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The map label for this gene is orn

Identifier: 17545661

GI number: 17545661

Start: 990914

End: 991573

Strand: Direct

Name: orn

Synonym: RSc0942

Alternate gene names: 17545661

Gene position: 990914-991573 (Clockwise)

Preceding gene: 17545657

Following gene: 17545664

Centisome position: 26.66

GC content: 63.03

Gene sequence:

>660_bases
GTGAGCACCCCTCTTTCCCAGCCGGCTGCGGCATCTTCGAGCGCCACCCACGTCACCACCAAAATCGCCGCCAAGAGCGA
CAACAACCTGGTCTGGCTCGACATGGAGATGACCGGCCTGAGCCCCGAGAACGACCGCATCATCGAGGTGGCCATGGTCG
TCACGGACTCGGAGTTGAACGTGCTGGCCGAAGGCCCGGTGCTGGTGATCCACCAGCCGGACGAGATCCTCGACGGCATG
GATGCCTGGAACAAGGGCACGCACGGCCGCTCGGGCCTGATCGACAAGGTGAAGGCCTCGACTACCACCGAAGCGCAGGC
CGAAGCCGATCTGCTGGACTTCCTGAAGAAGTGGGTGCCCAAGAGCAAGTCGCCGATGTGCGGCAACTCCATCTGCCAGG
ACCGTCGCTTCATGGCGCGCTACATGCCCAAGCTGGAGGCGTACTTCCACTACCGCAACCTGGACGTCTCCACGCTCAAG
GAACTTTGCAAACGTTGGCAGCCGGCCATCGCCAAGGGCTTCATCAAGCGCCAGCAGCACACCGCGTACGCCGACATCGT
CGAATCGATCGAAGAACTGCGCTACTACCGCCAGCATTTCATTCGCGACGTGCCGCAGACGCCGGAAGCCGAAGCGCTGG
CCTCCTCGGTCGCGCCGTAA

Upstream 100 bases:

>100_bases
GAGGGCGATCAGGAAGACGGCGGTGAAGGTGGGCATGTGTGGGAACAGCTATCAGATATGCGAAAATTATAGCCTTCCGT
TCATTTCTCAAGGCTTTCGC

Downstream 100 bases:

>100_bases
GCCTCAGACCTGCAGCGGCCTGGCGCGCACGGCGTGCTTGGGCCGCCAGGTCTTGACCACGCTGTCGTGCGTCTCGATGT
AGGGGCCGCCGATCAGGTCG

Product: oligoribonuclease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 219; Mature: 218

Protein sequence:

>219_residues
MSTPLSQPAAASSSATHVTTKIAAKSDNNLVWLDMEMTGLSPENDRIIEVAMVVTDSELNVLAEGPVLVIHQPDEILDGM
DAWNKGTHGRSGLIDKVKASTTTEAQAEADLLDFLKKWVPKSKSPMCGNSICQDRRFMARYMPKLEAYFHYRNLDVSTLK
ELCKRWQPAIAKGFIKRQQHTAYADIVESIEELRYYRQHFIRDVPQTPEAEALASSVAP

Sequences:

>Translated_219_residues
MSTPLSQPAAASSSATHVTTKIAAKSDNNLVWLDMEMTGLSPENDRIIEVAMVVTDSELNVLAEGPVLVIHQPDEILDGM
DAWNKGTHGRSGLIDKVKASTTTEAQAEADLLDFLKKWVPKSKSPMCGNSICQDRRFMARYMPKLEAYFHYRNLDVSTLK
ELCKRWQPAIAKGFIKRQQHTAYADIVESIEELRYYRQHFIRDVPQTPEAEALASSVAP
>Mature_218_residues
STPLSQPAAASSSATHVTTKIAAKSDNNLVWLDMEMTGLSPENDRIIEVAMVVTDSELNVLAEGPVLVIHQPDEILDGMD
AWNKGTHGRSGLIDKVKASTTTEAQAEADLLDFLKKWVPKSKSPMCGNSICQDRRFMARYMPKLEAYFHYRNLDVSTLKE
LCKRWQPAIAKGFIKRQQHTAYADIVESIEELRYYRQHFIRDVPQTPEAEALASSVAP

Specific function: 3'-to-5' exoribonuclease specific for small oligoribonucleotides

COG id: COG1949

COG function: function code A; Oligoribonuclease (3'->5' exoribonuclease)

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain

Homologues:

Organism=Homo sapiens, GI224496106, Length=173, Percent_Identity=49.7109826589595, Blast_Score=183, Evalue=9e-47,
Organism=Escherichia coli, GI87082382, Length=177, Percent_Identity=62.1468926553672, Blast_Score=245, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI17557752, Length=186, Percent_Identity=46.7741935483871, Blast_Score=172, Evalue=1e-43,
Organism=Saccharomyces cerevisiae, GI6323088, Length=205, Percent_Identity=38.5365853658537, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI21355135, Length=177, Percent_Identity=45.7627118644068, Blast_Score=172, Evalue=1e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ORN_RALSO (Q8Y0V1)

Other databases:

- EMBL:   AL646052
- RefSeq:   NP_519063.1
- ProteinModelPortal:   Q8Y0V1
- SMR:   Q8Y0V1
- GeneID:   1219750
- GenomeReviews:   AL646052_GR
- KEGG:   rso:RSc0942
- NMPDR:   fig|267608.1.peg.942
- HOGENOM:   HBG448545
- OMA:   WNKGTHG
- ProtClustDB:   PRK05359
- BioCyc:   RSOL267608:RSC0942-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00045
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR022894
- InterPro:   IPR012337
- SMART:   SM00479

Pfam domain/function: PF00929 Exonuc_X-T; SSF53098 RNaseH_fold

EC number: 3.1.-.- [C]

Molecular weight: Translated: 24506; Mature: 24375

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: ACT_SITE 151-151

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPLSQPAAASSSATHVTTKIAAKSDNNLVWLDMEMTGLSPENDRIIEVAMVVTDSELN
CCCCCCCCCCCCCCCHHHEEEEEECCCCCEEEEEEEECCCCCCCCCEEEEEEEEECCCCC
VLAEGPVLVIHQPDEILDGMDAWNKGTHGRSGLIDKVKASTTTEAQAEADLLDFLKKWVP
EEECCCEEEEECCHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCC
KSKSPMCGNSICQDRRFMARYMPKLEAYFHYRNLDVSTLKELCKRWQPAIAKGFIKRQQH
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TAYADIVESIEELRYYRQHFIRDVPQTPEAEALASSVAP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCC
>Mature Secondary Structure 
STPLSQPAAASSSATHVTTKIAAKSDNNLVWLDMEMTGLSPENDRIIEVAMVVTDSELN
CCCCCCCCCCCCCCHHHEEEEEECCCCCEEEEEEEECCCCCCCCCEEEEEEEEECCCCC
VLAEGPVLVIHQPDEILDGMDAWNKGTHGRSGLIDKVKASTTTEAQAEADLLDFLKKWVP
EEECCCEEEEECCHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHCC
KSKSPMCGNSICQDRRFMARYMPKLEAYFHYRNLDVSTLKELCKRWQPAIAKGFIKRQQH
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
TAYADIVESIEELRYYRQHFIRDVPQTPEAEALASSVAP
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852