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The map label for this gene is aidB [H]

Identifier: 17546481

GI number: 17546481

Start: 1888483

End: 1890360

Strand: Direct

Name: aidB [H]

Synonym: RSc1762

Alternate gene names: 17546481

Gene position: 1888483-1890360 (Clockwise)

Preceding gene: 17546480

Following gene: 17546482

Centisome position: 50.81

GC content: 69.01

Gene sequence:

>1878_bases
ATGTCCTCTCTGCTGCTGTCGCGCCGCGACCTGAGCTTTGTGCTCTACGAATGGCTCGACGTGGAGGCGCTTACGCGCTT
TCCGCGTTATGCCGACCACTCCCGCGAAACCTTCGATGCGGCGCTCGATACCTGCGAGCGCATCGCCACCGACCTGTTCG
CGCCGCACAACAAGAAGAACGACCAGCAGGAGCCGCATTTCGACGGCACCGCGGTCCACATCATTCCCGAGGTGAAGACG
GCGCTGGACGCCTTCAACAAGGCGGGCCTGATGGCCGCGGGGCAGGATTTCGAGCGCGGCGGCATGCAACTGCCCACCGT
GGTCGAGAAGGCCGGCTTCGGTTTCTTCAAGGCGGCCAATGTCGGCACCAGTTCCTATCCGTTCCTGACCATCGGCAATG
CCAACCTGCTGCTGGCGCACGGCACGCCCGCGCAGATCGAGACGTTCGTGCAGCCCGAGCTGGAGGGGCGCTTCTACGGC
ACGATGTGCCTGTCGGAGCCGCAGGCGGGGTCGTCGCTGTCGGACATCGCCACGCGCGCCGAATACGAGGGCGAATCGCC
GCTGGGGCCGCAGTACCGGCTGACCGGCAACAAGATGTGGATCTCGGCCGGCGAGCACGCGCTGTCGGACAACATCGTGC
ATCTGGTGCTGGCCAAGATTCCCGGCCCGGACGGCAAGCCGATCCCCGGCGTGAAGGGCATCTCGCTGTTCATCGTGCCC
AAGTTCCTTGTCGGCGCGGACGGGGCGCTGGGCGAGCGCAACGACGTGGCGCTCGCCGGGCTGAACCACAAGATGGGCTA
CCGCGGCACCACCAACTGCCTGCTCAACTTCGGCGAAGGCACGCAGTTCCGCCCCAAGGGGCCGGACGGCCAGCCGCGCG
CCGGCGCCATCGGCTACCTGGTCGGCGAGCCGCACCAGGGGCTGGCGTGCATGTTCCACATGATGAACGAGGCGCGCATC
GGTGTCGGCATGGGGGCGACCATGCTGGGCTACACCGGCTACCTGCACGCGCTGGACTACGCGCGCAATCGCCCGCAGGG
CCGGCCGATCGGCCCGGCCGGCAAGGATGCCGCGTCGCCGCAGGTCCGTATCGTCGACCACGCCGACGTGCGCCGCATGC
TGCTGGCGCAGAAGGCCTACGTGGAAGGCGCGCTCGGTCTGAACCTGTATTGCGCCAAGCTGGTCGACGAGGAGCGCGGC
GCGGAAAGCGAGGGCGACGCCGACGCGCGCGCCACGCTCGGCCTGCTGCTCGACATCCTCACGCCGATCGCCAAGAGCTG
GCCGTCGCAGTGGTGCCTGGAGGCCAACAGCCTGGCGATCCAGGTGCATGGCGGCTACGGCTACACGCGCGAGTACAACG
TCGAGCAGTTCTATCGCGACAACCGCCTGAACCCGATCCACGAAGGCACGCACGGCATCCAGGGGCTGGACCTGCTCGGT
CGCAAGGTGGTGATGCAGGACGGCGCCGCCTTCGCCGCGCTGGGCCGGCGCGTGCAGGCCACCGTGGCCCGCGCGCTGGA
CAGCGGCGATGCGGCGCTGGCCGGCTGGGGCCGCGCGCTCGGCATGGCTGCCCAGAGCCTGGCCAAGGTGACGCAGCAGT
TGTGGGCGGCGGGCGATCCGCGCGTGACGCTGGCCAATGCCTCGGTCTACCTGGAGGCGTTCGGCCACGTCGTCATCGCG
TGGATCTGGCTGGAGCAGGCGCTCGCCGCCGCGCGGGCCCTGCCTGGCGCCCAGGGCGACGATGCCGGCTTCTATCGCGG
CAAGCTGCAGGCCGCGCGCTATTTCTTCCAGTGGGAGCTGCCGAAGACCGGTCCGCAGCTGGCGCTGCTGGCCTCGCTCG
ACACCACCACGCTGGACATGCAGGACGCCTGGTTCTGA

Upstream 100 bases:

>100_bases
CGCCGCGCGGGAGCCCGCTTCGCTTCGTCGCCCCGTGCGCGGCCGCTCGGCGCAGGGGCGGCATGGATCGCCTGTCCGGA
ACCCACCCTCCCGCATCGTC

Downstream 100 bases:

>100_bases
AGTTCTGGCGTTCCGACGTTCCATGGAACACAACGACACAGGAGACACACATGGGCACGCTCAAGCATCTTTTCGACCTC
TCCGGCAAGACCGCGCTGAT

Product: acyl-CoA dehydrogenase oxidoreductase

Products: 2-butenoyl-CoA; reduced acceptor

Alternate protein names: NA

Number of amino acids: Translated: 625; Mature: 624

Protein sequence:

>625_residues
MSSLLLSRRDLSFVLYEWLDVEALTRFPRYADHSRETFDAALDTCERIATDLFAPHNKKNDQQEPHFDGTAVHIIPEVKT
ALDAFNKAGLMAAGQDFERGGMQLPTVVEKAGFGFFKAANVGTSSYPFLTIGNANLLLAHGTPAQIETFVQPELEGRFYG
TMCLSEPQAGSSLSDIATRAEYEGESPLGPQYRLTGNKMWISAGEHALSDNIVHLVLAKIPGPDGKPIPGVKGISLFIVP
KFLVGADGALGERNDVALAGLNHKMGYRGTTNCLLNFGEGTQFRPKGPDGQPRAGAIGYLVGEPHQGLACMFHMMNEARI
GVGMGATMLGYTGYLHALDYARNRPQGRPIGPAGKDAASPQVRIVDHADVRRMLLAQKAYVEGALGLNLYCAKLVDEERG
AESEGDADARATLGLLLDILTPIAKSWPSQWCLEANSLAIQVHGGYGYTREYNVEQFYRDNRLNPIHEGTHGIQGLDLLG
RKVVMQDGAAFAALGRRVQATVARALDSGDAALAGWGRALGMAAQSLAKVTQQLWAAGDPRVTLANASVYLEAFGHVVIA
WIWLEQALAAARALPGAQGDDAGFYRGKLQAARYFFQWELPKTGPQLALLASLDTTTLDMQDAWF

Sequences:

>Translated_625_residues
MSSLLLSRRDLSFVLYEWLDVEALTRFPRYADHSRETFDAALDTCERIATDLFAPHNKKNDQQEPHFDGTAVHIIPEVKT
ALDAFNKAGLMAAGQDFERGGMQLPTVVEKAGFGFFKAANVGTSSYPFLTIGNANLLLAHGTPAQIETFVQPELEGRFYG
TMCLSEPQAGSSLSDIATRAEYEGESPLGPQYRLTGNKMWISAGEHALSDNIVHLVLAKIPGPDGKPIPGVKGISLFIVP
KFLVGADGALGERNDVALAGLNHKMGYRGTTNCLLNFGEGTQFRPKGPDGQPRAGAIGYLVGEPHQGLACMFHMMNEARI
GVGMGATMLGYTGYLHALDYARNRPQGRPIGPAGKDAASPQVRIVDHADVRRMLLAQKAYVEGALGLNLYCAKLVDEERG
AESEGDADARATLGLLLDILTPIAKSWPSQWCLEANSLAIQVHGGYGYTREYNVEQFYRDNRLNPIHEGTHGIQGLDLLG
RKVVMQDGAAFAALGRRVQATVARALDSGDAALAGWGRALGMAAQSLAKVTQQLWAAGDPRVTLANASVYLEAFGHVVIA
WIWLEQALAAARALPGAQGDDAGFYRGKLQAARYFFQWELPKTGPQLALLASLDTTTLDMQDAWF
>Mature_624_residues
SSLLLSRRDLSFVLYEWLDVEALTRFPRYADHSRETFDAALDTCERIATDLFAPHNKKNDQQEPHFDGTAVHIIPEVKTA
LDAFNKAGLMAAGQDFERGGMQLPTVVEKAGFGFFKAANVGTSSYPFLTIGNANLLLAHGTPAQIETFVQPELEGRFYGT
MCLSEPQAGSSLSDIATRAEYEGESPLGPQYRLTGNKMWISAGEHALSDNIVHLVLAKIPGPDGKPIPGVKGISLFIVPK
FLVGADGALGERNDVALAGLNHKMGYRGTTNCLLNFGEGTQFRPKGPDGQPRAGAIGYLVGEPHQGLACMFHMMNEARIG
VGMGATMLGYTGYLHALDYARNRPQGRPIGPAGKDAASPQVRIVDHADVRRMLLAQKAYVEGALGLNLYCAKLVDEERGA
ESEGDADARATLGLLLDILTPIAKSWPSQWCLEANSLAIQVHGGYGYTREYNVEQFYRDNRLNPIHEGTHGIQGLDLLGR
KVVMQDGAAFAALGRRVQATVARALDSGDAALAGWGRALGMAAQSLAKVTQQLWAAGDPRVTLANASVYLEAFGHVVIAW
IWLEQALAAARALPGAQGDDAGFYRGKLQAARYFFQWELPKTGPQLALLASLDTTTLDMQDAWF

Specific function: May help to prevent alkylation damage by protecting DNA and destroying alkylating agents [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=415, Percent_Identity=26.9879518072289, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI7656849, Length=406, Percent_Identity=26.1083743842365, Blast_Score=84, Evalue=4e-16,
Organism=Homo sapiens, GI4501857, Length=349, Percent_Identity=26.0744985673352, Blast_Score=81, Evalue=3e-15,
Organism=Homo sapiens, GI226958414, Length=347, Percent_Identity=25.9365994236311, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI226958412, Length=347, Percent_Identity=25.9365994236311, Blast_Score=77, Evalue=6e-14,
Organism=Escherichia coli, GI87082384, Length=439, Percent_Identity=25.0569476082005, Blast_Score=82, Evalue=1e-16,
Organism=Drosophila melanogaster, GI21356377, Length=450, Percent_Identity=26.8888888888889, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24646207, Length=443, Percent_Identity=25.2821670428894, Blast_Score=84, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M [H]

EC number: 1.3.99.2

Molecular weight: Translated: 67572; Mature: 67440

Theoretical pI: Translated: 6.21; Mature: 6.21

Prosite motif: PS00216 SUGAR_TRANSPORT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLLLSRRDLSFVLYEWLDVEALTRFPRYADHSRETFDAALDTCERIATDLFAPHNKKN
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
DQQEPHFDGTAVHIIPEVKTALDAFNKAGLMAAGQDFERGGMQLPTVVEKAGFGFFKAAN
CCCCCCCCCEEEEEEHHHHHHHHHHHHCCCEECCCCHHCCCCCCCHHHHHCCCCEEEECC
VGTSSYPFLTIGNANLLLAHGTPAQIETFVQPELEGRFYGTMCLSEPQAGSSLSDIATRA
CCCCCCCEEEECCCEEEEECCCCHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHH
EYEGESPLGPQYRLTGNKMWISAGEHALSDNIVHLVLAKIPGPDGKPIPGVKGISLFIVP
HCCCCCCCCCCEEECCCEEEEECCCHHHHCCEEEEEEEECCCCCCCCCCCCCCEEEEEEE
KFLVGADGALGERNDVALAGLNHKMGYRGTTNCLLNFGEGTQFRPKGPDGQPRAGAIGYL
HHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEE
VGEPHQGLACMFHMMNEARIGVGMGATMLGYTGYLHALDYARNRPQGRPIGPAGKDAASP
ECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
QVRIVDHADVRRMLLAQKAYVEGALGLNLYCAKLVDEERGAESEGDADARATLGLLLDIL
CEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
TPIAKSWPSQWCLEANSLAIQVHGGYGYTREYNVEQFYRDNRLNPIHEGTHGIQGLDLLG
HHHHHCCCHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHC
RKVVMQDGAAFAALGRRVQATVARALDSGDAALAGWGRALGMAAQSLAKVTQQLWAAGDP
CHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RVTLANASVYLEAFGHVVIAWIWLEQALAAARALPGAQGDDAGFYRGKLQAARYFFQWEL
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHEEEEEEEEEC
PKTGPQLALLASLDTTTLDMQDAWF
CCCCCCEEEEEECCCCEECCCCCCC
>Mature Secondary Structure 
SSLLLSRRDLSFVLYEWLDVEALTRFPRYADHSRETFDAALDTCERIATDLFAPHNKKN
CCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCC
DQQEPHFDGTAVHIIPEVKTALDAFNKAGLMAAGQDFERGGMQLPTVVEKAGFGFFKAAN
CCCCCCCCCEEEEEEHHHHHHHHHHHHCCCEECCCCHHCCCCCCCHHHHHCCCCEEEECC
VGTSSYPFLTIGNANLLLAHGTPAQIETFVQPELEGRFYGTMCLSEPQAGSSLSDIATRA
CCCCCCCEEEECCCEEEEECCCCHHHHHHCCCCCCCEEEEEEEECCCCCCCCHHHHHHHH
EYEGESPLGPQYRLTGNKMWISAGEHALSDNIVHLVLAKIPGPDGKPIPGVKGISLFIVP
HCCCCCCCCCCEEECCCEEEEECCCHHHHCCEEEEEEEECCCCCCCCCCCCCCEEEEEEE
KFLVGADGALGERNDVALAGLNHKMGYRGTTNCLLNFGEGTQFRPKGPDGQPRAGAIGYL
HHHHCCCCCCCCCCCEEEEECCCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCEEEEE
VGEPHQGLACMFHMMNEARIGVGMGATMLGYTGYLHALDYARNRPQGRPIGPAGKDAASP
ECCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
QVRIVDHADVRRMLLAQKAYVEGALGLNLYCAKLVDEERGAESEGDADARATLGLLLDIL
CEEEECHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
TPIAKSWPSQWCLEANSLAIQVHGGYGYTREYNVEQFYRDNRLNPIHEGTHGIQGLDLLG
HHHHHCCCHHHCCCCCCEEEEEECCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCHHHHC
RKVVMQDGAAFAALGRRVQATVARALDSGDAALAGWGRALGMAAQSLAKVTQQLWAAGDP
CHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RVTLANASVYLEAFGHVVIAWIWLEQALAAARALPGAQGDDAGFYRGKLQAARYFFQWEL
CEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHEEEEEEEEEC
PKTGPQLALLASLDTTTLDMQDAWF
CCCCCCEEEEEECCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: butanoyl-CoA; acceptor

Specific reaction: butanoyl-CoA + acceptor = 2-butenoyl-CoA + reduced acceptor

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7961409; 7610040; 9278503 [H]