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The map label for this gene is clpX [H]

Identifier: 17546431

GI number: 17546431

Start: 1829064

End: 1830338

Strand: Direct

Name: clpX [H]

Synonym: RSc1712

Alternate gene names: 17546431

Gene position: 1829064-1830338 (Clockwise)

Preceding gene: 17546430

Following gene: 17546432

Centisome position: 49.22

GC content: 60.16

Gene sequence:

>1275_bases
ATGGCGGACAAGAAAGGCTCGACTGGCGAAAAGCTGCTGTACTGCTCGTTCTGCGGCAAGAGCCAGCATGAAGTCAAGAA
ACTGATTGCCGGCCCCTCGGTCTTCATCTGCGATGAATGTATCGACCTGTGCAATGAAATCATCCGGGACGAGGCCGCGA
TCTCCGAGAAGGAGGGCGGGCTGGCGGTCAAATCCGACCTGCCGACCCCGCACGAGATTCGCCAGAGCCTGGATCAATAC
GTGATCGGCCAGGAGCAGGCCAAGAAGATCCTGGCGGTTGCGGTCTATAACCATTACAAGCGCTTGAAGCATCTCGGCAA
GAAGGATGATGTCGAGCTGTCCAAGAGCAACATCCTGCTCATCGGGCCGACCGGCTCGGGCAAGACGCTGCTGGCGCAGA
CGCTGGCTCGCTTGCTGAACGTGCCGTTCGTCATCGCCGACGCCACCACGCTGACCGAAGCCGGCTACGTGGGCGAGGAC
GTCGAGAACATCATCCAGAAGCTGCTGCAGAACTGCAATTACGAGGTCGACAAGGCACAGCGTGGCATTGTCTACATCGA
TGAGATCGACAAGATTTCGCGCAAGTCCGACAACCCGTCCATCACCCGCGACGTTTCCGGGGAAGGCGTGCAGCAGGCCC
TGCTGAAGCTGATTGAAGGGACGATGGCCTCGGTGCCGCCGCAGGGCGGGCGCAAGCACCCGAACCAGGATTTCCTCCAG
GTCGACACTACCAATATCCTGTTTATCTGCGGCGGTGCGTTCGATGGTCTCGAGAAGATCATCACGCAGCGCTCGGACAA
GTCCGGCATCGGCTTCGGCGCCGAGGTCAAGAGCAAGGAAGAGCGGGACGTCAACGAAGTGCTGCCGCAGGTAGAGCCGG
AAGACCTGATCAAGTTCGGCCTGATTCCCGAACTGATCGGCCGCCTGCCCGTGGTGGCGACGCTGGCCAAGCTGGACGAG
GCCGCGCTGATGGAGATCCTGGTCGAGCCGAAGAATGCAATCGTCAAGCAGTATCAAAAACTGCTGGCCATGGAAGGGGT
GGAGCTGGAAATCCGTCCGAGCGCGCTGACGGCGATTGCCCGCAAGGCGATCAAGCGCAAGACGGGGGCGCGCGGATTGC
GCTCCATCGTCGAGCACGCGCTGATGGATGTGATGTACGACCTTCCCAACCACAAGGGTGTGCAGAAGGTGGTGATCGAC
GAGAGCACGATCGCCGGCGACGGCAAGCCCTTGCTGATGTACGAAGAGCAACCCAAGGTTGCAGGTTCCAACTGA

Upstream 100 bases:

>100_bases
AAGACGAGGCCTCGCGCCTCGTTTTTGCTATGTGCAACACCTGCGGATCGTCGCCAGGCAATTTGGCGTATGATGCGGTC
AGGAACTACTGGTTATCGTT

Downstream 100 bases:

>100_bases
CGCGAATGACTGGCCGGGATGCGCCGTATGCATCCCATGCAGGAAGCCGTTCGCACGCGAGCGGCTTTTTTTGCTTCGGG
AAACCGGGCCGGCACGCGAC

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 423

Protein sequence:

>424_residues
MADKKGSTGEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAISEKEGGLAVKSDLPTPHEIRQSLDQY
VIGQEQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGED
VENIIQKLLQNCNYEVDKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
VDTTNILFICGGAFDGLEKIITQRSDKSGIGFGAEVKSKEERDVNEVLPQVEPEDLIKFGLIPELIGRLPVVATLAKLDE
AALMEILVEPKNAIVKQYQKLLAMEGVELEIRPSALTAIARKAIKRKTGARGLRSIVEHALMDVMYDLPNHKGVQKVVID
ESTIAGDGKPLLMYEEQPKVAGSN

Sequences:

>Translated_424_residues
MADKKGSTGEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAISEKEGGLAVKSDLPTPHEIRQSLDQY
VIGQEQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGED
VENIIQKLLQNCNYEVDKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
VDTTNILFICGGAFDGLEKIITQRSDKSGIGFGAEVKSKEERDVNEVLPQVEPEDLIKFGLIPELIGRLPVVATLAKLDE
AALMEILVEPKNAIVKQYQKLLAMEGVELEIRPSALTAIARKAIKRKTGARGLRSIVEHALMDVMYDLPNHKGVQKVVID
ESTIAGDGKPLLMYEEQPKVAGSN
>Mature_423_residues
ADKKGSTGEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAISEKEGGLAVKSDLPTPHEIRQSLDQYV
IGQEQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILLIGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDV
ENIIQKLLQNCNYEVDKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQV
DTTNILFICGGAFDGLEKIITQRSDKSGIGFGAEVKSKEERDVNEVLPQVEPEDLIKFGLIPELIGRLPVVATLAKLDEA
ALMEILVEPKNAIVKQYQKLLAMEGVELEIRPSALTAIARKAIKRKTGARGLRSIVEHALMDVMYDLPNHKGVQKVVIDE
STIAGDGKPLLMYEEQPKVAGSN

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=326, Percent_Identity=51.5337423312883, Blast_Score=315, Evalue=4e-86,
Organism=Escherichia coli, GI1786642, Length=418, Percent_Identity=73.9234449760766, Blast_Score=615, Evalue=1e-177,
Organism=Escherichia coli, GI1790366, Length=100, Percent_Identity=47, Blast_Score=99, Evalue=4e-22,
Organism=Caenorhabditis elegans, GI71988663, Length=401, Percent_Identity=41.8952618453865, Blast_Score=283, Evalue=1e-76,
Organism=Caenorhabditis elegans, GI71982908, Length=314, Percent_Identity=44.5859872611465, Blast_Score=266, Evalue=1e-71,
Organism=Caenorhabditis elegans, GI71982905, Length=314, Percent_Identity=44.5859872611465, Blast_Score=266, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI71988660, Length=261, Percent_Identity=42.911877394636, Blast_Score=191, Evalue=6e-49,
Organism=Saccharomyces cerevisiae, GI6319704, Length=426, Percent_Identity=40.1408450704225, Blast_Score=277, Evalue=2e-75,
Organism=Drosophila melanogaster, GI24648291, Length=320, Percent_Identity=46.25, Blast_Score=284, Evalue=1e-76,
Organism=Drosophila melanogaster, GI24648289, Length=320, Percent_Identity=46.25, Blast_Score=284, Evalue=1e-76,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46404; Mature: 46273

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADKKGSTGEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAISEKEGG
CCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCC
LAVKSDLPTPHEIRQSLDQYVIGQEQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILL
EEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEE
IGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVDKAQ
EECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCEEHHHC
RGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
CCEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
VDTTNILFICGGAFDGLEKIITQRSDKSGIGFGAEVKSKEERDVNEVLPQVEPEDLIKFG
EECCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCHHHHCCCCCHHHHHHHC
LIPELIGRLPVVATLAKLDEAALMEILVEPKNAIVKQYQKLLAMEGVELEIRPSALTAIA
CHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHH
RKAIKRKTGARGLRSIVEHALMDVMYDLPNHKGVQKVVIDESTIAGDGKPLLMYEEQPKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEECCCCCEEEEEECCCCC
AGSN
CCCC
>Mature Secondary Structure 
ADKKGSTGEKLLYCSFCGKSQHEVKKLIAGPSVFICDECIDLCNEIIRDEAAISEKEGG
CCCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHCCCC
LAVKSDLPTPHEIRQSLDQYVIGQEQAKKILAVAVYNHYKRLKHLGKKDDVELSKSNILL
EEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCEEE
IGPTGSGKTLLAQTLARLLNVPFVIADATTLTEAGYVGEDVENIIQKLLQNCNYEVDKAQ
EECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHHCCCEEHHHC
RGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTMASVPPQGGRKHPNQDFLQ
CCEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEE
VDTTNILFICGGAFDGLEKIITQRSDKSGIGFGAEVKSKEERDVNEVLPQVEPEDLIKFG
EECCEEEEEECCCHHHHHHHHHCCCCCCCCCCCCCCCCCHHCCHHHHCCCCCHHHHHHHC
LIPELIGRLPVVATLAKLDEAALMEILVEPKNAIVKQYQKLLAMEGVELEIRPSALTAIA
CHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHH
RKAIKRKTGARGLRSIVEHALMDVMYDLPNHKGVQKVVIDESTIAGDGKPLLMYEEQPKV
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCEECCCCCEEEEEECCCCC
AGSN
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA