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The map label for this gene is senX3 [H]

Identifier: 17545794

GI number: 17545794

Start: 1129767

End: 1132121

Strand: Direct

Name: senX3 [H]

Synonym: RSc1075

Alternate gene names: 17545794

Gene position: 1129767-1132121 (Clockwise)

Preceding gene: 17545793

Following gene: 17545795

Centisome position: 30.4

GC content: 73.04

Gene sequence:

>2355_bases
ATGACCGGTCCGGCAACGCCCGTTCCCGATAGGCAGGCGGCCCGCGCCGTGGCGCTGCGGCCGGGGTTGCGTGCGCTGCT
GGAGTGGGTGCTGCTGGTGGCGCTGGCCGTGCTGCTGACGTTCGGCGCGGTGCGCTGGAGCGTGGTGGCGCGCCTGGATG
CGGCGCTCTACGACACGGTGCTGTCGCTGCATGGCCACGCGCCGCGCGACGATATCGTCATTGTCGCCATCGACGACCAG
AGCCTCGAAGCCGTCGGCCGCTGGCCCTGGCCGCGTGCGCGCCTGGCTGAACTGGTGGCGCGCGTGGGCGCGGCGCATCC
GCGTGCGGTCGGCGTCGATATCCTGCTGATCGAACCCGATCTGACCGACCCGGAAGGCGATCGCGCGCTGGCGGCGGCCT
TTGCGCAGGCGGGCCAGGTCATCCTGCCGGCGCTGCCCGAGCGCACCGGGCAGGGGCGGGTGTTCCACTATCCCTTCCTC
GGGATCGGCACGCACGTCGCGCACATCGATGCGGCGCCCGACCCGGACAGCGTGGTGCGCGGTCTCTACCTGGCCGAGGG
CCCGCGCGGACATCTGCTCGACCACCTCGCGCTGCAGCTGGCCCGGCAGGCAGGCCCCGCACTGGCGGGCGACGTGCCGC
GCCGCACGGAGATCGATGCCGACGGCTGGGCGCGCCGGGCCAACATTGGCGTGAACTTTGCCGGGCCGGCGGGCACGTTC
CGGCATGTGCCCGCGCTGACCCTGCTGCAAGGCGGGGTGCCGGCCGACGCCTTCTCGGGCAAGCTGGTGCTGATCGGCGC
GACGGCATCCGGCGTGTCCGATATCTTTGCCACGCCGACCTCGCGCACGATGAGCGGCGTGGAGGTGCTGGCCAACGCCA
CGCAGACCCTGCTCGACGGCAATGCGATCCTGCCTGCCTCGCGCACCGTGTTCTGGCTGGTGACGCTGCTGCCGCTGAGC
CTGACCGCGTGCGCGCTGCTCTGGCTGACACCGCGCATGGCGCTGACGGCGGCGCTGGGGAGCGCGGGGCTGCTGCTGGT
GGGCGTGGTGGCGGCGCTGGCCGGCTGGAACCGCTGGCTGCCGCCGTTCGCGGCGCTGGTCGGGCCGCTGGTGCTGTACC
CGCTGTGGAGCTGGCGGCAGCAGGAGGCGGCGCTGCGCTTCCTGCGCGACGAGCTGCACCGGCTGGCGCGCGAGCCGGGC
CTGCTGGCCGGCACCGGCCCGCTGGCGCAGACCGGCCGTACGCTGGATGCCCATATGGACGCAGTGGCGTCGCTCACCGA
CAAGCTGCGCGGGCTGCGCCGCTTCCTCGCCGAAGCGCTGGAGAGCCTGCCCGACGCCACCGTCATCTGCACGCACGACG
GCGACATCCGCCTGGCCAACGGGCGCAGCGCCGACCTCGCGGCGCAGGCGCCGGTGTCCGGGCAGGACCGCGCCGCCGCC
CTGCGCGATCTGCCGACCCTGCTGGCCTGCGCCTTTGAGGATCCGGCACCCGGCCAGCACTACTGGACACGCTGGCTGAC
CGCGCCCGACACCGCGCAGGAACCGGTGGAGCTGCGCACGCGCGACGGGCGCTCGATGCTGATGCATGCGGCCGCGCTGC
GCGACGATGCCGGCCGGCCGATGGACATCATCGTCAGCTTCGCCGACATCACCGCCGTGCGGCAGGCCGAGCGCCACCGC
GAGGAGGCGCTGCGCTTCATCTCGCACGACATGCGCTCGCCGCAGAGCGCCATCCTGGCGCTGATCGAGCTGCAGCGCGA
TGCGGGCCGGGCGCTCGGCCACGAGGCACTGCTGGCGCGCATCCAGCAGCTGTCGTCGCGGACGCTGGAGCTGGCCGATG
CCTTCATCGACCTGGCGCGTGTGGAATCGCAGGAGCTCAAGCTGACCGACGTGGACCTGGTCGGCCTCGTGCTCGATGCC
GCCGACGAGGTCTGGGCGCTGGCGAACCATCACCAGATCGAGGTGCGCGTCGATGCCGATCTCGAGGCTTCGGTGCGCGG
CGAGCCGCGCATGCTGGTCCGTGCGCTGGTCAACCTGGTGAACAACGCCATCAAGTTCAGCCCGCGCGGCACGACCGTCA
CGGTGGCCGTACGCGGGGACGCGGACAGCTTCGCCGTGAGCGTGGCGGACCAGGGCGTGGGCATCGCGGCCGAGGACCAG
GCGCAGCTGTTCCAGCCGTTCCGCCGGCTGCATGAGGCGGTGGCCGATGCGCCATCGGGCAGCGGCCTGGGGCTGGTGTT
CGTCAAGACGGTGGTGGAGCGGCACGGCGGTCGCATCGCGGTGCGGAGCGTGCCTGGGCACGGGGCGACCTTCACGCTGT
GGCTGCCGCGCGCATCGCGTCCCGGGGCGTTCTGA

Upstream 100 bases:

>100_bases
TCGGTGGTGTTCGCGCGGCCGCAGCGCATCGACATCGGCAGTTTCGTCGTCGATGCGCTGGGTGCGCCCGTGCAGAGCAG
CGGGTCGAGCCTCCTCCTTG

Downstream 100 bases:

>100_bases
CCGGAATGCGCATCTGGCGCGCACAGGTTGGACACAAACCATTTTCAATCATTTGCATTCCCCCTACGTTGTGCGCCTAC
ATTTGCATGGCCGACCGGCG

Product: two-component system sensor histidine kinase transcription regulator protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 784; Mature: 783

Protein sequence:

>784_residues
MTGPATPVPDRQAARAVALRPGLRALLEWVLLVALAVLLTFGAVRWSVVARLDAALYDTVLSLHGHAPRDDIVIVAIDDQ
SLEAVGRWPWPRARLAELVARVGAAHPRAVGVDILLIEPDLTDPEGDRALAAAFAQAGQVILPALPERTGQGRVFHYPFL
GIGTHVAHIDAAPDPDSVVRGLYLAEGPRGHLLDHLALQLARQAGPALAGDVPRRTEIDADGWARRANIGVNFAGPAGTF
RHVPALTLLQGGVPADAFSGKLVLIGATASGVSDIFATPTSRTMSGVEVLANATQTLLDGNAILPASRTVFWLVTLLPLS
LTACALLWLTPRMALTAALGSAGLLLVGVVAALAGWNRWLPPFAALVGPLVLYPLWSWRQQEAALRFLRDELHRLAREPG
LLAGTGPLAQTGRTLDAHMDAVASLTDKLRGLRRFLAEALESLPDATVICTHDGDIRLANGRSADLAAQAPVSGQDRAAA
LRDLPTLLACAFEDPAPGQHYWTRWLTAPDTAQEPVELRTRDGRSMLMHAAALRDDAGRPMDIIVSFADITAVRQAERHR
EEALRFISHDMRSPQSAILALIELQRDAGRALGHEALLARIQQLSSRTLELADAFIDLARVESQELKLTDVDLVGLVLDA
ADEVWALANHHQIEVRVDADLEASVRGEPRMLVRALVNLVNNAIKFSPRGTTVTVAVRGDADSFAVSVADQGVGIAAEDQ
AQLFQPFRRLHEAVADAPSGSGLGLVFVKTVVERHGGRIAVRSVPGHGATFTLWLPRASRPGAF

Sequences:

>Translated_784_residues
MTGPATPVPDRQAARAVALRPGLRALLEWVLLVALAVLLTFGAVRWSVVARLDAALYDTVLSLHGHAPRDDIVIVAIDDQ
SLEAVGRWPWPRARLAELVARVGAAHPRAVGVDILLIEPDLTDPEGDRALAAAFAQAGQVILPALPERTGQGRVFHYPFL
GIGTHVAHIDAAPDPDSVVRGLYLAEGPRGHLLDHLALQLARQAGPALAGDVPRRTEIDADGWARRANIGVNFAGPAGTF
RHVPALTLLQGGVPADAFSGKLVLIGATASGVSDIFATPTSRTMSGVEVLANATQTLLDGNAILPASRTVFWLVTLLPLS
LTACALLWLTPRMALTAALGSAGLLLVGVVAALAGWNRWLPPFAALVGPLVLYPLWSWRQQEAALRFLRDELHRLAREPG
LLAGTGPLAQTGRTLDAHMDAVASLTDKLRGLRRFLAEALESLPDATVICTHDGDIRLANGRSADLAAQAPVSGQDRAAA
LRDLPTLLACAFEDPAPGQHYWTRWLTAPDTAQEPVELRTRDGRSMLMHAAALRDDAGRPMDIIVSFADITAVRQAERHR
EEALRFISHDMRSPQSAILALIELQRDAGRALGHEALLARIQQLSSRTLELADAFIDLARVESQELKLTDVDLVGLVLDA
ADEVWALANHHQIEVRVDADLEASVRGEPRMLVRALVNLVNNAIKFSPRGTTVTVAVRGDADSFAVSVADQGVGIAAEDQ
AQLFQPFRRLHEAVADAPSGSGLGLVFVKTVVERHGGRIAVRSVPGHGATFTLWLPRASRPGAF
>Mature_783_residues
TGPATPVPDRQAARAVALRPGLRALLEWVLLVALAVLLTFGAVRWSVVARLDAALYDTVLSLHGHAPRDDIVIVAIDDQS
LEAVGRWPWPRARLAELVARVGAAHPRAVGVDILLIEPDLTDPEGDRALAAAFAQAGQVILPALPERTGQGRVFHYPFLG
IGTHVAHIDAAPDPDSVVRGLYLAEGPRGHLLDHLALQLARQAGPALAGDVPRRTEIDADGWARRANIGVNFAGPAGTFR
HVPALTLLQGGVPADAFSGKLVLIGATASGVSDIFATPTSRTMSGVEVLANATQTLLDGNAILPASRTVFWLVTLLPLSL
TACALLWLTPRMALTAALGSAGLLLVGVVAALAGWNRWLPPFAALVGPLVLYPLWSWRQQEAALRFLRDELHRLAREPGL
LAGTGPLAQTGRTLDAHMDAVASLTDKLRGLRRFLAEALESLPDATVICTHDGDIRLANGRSADLAAQAPVSGQDRAAAL
RDLPTLLACAFEDPAPGQHYWTRWLTAPDTAQEPVELRTRDGRSMLMHAAALRDDAGRPMDIIVSFADITAVRQAERHRE
EALRFISHDMRSPQSAILALIELQRDAGRALGHEALLARIQQLSSRTLELADAFIDLARVESQELKLTDVDLVGLVLDAA
DEVWALANHHQIEVRVDADLEASVRGEPRMLVRALVNLVNNAIKFSPRGTTVTVAVRGDADSFAVSVADQGVGIAAEDQA
QLFQPFRRLHEAVADAPSGSGLGLVFVKTVVERHGGRIAVRSVPGHGATFTLWLPRASRPGAF

Specific function: Probably forms part of a two-component regulatory system senX3/regX3. Phosphorylates regX3 (Probable) [H]

COG id: COG4252

COG function: function code T; Predicted transmembrane sensor domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI145693157, Length=235, Percent_Identity=29.7872340425532, Blast_Score=106, Evalue=6e-24,
Organism=Escherichia coli, GI1786600, Length=350, Percent_Identity=26.2857142857143, Blast_Score=101, Evalue=2e-22,
Organism=Escherichia coli, GI1789149, Length=226, Percent_Identity=27.8761061946903, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1790436, Length=212, Percent_Identity=32.0754716981132, Blast_Score=94, Evalue=5e-20,
Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790346, Length=247, Percent_Identity=27.1255060728745, Blast_Score=87, Evalue=5e-18,
Organism=Escherichia coli, GI1786783, Length=217, Percent_Identity=30.8755760368664, Blast_Score=87, Evalue=6e-18,
Organism=Escherichia coli, GI1788549, Length=259, Percent_Identity=26.6409266409266, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI48994928, Length=288, Percent_Identity=27.0833333333333, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1790861, Length=224, Percent_Identity=28.125, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081816, Length=117, Percent_Identity=32.4786324786325, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789808, Length=228, Percent_Identity=28.0701754385965, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=26.0330578512397, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI87082128, Length=233, Percent_Identity=25.3218884120172, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1788393, Length=228, Percent_Identity=23.2456140350877, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 83835; Mature: 83704

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGPATPVPDRQAARAVALRPGLRALLEWVLLVALAVLLTFGAVRWSVVARLDAALYDTV
CCCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSLHGHAPRDDIVIVAIDDQSLEAVGRWPWPRARLAELVARVGAAHPRAVGVDILLIEPD
HHHCCCCCCCCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCC
LTDPEGDRALAAAFAQAGQVILPALPERTGQGRVFHYPFLGIGTHVAHIDAAPDPDSVVR
CCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCEEEECCCCCCCEEEEECCCCCHHHHHH
GLYLAEGPRGHLLDHLALQLARQAGPALAGDVPRRTEIDADGWARRANIGVNFAGPAGTF
HHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCEEECCCCCCH
RHVPALTLLQGGVPADAFSGKLVLIGATASGVSDIFATPTSRTMSGVEVLANATQTLLDG
HHCCHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCC
NAILPASRTVFWLVTLLPLSLTACALLWLTPRMALTAALGSAGLLLVGVVAALAGWNRWL
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
PPFAALVGPLVLYPLWSWRQQEAALRFLRDELHRLAREPGLLAGTGPLAQTGRTLDAHMD
CHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHCCCCHHHHHH
AVASLTDKLRGLRRFLAEALESLPDATVICTHDGDIRLANGRSADLAAQAPVSGQDRAAA
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCCCCCCEECCCCCCCHHHHH
LRDLPTLLACAFEDPAPGQHYWTRWLTAPDTAQEPVELRTRDGRSMLMHAAALRDDAGRP
HHHHHHHHHHHCCCCCCCCHHHHHEECCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCC
MDIIVSFADITAVRQAERHREEALRFISHDMRSPQSAILALIELQRDAGRALGHEALLAR
HHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQQLSSRTLELADAFIDLARVESQELKLTDVDLVGLVLDAADEVWALANHHQIEVRVDAD
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
LEASVRGEPRMLVRALVNLVNNAIKFSPRGTTVTVAVRGDADSFAVSVADQGVGIAAEDQ
CCCCCCCCHHHHHHHHHHHHHHHEEECCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCH
AQLFQPFRRLHEAVADAPSGSGLGLVFVKTVVERHGGRIAVRSVPGHGATFTLWLPRASR
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCC
PGAF
CCCC
>Mature Secondary Structure 
TGPATPVPDRQAARAVALRPGLRALLEWVLLVALAVLLTFGAVRWSVVARLDAALYDTV
CCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSLHGHAPRDDIVIVAIDDQSLEAVGRWPWPRARLAELVARVGAAHPRAVGVDILLIEPD
HHHCCCCCCCCEEEEEECCCCHHHHCCCCCCHHHHHHHHHHHCCCCCCCCCEEEEEECCC
LTDPEGDRALAAAFAQAGQVILPALPERTGQGRVFHYPFLGIGTHVAHIDAAPDPDSVVR
CCCCCCCHHHHHHHHHCCCEEECCCCCCCCCCCEEEECCCCCCCEEEEECCCCCHHHHHH
GLYLAEGPRGHLLDHLALQLARQAGPALAGDVPRRTEIDADGWARRANIGVNFAGPAGTF
HHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEECCCCEEECCCCCCH
RHVPALTLLQGGVPADAFSGKLVLIGATASGVSDIFATPTSRTMSGVEVLANATQTLLDG
HHCCHHHHHCCCCCCCCCCCEEEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHHHHHHCC
NAILPASRTVFWLVTLLPLSLTACALLWLTPRMALTAALGSAGLLLVGVVAALAGWNRWL
CEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
PPFAALVGPLVLYPLWSWRQQEAALRFLRDELHRLAREPGLLAGTGPLAQTGRTLDAHMD
CHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHCCCCHHHHHH
AVASLTDKLRGLRRFLAEALESLPDATVICTHDGDIRLANGRSADLAAQAPVSGQDRAAA
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCEEECCCCCCCCEECCCCCCCHHHHH
LRDLPTLLACAFEDPAPGQHYWTRWLTAPDTAQEPVELRTRDGRSMLMHAAALRDDAGRP
HHHHHHHHHHHCCCCCCCCHHHHHEECCCCCCCCCHHHHCCCCHHHHHHHHHHHCCCCCC
MDIIVSFADITAVRQAERHREEALRFISHDMRSPQSAILALIELQRDAGRALGHEALLAR
HHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQQLSSRTLELADAFIDLARVESQELKLTDVDLVGLVLDAADEVWALANHHQIEVRVDAD
HHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
LEASVRGEPRMLVRALVNLVNNAIKFSPRGTTVTVAVRGDADSFAVSVADQGVGIAAEDQ
CCCCCCCCHHHHHHHHHHHHHHHEEECCCCCEEEEEEECCCCCEEEEECCCCCCCCCCCH
AQLFQPFRRLHEAVADAPSGSGLGLVFVKTVVERHGGRIAVRSVPGHGATFTLWLPRASR
HHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCEEEEEECCCCC
PGAF
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9426136; 12788972 [H]