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The map label for this gene is aroC [H]

Identifier: 17546285

GI number: 17546285

Start: 1681674

End: 1682774

Strand: Direct

Name: aroC [H]

Synonym: RSc1566

Alternate gene names: 17546285

Gene position: 1681674-1682774 (Clockwise)

Preceding gene: 17546284

Following gene: 17546287

Centisome position: 45.25

GC content: 69.3

Gene sequence:

>1101_bases
ATGTCTGGCAATACCCTGGGCCTGCTGTTTTCCGTCACCACCTTCGGCGAGTCGCACGGCCCGGCCATCGGTGCCGTCAT
CGACGGCTGCCCGCCGGGCATGGCGCTGTCGGCCGAGGACATCCAGCCCGATCTCGACCGCCGCAAGCCCGGCACCTCGC
GCCACGTCACGCAGCGCAAGGAAGAAGACCTTGTCGAGATCCTGTCCGGCGTGTTCGAGGGCAAGACCACCGGCACGCCC
ATCTGCCTGCTGATCCGCAACACCGACCAGCGCAGCAAGGACTACGGCAACATCGTCGAGACCTTCCGCCCGGGCCATGC
CGACTACACCTACTGGCACAAGTACGGCATCCGCGACCCGCGCGGCGGCGGCCGTTCGTCGGCCCGGCTGACGGCGCCCG
TGGTGGCGGCCGGCGCCGTCGCCAAGAAATGGCTGCGCGAGAAGTTCGGCGTCGAGATCCACGGCTACATGTCGCAGCTG
GGCGAGATCCGGATTCCGTTCCTCGACTGGAACGAGGTGCCGAACAACCCGTTCTTCGCGCCCAACGCCGAGATCCTCCC
CGAGCTCGAAACCTACATGGACGCGCTGCGCCGCGACGGCGACTCCGTCGGCGCGCGCATCGAGGTGGTGGCGACCGGCA
TGCCGGTCGGCTGGGGCGAGCCGCTGTTCGACCGCCTGGACGCCGACATCGCCCATGCCATGATGGGCCTGAATGCAGTG
AAGGGCGTGGAGATCGGCGCGGGCTTTCATGCCGTGTCGCAGCGCGGCTCCGAGCACGGCGACGAACTGACGCCGGCCGG
CTTCGTCGGCAACAACGCGGGCGGTATCCTGGGCGGCATTTCCACCGGGCAGGACATCTCGGTATCGCTGGCGATCAAGC
CGACCTCCAGCATCCGCACGCCGCGCCGCTCGATCGACAAGGCGGGCGAGCCGACCGCGGTCGAGACGTTCGGCCGCCAC
GATCCGTGTGTCGGTATCCGCGCCACGCCGATCGCCGAGGCGCTGCTGGCGCTGGTGCTGACCGACCATGCGCTGCGCCA
TCGTGCCCAATGCGGCGACGTGGCGGTGGCGACCCCGGCCATCGCCGCCAAGGCGCCGTAA

Upstream 100 bases:

>100_bases
TCGAGCTGCTCGGCATCGGCGGCTGATCCGTCAGCCTTACAATAGCGGTTTCCCGATGTTTCGCGCCACGCACCGCCGTG
GCGCCTTTCCGAGCACGATC

Downstream 100 bases:

>100_bases
GGCGATCCGCGCAGGCCACAAAAAAGACGGCGCGAAGCCGTCTTTTTTGTTGGGCGCCAGGCACTTACATGCCGACGTAG
TTCGGGCCGCCGCCGCCTTC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase [H]

Number of amino acids: Translated: 366; Mature: 365

Protein sequence:

>366_residues
MSGNTLGLLFSVTTFGESHGPAIGAVIDGCPPGMALSAEDIQPDLDRRKPGTSRHVTQRKEEDLVEILSGVFEGKTTGTP
ICLLIRNTDQRSKDYGNIVETFRPGHADYTYWHKYGIRDPRGGGRSSARLTAPVVAAGAVAKKWLREKFGVEIHGYMSQL
GEIRIPFLDWNEVPNNPFFAPNAEILPELETYMDALRRDGDSVGARIEVVATGMPVGWGEPLFDRLDADIAHAMMGLNAV
KGVEIGAGFHAVSQRGSEHGDELTPAGFVGNNAGGILGGISTGQDISVSLAIKPTSSIRTPRRSIDKAGEPTAVETFGRH
DPCVGIRATPIAEALLALVLTDHALRHRAQCGDVAVATPAIAAKAP

Sequences:

>Translated_366_residues
MSGNTLGLLFSVTTFGESHGPAIGAVIDGCPPGMALSAEDIQPDLDRRKPGTSRHVTQRKEEDLVEILSGVFEGKTTGTP
ICLLIRNTDQRSKDYGNIVETFRPGHADYTYWHKYGIRDPRGGGRSSARLTAPVVAAGAVAKKWLREKFGVEIHGYMSQL
GEIRIPFLDWNEVPNNPFFAPNAEILPELETYMDALRRDGDSVGARIEVVATGMPVGWGEPLFDRLDADIAHAMMGLNAV
KGVEIGAGFHAVSQRGSEHGDELTPAGFVGNNAGGILGGISTGQDISVSLAIKPTSSIRTPRRSIDKAGEPTAVETFGRH
DPCVGIRATPIAEALLALVLTDHALRHRAQCGDVAVATPAIAAKAP
>Mature_365_residues
SGNTLGLLFSVTTFGESHGPAIGAVIDGCPPGMALSAEDIQPDLDRRKPGTSRHVTQRKEEDLVEILSGVFEGKTTGTPI
CLLIRNTDQRSKDYGNIVETFRPGHADYTYWHKYGIRDPRGGGRSSARLTAPVVAAGAVAKKWLREKFGVEIHGYMSQLG
EIRIPFLDWNEVPNNPFFAPNAEILPELETYMDALRRDGDSVGARIEVVATGMPVGWGEPLFDRLDADIAHAMMGLNAVK
GVEIGAGFHAVSQRGSEHGDELTPAGFVGNNAGGILGGISTGQDISVSLAIKPTSSIRTPRRSIDKAGEPTAVETFGRHD
PCVGIRATPIAEALLALVLTDHALRHRAQCGDVAVATPAIAAKAP

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1788669, Length=359, Percent_Identity=62.9526462395543, Blast_Score=445, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6321290, Length=369, Percent_Identity=42.5474254742547, Blast_Score=285, Evalue=7e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000453
- InterPro:   IPR020541 [H]

Pfam domain/function: PF01264 Chorismate_synt [H]

EC number: =4.2.3.5 [H]

Molecular weight: Translated: 38987; Mature: 38855

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1 ; PS00788 CHORISMATE_SYNTHASE_2 ; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGNTLGLLFSVTTFGESHGPAIGAVIDGCPPGMALSAEDIQPDLDRRKPGTSRHVTQRK
CCCCEEEEEEEEEECCCCCCCEEEEEECCCCCCCEECHHHCCCCHHHCCCCCCHHHHHHH
EEDLVEILSGVFEGKTTGTPICLLIRNTDQRSKDYGNIVETFRPGHADYTYWHKYGIRDP
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCC
RGGGRSSARLTAPVVAAGAVAKKWLREKFGVEIHGYMSQLGEIRIPFLDWNEVPNNPFFA
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCEEHHHHHHCCCEEEEEECCCCCCCCCCCC
PNAEILPELETYMDALRRDGDSVGARIEVVATGMPVGWGEPLFDRLDADIAHAMMGLNAV
CCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGAGFHAVSQRGSEHGDELTPAGFVGNNAGGILGGISTGQDISVSLAIKPTSSIRT
CCEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCHHHCC
PRRSIDKAGEPTAVETFGRHDPCVGIRATPIAEALLALVLTDHALRHRAQCGDVAVATPA
CHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
IAAKAP
HHCCCC
>Mature Secondary Structure 
SGNTLGLLFSVTTFGESHGPAIGAVIDGCPPGMALSAEDIQPDLDRRKPGTSRHVTQRK
CCCEEEEEEEEEECCCCCCCEEEEEECCCCCCCEECHHHCCCCHHHCCCCCCHHHHHHH
EEDLVEILSGVFEGKTTGTPICLLIRNTDQRSKDYGNIVETFRPGHADYTYWHKYGIRDP
HHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCCHHHHCCCCCC
RGGGRSSARLTAPVVAAGAVAKKWLREKFGVEIHGYMSQLGEIRIPFLDWNEVPNNPFFA
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHCCEEHHHHHHCCCEEEEEECCCCCCCCCCCC
PNAEILPELETYMDALRRDGDSVGARIEVVATGMPVGWGEPLFDRLDADIAHAMMGLNAV
CCHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHH
KGVEIGAGFHAVSQRGSEHGDELTPAGFVGNNAGGILGGISTGQDISVSLAIKPTSSIRT
CCEEECCCHHHHHHCCCCCCCCCCCCCCCCCCCCCEEECCCCCCCEEEEEEECCCHHHCC
PRRSIDKAGEPTAVETFGRHDPCVGIRATPIAEALLALVLTDHALRHRAQCGDVAVATPA
CHHHHHCCCCCCHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCC
IAAKAP
HHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA