
GCATGAACGACAGCAAATCGTACGCGCAGCCGCAGCCGCTGGGCGAGGTGATGATCGGCGGCACGGTGGGCGTGGTGGAA
GCGTCCAGGAACCCGGCGTATGCCGTGGGCGACAACGTGGTCGGCATGTTCGGCTGGCAGGAGGTCGGCATCTCCGACGG
GCGCGGCATGCAGAAGGTGGACACGCGCCACGTGCCGCTGTCGGCCTACCTGGGCTCGGTCGGCATGCCGGGTGTGACGG
CATGGTACGGCCTGAACCGGATCATGCACCCCAAGCCCGGCCAGACCGTGGCGGTGAGCGCGGCCTCCGGCGCGGTCGGC
AGCGTGGTCGGCCAGCTCGCCAAGCTCAAGGGCTGCCGCGCCGTGGGCTTTGCCGGCGGCAAGGACAAGTGCGACTACGT
GGTCAATGAGCTGGGCTTCGACGCCTGCATCGACTACAAGGCCGCCAAGGACCCGAAGGAACTGTACGCGATGCTCAAGG
AGGCCACGCCCGACGGCATCGATGCCTATTTCGAGAACGTCGGCGGCGACATCCTGGACGCCGTGCTGCGCCGCATGAAC
CCGTTCGGCCGCATCGCCATGTGCGGCATGATCGCCGGCTATGACGGCCAGCCGCTGCCGCTGCAGAACCCGCAGTTGAT
CCTGGTCTCGCGCCTGACCGTCGAGGGCTTCATCGTGTCCGAGCACATGGATGTGTGGCCCGAGGCACTGCGCGAGCTGG
GCGGCAGCGTGGCCCAGGGCAAACTGAAGTTCCGCGAGAGCGTGGCGCAGGGGCTGGCGAGCGCGCCGGAGGCCTTCATC
GGCCTGCTCAAGGGCAAGAATTTCGGCAAGCAGCTGGTGAAGCTGGTCTAA

Upstream 100 bases:

>100_bases
AACGCCGTCAACGATCCGGTCACGCACCGGGCCTACCGCGCGCTGGCCGACTTCCTGATGCAGCACAAGTGACCCATCCC
GATCTCTAGGAGCGCTACTC

Downstream 100 bases:

>100_bases
GTTGGGAAGTGTGCGGACTGTCAGGCCGTTGACAGTCCGCCGGGCACGGGCCGCAACGGAATGACCCAGCCACGACGACA
GCGCGAAGGAGGCACCATGA

Product: NADP-dependent oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MSNTYQRIVLASRPEGAVTPDNFRLETAQIPELQDGQVLVRNHFLSLDPYMRGRMNDSKSYAQPQPLGEVMIGGTVGVVE
ASRNPAYAVGDNVVGMFGWQEVGISDGRGMQKVDTRHVPLSAYLGSVGMPGVTAWYGLNRIMHPKPGQTVAVSAASGAVG
SVVGQLAKLKGCRAVGFAGGKDKCDYVVNELGFDACIDYKAAKDPKELYAMLKEATPDGIDAYFENVGGDILDAVLRRMN
PFGRIAMCGMIAGYDGQPLPLQNPQLILVSRLTVEGFIVSEHMDVWPEALRELGGSVAQGKLKFRESVAQGLASAPEAFI
GLLKGKNFGKQLVKLV

Sequences:

>Translated_336_residues
MSNTYQRIVLASRPEGAVTPDNFRLETAQIPELQDGQVLVRNHFLSLDPYMRGRMNDSKSYAQPQPLGEVMIGGTVGVVE
ASRNPAYAVGDNVVGMFGWQEVGISDGRGMQKVDTRHVPLSAYLGSVGMPGVTAWYGLNRIMHPKPGQTVAVSAASGAVG
SVVGQLAKLKGCRAVGFAGGKDKCDYVVNELGFDACIDYKAAKDPKELYAMLKEATPDGIDAYFENVGGDILDAVLRRMN
PFGRIAMCGMIAGYDGQPLPLQNPQLILVSRLTVEGFIVSEHMDVWPEALRELGGSVAQGKLKFRESVAQGLASAPEAFI
GLLKGKNFGKQLVKLV
>Mature_335_residues
SNTYQRIVLASRPEGAVTPDNFRLETAQIPELQDGQVLVRNHFLSLDPYMRGRMNDSKSYAQPQPLGEVMIGGTVGVVEA
SRNPAYAVGDNVVGMFGWQEVGISDGRGMQKVDTRHVPLSAYLGSVGMPGVTAWYGLNRIMHPKPGQTVAVSAASGAVGS
VVGQLAKLKGCRAVGFAGGKDKCDYVVNELGFDACIDYKAAKDPKELYAMLKEATPDGIDAYFENVGGDILDAVLRRMNP
FGRIAMCGMIAGYDGQPLPLQNPQLILVSRLTVEGFIVSEHMDVWPEALRELGGSVAQGKLKFRESVAQGLASAPEAFIG
LLKGKNFGKQLVKLV

Specific function: Putative quinone oxidoreductase that may contribute to the degradation of aromatic compounds (Potential) [H]

COG id: COG2130

COG function: function code R; Putative NADP-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADP-dependent oxidoreductase L4BD family [H]

Homologues:

Organism=Homo sapiens, GI226059159, Length=322, Percent_Identity=42.5465838509317, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI226059133, Length=322, Percent_Identity=42.5465838509317, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI226246682, Length=345, Percent_Identity=40, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI226246680, Length=345, Percent_Identity=40, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI22748929, Length=345, Percent_Identity=40, Blast_Score=226, Evalue=3e-59,
Organism=Homo sapiens, GI226056130, Length=281, Percent_Identity=42.7046263345196, Blast_Score=200, Evalue=2e-51,
Organism=Homo sapiens, GI28557745, Length=329, Percent_Identity=27.355623100304, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI226510941, Length=337, Percent_Identity=46.2908011869436, Blast_Score=291, Evalue=5e-80,
Organism=Caenorhabditis elegans, GI133901710, Length=351, Percent_Identity=35.042735042735, Blast_Score=184, Evalue=4e-47,
Organism=Caenorhabditis elegans, GI133901712, Length=351, Percent_Identity=35.042735042735, Blast_Score=184, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6323504, Length=324, Percent_Identity=29.6296296296296, Blast_Score=121, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00107 ADH_zinc_N [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36063; Mature: 35932

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTYQRIVLASRPEGAVTPDNFRLETAQIPELQDGQVLVRNHFLSLDPYMRGRMNDSKS
CCCCCEEEEEEECCCCCCCCCCCEEECCCCCCCCCCCEEEEHHCCCCCHHHHCCCCCCCC
YAQPQPLGEVMIGGTVGVVEASRNPAYAVGDNVVGMFGWQEVGISDGRGMQKVDTRHVPL
CCCCCCCCCEEECCEEEEEECCCCCCEEECCCEEEECCCCCCCCCCCCCCCHHCCCCCCH
SAYLGSVGMPGVTAWYGLNRIMHPKPGQTVAVSAASGAVGSVVGQLAKLKGCRAVGFAGG
HHHHCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEECCCCC
KDKCDYVVNELGFDACIDYKAAKDPKELYAMLKEATPDGIDAYFENVGGDILDAVLRRMN
CCHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCC
PFGRIAMCGMIAGYDGQPLPLQNPQLILVSRLTVEGFIVSEHMDVWPEALRELGGSVAQG
CCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEEEEEECHHHHHHHHHHHHCCHHHHH
KLKFRESVAQGLASAPEAFIGLLKGKNFGKQLVKLV
HHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHC
>Mature Secondary Structure 
SNTYQRIVLASRPEGAVTPDNFRLETAQIPELQDGQVLVRNHFLSLDPYMRGRMNDSKS
CCCCEEEEEEECCCCCCCCCCCEEECCCCCCCCCCCEEEEHHCCCCCHHHHCCCCCCCC
YAQPQPLGEVMIGGTVGVVEASRNPAYAVGDNVVGMFGWQEVGISDGRGMQKVDTRHVPL
CCCCCCCCCEEECCEEEEEECCCCCCEEECCCEEEECCCCCCCCCCCCCCCHHCCCCCCH
SAYLGSVGMPGVTAWYGLNRIMHPKPGQTVAVSAASGAVGSVVGQLAKLKGCRAVGFAGG
HHHHCCCCCCCHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCEECCCCC
KDKCDYVVNELGFDACIDYKAAKDPKELYAMLKEATPDGIDAYFENVGGDILDAVLRRMN
CCHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCHHHHHHHHHHCC
PFGRIAMCGMIAGYDGQPLPLQNPQLILVSRLTVEGFIVSEHMDVWPEALRELGGSVAQG
CCCHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEEEEEEEECHHHHHHHHHHHHCCHHHHH
KLKFRESVAQGLASAPEAFIGLLKGKNFGKQLVKLV
HHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9272861; 9384377 [H]