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The map label for this gene is lysN [H]

Identifier: 17545708

GI number: 17545708

Start: 1039746

End: 1041218

Strand: Direct

Name: lysN [H]

Synonym: RSc0989

Alternate gene names: 17545708

Gene position: 1039746-1041218 (Clockwise)

Preceding gene: 17545699

Following gene: 17545709

Centisome position: 27.98

GC content: 69.93

Gene sequence:

>1473_bases
ATGACGCCTTCCTCCCCGATCGTCAGCCTGGATGCCAGGCGTACCGCCGCCCGTCCGGCCGCGGAGCAGTTGCCCGACCC
GATTCCCTCGGCGCAGATGACGCTGGTCGACCAGTTGACCGAGTGGGCGCGCATGCGCATCGACGAGCGCGTGTTCCGCG
CCGGCATGCGCATGCCGTCGATCCGCCAACTGGCCCAGGAGAAGAGCATCTCGCGCTTCACCGTGGTGGAGGCCTATGAG
CGGCTGGTGGCGCAGGGGTATCTCGAATCGCGGCGCGGCTCGGGCTTCTACGTGAAGGAGCGCCAAGCGCCGCTGCCCGA
GGAGCCGCCGGCGCCGCCCGCCAGCGCGCGCAAGATCGACGTGGCCTGGCTGCTGCGCAACATGTTCCACTCGGCCGAGC
CGCGCAAGGCGCCGGGCATCGGCTTCCTGCCCAACGGCTGGCTGGACGGCGAACTGATCGCCAACGCGCTGCGCGCCCTG
GGCCGGCAGAACGGCAACCAGTTCCTGGCCTGGGGCACGCCGCAGGGCTTCCTGCCGCTGCGCCAGCAGCTGCAGACGCG
GCTGGCCGAGCTGGAGATCGGCGCGCGCCCCGACCAGATCGTCATGACCTCCGGCATCACCCAGTCGCTCGACCTGATCG
CGCGCCAGTACGTGCAGCCGGGCGACACGGTGCTGGTGGGCGATCCGGCATGGTTCCTGATGTTCGGCCGCTTCGCCGCG
CAGGGCGCGCAGGTGATCGGCGTGCCGTACACCACCGAGGGGCCGGACCTGGTGGCGCTCGAAGGGCTGGTGCAGGTGCG
CCGACCCAAGCTGCTGGTGATCAATTCGGTGCTGCACAACCCGACCGGCACCTCGCTGTCGGCGGCCAAGGCGTTCCAGC
TGTTGCGGCTGGCCGAGCAGTACGGATTCCTGATCGTCGAAGACGACATCTACGGCGACCTGGCCCCGCCCGGGCACCCG
GCCACGCGGCTGGCGAGCCTGGACCAGCTGCGCCGGGTGATCTACCTCGGCAGCTTTTCCAAGACGCTGGCGGCCAACCT
GCGCGTGGGCTTCATCGCCTGTCATCCGGAGCTGGCCAAGAACCTGACCGACGGCAAGCTGCTGGCCGGGCTCGCCACGC
CGGAGATCAACGAGCGCGTGCTCTACAAGGTGCTGACCGAAGGTCAGTACCGCAAGCACGTCGAGCGCGTGCGCGCCCGG
CTCGACCGCGCCCGCGACGGCGTGCAGCGCAGCCTGGAGCGCCTGGGCCTGAAGCTGTTCGCGCAGCAGGGCGCCGGCAT
GTTCATCTGGGCCGACACCGGCCGCGACACCAACGCCATCGCCCGCGCCGGGCACGAAGAGGGTTACGTGTTCGCGCCGG
GCAGTCTGTTCTCGCCGTCGCAGATGCCCTCGACCTGGATGCGCTTCAATATTGCCACCAGCACCGATCCGGAGATGCTG
CGCTTCCTGGCGGATCAGCTCGAGCGCGGCTGA

Upstream 100 bases:

>100_bases
CGTGGGGGCGGAAAGCCGACCTTGATGGTAGCGAACTGTGGCTGTACAGTACCTGTACACTTTGGCGTGGCGCTTTCTGT
ACAGTTTTTCCGACCTGACC

Downstream 100 bases:

>100_bases
CTCGGCCCGGCCACGGGGCAAGGGGCTTGAAAAACGGCTCCGCCGCCCCATCTCCAGTTCACGCGGACCGCCCGCTGGGT
GCGGTCCGCTTCGCTTTCTC

Product: transcription regulator protein

Products: NA

Alternate protein names: 2-aminoadipate aminotransferase; Alpha-aminoadipate aminotransferase; AAA-AT; AadAT [H]

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MTPSSPIVSLDARRTAARPAAEQLPDPIPSAQMTLVDQLTEWARMRIDERVFRAGMRMPSIRQLAQEKSISRFTVVEAYE
RLVAQGYLESRRGSGFYVKERQAPLPEEPPAPPASARKIDVAWLLRNMFHSAEPRKAPGIGFLPNGWLDGELIANALRAL
GRQNGNQFLAWGTPQGFLPLRQQLQTRLAELEIGARPDQIVMTSGITQSLDLIARQYVQPGDTVLVGDPAWFLMFGRFAA
QGAQVIGVPYTTEGPDLVALEGLVQVRRPKLLVINSVLHNPTGTSLSAAKAFQLLRLAEQYGFLIVEDDIYGDLAPPGHP
ATRLASLDQLRRVIYLGSFSKTLAANLRVGFIACHPELAKNLTDGKLLAGLATPEINERVLYKVLTEGQYRKHVERVRAR
LDRARDGVQRSLERLGLKLFAQQGAGMFIWADTGRDTNAIARAGHEEGYVFAPGSLFSPSQMPSTWMRFNIATSTDPEML
RFLADQLERG

Sequences:

>Translated_490_residues
MTPSSPIVSLDARRTAARPAAEQLPDPIPSAQMTLVDQLTEWARMRIDERVFRAGMRMPSIRQLAQEKSISRFTVVEAYE
RLVAQGYLESRRGSGFYVKERQAPLPEEPPAPPASARKIDVAWLLRNMFHSAEPRKAPGIGFLPNGWLDGELIANALRAL
GRQNGNQFLAWGTPQGFLPLRQQLQTRLAELEIGARPDQIVMTSGITQSLDLIARQYVQPGDTVLVGDPAWFLMFGRFAA
QGAQVIGVPYTTEGPDLVALEGLVQVRRPKLLVINSVLHNPTGTSLSAAKAFQLLRLAEQYGFLIVEDDIYGDLAPPGHP
ATRLASLDQLRRVIYLGSFSKTLAANLRVGFIACHPELAKNLTDGKLLAGLATPEINERVLYKVLTEGQYRKHVERVRAR
LDRARDGVQRSLERLGLKLFAQQGAGMFIWADTGRDTNAIARAGHEEGYVFAPGSLFSPSQMPSTWMRFNIATSTDPEML
RFLADQLERG
>Mature_489_residues
TPSSPIVSLDARRTAARPAAEQLPDPIPSAQMTLVDQLTEWARMRIDERVFRAGMRMPSIRQLAQEKSISRFTVVEAYER
LVAQGYLESRRGSGFYVKERQAPLPEEPPAPPASARKIDVAWLLRNMFHSAEPRKAPGIGFLPNGWLDGELIANALRALG
RQNGNQFLAWGTPQGFLPLRQQLQTRLAELEIGARPDQIVMTSGITQSLDLIARQYVQPGDTVLVGDPAWFLMFGRFAAQ
GAQVIGVPYTTEGPDLVALEGLVQVRRPKLLVINSVLHNPTGTSLSAAKAFQLLRLAEQYGFLIVEDDIYGDLAPPGHPA
TRLASLDQLRRVIYLGSFSKTLAANLRVGFIACHPELAKNLTDGKLLAGLATPEINERVLYKVLTEGQYRKHVERVRARL
DRARDGVQRSLERLGLKLFAQQGAGMFIWADTGRDTNAIARAGHEEGYVFAPGSLFSPSQMPSTWMRFNIATSTDPEMLR
FLADQLERG

Specific function: Catalyzes the transfer of an amino group between 2- oxoadipate (2-OA) and glutamate (Glu) to yield alpha-aminodipate (AAA). It can also transaminate glutamate, leucine, and aromatic amino acids. It also conbtributes in the biosynthesis of other amino acid

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=336, Percent_Identity=27.3809523809524, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI33469970, Length=336, Percent_Identity=27.3809523809524, Blast_Score=96, Evalue=5e-20,
Organism=Escherichia coli, GI1787710, Length=447, Percent_Identity=27.5167785234899, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1790797, Length=482, Percent_Identity=26.3485477178423, Blast_Score=129, Evalue=5e-31,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.39 [H]

Molecular weight: Translated: 54270; Mature: 54139

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPSSPIVSLDARRTAARPAAEQLPDPIPSAQMTLVDQLTEWARMRIDERVFRAGMRMPS
CCCCCCEEEECCHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
IRQLAQEKSISRFTVVEAYERLVAQGYLESRRGSGFYVKERQAPLPEEPPAPPASARKID
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCHH
VAWLLRNMFHSAEPRKAPGIGFLPNGWLDGELIANALRALGRQNGNQFLAWGTPQGFLPL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
RQQLQTRLAELEIGARPDQIVMTSGITQSLDLIARQYVQPGDTVLVGDPAWFLMFGRFAA
HHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHH
QGAQVIGVPYTTEGPDLVALEGLVQVRRPKLLVINSVLHNPTGTSLSAAKAFQLLRLAEQ
CCCEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEHHHHCCCCCCCHHHHHHHHHHHHHHH
YGFLIVEDDIYGDLAPPGHPATRLASLDQLRRVIYLGSFSKTLAANLRVGFIACHPELAK
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCEEEEEEECHHHHC
NLTDGKLLAGLATPEINERVLYKVLTEGQYRKHVERVRARLDRARDGVQRSLERLGLKLF
CCCCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQQGAGMFIWADTGRDTNAIARAGHEEGYVFAPGSLFSPSQMPSTWMRFNIATSTDPEML
HHCCCCEEEEECCCCCHHHHHHCCCCCCEEECCCCCCCCCCCCCCCEEEEECCCCCHHHH
RFLADQLERG
HHHHHHHCCC
>Mature Secondary Structure 
TPSSPIVSLDARRTAARPAAEQLPDPIPSAQMTLVDQLTEWARMRIDERVFRAGMRMPS
CCCCCEEEECCHHHHCCCCHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
IRQLAQEKSISRFTVVEAYERLVAQGYLESRRGSGFYVKERQAPLPEEPPAPPASARKID
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCCCCCCCHH
VAWLLRNMFHSAEPRKAPGIGFLPNGWLDGELIANALRALGRQNGNQFLAWGTPQGFLPL
HHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHH
RQQLQTRLAELEIGARPDQIVMTSGITQSLDLIARQYVQPGDTVLVGDPAWFLMFGRFAA
HHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHHHH
QGAQVIGVPYTTEGPDLVALEGLVQVRRPKLLVINSVLHNPTGTSLSAAKAFQLLRLAEQ
CCCEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEHHHHCCCCCCCHHHHHHHHHHHHHHH
YGFLIVEDDIYGDLAPPGHPATRLASLDQLRRVIYLGSFSKTLAANLRVGFIACHPELAK
CCEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHCCEEEEEEECHHHHC
NLTDGKLLAGLATPEINERVLYKVLTEGQYRKHVERVRARLDRARDGVQRSLERLGLKLF
CCCCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AQQGAGMFIWADTGRDTNAIARAGHEEGYVFAPGSLFSPSQMPSTWMRFNIATSTDPEML
HHCCCCEEEEECCCCCHHHHHHCCCCCCEEECCCCCCCCCCCCCCCEEEEECCCCCHHHH
RFLADQLERG
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA