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The map label for this gene is mdtA [H]

Identifier: 17546372

GI number: 17546372

Start: 1777212

End: 1778420

Strand: Direct

Name: mdtA [H]

Synonym: RSc1653

Alternate gene names: 17546372

Gene position: 1777212-1778420 (Clockwise)

Preceding gene: 17546370

Following gene: 17546373

Centisome position: 47.82

GC content: 70.39

Gene sequence:

>1209_bases
ATGCCCGTGTTGCGCCTGCCGTACCCGCATTCCGACTCCACCGGTTCTTTTTTCGCGCCGTTTCTGCCGCGCAGGCGCGC
TTTTCCTGCTGTTTCCGGGGCGCTTCTCCTGGGGGGCGCGCTGCTGTTGGCGGGGTGCGGCAAAGAGCAACCCAAGGCAC
CCGAGGTGCGGCCGGTCCGGACCATGACCGTGGTCAGCGAGCAGGCCGCCGGTACCGTCGAATTCTCCGGCGATGTGCGC
CCGCGCGTCGAGTCGCGGCTGGGTTTCCGCGTGCCGGGCAAGATCATCGCGCGGCTGGTGGACGTTGGCGCCACGGTCAG
GAAAGGCCAGGTGCTGGCGCGGCTGGACCCGACCGACCTGGCGCTGGCGCAGCAATCCGCCCAGGCGCAGTTGCAGGCGG
CCAAGACCGACCGCGATCTGGCGGCGTCCGACCTCAAGCGTTTTTCCGAACTGTTCGCCAAGGGCTTCATCAGCGCGGCC
GAGCAGCAGCGCCACCAGGCCAATTACGATGCAGCCCAGGCGCGCTACGACCAGGCGGTCGCGGGCTACCGCAACCAGTC
CAACCAGGCGGCCTATGCCACGCTGGAAGCCGACGCCGATGGCGTGGTGACGAGCGTGGATGCCGAGGTCGGCCAGGTGG
TCACCGCCGGCCAGCCGGTGGTGCGCGTGGCGCAGACGGCCGAGAAAGAGGTGGTGGTCGGCATTCCCGAAGACCAGGTC
GATGCGCTGCGCAAGTCGCCCGACGTGCGCGTCAAGCTGTGGGCCGACCCGTCGCGCAGCCTGCCCGGCAAGGTGCGCGA
GATCGCGCCGGCGGCCGACCCCGTCACGCGGACATACACCGTGAAGATCACCGTGCCGAATCCGCCGCCCGATCTCAAGC
TGGGCATGACGGCGGTGGCCACCTTCGTGCGTCCGGGCGGCGGCGCGGACAGCGGCGGCATGGGCGTGCGCGTACCGATC
ACGGCCTTGCTGCAGGAGCAGGGCAAAAACGTGGTGTGGCTCTATGACGCGGCGTCGCAGACGGTCAAGCCGGTGCCGGT
GACGGTGGGCGCGCCGCGCGACAACGTGCTGCTGGTGACCGGCGGCCTGTCGCCCGGCCAGACCATCGTCACGGCGGGTG
TGCATCTGCTCAAGGCCGGCCAGCACGTGATGCCGATGGCGGCGGCGGACCAGCCGTCGGCCCAGTCGGCCATCACGCCG
CGGCGCTGA

Upstream 100 bases:

>100_bases
AAAGTCAGTGGGCGAACCGGTCGATGGCATCTTCCTCGTTGACCCTTCGCGAGCCGGTGGTTACATTACTGACCGGTCAG
TTATTTACTGAGAGCGTGTC

Downstream 100 bases:

>100_bases
GCGCCAAGCTTCCGAGCCACGTTTCGCCGCTTCCGGCCCTCTGCCCAATTTCGCCTCATTGCGCGCATGGAACACTCCCG
TTTCAACCTGTCACGCTGGG

Product: transport/efflux transmembrane protein

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MPVLRLPYPHSDSTGSFFAPFLPRRRAFPAVSGALLLGGALLLAGCGKEQPKAPEVRPVRTMTVVSEQAAGTVEFSGDVR
PRVESRLGFRVPGKIIARLVDVGATVRKGQVLARLDPTDLALAQQSAQAQLQAAKTDRDLAASDLKRFSELFAKGFISAA
EQQRHQANYDAAQARYDQAVAGYRNQSNQAAYATLEADADGVVTSVDAEVGQVVTAGQPVVRVAQTAEKEVVVGIPEDQV
DALRKSPDVRVKLWADPSRSLPGKVREIAPAADPVTRTYTVKITVPNPPPDLKLGMTAVATFVRPGGGADSGGMGVRVPI
TALLQEQGKNVVWLYDAASQTVKPVPVTVGAPRDNVLLVTGGLSPGQTIVTAGVHLLKAGQHVMPMAAADQPSAQSAITP
RR

Sequences:

>Translated_402_residues
MPVLRLPYPHSDSTGSFFAPFLPRRRAFPAVSGALLLGGALLLAGCGKEQPKAPEVRPVRTMTVVSEQAAGTVEFSGDVR
PRVESRLGFRVPGKIIARLVDVGATVRKGQVLARLDPTDLALAQQSAQAQLQAAKTDRDLAASDLKRFSELFAKGFISAA
EQQRHQANYDAAQARYDQAVAGYRNQSNQAAYATLEADADGVVTSVDAEVGQVVTAGQPVVRVAQTAEKEVVVGIPEDQV
DALRKSPDVRVKLWADPSRSLPGKVREIAPAADPVTRTYTVKITVPNPPPDLKLGMTAVATFVRPGGGADSGGMGVRVPI
TALLQEQGKNVVWLYDAASQTVKPVPVTVGAPRDNVLLVTGGLSPGQTIVTAGVHLLKAGQHVMPMAAADQPSAQSAITP
RR
>Mature_401_residues
PVLRLPYPHSDSTGSFFAPFLPRRRAFPAVSGALLLGGALLLAGCGKEQPKAPEVRPVRTMTVVSEQAAGTVEFSGDVRP
RVESRLGFRVPGKIIARLVDVGATVRKGQVLARLDPTDLALAQQSAQAQLQAAKTDRDLAASDLKRFSELFAKGFISAAE
QQRHQANYDAAQARYDQAVAGYRNQSNQAAYATLEADADGVVTSVDAEVGQVVTAGQPVVRVAQTAEKEVVVGIPEDQVD
ALRKSPDVRVKLWADPSRSLPGKVREIAPAADPVTRTYTVKITVPNPPPDLKLGMTAVATFVRPGGGADSGGMGVRVPIT
ALLQEQGKNVVWLYDAASQTVKPVPVTVGAPRDNVLLVTGGLSPGQTIVTAGVHLLKAGQHVMPMAAADQPSAQSAITPR
R

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=319, Percent_Identity=25.705329153605, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI87081951, Length=182, Percent_Identity=27.4725274725275, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42402; Mature: 42271

Theoretical pI: Translated: 10.08; Mature: 10.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVLRLPYPHSDSTGSFFAPFLPRRRAFPAVSGALLLGGALLLAGCGKEQPKAPEVRPVR
CCCEECCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCCEE
TMTVVSEQAAGTVEFSGDVRPRVESRLGFRVPGKIIARLVDVGATVRKGQVLARLDPTDL
EEEEEHHCCCCEEEECCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCHHH
ALAQQSAQAQLQAAKTDRDLAASDLKRFSELFAKGFISAAEQQRHQANYDAAQARYDQAV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AGYRNQSNQAAYATLEADADGVVTSVDAEVGQVVTAGQPVVRVAQTAEKEVVVGIPEDQV
HCCCCCCCCEEEEEEECCCCCEEEECCHHHHHEEECCCHHHHHHHHCCCEEEEECCHHHH
DALRKSPDVRVKLWADPSRSLPGKVREIAPAADPVTRTYTVKITVPNPPPDLKLGMTAVA
HHHHCCCCCEEEEECCCCCCCCCHHHHHCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHH
TFVRPGGGADSGGMGVRVPITALLQEQGKNVVWLYDAASQTVKPVPVTVGAPRDNVLLVT
HHHCCCCCCCCCCCEEEHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCCCCCEEEEE
GGLSPGQTIVTAGVHLLKAGQHVMPMAAADQPSAQSAITPRR
CCCCCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PVLRLPYPHSDSTGSFFAPFLPRRRAFPAVSGALLLGGALLLAGCGKEQPKAPEVRPVR
CCEECCCCCCCCCCCEECCCCCCCCCCCHHHHHHHHHHHHHEECCCCCCCCCCCCCCEE
TMTVVSEQAAGTVEFSGDVRPRVESRLGFRVPGKIIARLVDVGATVRKGQVLARLDPTDL
EEEEEHHCCCCEEEECCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCCCEEEEEECCHHH
ALAQQSAQAQLQAAKTDRDLAASDLKRFSELFAKGFISAAEQQRHQANYDAAQARYDQAV
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
AGYRNQSNQAAYATLEADADGVVTSVDAEVGQVVTAGQPVVRVAQTAEKEVVVGIPEDQV
HCCCCCCCCEEEEEEECCCCCEEEECCHHHHHEEECCCHHHHHHHHCCCEEEEECCHHHH
DALRKSPDVRVKLWADPSRSLPGKVREIAPAADPVTRTYTVKITVPNPPPDLKLGMTAVA
HHHHCCCCCEEEEECCCCCCCCCHHHHHCCCCCCCEEEEEEEEECCCCCCCCCHHHHHHH
TFVRPGGGADSGGMGVRVPITALLQEQGKNVVWLYDAASQTVKPVPVTVGAPRDNVLLVT
HHHCCCCCCCCCCCEEEHHHHHHHHHHCCCEEEEECCCCCCCCCCEEEECCCCCCEEEEE
GGLSPGQTIVTAGVHLLKAGQHVMPMAAADQPSAQSAITPRR
CCCCCCCHHHHHHHHHHHCCCCEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]