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The map label for this gene is ugd [H]

Identifier: 17545632

GI number: 17545632

Start: 964601

End: 965974

Strand: Direct

Name: ugd [H]

Synonym: RSc0913

Alternate gene names: 17545632

Gene position: 964601-965974 (Clockwise)

Preceding gene: 17545631

Following gene: 17545633

Centisome position: 25.96

GC content: 66.45

Gene sequence:

>1374_bases
ATGAGAATCACCATCATCGGTAGCGGCTATGTCGGCCTGGTCACCGGCGCGTGCCTGGCGGAGCTGGGCAACGACGTGTT
CTGCTTCGACGTCGACCAGAAGAAGATCGATCTGCTCAACGCCGGCGGCGTACCGATCTACGAGCCGGGCCTGAAGGAGC
TGATCGACCGCAACCGCACGGCGGGCCGCCTGCAGTTCTCGACGGACGTGGCAGCCAGCGTGGCGCACGGCGACGTGCAG
TTCATCGCCGTGGGCACGCCGCCCGACGAAGACGGCTCGGCCGACCTGAAATACGTGCTGGCGGCCGCCCGCAGCATCGC
CGAGCACATGGACGGCTTCAAGGTGATCGTCGACAAGTCCACCGTGCCGGTGGGCACCGGCGACAAGGTTCGCGCCGTGG
TGGCCGAGGCCCTGGCCGCGCGCGGCAAGTCCGGCATCGGCTTCTCGGTGGTGTCGAACCCCGAGTTCCTGAAGGAGGGG
GCGGCGGTGGACGATTTCATGCGCCCGGACCGCATCGTGCTCGGCACCTACGCCGACGAACCCGGCCTGCGCGCCAAGGC
CACGATGCGCGCGCTGTACGCACCGTTCAACCGCAACCATGAGCGCACGTTCTACATGGACGTGCGTTCGGCCGAATTCA
CCAAGTACGCCGCCAACTCGATGCTGGCCACGCGCATCTCGTTCATGAACGAGATGGCCAACCTGGCCGACAAGGTCGGT
GCCGACATCGAGCTGGTGCGACTGGGCATCGGCTCGGATCCGCGTATCGGCTACAGCTTCCTCTACGCGGGCACGGGCTA
CGGCGGCTCGTGCTTCCCGAAGGATGTGCAGGCGCTGGTGCGGACCGCCCAGGAGCACGGCCAGACGCTGCACGTGCTGG
AAGCGGTCGAGGCCGTCAACGACAAGCAGAAGGAAGTGCTGGTCGGCAAGATCGTCGACCGGCTGGGCGAAGACCTGTCC
GGGCGCACCTTCGCCATCTGGGGCCTGGCATTCAAGCCGAACACCGACGACATGCGCGAGGCGCCGAGCCGCATCGTGAT
CGCCGCGCTGCTCGCGCGCGGCGCCCGCGTGCAGGTCTATGATCCGGTGGCGATGGAGGAGGCCCGCCATGCGCTGGCGA
TCGACTTGTCGCCCGAACAATTGGAACGCGTGACGTTCTGCGCGGGTCAGATGGATGCGCTCAAGCATGCCGACGCGCTC
GTCATCGTGACCGAGTGGAAGGCATTCCGCAGCCCCGACTTCAACGCCGTCAAGGCATTGCTGAAGTCGCCGATGGTGTT
CGACGGCCGCAATCTGTTCGAGCCGCAAGCCATGCGCGACGCGGGGTTCGAATACCAGGCCATCGGGCGCTCCACCCAAT
CGCCTTCGCAGTAA

Upstream 100 bases:

>100_bases
GTACCGAAGCGCTCGGCGGCAGCGGTGGCGCCAGCATGTAATTCAGTCCGGCGTGGCCACGGGGCCGCGCCGGCACGTTT
TCAACTTTTGAATTATTCGC

Downstream 100 bases:

>100_bases
CCGGAGGGCCGCTTTTGCCCGCAGCCATGACCAAGACCACGCTCGCTTCCGAACAGATCCATGCCGCTCGCATCCTCGTG
GTGGGCGACATGATGCTCGA

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 457; Mature: 457

Protein sequence:

>457_residues
MRITIIGSGYVGLVTGACLAELGNDVFCFDVDQKKIDLLNAGGVPIYEPGLKELIDRNRTAGRLQFSTDVAASVAHGDVQ
FIAVGTPPDEDGSADLKYVLAAARSIAEHMDGFKVIVDKSTVPVGTGDKVRAVVAEALAARGKSGIGFSVVSNPEFLKEG
AAVDDFMRPDRIVLGTYADEPGLRAKATMRALYAPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNEMANLADKVG
ADIELVRLGIGSDPRIGYSFLYAGTGYGGSCFPKDVQALVRTAQEHGQTLHVLEAVEAVNDKQKEVLVGKIVDRLGEDLS
GRTFAIWGLAFKPNTDDMREAPSRIVIAALLARGARVQVYDPVAMEEARHALAIDLSPEQLERVTFCAGQMDALKHADAL
VIVTEWKAFRSPDFNAVKALLKSPMVFDGRNLFEPQAMRDAGFEYQAIGRSTQSPSQ

Sequences:

>Translated_457_residues
MRITIIGSGYVGLVTGACLAELGNDVFCFDVDQKKIDLLNAGGVPIYEPGLKELIDRNRTAGRLQFSTDVAASVAHGDVQ
FIAVGTPPDEDGSADLKYVLAAARSIAEHMDGFKVIVDKSTVPVGTGDKVRAVVAEALAARGKSGIGFSVVSNPEFLKEG
AAVDDFMRPDRIVLGTYADEPGLRAKATMRALYAPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNEMANLADKVG
ADIELVRLGIGSDPRIGYSFLYAGTGYGGSCFPKDVQALVRTAQEHGQTLHVLEAVEAVNDKQKEVLVGKIVDRLGEDLS
GRTFAIWGLAFKPNTDDMREAPSRIVIAALLARGARVQVYDPVAMEEARHALAIDLSPEQLERVTFCAGQMDALKHADAL
VIVTEWKAFRSPDFNAVKALLKSPMVFDGRNLFEPQAMRDAGFEYQAIGRSTQSPSQ
>Mature_457_residues
MRITIIGSGYVGLVTGACLAELGNDVFCFDVDQKKIDLLNAGGVPIYEPGLKELIDRNRTAGRLQFSTDVAASVAHGDVQ
FIAVGTPPDEDGSADLKYVLAAARSIAEHMDGFKVIVDKSTVPVGTGDKVRAVVAEALAARGKSGIGFSVVSNPEFLKEG
AAVDDFMRPDRIVLGTYADEPGLRAKATMRALYAPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNEMANLADKVG
ADIELVRLGIGSDPRIGYSFLYAGTGYGGSCFPKDVQALVRTAQEHGQTLHVLEAVEAVNDKQKEVLVGKIVDRLGEDLS
GRTFAIWGLAFKPNTDDMREAPSRIVIAALLARGARVQVYDPVAMEEARHALAIDLSPEQLERVTFCAGQMDALKHADAL
VIVTEWKAFRSPDFNAVKALLKSPMVFDGRNLFEPQAMRDAGFEYQAIGRSTQSPSQ

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=472, Percent_Identity=35.5932203389831, Blast_Score=276, Evalue=4e-74,
Organism=Homo sapiens, GI296040438, Length=374, Percent_Identity=35.5614973262032, Blast_Score=222, Evalue=7e-58,
Organism=Homo sapiens, GI296040443, Length=319, Percent_Identity=35.7366771159875, Blast_Score=186, Evalue=5e-47,
Organism=Escherichia coli, GI1788340, Length=371, Percent_Identity=27.4932614555256, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI48994968, Length=421, Percent_Identity=28.7410926365796, Blast_Score=137, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17560350, Length=464, Percent_Identity=35.9913793103448, Blast_Score=263, Evalue=2e-70,
Organism=Drosophila melanogaster, GI17136908, Length=469, Percent_Identity=34.9680170575693, Blast_Score=270, Evalue=2e-72,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 49548; Mature: 49548

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRITIIGSGYVGLVTGACLAELGNDVFCFDVDQKKIDLLNAGGVPIYEPGLKELIDRNRT
CEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCCCHHHHHHCCCC
AGRLQFSTDVAASVAHGDVQFIAVGTPPDEDGSADLKYVLAAARSIAEHMDGFKVIVDKS
CCEEEECCHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC
TVPVGTGDKVRAVVAEALAARGKSGIGFSVVSNPEFLKEGAAVDDFMRPDRIVLGTYADE
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHCCCCHHHHCCCCEEEEEECCCC
PGLRAKATMRALYAPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNEMANLADKVG
CCCHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ADIELVRLGIGSDPRIGYSFLYAGTGYGGSCFPKDVQALVRTAQEHGQTLHVLEAVEAVN
CCEEEEEECCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEHHHHHHHHHC
DKQKEVLVGKIVDRLGEDLSGRTFAIWGLAFKPNTDDMREAPSRIVIAALLARGARVQVY
CHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEE
DPVAMEEARHALAIDLSPEQLERVTFCAGQMDALKHADALVIVTEWKAFRSPDFNAVKAL
CCHHHHHCCCEEEEECCHHHHHHHHHHCCHHHHHHCCCEEEEEEECHHHCCCCHHHHHHH
LKSPMVFDGRNLFEPQAMRDAGFEYQAIGRSTQSPSQ
HCCCCEECCCCCCCCHHHHHCCCEEEECCCCCCCCCC
>Mature Secondary Structure
MRITIIGSGYVGLVTGACLAELGNDVFCFDVDQKKIDLLNAGGVPIYEPGLKELIDRNRT
CEEEEEECCHHHHHHHHHHHHHCCCEEEEECCCCCEEEEECCCCCCCCCCHHHHHHCCCC
AGRLQFSTDVAASVAHGDVQFIAVGTPPDEDGSADLKYVLAAARSIAEHMDGFKVIVDKS
CCEEEECCHHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEEECC
TVPVGTGDKVRAVVAEALAARGKSGIGFSVVSNPEFLKEGAAVDDFMRPDRIVLGTYADE
CCCCCCCHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHCCCCHHHHCCCCEEEEEECCCC
PGLRAKATMRALYAPFNRNHERTFYMDVRSAEFTKYAANSMLATRISFMNEMANLADKVG
CCCHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
ADIELVRLGIGSDPRIGYSFLYAGTGYGGSCFPKDVQALVRTAQEHGQTLHVLEAVEAVN
CCEEEEEECCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCEEHHHHHHHHHC
DKQKEVLVGKIVDRLGEDLSGRTFAIWGLAFKPNTDDMREAPSRIVIAALLARGARVQVY
CHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHCCCEEEEE
DPVAMEEARHALAIDLSPEQLERVTFCAGQMDALKHADALVIVTEWKAFRSPDFNAVKAL
CCHHHHHCCCEEEEECCHHHHHHHHHHCCHHHHHHCCCEEEEEEECHHHCCCCHHHHHHH
LKSPMVFDGRNLFEPQAMRDAGFEYQAIGRSTQSPSQ
HCCCCEECCCCCCCCHHHHHCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]