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The map label for this gene is nagZ [H]

Identifier: 17545787

GI number: 17545787

Start: 1120323

End: 1121375

Strand: Direct

Name: nagZ [H]

Synonym: RSc1068

Alternate gene names: 17545787

Gene position: 1120323-1121375 (Clockwise)

Preceding gene: 17545786

Following gene: 17545790

Centisome position: 30.15

GC content: 68.47

Gene sequence:

>1053_bases
ATGAATTCCATCACCAACAAGCAGAAGCGCCCCGGCCCGATCGTCCTCGACGTGGCCGGGCTCGTGCTCGGCCCTGACGA
TGTCCGCCGGATCGTGCATCCGCTGACCGGCGGCGTGATCCTGTTCGCGCGCAATTTCGAGTCGCGCGCGCAGTTGACGG
CACTGACCGCCGCGATCCGGGCCATACGCGATGACGTGCTGATCTGCATCGACCACGAGGGTGGGCGCGTGCAGCGTGCC
AAGCAGGACGGCTTCACGCATCTGCCGGCGATGTCCGCGCTGGGGCAGCTGTGGGACCGCGACGTCCTGGCCGCCACGCG
CGCGGCCACCGCGTGCGGCTATGTGCTGGCGGCGGAATTGCGCGGCTGCGACATCGACCTGAGCTTCACGCCGGTGCTGG
ACCTGGACTATGGCACCAGCGGCGTGATCGGTGACCGCGCTTTCCACCGCGATCCGCGCGTGGTGACGATGCTCGCCAAC
CACCTGACGCTGGGCCTGCGCCTGGCCGGCATGGCCAACTGCGGCAAGCATTTCCCCGGCCACGGCTGGGTTCAGGCCGA
TTCGCACGTCGCCGTGCCGGTCGACGAGCGGCCGCTGCAGGCGATCCTCGACGAGGATGCCCAGCCGTACGGGTGGATGG
GCATCGGCCTGCAATCGGTGATGCCGGCGCATGTCATCTATTCGGCGGTCGATCCGAACCCGGCGGGCTTCTCGCGCTTC
TGGCTGCAGGACATCCTGCGCACGCATTACAACTTCGACGGCGTGATCTTCAGCGACGACCTGAGCATGGAAGGCGCCAG
CGTCGCGGGGTCGGTGGTCGACGGCGCGCGCGCGGCGCTGGCGGCCGGCTGCGACATGGTGCTGATCTGCAATGCGCCGG
ACAAGGCCGACCAACTGCTGAACGAACTGGACGTGAGGATCGGCAAGGCTTCGCAGCGACGCATCCGCCGGCTGTTCGGC
ACCAAGGCGGCCAAGGACTGGTCGAAGCTGGCGCAGCAGTCGGCGTACCGGCAGGCGCTGCGGACACTGCGCGAGGCACG
GCTGATCGCCTAG

Upstream 100 bases:

>100_bases
GGATCGCGCAGCGCGGCCTCCATATCCAGATCAGCGTGACGGACGAGCGCGACTACGCGGTCGCCTTCGCCGTCGCCGAA
CTGCAATCCAAGCTCTCCGC

Downstream 100 bases:

>100_bases
CGCGCAGGCGGGTGGGGTGCGAGGTCTTGCTGCGCCATCGCCCGCTCCATCGCTTTTTCGCGGGCAACAAAAAAGGCAGC
GCCAGGCTGCCTTTTTTGTT

Product: beta-hexosaminidase

Products: NA

Alternate protein names: Beta-N-acetylhexosaminidase; N-acetyl-beta-glucosaminidase [H]

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MNSITNKQKRPGPIVLDVAGLVLGPDDVRRIVHPLTGGVILFARNFESRAQLTALTAAIRAIRDDVLICIDHEGGRVQRA
KQDGFTHLPAMSALGQLWDRDVLAATRAATACGYVLAAELRGCDIDLSFTPVLDLDYGTSGVIGDRAFHRDPRVVTMLAN
HLTLGLRLAGMANCGKHFPGHGWVQADSHVAVPVDERPLQAILDEDAQPYGWMGIGLQSVMPAHVIYSAVDPNPAGFSRF
WLQDILRTHYNFDGVIFSDDLSMEGASVAGSVVDGARAALAAGCDMVLICNAPDKADQLLNELDVRIGKASQRRIRRLFG
TKAAKDWSKLAQQSAYRQALRTLREARLIA

Sequences:

>Translated_350_residues
MNSITNKQKRPGPIVLDVAGLVLGPDDVRRIVHPLTGGVILFARNFESRAQLTALTAAIRAIRDDVLICIDHEGGRVQRA
KQDGFTHLPAMSALGQLWDRDVLAATRAATACGYVLAAELRGCDIDLSFTPVLDLDYGTSGVIGDRAFHRDPRVVTMLAN
HLTLGLRLAGMANCGKHFPGHGWVQADSHVAVPVDERPLQAILDEDAQPYGWMGIGLQSVMPAHVIYSAVDPNPAGFSRF
WLQDILRTHYNFDGVIFSDDLSMEGASVAGSVVDGARAALAAGCDMVLICNAPDKADQLLNELDVRIGKASQRRIRRLFG
TKAAKDWSKLAQQSAYRQALRTLREARLIA
>Mature_350_residues
MNSITNKQKRPGPIVLDVAGLVLGPDDVRRIVHPLTGGVILFARNFESRAQLTALTAAIRAIRDDVLICIDHEGGRVQRA
KQDGFTHLPAMSALGQLWDRDVLAATRAATACGYVLAAELRGCDIDLSFTPVLDLDYGTSGVIGDRAFHRDPRVVTMLAN
HLTLGLRLAGMANCGKHFPGHGWVQADSHVAVPVDERPLQAILDEDAQPYGWMGIGLQSVMPAHVIYSAVDPNPAGFSRF
WLQDILRTHYNFDGVIFSDDLSMEGASVAGSVVDGARAALAAGCDMVLICNAPDKADQLLNELDVRIGKASQRRIRRLFG
TKAAKDWSKLAQQSAYRQALRTLREARLIA

Specific function: Cleaves GlcNAc linked beta-1,4 to MurNAc tripeptides [H]

COG id: COG1472

COG function: function code G; Beta-glucosidase-related glycosidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyl hydrolase 3 family. NagZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787350, Length=339, Percent_Identity=41.8879056047198, Blast_Score=251, Evalue=6e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022956
- InterPro:   IPR019800
- InterPro:   IPR001764
- InterPro:   IPR017853 [H]

Pfam domain/function: PF00933 Glyco_hydro_3 [H]

EC number: =3.2.1.52 [H]

Molecular weight: Translated: 38007; Mature: 38007

Theoretical pI: Translated: 7.59; Mature: 7.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSITNKQKRPGPIVLDVAGLVLGPDDVRRIVHPLTGGVILFARNFESRAQLTALTAAIR
CCCCCCCCCCCCCEEEEECCEEECHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHH
AIRDDVLICIDHEGGRVQRAKQDGFTHLPAMSALGQLWDRDVLAATRAATACGYVLAAEL
HHCCCEEEEEECCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGCDIDLSFTPVLDLDYGTSGVIGDRAFHRDPRVVTMLANHLTLGLRLAGMANCGKHFPG
CCCEEEEEECEEEEECCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
HGWVQADSHVAVPVDERPLQAILDEDAQPYGWMGIGLQSVMPAHVIYSAVDPNPAGFSRF
CCCEECCCEEEECCCCCHHHHHHCCCCCCCCEECCCHHHHHHHHHHEECCCCCCCCHHHH
WLQDILRTHYNFDGVIFSDDLSMEGASVAGSVVDGARAALAAGCDMVLICNAPDKADQLL
HHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHH
NELDVRIGKASQRRIRRLFGTKAAKDWSKLAQQSAYRQALRTLREARLIA
HHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNSITNKQKRPGPIVLDVAGLVLGPDDVRRIVHPLTGGVILFARNFESRAQLTALTAAIR
CCCCCCCCCCCCCEEEEECCEEECHHHHHHHHHHHCCCEEEEEECCCHHHHHHHHHHHHH
AIRDDVLICIDHEGGRVQRAKQDGFTHLPAMSALGQLWDRDVLAATRAATACGYVLAAEL
HHCCCEEEEEECCCCCEEHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RGCDIDLSFTPVLDLDYGTSGVIGDRAFHRDPRVVTMLANHLTLGLRLAGMANCGKHFPG
CCCEEEEEECEEEEECCCCCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCC
HGWVQADSHVAVPVDERPLQAILDEDAQPYGWMGIGLQSVMPAHVIYSAVDPNPAGFSRF
CCCEECCCEEEECCCCCHHHHHHCCCCCCCCEECCCHHHHHHHHHHEECCCCCCCCHHHH
WLQDILRTHYNFDGVIFSDDLSMEGASVAGSVVDGARAALAAGCDMVLICNAPDKADQLL
HHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHH
NELDVRIGKASQRRIRRLFGTKAAKDWSKLAQQSAYRQALRTLREARLIA
HHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12910271 [H]