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The map label for this gene is acpS

Identifier: 17545786

GI number: 17545786

Start: 1119910

End: 1120326

Strand: Direct

Name: acpS

Synonym: RSc1067

Alternate gene names: 17545786

Gene position: 1119910-1120326 (Clockwise)

Preceding gene: 17545785

Following gene: 17545787

Centisome position: 30.13

GC content: 67.15

Gene sequence:

>417_bases
GTGTCCGGTGCCATTTATGGCATCGGCACCGACATCATCCAGATCGAGCGCGTCGAAGGCGTGATGCAGCGGACTCACGG
CCGCTTCGCCGAGAAGGTGCTCGGCCCCGATGAACTGCGCATCTACCAGGCCCGCAAGGCCCGCTCGGAGCGGCGCGGCC
TGGCGTTTCTTGCCACGCGCTTTGCCGCCAAGGAGGCGGTCTCCAAGGCCATCGGCCTCGGCATGCACTGGCCGATGACG
TGGCGTGCCGTGCAGACCCTCAACCTGCCGTCCGGCCAGCCGGTGGTGCGATACAGCGGCGAACTGGCCGACTGGATCGC
GCAGCGCGGCCTCCATATCCAGATCAGCGTGACGGACGAGCGCGACTACGCGGTCGCCTTCGCCGTCGCCGAACTGCAAT
CCAAGCTCTCCGCATGA

Upstream 100 bases:

>100_bases
AGATGAAGGCCATCATGGTGGCGGCACGCCTGTCGGCGACGACGCCAGCGGCAGCGCATCCGGGCGTGCCGGCATGAGCG
AACGGCCTGCCGTTCCGCCG

Downstream 100 bases:

>100_bases
ATTCCATCACCAACAAGCAGAAGCGCCCCGGCCCGATCGTCCTCGACGTGGCCGGGCTCGTGCTCGGCCCTGACGATGTC
CGCCGGATCGTGCATCCGCT

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 138; Mature: 137

Protein sequence:

>138_residues
MSGAIYGIGTDIIQIERVEGVMQRTHGRFAEKVLGPDELRIYQARKARSERRGLAFLATRFAAKEAVSKAIGLGMHWPMT
WRAVQTLNLPSGQPVVRYSGELADWIAQRGLHIQISVTDERDYAVAFAVAELQSKLSA

Sequences:

>Translated_138_residues
MSGAIYGIGTDIIQIERVEGVMQRTHGRFAEKVLGPDELRIYQARKARSERRGLAFLATRFAAKEAVSKAIGLGMHWPMT
WRAVQTLNLPSGQPVVRYSGELADWIAQRGLHIQISVTDERDYAVAFAVAELQSKLSA
>Mature_137_residues
SGAIYGIGTDIIQIERVEGVMQRTHGRFAEKVLGPDELRIYQARKARSERRGLAFLATRFAAKEAVSKAIGLGMHWPMTW
RAVQTLNLPSGQPVVRYSGELADWIAQRGLHIQISVTDERDYAVAFAVAELQSKLSA

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=129, Percent_Identity=34.8837209302326, Blast_Score=79, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_RALSO (Q8Y0H7)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_519188.1
- ProteinModelPortal:   Q8Y0H7
- SMR:   Q8Y0H7
- GeneID:   1219876
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc1067
- NMPDR:   fig|267608.1.peg.1067
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- ProtClustDB:   PRK00070
- BioCyc:   RSOL267608:RSC1067-MONOMER
- BRENDA:   2.7.8.7
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 15326; Mature: 15195

Theoretical pI: Translated: 10.14; Mature: 10.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGAIYGIGTDIIQIERVEGVMQRTHGRFAEKVLGPDELRIYQARKARSERRGLAFLATR
CCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHH
FAAKEAVSKAIGLGMHWPMTWRAVQTLNLPSGQPVVRYSGELADWIAQRGLHIQISVTDE
HHHHHHHHHHHCCCCCCCCHHHHEEEECCCCCCCEEEECCHHHHHHHHCCCEEEEEEECC
RDYAVAFAVAELQSKLSA
CCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SGAIYGIGTDIIQIERVEGVMQRTHGRFAEKVLGPDELRIYQARKARSERRGLAFLATR
CCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHHH
FAAKEAVSKAIGLGMHWPMTWRAVQTLNLPSGQPVVRYSGELADWIAQRGLHIQISVTDE
HHHHHHHHHHHCCCCCCCCHHHHEEEECCCCCCCEEEECCHHHHHHHHCCCEEEEEEECC
RDYAVAFAVAELQSKLSA
CCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852