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The map label for this gene is bcd [H]

Identifier: 17545644

GI number: 17545644

Start: 976328

End: 978112

Strand: Direct

Name: bcd [H]

Synonym: RSc0925

Alternate gene names: 17545644

Gene position: 976328-978112 (Clockwise)

Preceding gene: 17545643

Following gene: 17545646

Centisome position: 26.27

GC content: 68.8

Gene sequence:

>1785_bases
ATGACCTATCAAGCCCCCGTCAAGGACATGCTGTTCGCAATGAACGAACTGGCCGGCCTGGACAACGTCGCCAGGCTGCC
CGGCTTCGAGGAGGCCACCGCCGACACCGCGCAGGCCGTGCTGGAGGAGAGCGCGCGCTTCACCGGCGAGGTGATCGCCC
CGCTGAACGTGGAGGGCGACCGCAACCCGAGCCGCTGGAAGGATGGCACGGTGACGGCCAGCGCGGGCTTCAAGGAAGCC
TTCCAGCAGTTCGGCCAGGGCGGCTGGCAGGGCGTGCAGCATCCGGTCGAATACGGCGGCCAGGGTTTGCCCAAGCTGAT
CGCCACGGCCTGCATCGAAATGCTGAACGCGGCCAACCTGTCGTTCGCGCTGTGCCCGCTGCTGACCGACGGCGCCATCG
AGGCGCTGCTGACGGCCGGCAGCGAGGCGCAGAAGCAGCTTTATGTGCCGAAGCTGATCTCGGGCGAGTGGACCGGCACG
ATGAACCTGACCGAGCCGCAGGCCGGCTCCGACCTCGCCCTGGTGCGCACGCGTGCCGAGCCGGTGGGCGACGGCACCTT
CAAGGTCTTCGGCACGAAGATCTTCATCACCTGGGGCGAGCACGACATGGCCGGGAACATCGTCCACCTGGTGCTGGCGC
GCACGCCGGGCGCGCCGGAGGGCGTGAAGGGCATTTCGCTGTTCGTGGTGCCCAAGTTCCTGGTCAATGCGGATGGCTCG
CTGGGCGCGCGTAATGACGTGCACTGCGTGTCGATCGAGCACAAGCTCGGCATCAAGGCGAGCCCGACCGCCGTGCTGCA
GTTCGGCGACCATGGCGGCGCCATCGGCACGCTGGTCGGCGAGGAGAACCGCGGCCTGGAATACATGTTCATCATGATGA
ACGCGGCGCGCTATGCGGTCGGCATGCAGGGCATCGGTGTGTCGGAGCGCGCTTACCAGAAGGCTGTGGCCTATGCGCGC
GAGCGCGTGCAGAGCCGTCCGGTGGATGGCTCGGCGGCCAAGGCGGTGCCGATCATCCACCACCCGGACGTCAAGCGCAT
GCTGCTGACCATGCGCGCCATGACCGAAGGCGCCCGCGCGCTGGCCTACGTGGCCGCTGCCGCGTGCGATGCCGGCCACC
ACGCTGCCGATGACGCCACGCGCAAGCAGAACGAGGCGCTGTACGAATTCCTCGTGCCGGTCGTGAAGGGCTGGAGCACC
GAGATGTCGATCGACGTGACCAGCCTCGGCGTGCAGGTGCACGGCGGCATGGGCTTCATCGAGGAGACCGGCGCCGCGCA
GTACTACCGCGATGCGCGCATTCTGCCGATCTACGAAGGCACCACGGCCATCCAGGCCAACGATCTGATCGGCCGCAAGA
CGGTGCGCGATGGCGGTGCGGTGGCGCTGGGCATCTGCGCCGAGATCGCCAGGGTGGAAGCGCAGTTGTCGGCCAAGGGC
GGCGCGCATTGCGAGGCGATGCGCCAGCGCCTGGGCGCGGGCCGCGAGGCGCTGGAATCGGTGGTGCGCTTCGTGGTCGC
GCAGACCAAGGCGCAGCCCAATGCCGTGTTCGCCGGCAGCGTGCCGTACCTGCGGCTGTGCGGCATCGTGCTGTCGGGCT
GGCAGATGGCGCGCGCACTGCTGGCGGCGCTCGACCGCGAGGGCGACGATCCGAACTTCTACGGCGCCAAGATCGCCACG
GCGCGCGTGTTTGCCGACGTGCTGCTGACGCAGGCCCCGGGGATCGCGCAGAGCGTCCTGTCGGGCGGCGAGACCATCGG
CGCCGTGCCGGAAGCGCAGTTCTGA

Upstream 100 bases:

>100_bases
GATCGCCGGGCGCGGCGCGACAGCGCCACCATGCCATGCCGCCGAAGCCGTTTCCGACCCGTTTGGAAACGGCTTTTTCA
TAGAGGGATTGGAGAGAGAC

Downstream 100 bases:

>100_bases
GCCGGCGTTGCCGGCATGAAAAAAGGGAGGCTTCGGCCTCCCTTCTCATTGGCGCCGCGCCGGCGTTCAGGCCAGCGCAG
GCTTGGTCGCCGGTGCCTGG

Product: acyl-CoA dehydrogenase oxidoreductase

Products: NA

Alternate protein names: Butyryl-CoA dehydrogenase; SCAD [H]

Number of amino acids: Translated: 594; Mature: 593

Protein sequence:

>594_residues
MTYQAPVKDMLFAMNELAGLDNVARLPGFEEATADTAQAVLEESARFTGEVIAPLNVEGDRNPSRWKDGTVTASAGFKEA
FQQFGQGGWQGVQHPVEYGGQGLPKLIATACIEMLNAANLSFALCPLLTDGAIEALLTAGSEAQKQLYVPKLISGEWTGT
MNLTEPQAGSDLALVRTRAEPVGDGTFKVFGTKIFITWGEHDMAGNIVHLVLARTPGAPEGVKGISLFVVPKFLVNADGS
LGARNDVHCVSIEHKLGIKASPTAVLQFGDHGGAIGTLVGEENRGLEYMFIMMNAARYAVGMQGIGVSERAYQKAVAYAR
ERVQSRPVDGSAAKAVPIIHHPDVKRMLLTMRAMTEGARALAYVAAAACDAGHHAADDATRKQNEALYEFLVPVVKGWST
EMSIDVTSLGVQVHGGMGFIEETGAAQYYRDARILPIYEGTTAIQANDLIGRKTVRDGGAVALGICAEIARVEAQLSAKG
GAHCEAMRQRLGAGREALESVVRFVVAQTKAQPNAVFAGSVPYLRLCGIVLSGWQMARALLAALDREGDDPNFYGAKIAT
ARVFADVLLTQAPGIAQSVLSGGETIGAVPEAQF

Sequences:

>Translated_594_residues
MTYQAPVKDMLFAMNELAGLDNVARLPGFEEATADTAQAVLEESARFTGEVIAPLNVEGDRNPSRWKDGTVTASAGFKEA
FQQFGQGGWQGVQHPVEYGGQGLPKLIATACIEMLNAANLSFALCPLLTDGAIEALLTAGSEAQKQLYVPKLISGEWTGT
MNLTEPQAGSDLALVRTRAEPVGDGTFKVFGTKIFITWGEHDMAGNIVHLVLARTPGAPEGVKGISLFVVPKFLVNADGS
LGARNDVHCVSIEHKLGIKASPTAVLQFGDHGGAIGTLVGEENRGLEYMFIMMNAARYAVGMQGIGVSERAYQKAVAYAR
ERVQSRPVDGSAAKAVPIIHHPDVKRMLLTMRAMTEGARALAYVAAAACDAGHHAADDATRKQNEALYEFLVPVVKGWST
EMSIDVTSLGVQVHGGMGFIEETGAAQYYRDARILPIYEGTTAIQANDLIGRKTVRDGGAVALGICAEIARVEAQLSAKG
GAHCEAMRQRLGAGREALESVVRFVVAQTKAQPNAVFAGSVPYLRLCGIVLSGWQMARALLAALDREGDDPNFYGAKIAT
ARVFADVLLTQAPGIAQSVLSGGETIGAVPEAQF
>Mature_593_residues
TYQAPVKDMLFAMNELAGLDNVARLPGFEEATADTAQAVLEESARFTGEVIAPLNVEGDRNPSRWKDGTVTASAGFKEAF
QQFGQGGWQGVQHPVEYGGQGLPKLIATACIEMLNAANLSFALCPLLTDGAIEALLTAGSEAQKQLYVPKLISGEWTGTM
NLTEPQAGSDLALVRTRAEPVGDGTFKVFGTKIFITWGEHDMAGNIVHLVLARTPGAPEGVKGISLFVVPKFLVNADGSL
GARNDVHCVSIEHKLGIKASPTAVLQFGDHGGAIGTLVGEENRGLEYMFIMMNAARYAVGMQGIGVSERAYQKAVAYARE
RVQSRPVDGSAAKAVPIIHHPDVKRMLLTMRAMTEGARALAYVAAAACDAGHHAADDATRKQNEALYEFLVPVVKGWSTE
MSIDVTSLGVQVHGGMGFIEETGAAQYYRDARILPIYEGTTAIQANDLIGRKTVRDGGAVALGICAEIARVEAQLSAKGG
AHCEAMRQRLGAGREALESVVRFVVAQTKAQPNAVFAGSVPYLRLCGIVLSGWQMARALLAALDREGDDPNFYGAKIATA
RVFADVLLTQAPGIAQSVLSGGETIGAVPEAQF

Specific function: Unknown

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4501859, Length=418, Percent_Identity=28.2296650717703, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI226958412, Length=411, Percent_Identity=28.4671532846715, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI226958414, Length=378, Percent_Identity=28.5714285714286, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI4501857, Length=399, Percent_Identity=28.5714285714286, Blast_Score=117, Evalue=3e-26,
Organism=Homo sapiens, GI4557233, Length=374, Percent_Identity=29.6791443850267, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI76496475, Length=423, Percent_Identity=29.5508274231678, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI4557235, Length=423, Percent_Identity=29.5508274231678, Blast_Score=110, Evalue=5e-24,
Organism=Homo sapiens, GI21361497, Length=378, Percent_Identity=25.3968253968254, Blast_Score=96, Evalue=8e-20,
Organism=Homo sapiens, GI7656849, Length=380, Percent_Identity=26.3157894736842, Blast_Score=94, Evalue=5e-19,
Organism=Homo sapiens, GI187960098, Length=310, Percent_Identity=25.1612903225806, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI4557231, Length=310, Percent_Identity=25.4838709677419, Blast_Score=80, Evalue=6e-15,
Organism=Escherichia coli, GI87082384, Length=359, Percent_Identity=28.133704735376, Blast_Score=115, Evalue=9e-27,
Organism=Caenorhabditis elegans, GI17508101, Length=408, Percent_Identity=29.4117647058824, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17506239, Length=405, Percent_Identity=27.6543209876543, Blast_Score=121, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI71985184, Length=382, Percent_Identity=28.5340314136126, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI86563381, Length=391, Percent_Identity=28.1329923273657, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI86563383, Length=391, Percent_Identity=27.8772378516624, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI17569725, Length=413, Percent_Identity=25.90799031477, Blast_Score=102, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI17533517, Length=366, Percent_Identity=26.5027322404372, Blast_Score=102, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17538396, Length=451, Percent_Identity=25.7206208425721, Blast_Score=101, Evalue=1e-21,
Organism=Caenorhabditis elegans, GI17534899, Length=425, Percent_Identity=25.1764705882353, Blast_Score=100, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17505929, Length=420, Percent_Identity=27.1428571428571, Blast_Score=98, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17551932, Length=367, Percent_Identity=27.2479564032698, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17570075, Length=353, Percent_Identity=26.0623229461756, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71990804, Length=282, Percent_Identity=27.6595744680851, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI32563615, Length=235, Percent_Identity=30.2127659574468, Blast_Score=87, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71985192, Length=253, Percent_Identity=31.2252964426877, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71982178, Length=300, Percent_Identity=26.3333333333333, Blast_Score=72, Evalue=6e-13,
Organism=Drosophila melanogaster, GI21356377, Length=378, Percent_Identity=29.8941798941799, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI21355753, Length=451, Percent_Identity=26.3858093126386, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI281363737, Length=366, Percent_Identity=27.0491803278689, Blast_Score=105, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24666513, Length=367, Percent_Identity=28.6103542234332, Blast_Score=102, Evalue=7e-22,
Organism=Drosophila melanogaster, GI24660351, Length=420, Percent_Identity=27.3809523809524, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI24646207, Length=370, Percent_Identity=25.6756756756757, Blast_Score=93, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: =1.3.99.2 [H]

Molecular weight: Translated: 62956; Mature: 62824

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTYQAPVKDMLFAMNELAGLDNVARLPGFEEATADTAQAVLEESARFTGEVIAPLNVEGD
CCCCCCHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
RNPSRWKDGTVTASAGFKEAFQQFGQGGWQGVQHPVEYGGQGLPKLIATACIEMLNAANL
CCCCCCCCCEEEECCCHHHHHHHHCCCCCHHCCCHHHHCCCCHHHHHHHHHHHHHHCCCC
SFALCPLLTDGAIEALLTAGSEAQKQLYVPKLISGEWTGTMNLTEPQAGSDLALVRTRAE
CEEEHHHHHHHHHHHHHHCCCHHHHHCCCCCEECCCCCCEEECCCCCCCCCEEEEEECCC
PVGDGTFKVFGTKIFITWGEHDMAGNIVHLVLARTPGAPEGVKGISLFVVPKFLVNADGS
CCCCCEEEEEEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEHHHHHCCCCC
LGARNDVHCVSIEHKLGIKASPTAVLQFGDHGGAIGTLVGEENRGLEYMFIMMNAARYAV
CCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCEEEEEEEHHHHHHH
GMQGIGVSERAYQKAVAYARERVQSRPVDGSAAKAVPIIHHPDVKRMLLTMRAMTEGARA
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
LAYVAAAACDAGHHAADDATRKQNEALYEFLVPVVKGWSTEMSIDVTSLGVQVHGGMGFI
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEECCCCCH
EETGAAQYYRDARILPIYEGTTAIQANDLIGRKTVRDGGAVALGICAEIARVEAQLSAKG
HHCCCHHHHCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
GAHCEAMRQRLGAGREALESVVRFVVAQTKAQPNAVFAGSVPYLRLCGIVLSGWQMARAL
CCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
LAALDREGDDPNFYGAKIATARVFADVLLTQAPGIAQSVLSGGETIGAVPEAQF
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TYQAPVKDMLFAMNELAGLDNVARLPGFEEATADTAQAVLEESARFTGEVIAPLNVEGD
CCCCCHHHHHHHHHHHHCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
RNPSRWKDGTVTASAGFKEAFQQFGQGGWQGVQHPVEYGGQGLPKLIATACIEMLNAANL
CCCCCCCCCEEEECCCHHHHHHHHCCCCCHHCCCHHHHCCCCHHHHHHHHHHHHHHCCCC
SFALCPLLTDGAIEALLTAGSEAQKQLYVPKLISGEWTGTMNLTEPQAGSDLALVRTRAE
CEEEHHHHHHHHHHHHHHCCCHHHHHCCCCCEECCCCCCEEECCCCCCCCCEEEEEECCC
PVGDGTFKVFGTKIFITWGEHDMAGNIVHLVLARTPGAPEGVKGISLFVVPKFLVNADGS
CCCCCEEEEEEEEEEEEECCCCCCCCEEEEEEECCCCCCCCCCCEEEEEEHHHHHCCCCC
LGARNDVHCVSIEHKLGIKASPTAVLQFGDHGGAIGTLVGEENRGLEYMFIMMNAARYAV
CCCCCCEEEEEEECCCCCCCCCCEEEEECCCCCEEEEEECCCCCCCEEEEEEEHHHHHHH
GMQGIGVSERAYQKAVAYARERVQSRPVDGSAAKAVPIIHHPDVKRMLLTMRAMTEGARA
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHH
LAYVAAAACDAGHHAADDATRKQNEALYEFLVPVVKGWSTEMSIDVTSLGVQVHGGMGFI
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEEEEECCCCCH
EETGAAQYYRDARILPIYEGTTAIQANDLIGRKTVRDGGAVALGICAEIARVEAQLSAKG
HHCCCHHHHCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCC
GAHCEAMRQRLGAGREALESVVRFVVAQTKAQPNAVFAGSVPYLRLCGIVLSGWQMARAL
CCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHH
LAALDREGDDPNFYGAKIATARVFADVLLTQAPGIAQSVLSGGETIGAVPEAQF
HHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8655474; 11466286 [H]