| Definition | Ralstonia solanacearum GMI1000, complete genome. |
|---|---|
| Accession | NC_003295 |
| Length | 3,716,413 |
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The map label for this gene is gno [H]
Identifier: 17546482
GI number: 17546482
Start: 1890411
End: 1891193
Strand: Direct
Name: gno [H]
Synonym: RSc1763
Alternate gene names: 17546482
Gene position: 1890411-1891193 (Clockwise)
Preceding gene: 17546481
Following gene: 17546483
Centisome position: 50.87
GC content: 67.56
Gene sequence:
>783_bases ATGGGCACGCTCAAGCATCTTTTCGACCTCTCCGGCAAGACCGCGCTGATCACCGGCGGCTCGCGCGGGCTGGGCCTGCA GATTGCCGAGGCCCTGGGCGAGCAGGGCGCGCGCATCGTGCTGTCGGCGCGCAAGGCCGATGAGCTGAAAGACGCGCAGG CGCATCTGCTGTCGCTGGGCATCGCGGCCGACTGGATCGCGGCGGACGGCGCGGTGGAGGCCGATATCCAGCGCCTGGCC GACGAGGCGCTCGCCAAGCTCGGTCATGTGGACATCCTCGTCAACAACGCCGGGGCGACCTGGGGCGCGCCGGCGGAGGA CCACCCGGTCGAAGCCTGGGACAAGGTGATGAACCTGAACATCCGCGGCCTGTTCCTGCTCACGCAGCAGATCGGCAAGC GCTCGATGATTCCGCGCCAATACGGCAAGATCGTCAACGTGGCGTCGATCGCCGGCCTGAAGGGCAACCCGCCGGGCACG CTCGATACCATCGCCTACAACACGAGCAAGGGCGCCGTGGTCAATTTCACGCGCGCGCTGGCGGGCGAGTGGGGCAAGTA CGGCATCACCGTCAATGCCATCGCCCCGGGCTTCTTCCCGTCCAAGATGACACGCGGCTCGCTGGAGAAGCTCGGCGTCG ACAAGCTGACCGAAAAATCCCCGCTGCACCGCCTCGGCGACGAGGAGGACCTCAAGGGCGTGGCCGCGCTGTTCGCTTCC GACGCCTCCAAGCACATCACCGGGCAGATCCTGGCGGTCGACGGCGGCGTGAGCGTGGTGTAA
Upstream 100 bases:
>100_bases TGGCCTCGCTCGACACCACCACGCTGGACATGCAGGACGCCTGGTTCTGAAGTTCTGGCGTTCCGACGTTCCATGGAACA CAACGACACAGGAGACACAC
Downstream 100 bases:
>100_bases TGCGGGCTGCCTGGCATTGAATCGGACGCAGCATGAATGCAGACAACCACGGTTTCCCGATCAACATTCCCTTCCTGCAA TGGCTGGGCGTGCGCTGCCT
Product: gluconate 5-dehydrogenase
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 260; Mature: 259
Protein sequence:
>260_residues MGTLKHLFDLSGKTALITGGSRGLGLQIAEALGEQGARIVLSARKADELKDAQAHLLSLGIAADWIAADGAVEADIQRLA DEALAKLGHVDILVNNAGATWGAPAEDHPVEAWDKVMNLNIRGLFLLTQQIGKRSMIPRQYGKIVNVASIAGLKGNPPGT LDTIAYNTSKGAVVNFTRALAGEWGKYGITVNAIAPGFFPSKMTRGSLEKLGVDKLTEKSPLHRLGDEEDLKGVAALFAS DASKHITGQILAVDGGVSVV
Sequences:
>Translated_260_residues MGTLKHLFDLSGKTALITGGSRGLGLQIAEALGEQGARIVLSARKADELKDAQAHLLSLGIAADWIAADGAVEADIQRLA DEALAKLGHVDILVNNAGATWGAPAEDHPVEAWDKVMNLNIRGLFLLTQQIGKRSMIPRQYGKIVNVASIAGLKGNPPGT LDTIAYNTSKGAVVNFTRALAGEWGKYGITVNAIAPGFFPSKMTRGSLEKLGVDKLTEKSPLHRLGDEEDLKGVAALFAS DASKHITGQILAVDGGVSVV >Mature_259_residues GTLKHLFDLSGKTALITGGSRGLGLQIAEALGEQGARIVLSARKADELKDAQAHLLSLGIAADWIAADGAVEADIQRLAD EALAKLGHVDILVNNAGATWGAPAEDHPVEAWDKVMNLNIRGLFLLTQQIGKRSMIPRQYGKIVNVASIAGLKGNPPGTL DTIAYNTSKGAVVNFTRALAGEWGKYGITVNAIAPGFFPSKMTRGSLEKLGVDKLTEKSPLHRLGDEEDLKGVAALFASD ASKHITGQILAVDGGVSVV
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: NA
COG function: NA
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Unknown [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI40254992, Length=248, Percent_Identity=35.8870967741936, Blast_Score=121, Evalue=8e-28, Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=31.7269076305221, Blast_Score=118, Evalue=6e-27, Organism=Homo sapiens, GI19923817, Length=258, Percent_Identity=31.7829457364341, Blast_Score=112, Evalue=3e-25, Organism=Homo sapiens, GI5031737, Length=255, Percent_Identity=31.3725490196078, Blast_Score=105, Evalue=5e-23, Organism=Homo sapiens, GI10190704, Length=262, Percent_Identity=31.6793893129771, Blast_Score=104, Evalue=7e-23, Organism=Homo sapiens, GI15277342, Length=145, Percent_Identity=39.3103448275862, Blast_Score=103, Evalue=1e-22, Organism=Homo sapiens, GI4503301, Length=258, Percent_Identity=31.0077519379845, Blast_Score=98, Evalue=7e-21, Organism=Homo sapiens, GI126723750, Length=253, Percent_Identity=28.4584980237154, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI4758504, Length=265, Percent_Identity=30.188679245283, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI210032110, Length=206, Percent_Identity=30.5825242718447, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI33667109, Length=202, Percent_Identity=31.1881188118812, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI66933014, Length=256, Percent_Identity=26.953125, Blast_Score=86, Evalue=2e-17, Organism=Homo sapiens, GI7705925, Length=256, Percent_Identity=29.296875, Blast_Score=86, Evalue=3e-17, Organism=Homo sapiens, GI7706318, Length=211, Percent_Identity=32.2274881516588, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI20149619, Length=201, Percent_Identity=31.3432835820896, Blast_Score=80, Evalue=3e-15, Organism=Homo sapiens, GI209862901, Length=212, Percent_Identity=26.4150943396226, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI19923983, Length=212, Percent_Identity=26.4150943396226, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI126723191, Length=186, Percent_Identity=31.1827956989247, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI4503817, Length=192, Percent_Identity=31.25, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI7705855, Length=209, Percent_Identity=30.1435406698565, Blast_Score=76, Evalue=3e-14, Organism=Homo sapiens, GI157739938, Length=197, Percent_Identity=29.9492385786802, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI59889578, Length=235, Percent_Identity=27.2340425531915, Blast_Score=75, Evalue=5e-14, Organism=Homo sapiens, GI40254986, Length=206, Percent_Identity=34.9514563106796, Blast_Score=75, Evalue=7e-14, Organism=Homo sapiens, GI226371731, Length=214, Percent_Identity=29.4392523364486, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI83715985, Length=266, Percent_Identity=28.5714285714286, Blast_Score=73, Evalue=3e-13, Organism=Homo sapiens, GI31542939, Length=217, Percent_Identity=30.8755760368664, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI31543615, Length=202, Percent_Identity=32.1782178217822, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI142976729, Length=210, Percent_Identity=28.0952380952381, Blast_Score=66, Evalue=4e-11, Organism=Homo sapiens, GI109715829, Length=197, Percent_Identity=28.4263959390863, Blast_Score=66, Evalue=4e-11, Organism=Escherichia coli, GI1790717, Length=258, Percent_Identity=34.4961240310078, Blast_Score=145, Evalue=2e-36, Organism=Escherichia coli, GI87082160, Length=257, Percent_Identity=33.852140077821, Blast_Score=140, Evalue=1e-34, Organism=Escherichia coli, GI1789208, Length=259, Percent_Identity=35.9073359073359, Blast_Score=135, Evalue=2e-33, Organism=Escherichia coli, GI1787335, Length=253, Percent_Identity=33.201581027668, Blast_Score=131, Evalue=5e-32, Organism=Escherichia coli, GI87082100, Length=254, Percent_Identity=34.251968503937, Blast_Score=113, Evalue=2e-26, Organism=Escherichia coli, GI1788459, Length=253, Percent_Identity=32.8063241106719, Blast_Score=110, Evalue=1e-25, Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=33.1983805668016, Blast_Score=108, Evalue=4e-25, Organism=Escherichia coli, GI2367175, Length=252, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=3e-20, Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=27.8884462151394, Blast_Score=87, Evalue=8e-19, Organism=Escherichia coli, GI1789057, Length=262, Percent_Identity=25.9541984732824, Blast_Score=78, Evalue=7e-16, Organism=Escherichia coli, GI1786812, Length=268, Percent_Identity=26.865671641791, Blast_Score=70, Evalue=1e-13, Organism=Escherichia coli, GI1787820, Length=185, Percent_Identity=29.1891891891892, Blast_Score=68, Evalue=5e-13, Organism=Escherichia coli, GI2367365, Length=246, Percent_Identity=28.8617886178862, Blast_Score=67, Evalue=1e-12, Organism=Escherichia coli, GI1786701, Length=236, Percent_Identity=29.2372881355932, Blast_Score=64, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17562906, Length=272, Percent_Identity=32.7205882352941, Blast_Score=129, Evalue=2e-30, Organism=Caenorhabditis elegans, GI17562908, Length=270, Percent_Identity=32.2222222222222, Blast_Score=125, Evalue=3e-29, Organism=Caenorhabditis elegans, GI193204405, Length=271, Percent_Identity=33.5793357933579, Blast_Score=120, Evalue=9e-28, Organism=Caenorhabditis elegans, GI17560220, Length=271, Percent_Identity=33.210332103321, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI17531453, Length=268, Percent_Identity=32.8358208955224, Blast_Score=117, Evalue=6e-27, Organism=Caenorhabditis elegans, GI17561402, Length=259, Percent_Identity=34.7490347490347, Blast_Score=117, Evalue=6e-27, Organism=Caenorhabditis elegans, GI17560150, Length=268, Percent_Identity=31.7164179104478, Blast_Score=117, Evalue=7e-27, Organism=Caenorhabditis elegans, GI17562990, Length=271, Percent_Identity=31.7343173431734, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17555706, Length=248, Percent_Identity=32.258064516129, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17559104, Length=267, Percent_Identity=30.3370786516854, Blast_Score=114, Evalue=5e-26, Organism=Caenorhabditis elegans, GI71994600, Length=258, Percent_Identity=33.7209302325581, Blast_Score=112, Evalue=1e-25, Organism=Caenorhabditis elegans, GI25147288, Length=258, Percent_Identity=31.7829457364341, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI17538480, Length=274, Percent_Identity=32.1167883211679, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17562904, Length=270, Percent_Identity=28.1481481481481, Blast_Score=109, Evalue=2e-24, Organism=Caenorhabditis elegans, GI71994604, Length=257, Percent_Identity=31.9066147859922, Blast_Score=108, Evalue=2e-24, Organism=Caenorhabditis elegans, GI17560332, Length=270, Percent_Identity=30, Blast_Score=106, Evalue=1e-23, Organism=Caenorhabditis elegans, GI17551412, Length=270, Percent_Identity=30.3703703703704, Blast_Score=105, Evalue=2e-23, Organism=Caenorhabditis elegans, GI17536025, Length=256, Percent_Identity=29.296875, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17565030, Length=268, Percent_Identity=30.2238805970149, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17561272, Length=254, Percent_Identity=31.496062992126, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=29.2134831460674, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17536651, Length=253, Percent_Identity=28.0632411067194, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17560676, Length=255, Percent_Identity=27.843137254902, Blast_Score=96, Evalue=2e-20, Organism=Caenorhabditis elegans, GI17538486, Length=270, Percent_Identity=28.1481481481481, Blast_Score=95, Evalue=4e-20, Organism=Caenorhabditis elegans, GI115534694, Length=268, Percent_Identity=30.9701492537313, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17544670, Length=267, Percent_Identity=28.4644194756554, Blast_Score=93, Evalue=1e-19, Organism=Caenorhabditis elegans, GI72000259, Length=274, Percent_Identity=27.7372262773723, Blast_Score=91, Evalue=7e-19, Organism=Caenorhabditis elegans, GI17563726, Length=270, Percent_Identity=27.4074074074074, Blast_Score=91, Evalue=8e-19, Organism=Caenorhabditis elegans, GI193203115, Length=200, Percent_Identity=33.5, Blast_Score=86, Evalue=3e-17, Organism=Caenorhabditis elegans, GI193203117, Length=202, Percent_Identity=33.1683168316832, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17564282, Length=205, Percent_Identity=28.780487804878, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI71982365, Length=199, Percent_Identity=31.1557788944724, Blast_Score=79, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17555612, Length=206, Percent_Identity=33.9805825242718, Blast_Score=77, Evalue=7e-15, Organism=Caenorhabditis elegans, GI71997099, Length=206, Percent_Identity=29.126213592233, Blast_Score=73, Evalue=1e-13, Organism=Caenorhabditis elegans, GI17558006, Length=222, Percent_Identity=28.3783783783784, Blast_Score=70, Evalue=8e-13, Organism=Caenorhabditis elegans, GI17568967, Length=193, Percent_Identity=25.3886010362694, Blast_Score=67, Evalue=7e-12, Organism=Caenorhabditis elegans, GI17558628, Length=201, Percent_Identity=31.3432835820896, Blast_Score=67, Evalue=8e-12, Organism=Caenorhabditis elegans, GI17508895, Length=207, Percent_Identity=28.0193236714976, Blast_Score=64, Evalue=6e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=225, Percent_Identity=29.3333333333333, Blast_Score=66, Evalue=5e-12, Organism=Saccharomyces cerevisiae, GI6324126, Length=257, Percent_Identity=25.2918287937743, Blast_Score=65, Evalue=1e-11, Organism=Drosophila melanogaster, GI24644339, Length=255, Percent_Identity=35.6862745098039, Blast_Score=131, Evalue=5e-31, Organism=Drosophila melanogaster, GI21357041, Length=250, Percent_Identity=35.6, Blast_Score=130, Evalue=7e-31, Organism=Drosophila melanogaster, GI28571526, Length=250, Percent_Identity=35.6, Blast_Score=129, Evalue=2e-30, Organism=Drosophila melanogaster, GI23397609, Length=254, Percent_Identity=32.2834645669291, Blast_Score=120, Evalue=9e-28, Organism=Drosophila melanogaster, GI21355319, Length=266, Percent_Identity=31.203007518797, Blast_Score=119, Evalue=1e-27, Organism=Drosophila melanogaster, GI24639444, Length=252, Percent_Identity=32.9365079365079, Blast_Score=111, Evalue=6e-25, Organism=Drosophila melanogaster, GI24644337, Length=259, Percent_Identity=31.2741312741313, Blast_Score=100, Evalue=7e-22, Organism=Drosophila melanogaster, GI21358495, Length=219, Percent_Identity=31.5068493150685, Blast_Score=89, Evalue=4e-18, Organism=Drosophila melanogaster, GI24643142, Length=267, Percent_Identity=29.2134831460674, Blast_Score=87, Evalue=8e-18, Organism=Drosophila melanogaster, GI17737361, Length=264, Percent_Identity=29.1666666666667, Blast_Score=82, Evalue=4e-16, Organism=Drosophila melanogaster, GI24584744, Length=203, Percent_Identity=31.5270935960591, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI28574402, Length=203, Percent_Identity=31.5270935960591, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI161076933, Length=206, Percent_Identity=30.5825242718447, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI24584748, Length=206, Percent_Identity=31.0679611650485, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI21357673, Length=194, Percent_Identity=28.8659793814433, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24641232, Length=246, Percent_Identity=28.4552845528455, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI18859837, Length=214, Percent_Identity=26.6355140186916, Blast_Score=69, Evalue=4e-12, Organism=Drosophila melanogaster, GI161076371, Length=222, Percent_Identity=27.4774774774775, Blast_Score=64, Evalue=7e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 27264; Mature: 27132
Theoretical pI: Translated: 7.19; Mature: 7.19
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.0 %Cys (Translated Protein) 1.5 %Met (Translated Protein) 1.5 %Cys+Met (Translated Protein) 0.0 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 1.2 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MGTLKHLFDLSGKTALITGGSRGLGLQIAEALGEQGARIVLSARKADELKDAQAHLLSLG CCCHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHH IAADWIAADGAVEADIQRLADEALAKLGHVDILVNNAGATWGAPAEDHPVEAWDKVMNLN HHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCC IRGLFLLTQQIGKRSMIPRQYGKIVNVASIAGLKGNPPGTLDTIAYNTSKGAVVNFTRAL CHHHHHHHHHHCCCCCCHHHHHHHEEHHHHCCCCCCCCCCEEEEEEECCCCCEEEHHHHH AGEWGKYGITVNAIAPGFFPSKMTRGSLEKLGVDKLTEKSPLHRLGDEEDLKGVAALFAS HCCCCCCCEEEEEECCCCCCHHHCCCHHHHCCCHHHHCCCHHHHCCCHHHHHHHHHHHHC DASKHITGQILAVDGGVSVV CCCCCCEEEEEEECCCCCCC >Mature Secondary Structure GTLKHLFDLSGKTALITGGSRGLGLQIAEALGEQGARIVLSARKADELKDAQAHLLSLG CCHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHH IAADWIAADGAVEADIQRLADEALAKLGHVDILVNNAGATWGAPAEDHPVEAWDKVMNLN HHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHCCC IRGLFLLTQQIGKRSMIPRQYGKIVNVASIAGLKGNPPGTLDTIAYNTSKGAVVNFTRAL CHHHHHHHHHHCCCCCCHHHHHHHEEHHHHCCCCCCCCCCEEEEEEECCCCCEEEHHHHH AGEWGKYGITVNAIAPGFFPSKMTRGSLEKLGVDKLTEKSPLHRLGDEEDLKGVAALFAS HCCCCCCCEEEEEECCCCCCHHHCCCHHHHCCCHHHHCCCHHHHCCCHHHHHHHHHHHHC DASKHITGQILAVDGGVSVV CCCCCCEEEEEEECCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]